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Book The Expression of Integrated Viral Genes in Adenovirus Transformed Cells

Download or read book The Expression of Integrated Viral Genes in Adenovirus Transformed Cells written by Marianne Wilhelmina van Maarschalkerweerd and published by . This book was released on 1981 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Adenoviruses

    Book Details:
  • Author : Harold S. Ginsberg
  • Publisher : Springer Science & Business Media
  • Release : 2013-03-08
  • ISBN : 1468479350
  • Pages : 620 pages

Download or read book The Adenoviruses written by Harold S. Ginsberg and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of adenoviruses naturally induced a new interest in viruses of the human upper respiratory tract since previously unknown viruses infecting this portion of the human body had not been identified in 20 years, and their unique characteristics stimulated investigations into the biochemical events essential for replication of animal viruses. Indeed, the field of molecular virology has evolved during the period since their dis covery, and adenoviruses have played a major role in this development. The exciting discoveries made with adenoviruses have had such a pro found effect on knowledge in basic virology, molecular biology, viral ge netics, human and animal infections, and cell transformation that this seemed a propitious time to have some of the major contributors review this field. This volume pays tribute to the late Wallace Rowe, Robert Huebner, and Maurice Hilleman whose initial discoveries of adenoviruses have tremendously enriched virology. Harold S. Ginsberg vii Contents Chapter 1 An Overview 1 Harold S. Ginsberg Chapter 2 The Architecture of Adenoviruses M. V. Nermut I. Introduction ................................... . 5 II. Chemical and Physical Properties ................... . 6 III. Virus Capsid: Composition and Organization .......... . 7 A. Hexon ..................................... . 10 B. Penton .................................... . 12 C. Other Virus Polypeptides Associated with the Capsid 13 D. Organization of the Capsid ..................... . 14 IV. Virus Core .................................... . 15 A. Evidence for the Core Shell ..................... . 17 B. Organization of the DNA-Protein Complex (Nucleoc- sid) ....................................... . 18 C. Tentative Model of the Adenovirus Nucleocapsid ... . 22 V. Model of the Adenovirion ......................... . 29 32 References .......................................... .

Book Adenovirus DNA

    Book Details:
  • Author : Walter Doerfler
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 1461322936
  • Pages : 464 pages

Download or read book Adenovirus DNA written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Molecular Biology of Adenoviruses 3

Download or read book The Molecular Biology of Adenoviruses 3 written by W. Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Holland Frei Cancer Medicine

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Book The Molecular Biology of Adenoviruses 2

Download or read book The Molecular Biology of Adenoviruses 2 written by W. Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Arrangement and Stability of Integrated Viral DNA In  I  Adenovirus Type 2 Transformed Cell Lines that Differ in Tumorigenic Potential and II  Simian Virus 40 Transformed Cell Lines which Induce Intracranial Hamster Tumors Exhibiting Different Invasiveness Potentials

Download or read book Arrangement and Stability of Integrated Viral DNA In I Adenovirus Type 2 Transformed Cell Lines that Differ in Tumorigenic Potential and II Simian Virus 40 Transformed Cell Lines which Induce Intracranial Hamster Tumors Exhibiting Different Invasiveness Potentials written by Gregory John Duigou and published by . This book was released on 1985 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Adenoviruses  Model and Vectors in Virus Host Interactions

Download or read book Adenoviruses Model and Vectors in Virus Host Interactions written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy.

Book Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12 transformed  transformed  hamster cells and methylation of the integrated viral DNA

Download or read book Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12 transformed transformed hamster cells and methylation of the integrated viral DNA written by Diane Jane Kühn and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12 transformed hamster cells and methylation of the integrated viral DNA

Download or read book Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12 transformed hamster cells and methylation of the integrated viral DNA written by Diane Jane Kühn-Sutter and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Molecular Biology of Adenoviruses I

Download or read book The Molecular Biology of Adenoviruses I written by W. Doerfler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: A puzzling epidemiological problem was the driving force behind the discovery of human adenoviruses by Wallace Rowe and his colleagues 30 years ago. The de velopment of a plaque assay for poliomyelitis virus in 1953 led us to the threshold of quantitative virology, and in the same year the double-helical structure of DNA was discovered and became a cornerstone of mo lecular biology. The potential of adenoviruses as research tools in the molecular and cellular biology of eukaryotic cells was recognized as early as the late 1950s and early 1960s by several investigators. Structural and biochemical stu dies dominated the early years. In 1962, some of the adenoviruses were the first human viruses shown to be oncogenic in experimental animals. Thus adenovirology offered the investigator the entire gamut of host cell interactions, productive and abortive, as well as trans formed and tumor cell systems. The possibilities that adenoviruses afforded for the study of the molecular biology and genetics of eukaryotic cells were fully rea lized in the late 1960s and the 1970s.

Book Adenoviruses  Model and Vectors in Virus Host Interactions

Download or read book Adenoviruses Model and Vectors in Virus Host Interactions written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens.

Book Molecular Biology of Adenoviruses

Download or read book Molecular Biology of Adenoviruses written by L. Philipson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: I. Introduction In his biography "Arrow in the Blue" the author Arthur Koestler suggests ironically that the fate of an individual may be predicted by examining the content of the newspapers at birth. Adenoviruses were discovered in 1953 (ROWE et al. , 1953; HILLEMAN and WERNER, 1954). At this time the Salk poliomyelitis vaccine was developed (SALK et al. , 1954) and in the same year the discovery of the double helical structure of DNA (WATSON and CRICK, 1953) and the plaque assay for one animal virus (DULBECCO and VOGT, 1953) was announced. Thus, this new group of viruses was born with great hopes for progress in molecular biology and for the control of animal virus infections. In the short interval be tween 1953 and 1956 the adenoviruses were discovered, methods for laboratory diagnosis and serotyping were established, the epidemiology was clarified and a highly effective vaccine was developed and approved (for a review see HILLE MAN, 1966). Succeeding years showed, however, that the vaccines were contami nated with the oncogenic SV 40 virus and that the adenoviruses themselves were tumorigenic. Since the discovery of adenoviruses animal virology was developed into a quantitative science offering explanation for viral functions at the molecular level. Precise biochemical tools to characterize the genome and its transcription products as well as the structural proteins of these viruses are now available.