Download or read book Atkinson s Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2021-10-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Download or read book Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2012-09-18 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson and published by Academic Press. This book was released on 2007 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. Offers an expanded regulatory section that addresses US and international issues and guidelines. Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.
Download or read book Clinical Pharmacology written by Kenneth L. Melmon and published by . This book was released on 1975 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Treatment written by Graeme S. Avery and published by . This book was released on 1976 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Pharmacology written by Kenneth Lloyd Melmon and published by . This book was released on 1978 with total page 1146 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Pharmacology and Therapeutics written by Gerard A. McKay and published by John Wiley & Sons. This book was released on 2020-11-03 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease. Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making. Presents an up-to-date review of drug use across all major clinical disciplines Offers a timely overview of clinical drug trials and development Provides new clinical scenarios to relate chapter content to real-life application Contains colour-coded “Key Points” and “Prescribing Points” to highlight important information Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrations Lecture Notes: Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.
Download or read book Melmon and Morrelli s Clinical Pharmacology written by Kenneth L. Melmon and published by McGraw-Hill/Appleton & Lange. This book was released on 2000 with total page 1458 pages. Available in PDF, EPUB and Kindle. Book excerpt: -- Perfect for the student, primary care practitioner, and pharmacist who needs both basic and clinical information to apply therapeutics-- A new overview chapter -- plus practical steps required for optimal therapeutic decisions-- Coverage of newly emerging advances in therapeutics-- A new look at cost/benefit analysis of therapy-- Increased emphasis on drug interactions, and much more.
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson, Jr. and published by Elsevier. This book was released on 2011-04-28 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products
Download or read book Avery s Drug Treatment written by T. M. Speight and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Pharmacology Essentials written by Evan Begg and published by Lippincott Williams & Wilkins. This book was released on 2000 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Melmon and Morrelli s Clinical Pharmacology written by Kenneth L. Melmon and published by New York : Pergamon Press. This book was released on 1992 with total page 1141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioequivalence and Statistics in Clinical Pharmacology written by Scott D. Patterson and published by CRC Press. This book was released on 2017-03-27 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how, and why these studies are performed as part of drug development; and demonstrates the methods using real world examples. Drawing on knowledge gained directly from working in the pharmaceutical industry, the authors set the stage by describing the general role of statistics. Once the foundation of clinical pharmacology drug development, regulatory applications, and the design and analysis of bioequivalence trials are established, including recent regulatory changes in design and analysis and in particular sample-size adaptation, they move on to related topics in clinical pharmacology involving the use of cross-over designs. These include, but are not limited to, safety studies in Phase I, dose-response trials, drug interaction trials, food-effect and combination trials, QTc and other pharmacodynamic equivalence trials, proof-of-concept trials, dose-proportionality trials, and vaccines trials. This second edition addresses several recent developments in the field, including new chapters on adaptive bioequivalence studies, scaled average bioequivalence testing, and vaccine trials. Purposefully designed to be instantly applicable, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition provides examples of SAS and R code so that the analyses described can be immediately implemented. The authors have made extensive use of the proc mixed procedures available in SAS.
Download or read book Principles and Practice of Clinical Research written by John I. Gallin and published by Elsevier. This book was released on 2011-04-28 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government
Download or read book Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2012-09-18 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals, this text includes examples to demonstrate the central role of pharmokinetic principles in both clinical practice and drug development.
Download or read book Small Molecule Therapy for Genetic Disease written by Jess G. Thoene and published by Cambridge University Press. This book was released on 2010-08-23 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoene summarises the substantial work that has been accomplished in the treatment of inborn errors of metabolism with simple molecules. This handbook will enable interested clinician scientists to rapidly survey the field, thus ascertaining what has been done as well as future directions for therapeutic research. Its important introductory chapters discuss the infrastructure of the field. The book closely analyses the cofactors used to augment the function of defective enzymes and the compounds that are able to utilise an alternative pathway in order to avoid the consequences of the metabolic block present in the patient. Among other therapies, the authors discuss the use of zinc and tetrathiomolybdate to treat Wilson's disease and the use of cysteamine to treat nephropathic cystinosis.
Download or read book Nurse Anesthesia E Book written by John J. Nagelhout and published by Elsevier Health Sciences. This book was released on 2017-05-27 with total page 1312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain a thorough understanding of nursing anesthesia with the most comprehensive text on the market. Written by leading expert, John Nagelhout, CRNA, PhD, FAAN, and new contributing author Sass Elisha, EdD, CRNA, Nurse Anesthesia, 6th Edition features both scientific principles and evidence-based material. Inside you’ll find a solid introduction to the history, education, and legal issues of nurse anesthetist, its scientific foundations, equipment and monitoring, and preoperative evaluation and preparation of the patient. This new edition includes chapters on patient centered care and cultural competence, additional drugs of interest, blood and blood component therapy, anesthesia management for patients with cardiac devices, anesthesia for robotic surgery, anesthesia for transplant surgery and organ procurement, and physiology and management of acute and chronic pain. Not only a key reference for practicing nurse anesthetists, this bestseller prepares you for certification and today's clinical anesthesia practice. New coverage includes the latest specifics of pharmacokinetics, drug delivery systems, opiate antagonists, and key induction drugs. Updated information on patient safety, monitoring, and pharmacology. Unique! Expert CRNA authors provide the current clinical information that you will use in daily practice. Over 700 tables and boxes highlight the most essential information in a quick, easy-to-reference format. Easy-to-use organization covers basic principles first, and builds on those with individual chapters for each surgical specialty. Updated TJC standards for monitoring and administering moderate sedation/analgesia. NEW! Expanded content includes; non-OR anesthesia, acute and chronic pain management, anesthesia implications of complementary and alternative medicine, robotic surgery, new and less invasive procedures in interventional radiography, implications of modern implanted cardiac devices, and more! NEW! Full-color design and figures clarify difficult concepts and give the text a contemporary look and feel. NEW! Co-author Sass Elisha brings a fresh perspective to this edition.
