Download or read book Atlas of Steroid Structure written by William L. Duax and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: model. In general, the mean atomic positions and the geometrical parameters calculated from them are more accurate if the more sophisticated anisotropic model has been used for the thermal motion during structure refinement. Low temperature data collection also results in more accurately determined structures. By decreasing the temperature at which data is collected, the intensities and number of data observed is increased. Since hydrogen atoms have only a single electron, they scatter X-rays very weakly, and they can be observed experimentally only if the data are of good quality. Finally, in the absence of systematic errors in data collection or refinement, tae greater the number of observed data relative to the number of independent atoms, the better the atomic resolution will be. Table 1 is a summary of the information used in assessing the reliability of a structure. Neutron diffraction is the result of interaction of atomic nuclei with a neutron beam. The intensi ty of the diffracted beam is not proportional to atomic number. Hydrogen, deuterium, carbon, oxygen and nitrogen scatter neutrons with almost equal intensity. In addition, hydrogen and deuterium scatter out of phase so that they can be distinguished wita high precision. 20-Methyl-5-pregnene-3S,20-diol (PR104N) is the only steroid which has been the subject of a neutron diffraction study. The study was undertaken to examine the stereospecificity of Grignard addition using deuterated reagent. Data were collected at 123°K.
Download or read book Molecular Structure and Biological Activity of Steroids written by Martin Bohl and published by CRC Press. This book was released on 2018-01-18 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.
Download or read book Structure Based Drug Design written by P.W. Codding and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structure-Based Drug Design brings together scientists working on different aspects of the subject, demonstrating the necessary collaboration and interdisciplinary approach to this complex area. The focus is on X-ray crystallographic and computational approaches. The general aspects of these approaches are introduced in the first six articles. The remaining articles provide examples of the application of X-ray crystallography, molecular modelling, molecular dynamics, QSAR, database analysis, and homology modelling. The papers cover a wealth of interesting problems in the design of new and enhanced pharmaceuticals.
Download or read book Steroid Analysis written by Hugh L. J. Makin and published by Springer Science & Business Media. This book was released on 2010-06-04 with total page 1240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this handbook concentrates on the analysis of steroids in biological fluids. It offers analysis of low levels of steroid analytes in biological fluids. This new edition also provides an extra chapter on pharmaceutical aspects of steroid analysis. Coverage details spectroscopic and other methods, including UV and IR absorption spectroscopy, NMR spectroscopy, mass spectrometry, X-ray diffraction, chromatography and immunoassay of steroids.
Download or read book Terpenoids and Steroids written by James R Hanson and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Terpenoids and Steroids written by K H Overton and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1972 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Structure Correlation written by Hans-Beat Bürgi and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book leaves the conventional view of chemical structures far behind: it demonstrates how a wealth of valuable, but hitherto unused information can be extracted from available structural data. For example, a single structure determination does not reveal much about a reaction pathway, but a sufficiently large number of comparable structures does. Finding the 'right' question is as important as is the intelligent use of crystallographic databases. Contributions by F.H. Allen, T.L. Blundell, I.D. Brown, H.B. Bürgi, J.D. Dunitz, L. Leiserowitz and others, authoritatively discuss the structure correlation method as well as illustrative results in detail, covering such apparently unrelated subjects as * Bond strength relations in soldis * Crystal structure prediction * Reaction pathways of organic molecules * Ligand/receptor interactions and enzyme mechanisms This book will be useful to the academic and industrial reader alike. It offers both fundamental aspects and diverse applications of what will surely become a powerful branch of structural chemistry.
Download or read book Proceedings of the Fourth International Congress on Hormonal Steroids written by V. H. T. James and published by Elsevier. This book was released on 2013-10-22 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fourth International Congress on Hormonal Steroids contains plenary speeches and symposia from the Fourth International Congress on Hormonal Steroids held in Mexico City in September 1974
Download or read book Catalog of Copyright Entries Third Series written by Library of Congress. Copyright Office and published by Copyright Office, Library of Congress. This book was released on 1977 with total page 1482 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormones and the Fetus written by J. R. Pasqualini and published by Elsevier. This book was released on 2013-10-22 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume One of Hormones and the Fetus contained a generalization of the role of hormones during fetal life. In this second volume, the main topics focus on hormonal binding to fetal and maternal plasma proteins, amniotic fluid and placenta; the presence of hormone receptors in the fetal compartment; and the mechanism of action of various hormones in different target tissues of the fetus and placenta. This up-to-date information is of major importance in the study of hormonal activity in fetal life, and the biological effect of hormones through the receptor. The mechanism of fetal sexual differentiation, in which hormones play an important role, is extensively covered.
Download or read book Terpenoids and Steroids written by Chemical Society (Great Britain) and published by Royal Society of Chemistry. This book was released on 1974 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 90 years The Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Biochemical Actions of Hormones V6 written by Gerald Litwack and published by Elsevier. This book was released on 2012-12-02 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Actions of Hormones, Volume VI is a 10-chapter text that summarizes the regulation of protein kinases and phosphoprotein phosphatases and the relationship of the endocrines to cancer. This volume describes first the precise structures of steroid hormones and carcinogens. The subsequent chapters cover the hormonal regulation of chemical carcinogenesis; the importance of steroid hormones as growth factors for mammary tumors; the effects of steroid hormones in the central nervous system; and the properties of the purified estrogen receptor. A chapter highlights the biochemical actions of neurohypophysial hormones and neurophysin. Another chapter presents the biochemistry and physiology of cytokinin, a plant hormone. The final chapter exemplifies the multihormonal systems by control of the a2u-globulin produced in the liver. This book will be of great value to endocrinologists.
Download or read book Analysis of Sterols and Other Biologically Significant Steroids written by W. David Nes and published by . This book was released on 1989 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Sterols and Other Biologically Significant Steroids ...
Download or read book Protein ligand Interactions Structure and Spectroscopy written by Stephen E. Harding and published by Oxford University Press, USA. This book was released on 2001 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text on protein-ligand interactions offers a selection of the most useful and easily applied methods and acts as a guide to the principal techniques used.
Download or read book PROPHET Molecules written by and published by . This book was released on 1985 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction to Spectroscopic Methods for the Identification of Organic Compounds written by F. Scheinmann and published by Elsevier. This book was released on 2013-10-22 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Spectroscopic Methods for the Identification of Organic Compounds, Volume 2 covers the theoretical aspects and some applications of certain spectroscopic methods for organic compound identification. This book is composed of 10 chapters, and begins with an introduction to the structure determination from mass spectra. The subsequent chapter presents some mass spectrometry seminar problems and answers. This presentation is followed by discussions on the problems concerning the application of UV spectroscopy and electron spin resonance spectroscopy. Other chapters deal with some advances and development in NMR spectroscopy and the elucidation of structural formula of organic compounds by a combination of spectral methods. The final chapter surveys seminar problems and answers in the identification of organic compounds using NMR, IR, UV and mass spectroscopy. This book will prove useful to organic and analytical chemists.
