Download or read book Atherosclerotic Carotid Plaque Assessment with Multidetector Computed Tomography Angiography written by Thomas Thijs Weert and published by . This book was released on 2009 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis evaluates the role of MDCT angiography in 1) the depiction of atherosclerotic disease and subsequent luminal stenosis in the arteries that supplies the brain with blood, and 2) the assessment of atherosclerotic plaque features that have been related to plaque vulnerability. The studies can be subdivided in three main categories: 1) optimization of data acquisition protocol, 2) validation studies, including assessment of the accuracy of MDCTA in comparison to histology and interobserver studies, and 3) clinical cross-sectional studies. From the first part of this thesis we can conclude that an optimal protocol for MDCT angiography of the supra-aortic arteries incorporates the use of 80 ml contrast material and a 40 ml saline bolus chaser, a craniocaudal scan direction, and in respect to atherosclerotic carotid plaque imaging a tube current of 120 kVp and an intermediate reconstruction algorithm. The second part of this thesis allows to conclude that MDCTA is capable of characterizing and quantifying plaque and plaque component areas in good correlation with histology. However, lipid core can only be adequately quantified in mildly calcified plaques, and in vivo assessment of atherosclerotic plaque and plaque component volumes is feasible with a moderate reproducibility. In addition we can conclude that, with MDCT angiography, intracranial carotid artery calcifications can reproducibly be quantified and that carotid plaque surface morphology can be assessed with a high reproducibility. In the third part of this thesis we evaluated the characteristics of possible MDCTA-assessed plaque parameters (the volume of intracranial calcifications, carotid plaque morphology, and carotid plaque volume and plaque component volumes). Associations were found with several cardiovascular risk factors. Some plaque parameters were related to the presence and type of cerebrovascular symptomatology. We conclude that atherosclerotic plaque parameters can be imaged adequately with MDCTA. These parameters seem to have a possible additional value, besides the degree of stenosis, as a marker of atherosclerotic disease and as predictor of (recurrent) ischemic cerebrovascular events.
Download or read book Multi Modality Atherosclerosis Imaging and Diagnosis written by Luca Saba and published by Springer Science & Business Media. This book was released on 2013-09-13 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is one of the leading causes of death in the world, resulting mostly from the sudden ruptures of atherosclerosis carotid plaques. Understanding why and how plaque develops and ruptures requires a multi-disciplinary approach such as radiology, biomedical engineering, medical physics, software engineering, hardware engineering, pathological and histological imaging. Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment presents a new dimension of understanding Atherosclerosis in 2D and 3D. This book presents work on plaque stress analysis in order to provide a general framework of computational modeling with atherosclerosis plaques. New algorithms based on 3D and 4D Ultrasound are presented to assess the atherosclerotic disease as well as very recent advances in plaque multimodality image fusion analysis. The goal of Multi-Modality Atherosclerosis Imaging, Diagnosis and Treatment is to fuse information obtained from different 3D medical image modalities, such as 3D US, CT and MRI, providing the medical doctor with some sort of augmented reality information about the atherosclerotic plaque in order to improve the accuracy of the diagnosis. Analysis of the plaque dynamics along the cardiac cycle is also a valuable indicator for plaque instability assessment and therefore for risk stratification. 4D Ultrasound, a sequence of 3D reconstructions of the region of interest along the time, can be used for this dynamic analysis. Multimodality Image Fusion is a very appealing approach because it puts together the best characteristics of each modality, such as, the high temporal resolution of US and the high spatial resolutions of MRI and CT.
Download or read book Magnetic Resonance Imaging and Multi detector Computed Tomography Angiography of the Atherosclerotic Plaque at the Carotid Artery Optimization Validation and Clinical Implication written by Mohamed Ouhlous and published by . This book was released on 2009 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book 3D Imaging Technologies in Atherosclerosis written by Rikin Trivedi and published by Springer. This book was released on 2015-09-23 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis represents the leading cause of mortality and morbidity in the world. Two of the most common, severe, diseases that may occur, acute myocardial infarction and stroke, have their pathogenesis in the atherosclerosis that may affect the coronary arteries as well as the carotid/intra-cranial vessels. Therefore, in the past there was an extensive research in identifying pre-clinical atherosclerotic diseases in order to plan the correct therapeutical approach before the pathological events occur. In the last 20 years imaging techniques and in particular Computed Tomography and Magnetic Resonance had a tremendous improvement in their potential. In the field of the Computed Tomography the introduction of the multi-detector-row technology and more recently the use of dual energy and multi-spectral imaging provides an exquisite level of anatomic detail. The MR thanks to the use of strength magnetic field and extremely advanced sequences can image human vessels very quickly while offering an outstanding contrast resolution.
Download or read book Multidetector Row CT Angiography written by Roberto Passariello and published by Springer Science & Business Media. This book was released on 2005-08-02 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidetector-row CT has dramatically improved the results of computed tomography in all clinical applications, but its beneficial impact has been most striking in vascular imaging. The simplicity of acquisition and the wide availability of equipment make this modality especially suitable for routine clinical application. In this book the basic aspects of multidetector-row CT angiography are comprehensively reviewed. Individual chapters are included on technical principles, image processing techniques and contrast agent administration. All clinical applications are then discussed in depth, with lucid descriptions of the examination technique for particular clinical indications and of the findings that characterize specific diseases. Limitations and advantages in comparison with other imaging modalities are considered. A large number of high-quality black and white and color illustrations help to explain the clinical findings.
Download or read book Imaging of Carotid Artery Stenosis written by Bernhard Schaller and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is an up-to-date reference work on imaging in carotid artery stenosis written by internationally renowned experts. The authors take the reader step-by-step through illustrated descriptions of state-of-the-art imaging techniques that they have helped to develop and demonstrate that these techniques are crucial in the management of patients. This book covers all facets of imaging in carotid artery stenosis and gives an outlook to future aspects. At the end of each chapter, special "take-home-messages" offer quick help in daily practice.
Download or read book Imaging Coronary Atherosclerosis written by Stephen J. Nicholls and published by Springer. This book was released on 2014-06-04 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 50 years, coronary angiography has been the mainstay of diagnosing and quantifying the extent of coronary artery disease. However appreciation of the inherent limitations of conventional angiography has led to a plethora of new imaging modalities, each with their relative strengths and potential pitfalls. Advances in these techniques have given clinicians, as well as researchers, an overwhelming amount of information and the need for thoughtful interpretation. This outstanding book provides a comprehensive overview of the current status of imaging of coronary atherosclerosis. Covering the wide variety of available imaging modalities, the book provides state-of-the-art knowledge from leading authorities in each area. In their discussion, the authors include both invasive and non-invasive modalities, including the gold standard coronary angiography, the growing field of IVUS, and novel techniques such as functional imaging, molecular imaging, and the integration of biomarkers. The key concepts and practical information given in this volume will provide the reader with the necessary understanding to choosing appropriate imaging studies and building confidence in their skill set with each.
Download or read book Non invasive Imaging of Atherosclerotic Plaque Prior to Percutaneous Interventional Procedures written by Gary Y. H. Liew and published by . This book was released on 2013 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is a disease which has impacted our health like no other in the last half century. The detection of this disease range from biomarkers, stress-testing to invasive imaging by way of angiography or other intravascular methods. In recent years, technological developments in multi-detector computed tomography (MDCT) and magnetic resonance imaging (MRI) has allowed us to visualize atherosclerotic plaque noninvasively. This has great appeal as they carry very little risk in comparison to invasive angiography and provide information of plaque composition in addition to stenosis severity. The identification of plaques which are high-risk or 'vulnerable' to subsequent complications such as myocardial infarction or stroke would be highly valuable in our approach to incremental risk assessment and perhaps future treatment. Certain procedures in interventional cardiology such as saphenous vein graft (SVG) intervention and carotid stenting carry increased risk of embolic complications compared to coronary stenting. Non-invasive imaging could potentially identify certain plaque features which may be associated with an increased risk of embolization before embarking on such procedures. This thesis examines the utility of MDCT and MRI in atherosclerotic plaque imaging prior to SVG interventions and carotid stenting. Our initial chapter investigates the angiographic parameters associated with embolization during SVG intervention. We correlate the amount of debris captured by distal protection devices during intervention with angiographic markers and subsequently, with impaired blood flow by way of Thrombolysis In Myocardial Infarction (TIMI) frame count. Our next step involved the accuracy and reproducibility of MDCT and MRI in plaque quantification in comparison to our reference standard of intravascular ultrasound. We measured the luminal, vessel wall and plaque areas, and then calculated the resultant plaque volume of SVG lesions for all three modalities. Having gained an understanding of the accuracy of MDCT and MRI, we investigated the relationships of MDCT plaque volume and density with embolic debris captured by distal protection device during SVG intervention. We then undertook histological assessment of the debris utilizing semi-automated image analysis software. We quantified the various plaque components including red blood cells, thrombus, lipid, cholesterol clefts and fibrous tissue. Finally, we explored the relationship between the histological findings with plaque volume, density and amount of embolization which occurred. Our last original chapter investigates the utility of multi-weighted MRI to assess carotid plaque prior to stenting. We measured plaque volumes and characterized plaques as calcific, fibrotic or lipidic according to MRI findings. This information is then correlated to the amount of embolic debris captured by the distal protection device used during stenting. In comparison to invasive imaging modalities like intravascular ultrasound, research into plaque characterization by MDCT and MRI is just beginning. Almost all of the current studies have been on coronary artery plaques. This thesis breaks new ground by studying SVG plaques and demonstrating links between plaque volume, composition and embolization during intervention. It builds on our knowledge of these non-invasive modalities and help us define their future roles.
Download or read book Atherosclerosis Clinical Perspectives Through Imaging written by Allen J Taylor and published by Springer Science & Business Media. This book was released on 2012-11-27 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.
Download or read book Coronary Ct Angiography In The Quantitative Analysis Of Coronary Plaques written by Zhong-hua Sun and published by World Scientific. This book was released on 2018-02-26 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the author's work which includes significant developments of coronary CT angiography in the diagnosis of coronary plaques. The main contributions of the book lie in the following areas: both 2D and 3D analysis of coronary plaques with coronary CT angiography, diagnostic value of coronary CT angiography with use of different multislice CT scanners, quantitative analysis of coronary plaques in terms of lumen assessment, and bifurcation angle analysis, in particular, the diagnostic performance of coronary CT angiography in calcified plaques, and finally, hemodynamic analysis of plaques with regard to the effects of plaques on coronary blood flow, and CT-derived fractional flow reserve (FFRCT).
Download or read book Coronary Angiography written by Baskot Branislav and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the intervening 10 years tremendous advances in the field of cardiac computed tomography have occurred. We now can legitimately claim that computed tomography angiography (CTA) of the coronary arteries is available. In the evaluation of patients with suspected coronary artery disease (CAD), many guidelines today consider CTA an alternative to stress testing. The use of CTA in primary prevention patients is more controversial in considering diagnostic test interpretation in populations with a low prevalence to disease. However the nuclear technique most frequently used by cardiologists is myocardial perfusion imaging (MPI). The combination of a nuclear camera with CTA allows for the attainment of coronary anatomic, cardiac function and MPI from one piece of equipment. PET/SPECT cameras can now assess perfusion, function, and metabolism. Assessing cardiac viability is now fairly routine with these enhancements to cardiac imaging. This issue is full of important information that every cardiologist needs to now.
Download or read book CT Evaluation of Coronary Artery Disease written by Paolo Pavone and published by Springer Science & Business Media. This book was released on 2009-03-01 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases are the leading cause of death in Western countries. In non-fatal cases, they are associated with a decreased quality of life as well as a substantial economic burden to society. Most sudden cardiac events are related to the complications of a non-stenosing marginal plaque. For this reason, the ability to properly identify the atherosclerotic plaque with a rapid, non-invasive technique is of utmost clinical interest in therapeutic planning. Coronary CT angiography produces high-quality images of the coronary arteries, in addition to defining their location and the extent of the atherosclerotic involvement. Proper knowledge of the equipment, adequate preparation of the patient, and accurate evaluation of the images are essential to obtaining a consistent clinical diagnosis in every case. With its clear and concise presentation of CT imaging of the coronary arteries, this volume provides general practitioners and cardiologists with a basic understanding of the technique. For radiologists with no direct experience in cardiac imaging, the book serves as an important source of information on coronary pathophysiology and anatomy.
Download or read book Vascular Imaging of the Central Nervous System written by Joana Ramalho and published by John Wiley & Sons. This book was released on 2014-03-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book-length reference to thoroughly describe diagnostic and therapeutic advances in the development of vascular radiology over the last decade The last ten years has seen vascular imaging of the central nervous system (CNS) evolve from fairly crude, invasive procedures to more advanced imaging methods that are safer, faster, and more precise—with computed tomographic (CT) and magnetic resonance (MR) imaging methods playing a special role in these advances. Vascular Imaging of the Central Nervous System is the first full-length reference text that shows radiologists—especially neuroradiologists—how to optimize the use of the many techniques available in order to increase the sensitivity and specificity of vascular imaging, thereby improving the diagnosis and treatment of individual patients. Each chapter is formatted carefully and divided into two essential parts: The first part describes the physical principles underlying each imaging technique, along potential associated artifacts and pitfalls; the second part addresses clinical applications and novel applications of each method. With a strong focus on the clinical application of each modality or technique in CNS radiology, this book provides in-depth chapter coverage of: • Ultrasound Vascular Imaging (UVI) • Computed Tomography Angiography (CTA) • Magnetic Resonance Vascular imaging (MRV) • Digital subtraction angiography (DSA) • Brain perfusion techniques: CT and MRI • Plaque imaging • Intravascular imaging • Pediatric vascular imaging Along with numerous illustrations and case studies, Vascular Imaging of the Central Nervous System: Physical Principles, Clinical Applications, and Emerging Techniques is an important book for those faced with choosing from the wide range of choices available for clinical practice.
Download or read book Plaque Imaging written by Jasjit S. Suri and published by IOS Press. This book was released on 2005 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication starts of with a review of plaque imaging techniques, with an introduction of the segmentation techniques for plaque classification and quantification. Many aspects of plaque imaging techniques are presented in this publication, such as; medical image retrieval and database management, MRI techniques to differentiate stable versus high risk atherosclerosis, composition and morphology of atherosclerotic plaque, analysis of the soft tissue based on computer vision techniques, modelling of coronary artery biomechanics, Cardiac CT for the assessment of cardiovascular pathology with an emphasis on the detection of coronary atherosclerosis, technical and practical issues regarding coronary atherosclerotic plaque imaging by CT (focussing on coronary calcium imaging), feasibility of a non-invasive, in vivo determination of the IBS of arterial wall tissue, high resolution ultrasound images of carotid plaques, the problem of reliable features extraction and classification process and a discussion on advanced mathematical techniques to extract spectral information from the RF data to determine the plaque composition.
Download or read book The Vulnerable Plaque Second Edition written by Ron Waksman and published by CRC Press. This book was released on 2007-06-13 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since publication of the First Edition, advances in the diagnosis and prevention and treatment strategies of the vulnerable plaque have necessitated this greatly expanded second edition. With several new chapters covering mainly diagnostic and treatment options, The Handbook of the Vulnerable Plaque will remain the benchmark text for all interventional cardiologists treating vulnerable patients by providing the physician with comprehensive insight into the world of the vulnerable plaque.
Download or read book Diseases of the Chest Breast Heart and Vessels 2019 2022 written by Juerg Hodler and published by Springer. This book was released on 2019-02-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
Download or read book Assessment of Coronary Atherosclerosis Using Intravascular Ultrasound and Multidetector Computed Tomography written by Mark Eric Olszewski and published by . This book was released on 2005 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:
