Download or read book Applied RNA Bioscience written by Seiji Masuda and published by Springer. This book was released on 2018-04-10 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available. Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production. This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.

Download or read book Applied RNA Bioscience written by Seiji Masuda and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this book is to introduce up-to-date information on applications and practical use of RNA for agriculture, biotechnology and medicine. It provides unique ideas, tools, and methods in detail from a variety of scientific and technical disciplines. RNA science has progressed enormously in recent decades, and vast amounts of information on RNA functions and their regulatory mechanisms are becoming available. Such a progress opened the door to an age of practical application of RNA in many fields including agriculture, plant science, medical science, brewing and fermentation technology, and material production. This book inspires its readership and contributes to not only expansion in application of RNA but also to basic research.

Download or read book Molecular Biology of RNA written by David Elliott and published by Oxford University Press. This book was released on 2017-01-31 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

Download or read book Cartilage Tissue Engineering written by Martin J. Stoddart and published by Springer Nature. This book was released on 2022-11-10 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book brings together a collection of methodologies, from the most basic to the more complex, that provides researchers with a platform they can use to embark on a cartilage research career. To aid in the search for novel therapies for cartilage regeneration, this volume addresses 3D cartilage models, challenges associated with RNA and protein extraction, imaging, gene transfer, as well as stable differentiation and variations in cell phenotype from different tissue origins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Cartilage Tissue Engineering serves as an ideal guide for researchers working to advance the vital study of cartilage biology and repair.

Download or read book RNA Structure and Function written by Jan Barciszewski and published by Springer Nature. This book was released on 2023-12-05 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the current status of our understanding of RNA, a key biological molecule. The various RNAs covered are messenger RNA, ribosomal RNA, transfer RNA, noncoding RNAs, modified nucleosides, and RNA enzymes. The different chapters detail methods to investigate RNA structure and function, the chemistry of modified RNAs, and the latest advances in our understanding of the vast array of biological processes in which RNA is involved. RNA, in one form or another, touches almost everything in a cell. RNA has both structural and catalytic properties. RNA fulfills a broad range of functions. These molecules are no longer seen as passive elements transferring the genetic information from DNA into proteins but regulate the activity of genes during development, cellular differentiation, and changing environments. RNAs are involved in various aspects of cell physiology and disease development. Discoveries of RNA with unexpected diverse functions in healthy and diseased cells, such as the role of RNA as both the source and countermeasure to cancer or severe viral infection, stimulate new trends, passion, and solutions for molecular medicine. In this book, fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, how to determine RNA structure and how to apply RNA in treatment of diseases. This book is an essential resource for researches in academia and industry contributing to the development of new RNA therapeutics. The book is geared toward scientists from the graduate level on up and particularly appeals to active investigators in RNA biology, molecular biology, and biochemistry.

Download or read book RNA Biochemistry and Biotechnology written by Jan Barciszewski and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: RNA Biochemistry and Biotechnology describes various aspects of nucleic acid and protein structure, mainly RNA structure and proteins, interacting with specific RNA species. Papers deal with DNA protein interactions, telomerase, aminoacyl-tRNA synthetases, elongation factor Tu, DNA repair, RNA structure, NMR technology, RNA aptamer interaction of biological macromolecules with metal ions. Two papers deal with theoretical aspects of RNA structure production and computer modelling. Many papers describe the possibility of commercial application of RNA biotechnology. One article discusses the impact of direct democracy on basic science supporting biotechnology. Readership: Advanced graduate students, Ph.D. students and young scientists as well as specialists in the field.

Download or read book RNA Exosome written by Torben Heick Jensen and published by Springer Science & Business Media. This book was released on 2011-06-29 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diversity of RNAs inside living cells is amazing. We have known of the more “classic” RNA species: mRNA, tRNA, rRNA, snRNA and snoRNA for some time now, but in a steady stream new types of molecules are being described as it is becoming clear that most of the genomic information of cells ends up in RNA. To deal with the enormous load of resulting RNA processing and degradation reactions, cells need adequate and efficient molecular machines. The RNA exosome is arising as a major facilitator to this effect. Structural and functional data gathered over the last decade have illustrated the biochemical importance of this multimeric complex and its many co-factors, revealing its enormous regulatory power. By gathering some of the most prominent researchers in the exosome field, it is the aim of this volume to introduce this fascinating protein complex as well as to give a timely and rich account of its many functions. The exosome was discovered more than a decade ago by Phil Mitchell and David Tollervey by its ability to trim the 3’end of yeast, S. cerevisiae, 5. 8S rRNA. In a historic account they laid out the events surrounding this identification and the subsequent birth of the research field. In the chapter by Kurt Januszyk and Christopher Lima the structural organization of eukaryotic exosomes and their evolutionary counterparts in bacteria and archaea are discussed in large part through presentation of structures.

Download or read book Biology of RNA written by J. L. Sirlin and published by . This book was released on 1972 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular aspects of RNA: Functional aspects of RNA; Biological and evolutionary aspects of RNA.

Download or read book RNA Modifications written by Mary McMahon and published by . This book was released on 2021 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book describes some of the most recent advances and up-to-date methodologies to detect, quantify, analyze, and elucidate the biological function of different types of RNA modifications. Importantly, the methodologies and tools described herein can be applied to a wide variety of organisms and can be used to address biological and clinical questions. Beginning with a section on bioinformatics tools, the collection continues with sections on detecting RNA modifications using Nanopore direct RNA sequencing, next-generation sequencing approaches, qPCR- and molecular biology-based methods, mass spectrometry- and NMR-based methods, as well as approaches to assess kinetics, determinants, and functions of RNA modifications. Written for the highly successful Methods in Molecular Biology series style, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, RNA Modifications: Methods and Protocols serves as an ideal guide for those working directly in the fields of epitranscriptomics and post-transcriptional gene regulation, as well as for scientists and clinicians interested in bioinformatic tools to study RNA modifications and techniques to dissect their roles in physiology and disease. Chapter 20 is available open access under a CC BY 4.0 license.

Download or read book RNAi Based Pesticides written by Hailing Jin and published by Frontiers Media SA. This book was released on 2021-09-29 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Combining Simulations Theory and Experiments into Multiscale Models of Biological Events written by Fabio Trovato and published by Frontiers Media SA. This book was released on 2022-01-11 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Enhanced biological mechanism study drug discovery and individualized medicine with single cell multiomics data and integrative analysis written by Panwen Wang and published by Frontiers Media SA. This book was released on 2023-07-20 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Roles Of Non coding RNAs In Tumor Growth And Development written by Giovanni Blandino and published by Frontiers Media SA. This book was released on 2023-01-05 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gene Silencing by RNA Interference written by Muhammad Sohail and published by CRC Press. This book was released on 2004-08-27 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Maximizing the potential of RNA interference in functional genomics - as well as in the development of therapeutics - continues to be at the forefront of biomedical research. Unlike journal articles, Gene Silencing by RNA Interference: Technology and Application combines essential background to the RNAi field with practical techniques designed by r

Download or read book Research Methodology and Project Management in Biotechnology written by Simmi Kharb and published by Bentham Science Publishers. This book was released on 2023-12-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methodology and Project Management in Biotechnology is a vital resource addressing core concepts in the dynamic field of biotechnology. This comprehensive textbook focuses on research methodology, techniques, and project management, and provides essential knowledge for students and faculty in life sciences and allied disciplines. Key features of the book include learning objectives, self-assessments and exercises, and a simple presentation (using bullet points, tables, and figures) designed to assist comprehension and retention of key information. The book is split into 5 units with 12 focused chapters: Unit I: Molecular Biology Techniques Covers various techniques used in molecular biology, including nucleic acid isolation, DNA fragmentation, PCR, DNA sequencing, and more. Unit II: Scientific Communication and Literature Introduces the process of research writing. Unit III: Biotechnology Entrepreneurship and Marketing Covers the role of funding, intellectual property rights, and regulations. Unit IV: Genomics, Proteomics, and Bioinformatics Explores DNA sequencing strategies, gene expression analysis, and the role of bioinformatics in drug discovery. Unit V: Advanced Biotechnological Techniques Covers topics such as antisense technology, molecular cytogenetics, pharmacogenomics, next-generation DNA sequencing, and ethical considerations in science and technology. Unit VI: Medical Biotechnology Covers disease detection and diagnosis, genetic diseases, personalized medicine, nanotechnology, gene therapy, regenerative medicine, and the Human Genome Project. This textbook is suitable for courses aimed to enhance biotechnology project planning and execution skills and building a professional career path in biotechnology. Readership Students and faculty in life sciences and allied courses.

Download or read book Nucleic Acids Advances in Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic Acids—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about RNA. The editors have built Nucleic Acids—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about RNA in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Nucleic Acids—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book RNA Diseases in Humans From Fundamental Research to Therapeutic Applications written by Naoyuki Kataoka and published by Frontiers Media SA. This book was released on 2019-10-15 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic addresses the human diseases caused by a malfunction of the RNA metabolism. We aim at strengthening the link between fundamental research and therapeutic applications. In eukaryotes, RNA is transcribed from genomic DNA. RNA molecules undergo multiple post-transcriptional processes such as splicing, editing, modification, translation, and degradation. A defect, mis-regulation, or malfunction of these processes often results in diseases in humans, referred to as 'RNA diseases'. There is an increasing number of studies focused on RNA diseases, which are aimed at uncovering the fundamental molecular mechanisms at play in order to develop therapeutic approaches.