Download or read book Boolean Networks as Predictive Models of Emergent Biological Behaviors written by Jordan C. Rozum and published by Cambridge University Press. This book was released on 2024-03-28 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions – from molecules in gene regulatory networks to species in ecological networks – and the often-incomplete state of system knowledge, such as the unknown values of kinetic parameters for biochemical reactions. Boolean networks have emerged as a powerful tool for modeling these systems. This Element provides a methodological overview of Boolean network models of biological systems. After a brief introduction, the authors describe the process of building, analyzing, and validating a Boolean model. They then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization.

Download or read book Nature Inspired Algorithms and Applied Optimization written by Xin-She Yang and published by Springer. This book was released on 2018-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the state-of-the-art developments in nature-inspired algorithms and their applications in various disciplines, ranging from feature selection and engineering design optimization to scheduling and vehicle routing. It introduces each algorithm and its implementation with case studies as well as extensive literature reviews, and also includes self-contained chapters featuring theoretical analyses, such as convergence analysis and no-free-lunch theorems so as to provide insights into the current nature-inspired optimization algorithms. Topics include ant colony optimization, the bat algorithm, B-spline curve fitting, cuckoo search, feature selection, economic load dispatch, the firefly algorithm, the flower pollination algorithm, knapsack problem, octonian and quaternion representations, particle swarm optimization, scheduling, wireless networks, vehicle routing with time windows, and maximally different alternatives. This timely book serves as a practical guide and reference resource for students, researchers and professionals.

Download or read book Nature Inspired Optimization Algorithms written by Xin-She Yang and published by Elsevier. This book was released on 2014-02-17 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature-Inspired Optimization Algorithms provides a systematic introduction to all major nature-inspired algorithms for optimization. The book's unified approach, balancing algorithm introduction, theoretical background and practical implementation, complements extensive literature with well-chosen case studies to illustrate how these algorithms work. Topics include particle swarm optimization, ant and bee algorithms, simulated annealing, cuckoo search, firefly algorithm, bat algorithm, flower algorithm, harmony search, algorithm analysis, constraint handling, hybrid methods, parameter tuning and control, as well as multi-objective optimization. This book can serve as an introductory book for graduates, doctoral students and lecturers in computer science, engineering and natural sciences. It can also serve a source of inspiration for new applications. Researchers and engineers as well as experienced experts will also find it a handy reference. - Discusses and summarizes the latest developments in nature-inspired algorithms with comprehensive, timely literature - Provides a theoretical understanding as well as practical implementation hints - Provides a step-by-step introduction to each algorithm

Download or read book Probabilistic Boolean Networks written by Ilya Shmulevich and published by SIAM. This book was released on 2010-01-21 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive treatment of probabilistic Boolean networks, unifying different strands of current research and addressing emerging issues.

Download or read book Biomolecular Networks written by Luonan Chen and published by John Wiley & Sons. This book was released on 2009-06-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.

Download or read book Single Cell Based Models in Biology and Medicine written by Alexander Anderson and published by Springer Science & Business Media. This book was released on 2007-08-08 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at postgraduate students in a variety of biology-related disciplines, this volume presents a collection of mathematical and computational single-cell-based models and their application. The main sections cover four general model groupings: hybrid cellular automata, cellular potts, lattice-free cells, and viscoelastic cells. Each section is introduced by a discussion of the applicability of the particular modelling approach and its advantages and disadvantages, which will make the book suitable for students starting research in mathematical biology as well as scientists modelling multicellular processes.

Download or read book Nature inspired Metaheuristic Algorithms written by Xin-She Yang and published by Luniver Press. This book was released on 2010 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern metaheuristic algorithms such as bee algorithms and harmony search start to demonstrate their power in dealing with tough optimization problems and even NP-hard problems. This book reviews and introduces the state-of-the-art nature-inspired metaheuristic algorithms in optimization, including genetic algorithms, bee algorithms, particle swarm optimization, simulated annealing, ant colony optimization, harmony search, and firefly algorithms. We also briefly introduce the photosynthetic algorithm, the enzyme algorithm, and Tabu search. Worked examples with implementation have been used to show how each algorithm works. This book is thus an ideal textbook for an undergraduate and/or graduate course. As some of the algorithms such as the harmony search and firefly algorithms are at the forefront of current research, this book can also serve as a reference book for researchers.

Download or read book Elements of Mathematical Ecology written by Mark Kot and published by Cambridge University Press. This book was released on 2001-07-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Elements of Mathematical Ecology provides an introduction to classical and modern mathematical models, methods, and issues in population ecology. The first part of the book is devoted to simple, unstructured population models that ignore much of the variability found in natural populations for the sake of tractability. Topics covered include density dependence, bifurcations, demographic stochasticity, time delays, population interactions (predation, competition, and mutualism), and the application of optimal control theory to the management of renewable resources. The second part of this book is devoted to structured population models, covering spatially-structured population models (with a focus on reaction-diffusion models), age-structured models, and two-sex models. Suitable for upper level students and beginning researchers in ecology, mathematical biology and applied mathematics, the volume includes numerous clear line diagrams that clarify the mathematics, relevant problems thoughout the text that aid understanding, and supplementary mathematical and historical material that enrich the main text.

Download or read book The Balance of Nature written by Stuart L. Pimm and published by University of Chicago Press. This book was released on 1991 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why "the balance of nature"? Resilience. Temporal variability and the individual species. The effects of food-web structure. The variability of the environment. Nonlinear dynamics, strange attractors, and chaos. Extinctions. Species differences and community structure as explanations of why introductions fail. Patterns in species composition. Food-web structure and community persistence. Community assembly; or why are there so many kinds of communities? Small-scale experimental removals of species. Food webs and resistance. Changes in total density and species composition. The consequences of introductions and extinctions. Multispecies models and their limitations. Conclusions and caveats.

Download or read book Self organization and Emergence in Life Sciences written by Bernard Feltz and published by Springer Science & Business Media. This book was released on 2006-07-10 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-organization constitutes one of the most important theoretical debates in contemporary life sciences. The present book explores the relevance of the concept of self-organization and its impact on such scientific fields as: immunology, neurosciences, ecology and theories of evolution. Historical aspects of the issue are also broached. Intuitions relative to self-organization can be found in the works of such key western philosophical figures as Aristotle, Leibniz and Kant. Interacting with more recent authors and cybernetics, self-organization represents a notion in keeping with the modern world's discovery of radical complexity. The themes of teleology and emergence are analyzed by philosophers of sciences with regards to the issues of modelization and scientific explanation. The implications of self-organization for life sciences are here approached from an interdisciplinary angle, revealing the notion as already rewarding and full of promise for the future.

Download or read book Large Scale Structure And Dynamics Of Complex Networks From Information Technology To Finance And Natural Science written by Alessandro Vespignani and published by World Scientific. This book was released on 2007-06-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the culmination of three years of research effort on a multidisciplinary project in which physicists, mathematicians, computer scientists and social scientists worked together to arrive at a unifying picture of complex networks. The contributed chapters form a reference for the various problems in data analysis visualization and modeling of complex networks.

Download or read book Complementary Variational Principles written by A. M. Arthurs and published by Oxford University Press, USA. This book was released on 1980 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Theoretical Ecology written by Robert McCredie May and published by . This book was released on 1976 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ecosystem Ecology written by Sven Erik Jørgensen and published by Academic Press. This book was released on 2009-07-25 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jorgensen's Ecosystem Ecology provides a thorough and comprehensive overview of the world's aquatic and terrestrial ecosystems. This derivative volume based on the best-selling Encyclopedia of Ecology (published 2008) is the only book currently published that provides an overview of the world's ecosystems in a concise format. - Provides an overview of the world's ecosystems in a concise format - Covers aquatic and terrestrial ecosystems - Based on the best-selling Encyclopedia of Ecology - Full-color figures and tables support the text and aid in understanding

Download or read book Mathematical Tools for Understanding Infectious Disease Dynamics written by Odo Diekmann and published by Princeton University Press. This book was released on 2013 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains how to translate biological assumptions into mathematics to construct useful and consistent models, and how to use the biological interpretation and mathematical reasoning to analyze these models. It shows how to relate models to data through statistical inference, and how to gain important insights into infectious disease dynamics by translating mathematical results back to biology.

Download or read book The Dynamics of Biological Systems written by Arianna Bianchi and published by Springer Nature. This book was released on 2019-10-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.

Download or read book Exchange Rate Theory written by Paul de Grauwe and published by Wiley-Blackwell. This book was released on 1993-01-01 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Exchange Rate Theory presents a novel and elegant theory to explain the excessive variability of foreign exchange rate returns. The theory is novel in the sense that it focuses on interaction between market agents as the primary source of the variability in those speculative prices. It is shown that simple interactions between market participants using different information is sufficient to generate deterministic chaos." "In the first part of this book the authors survey existing exchange rate theories and ask whether these theories are useful in explaining actual exchange rate movements. They demonstrate that the 1970s were characterized by the belief that exchange rates could be understood by an analysis of the fundamentals (inflation rates, interest rates and monetary policy). Subsequently, this belief has all but disappeared but researchers have been content to analyze the statistical properties of exchange rates, abandoning the theory and the models." "The second part of the book uses chaos theory to construct an innovative framework for the understanding of exchange markets. These models, which integrate fundamentalism and chartism, create complex exchange rate movements which appear to be random. These models are used to explain several of the anomalies observed in exchange rate markets and to evaluate the possibility of exchange rate prediction."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved