Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Download or read book Sequence Analysis Primer written by Michael Ray Gribskov and published by Oxford University Press, USA. This book was released on 1994 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computerized sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the beginner the necessary background to enter this vital field and helps more seasoned researchers to fine-tune their approach. It covers basic data manipulation such as homology searches, stem-loop identification, and protein secondary structure prediction, and is compatible with most sequence analysis programs. A detailed example giving steps for characterizing a new gene sequence provides users with hands-on experience when combined with their current software. The book will be invaluable to researchers and students in molecular biology, genetics, biochemistry, microbiology, and biotechnology.
Download or read book The Yeast Two hybrid System written by Paul L. Bartel and published by Oxford University Press, USA. This book was released on 1997 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, part of the Advances in Molecular Biology series, presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid system. It includes detailed protocols, practical advice on troubleshooting, and suggestions for future development. In addition, it illustrates how to construct an activation domain hybrid library, how to identify mutations that disrupt an interaction, and how to use the system in mammalian cells. Many of the contributors have developed new applications and variations of the technique.
Download or read book Sequence Evolution Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.
Download or read book Computer Analysis of Sequence Data Part I written by Annette M. Griffin and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA sequencing has become increasingly efficient over the years, resulting in an enormous increase in the amount of data gen- ated. In recent years, the focus of sequencing has shifted, from being the endpoint of a project, to being a starting point. This is especially true for such major initiatives as the human genome project, where vast tracts of DNA of unknown function are sequenced. This sheer volume of available data makes advanced computer methods ess- tial to analysis, and a familiarity with computers and sequence ana- sis software a vital requirement for the researcher involved with DNA sequencing. Even for nonsequencers, a familiarity with sequence analysis software can be important. For instance, gene sequences already present in the databases can be extremely useful in the design of cloning and genetic manipulation experiments. This two-part work on Analysis of Data is designed to be a practical aid to the researcher who uses computers for the acquisition, storage, or analysis of nucleic acid (and/or p- tein) sequences. Each chapter is written such that a competent sci- tist with basic computer literacy can carry out the procedure successfully at the first attempt by simply following the detailed pr- tical instructions that have been described by the author. A Notes section, which is included at the end of each chapter, provides advice on overcoming the common problems and pitfalls sometimes enco- tered by users of the sequence analysis software. Software packages for both the mainframe and personal computers are described.
Download or read book Practical Bioinformatics For Beginners From Raw Sequence Analysis To Machine Learning Applications written by Lloyd Wai Yee Low and published by World Scientific. This book was released on 2023-01-17 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next-Generation Sequencing (NGS) is increasingly common and has applications in various fields such as clinical diagnosis, animal and plant breeding, and conservation of species. This incredible tool has become cost-effective. However, it generates a deluge of sequence data that requires efficient analysis. The highly sought-after skills in computational and statistical analyses include machine learning and, are essential for successful research within a wide range of specializations, such as identifying causes of cancer, vaccine design, new antibiotics, drug development, personalized medicine, and increased crop yields in agriculture.This invaluable book provides step-by-step guides to complex topics that make it easy for readers to perform specific analyses, from raw sequenced data to answer important biological questions using machine learning methods. It is an excellent hands-on material for lecturers who conduct courses in bioinformatics and as reference material for professionals. The chapters are standalone recipes making them suitable for readers who wish to self-learn selected topics. Readers gain the essential skills necessary to work on sequenced data from NGS platforms; hence, making themselves more attractive to employers who need skilled bioinformaticians.
Download or read book Sequence Analysis in Molecular Biology written by Gunnar Von Heijne and published by Elsevier. This book was released on 2012-12-02 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence Analysis in Molecular Biology: Treasure Trove or Trivial Pursuit presents the methods for sequence analysis of DNA and proteins. This book contains eight chapters that consider the sequence analysis either directly on a microcomputer or using one of the main sequence/programs data banks. This book starts with a description of the main nucleic acid and protein sequence data banks, followed by a short section on the ""housekeeping aids"" that the computer can provide during a sequencing project. Chapters 4 and 5 deal with nucleic acid and protein sequence analysis. Chapter 6 treats algorithms for homology searching and sequence alignments. Chapter 7 presents some selected examples of how computer modeling can help decide whether an observed sequence pattern is significant or not, and how computer simulation is sometimes used to get a feeling for the behavior of intrinsically complex sequence-dependent processes. Chapter 8 contains some comments on the role of theoretical sequence analysis in molecular biology. This book is directed toward molecular biologists.
Download or read book Sequence Organization in Interaction written by Emanuel A. Schegloff and published by Cambridge University Press. This book was released on 2007 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first in a new series on conversation analysis, the study of talk in interaction. This volume looks at the ways in which turns-at-talk are ordered to make actions take place in conversation.
Download or read book Request Sequences written by Carmen Taleghani-Nikazm and published by John Benjamins Publishing. This book was released on 2006-05-10 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a micro-analytic description of instances of requests in everyday German conversation. Using the framework of CA, the study systematically analyzes the grammatical and syntactical structure of the request-turn and its response and of the conversational exchanges before and within the request base sequence, and the placement of the request sequence within the larger social interaction. Through an empirical analysis of individual cases of request sequences in German, the monograph describes in detail: (a) how speakers employ grammar and syntax as resources to construct turns at talk and accomplish the social action of request; (b) how speakers use grammatical and syntactical forms of the language to coordinate the production of the social action of requests; (c) how speakers use grammar and syntax as interactional resources to manage affiliative and remedial work (i.e., face work) when performing delicate social actions such as requests; and (d) how the context of the request activity impacts the grammatical and syntactical constructions of speakers’ utterances. Additionally, the monograph demonstrates that both the grammatical construction of turns and their placement within the talk are oriented to the sequential context of the interaction.
Download or read book The Base Sequence Class written by Hari Subramaniam and published by . This book was released on 1993 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Learning Basic Genetics with Interactive Computer Programs written by Charles C. Tseng and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, genetics laboratory exercises at the university level focus on mono- and dihybrid crosses and phenotypic analysis—exercises under traditional time, materials, and process constraints. Lately, molecular techniques such as gene cloning, polymerase chain reactions (PCR), and bioinformatics are being included in many teaching laboratories—where affordable. Human chromosome analysis, when present at all, has often been restricted to simple identification of chromosomes by number, through the usual “cut-and-paste” method. Although several online karyotyping (chromosome identification) programs have become available, they are not meaningful for studying the dynamics of the chromosome system, nor do they help students understand genetics as a discipline. The software that accompanies this book has been shown to be an ideal tool for learning about genetics, which requires a combination of understanding, conceptualization, and practical experience.
Download or read book Carcinomas New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 1675 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carcinomas: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Carcinomas: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Carcinomas: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book The Logic of Biochemical Sequencing written by David Blackman and published by CRC Press. This book was released on 1993-10-25 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Logic of Biochemical Sequencing examines how to determine the primary structures of proteins and DNA and use them to stimulate the process of logical problem-solving. It concentrates on sequencing work and stresses the thought processes needed to make sense of what might otherwise be indecipherable data. The book also introduces "biocryptography," which serves as a basis for four short stories that use the results of sequence determinations to provide clues to higher order problems. Problems in the book range from elementary to difficult, and solutions to all problems are provided, many of them completely worked out. The book is an excellent supplementary text for students in a full-year biochemistry course, as well as for biochemists and molecular biologists.
Download or read book Introduction to Genetic Analysis written by Anthony J.F. Griffiths and published by Macmillan. This book was released on 2008 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an introduction to genetic analysis. This book covers contemporary genetics, and helps students understand the essentials of genetics, featuring various experiments, teaching them how to analyze data, and how to draw their own conclusions
Download or read book Los Alamos Science written by and published by . This book was released on with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt:
