Download or read book Bacterial Pathogenesis Part C Identification Regulation and Function of Virulence Factors written by and published by Academic Press. This book was released on 2002-12-05 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences.Key Features* Presents alternatives to mammalian model systems* Discusses virulence and essential gene identification* Defines global gene expression
Download or read book Bacterial Pathogenesis Part C written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Bacteria written by and published by Academic Press. This book was released on 1994-07-19 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology contains contributions covering the wide spectrum of interactions between bacterial pathogens and their eukaryotic hosts. It complements Volume 235, in which methods for the isolation and identification of bacterial pathogens and associated virulence determinants are described. Since the study of bacterial pathogenesis borrows from a great variety of technologies and disciplines, we aim to provide the reader with a representative sample of the most advanced pathogenesis research.
Download or read book Methods in Enzymology written by Sidney P. Colowick and published by . This book was released on 2002 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacterial Pathogenesis Part A Identification and Regulation of Virulence Factors written by and published by Academic Press. This book was released on 1994-05-10 with total page 789 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology presents methods for the isolation and identification of bacterial pathogens and associated virulence determinants. It will enable the researcher to determine if closed genes or isolated gene products are involved in virulence. Major Topics Covered Include * Animal model system to determine bacterial virulence * Epidemiological techniques for the identification of bacterial strains and species * Protocols for the purification of subcellular bacterial products frequently associated with virulence * Determination of the means by which bacteria acquire iron * Methods to generate mutants, to construct isogenic strains by allelic exchange, to identify bacterial genes only expressed during infection of the host, and to study regulation of selected bacterial virulence factors * Methods for the assay of destructive bacterial enzymes and toxins
Download or read book Bacterial Pathogenesis written by and published by . This book was released on 1994 with total page 789 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacterial Pathogenesis Part A written by and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacterial Pathogenesis written by and published by Academic Press. This book was released on 1998-07-01 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established almost 30 years ago, Methods in Microbiology is the most prestigious series devoted to techniques and methodology in the field. Now totally revamped, revitalized, with a new format and expanded scope, Methods in Microbiology will continue to provide you with tried and tested, cutting-edge protocols to directly benefit your research. - Focuses on the methods most useful for the microbiologist interested in the way in which bacteria cause disease - Includes section devoted to 'Approaches to characterising pathogenic mechanisms' by Stanley Falkow - Covers safety aspects, detection, identification and speciation - Includes techniques for the study of host interactions and reactions in animals and plants - Describes biochemical and molecular genetic approaches - Essential methods for gene expression and analysis - Covers strategies and problems for disease control
Download or read book Bacterial Pathogenesis Pt A written by and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Concepts in Bacterial Virulence written by Wayne Russell and published by Karger Medical and Scientific Publishers. This book was released on 2005-01-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades the increase in bacterial resistance has led to the search for novel antibacterial therapies and a better understanding of virulence mechanisms used by pathogens. It has been shown that the interplay between pathogenic bacteria and the host is complex and finely balanced. Successful pathogens can manipulate host homeostasis and normal cell functions using a variety of molecular strategies. This volume of the Karger book series Contributions to Microbiology summarizes some of the most important bacterial virulence mechanisms. Eminent scientists provide an update on recent findings in their fields. This state-of-the-art account will not only attract the interest of clinical and preclinical researchers, but will also be of great value to students with an interest in medicine, biology, chemistry, and infectious diseases.
Download or read book Bacterial Pathogenesis written by Abigail A. Salyers and published by Wiley-Blackwell. This book was released on 1994 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Host defences against bacterial pathogens: defences of body surfaces; Clinical importance of understanding host defences; Preventing contactbetween host and pathogen; Skin and mucosal surfaces: the body's firstline of defence; Special defences of specific mucosal surfaces; Host defences against bacterial pathogens: defences of tissue and blood; Constitutive, nonspecific defences; Induced defences: antibodies, activated macrophages, and cytotoxic t cells; Factors that impair or improve host defences; Virulence factors that promote colonization; What is virulence?; Colonization and invasion of host surfaces; Evading complement, phagocytes, and the andibody response; Virulence factors that damage the host; Exotoxins; Hydrolytic enzymes; Bacterial products that provoke an autoimmune response; Endotoxin and other toxic bacterial cellwall components; Regulation of virulence genes; Types of regulation; Experimental approaches to investigating the host-bacterium interaction; Designing an experimental system for studing the bacterium-host interaction; Measurements of virulence; Identifying a potential virulence factor and that it is impotant for virulence; Vaccines and other approaches to modulating the immune response; Virulence factors and rational design of vaccines; Properties of good vaccines; Passive immunization; Immune stimulants other than vaccines; Antibiotics: mechanisms of action and mechanisms of bacterial resistance; Characteristics of antibiotics; Mechanisms of action of antibiotics; Resistance mechanisms; Transfer of resistance genes; Origin of antibiotic resistance genes; Paradigms of bacterium-host interactions; Diphtheria; Virulence factors; Regulation of toxin production: Treatment and prevention of diphtheria; Scarlet fever, toxic shock syndrome, and the return of severe, invasive streptococcal disease; Fluctuating fortunes of scarlet fever and TSS; Virulence factors; Treatment and prevention; Disease without colonization: food-borne toxines caused by Clostridium bolutinum, Staphylococcus aureus, and Clostridium perfringens; Botulism; Food-borne disease caused by S. aurens and C. perfrigens; Cholera (Vibrio cholerae); Pathogenesis and epidemiology of cholera; Virulence factors; Transcriptional regulation of virulence genes; Treatment and prevention; Whoopingcough (Bordetella pertussis); Whooping cough; Steps in infection; Virulence factors; Regulation of virulence genes; Treatment and prevention; Dysentery caused by Shigella species; Dysentery; Virulence factors; Organization of virulence genes; Regulation of virulence genes; Treatment and prevention; Listeria monocytogenes; Listeriosis; Virulence factors; Organization and regulation of virulence genes; Treatment and prevention; Escherichia coli gastrointestinal infections; The amazing variety of diseases caused by E. coli strains; Serotypes and virotypes; Animal and cell culture models; Virulence factors of ETEC strains; Virulence factors of EAggEC strains; Virulence factor of EPEC strains; Virulence factors of EHEC and EIEC strains; Escherichia coli urinary tract infections; Epidemiology of urinary tract infections; Virulence factors of Uropathogenic E. coli strains; Organization and regulation of virulence genes; Treatment and prevention; Yersinia infections; Pathogenic Yersinia species; Virulence mechanisms; Regulation of virulence genes; Treatment and prevention; Salmonella infections; Salmonella species and serogroups; Diseases caused by species and serotypes of Salmonella; Virulence factors; Regulation of virulence genes; Treatment and prevention; Neisseria gonorrhoeae; Gonorrhea; Virulence factors; Continuing search for a vaccine against gonorrhea; Pseudomonas aeruginosa; The quintessential opportunist; Virulence factors; Future Challenges; Gastric and duodenal ulcers: an infections disease; Revolution in gastroentorology; Virulence factors; Treatment and prevention; Pseudomembranous colitis; Pseudomembranous colitis: a disease caused by antibiotics; Virulence factrs; Treatment and prevention; Lyme disease and syphilis; Lyma disease; Virulence factors; Syphilis and lyme disease: two spirochetal diseases with a similar pathology; Treatment and prevention; Legionnaire's disease; The dark side of modern comforts: air conditioning turns ugly; Virulence factors; Treatment and prevention; Tuberculosis; A disease of the past returns to haunt the future; Spread and progression of TB; M. tuberculosis and its unusual cell wall; Emergenceand treatment of drug-resistant TB; Diagnosis of TB; Virulence factors; Immunity to TB; Streptococcus pneumoniae; Streptococcus pneumoniae: an inflammatory subject; Charateristics of S. pneumoniae; Virulence factors; Treatment and prevention; Streptococcal sore throat, rheumatic fever, and glomerulonephritis; The unsolved riddle of rheumatic fever and glomerulonephritis; Virulence factors; Treatment and prevention; Cell surface structure of bacteria; Phylogenetic diversity of pathogenic bacteria; Nucleic acid-based detection systems; Answers to end-of-chapter questions.
Download or read book The Activities of Bacterial Pathogens in Vivo written by Harry Smith and published by World Scientific. This book was released on 2001 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro . However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo . It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. Sample Chapter(s). Chapter 1.1: Introduction (144 KB). Chapter 1.2: Questions about the Determinants of Bacterial Growth in Vivo (202 KB). Chapter 1.3: Questions about the Production in Vivo of Determinants of Mucosal Colonization, Penetration, Interference with Host Defence and Damage to the Host (179 KB). Chapter 1.4: Sialylation of Gonococcal Lps by Host CMP-NANA and Effect of Lactate: A Paradigm for Investigation of Behaviour in Vivo (191 KB). Chapter 1.5: Concluding Remarks (215 KB). Contents: Introduction: Questions about the Behaviour of Bacterial Pathogens In Vivo (H Smith); DNA Topology and Adaptation of Salmonella Typhimurium to an Intracellular Environment (D G Marshall et al.); New Methods for Studying Bacterial Behaviour In Vivo: The Pathogenesis of Shigella Flexneri Infection: Lessons from In Vitro and In Vivo Studies (D J Philpott et al.); Detection and Analysis of Gene Expression During Infection by In Vivo Expression Technology (D S Merrell & A Camilli); Measurement of Bacterial Gene Expression In Vivo (I Hautefort & J C D Hinton); Identification and Analysis of Bacterial Virulence Genes In Vivo (K E Unsworth & D W Holden); Salmonella Interactions with Host Cells: In Vitro to In Viv o (B B Finlay & J H Brumell); Impact of the New Methods: In Vivo Gene Expression and the Adaptive Response: From Pathogenesis to Vaccines and Antimicrobials (D M Heithoff et al.); Challenge of Investigating Biologically Relevant Functions of Virulence Factors in Bacterial Pathogens (R Moxon & C Tang); Virulence Gene Regulation Inside and Outside (V J DiRita et al.); Evidence for Operation In Vivo of Aspects of Pathogenicity Revealed by Recent Work In Vivo: Potential Use of New Methods: Quorum Sensing and the Population-Dependent Control of Virulence (P Williams et al.); Type III Secretion: A Bacterial Device for Close Combat with Cells of Their Eukaryotic Host (G R Cornelis); Evolution of Microbial Pathogens (J Morschhnuser et al.); The Immune Responses to Bacterial Antigens Encountered In Vivo at Mucosal Surfaces (G Dougan et al.). Readership: Graduate students and researchers in microbiology."
Download or read book Principles of Bacterial Pathogenesis written by Eduardo A. Groisman and published by Academic Press. This book was released on 2001-01-09 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants. - Explains the basic principles of bacterial pathogenesis - Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans - Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors - Presents authoritative treatises of the major disease microorganisms
Download or read book Regulation of Bacterial Virulence written by Michael L. Vasil and published by American Society for Microbiology Press. This book was released on 2012-12-05 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.
Download or read book Bacterial Pathogenesis written by Brenda A. Wilson and published by John Wiley & Sons. This book was released on 2020-08-11 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly anticipated update of the acclaimed textbook draws on the latest research to give students the knowledge and tools to explore the mechanisms by which bacterial pathogens cause infections in humans and animals. Written in an approachable and engaging style, the book uses illustrative examples and thought-provoking exercises to inspire students with the potential excitement and fun of scientific discovery. Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments. A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens.
Download or read book Molecular Mechanisms of Bacterial Virulence written by C.I. Kado and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing body of information on bacteria pathogenic for humans, mammals and plants generated within the past ten years has shown the interesting conservation of newly identified genes that playa direct role in the pathogenic mechanism. In addition to these genes, there are also genes that confer host specificities and other traits important in pathogenesis on these pathogens. In this volume, we have organized the subject areas to best fit the concept on the way bacterial pathogens recognize, interact and invade the host, on the regulation of genes involved in virulence, on the genes involved in the elaboration of toxins and other pathogenic components such as iron sequestering proteins, and on the mechanisms of circumventing the host defense systems. These areas are divided into Sections. Section I covers the first step when the pathogen seeks its host, and Sections II through VI cover subsequent steps leading to pathogenesis while avoiding host defenses. We conclude this work with a chapter summarizing information on examples of virulence mechanisms that are highly conserved.
Download or read book Bacterial Pathogens and Their Virulence Factors written by Douglas I. Johnson and published by Springer. This book was released on 2017-11-23 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Pathogens and their Virulence Factors contains a detailed description of 32 major bacterial pathogens that affect human health and their associated virulence determinants. Chapter 1 gives an overview of the different types and classes of general virulence factors involved in host cell adherence and invasion, dissemination within the host, host cell damage, and evasion of host defense systems, as well as mechanisms by which these virulence factors are regulated. Chapters 2 through 33 give concise descriptions of the disease states associated with the 32 bacterial genera and their major pathogenic species, along with an in-depth description of the individual virulence factors that have been found to be functionally involved in pathogenicity. A detailed bibliography derived from primary literature and review articles accompanies each of these chapters, allowing the reader to delve more deeply into individual pathogens and their virulence determinants. Chapter 34 discusses the exciting possibilities and initial successes of using detailed information on a pathogen’s virulence toolkit to design new therapeutics aimed at specific virulence traits.
