Download or read book Applications of Statistical Mechanics to Biological Macromolecules written by Nikolay V. Dokholyan and published by . This book was released on 1999 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Equilibria and Kinetics of Biological Macromolecules written by Prof. Jan Hermans and published by John Wiley & Sons. This book was released on 2013-10-22 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models. With its strong emphasis on molecular interactions, Equilibria and Kinetics of Biological Macromolecules offers new insights and perspectives on proteins and other macromolecules. The text features coverage of: Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries. With its classroom-tested pedagogical approach, Equilibria and Kinetics of Biological Macromolecules is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.

Download or read book Statistical Mechanics and Stability of Macromolecules written by Earl Prohofsky and published by Cambridge University Press. This book was released on 2005-07-14 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book develops a statistical mechanical analysis of the stability of biological macromolecules. The author's approach is valid both for the long time-scale needed for DNA bond disruption, and also for highly cooperative transitions needed to explain helix melting. Prohofsky develops a new theoretical approach for executing macromolecule calculations. In particular the author devises a method for describing chemical bond disruption in these large systems, which is then used to determine when the helix melts and how drugs can dissociate from the helix. The author finds melting temperatures to be in excellent agreement with experimental observations.

Download or read book Statistical Mechanics of Biological Macromolecules written by Arkady Leonidovich Kholodenko and published by . This book was released on 1982 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Mechanics with Applications to Physics and Chemistry written by Richard Chace Tolman and published by . This book was released on 1927 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Equilibrium and Nonequilibrium Statistical Mechanics of Biological Macromolecules written by Martin Schwarz and published by . This book was released on 1975 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Physics for Biological Matter written by Wokyung Sung and published by . This book was released on 2018 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers a broad range of topics in statistical physics, including statistical mechanics (equilibrium and non-equilibrium), soft matter and fluid physics, for applications to biological phenomena at both cellular and macromolecular levels. Typical statistical physics courses cover ideal gases (classical and quantum) and interacting units of simple structures. In contrast, even simple biological fluids are solutions of macromolecules, the structures of which are very complex. This book fills this wide gap by providing appropriate content as well as by explaining the theoretical method that typifies good modeling, namely, the method of coarse-grained descriptions that extract the most salient features emerging at mesoscopic scales. The major topics covered in this book include thermodynamics, equilibrium statistical mechanics, soft matter physics of polymers and membranes, non-equilibrium statistical physics covering stochastic processes, transport phenomena and hydrodynamics. Generic methods and theories are described with detailed derivations, followed by applications and examples in biology. By systematically and coherently covering the basic principles, this book helps the readers to build up their understanding of nonspecific concepts and theoretical methods, which they may be able to apply to a broader class of biological problems. While intended as a graduate level textbook, it can also address the interested senior level undergraduate. In addition, it is suitable for those involved in research on biological systems or soft matter based on physics, particularly on statistical physics.

Download or read book Statistical Physics for Biological Matter written by Wokyung Sung and published by Springer. This book was released on 2018-10-19 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to cover a broad range of topics in statistical physics, including statistical mechanics (equilibrium and non-equilibrium), soft matter and fluid physics, for applications to biological phenomena at both cellular and macromolecular levels. It is intended to be a graduate level textbook, but can also be addressed to the interested senior level undergraduate. The book is written also for those involved in research on biological systems or soft matter based on physics, particularly on statistical physics. Typical statistical physics courses cover ideal gases (classical and quantum) and interacting units of simple structures. In contrast, even simple biological fluids are solutions of macromolecules, the structures of which are very complex. The goal of this book to fill this wide gap by providing appropriate content as well as by explaining the theoretical method that typifies good modeling, namely, the method of coarse-grained descriptions that extract the most salient features emerging at mesoscopic scales. The major topics covered in this book include thermodynamics, equilibrium statistical mechanics, soft matter physics of polymers and membranes, non-equilibrium statistical physics covering stochastic processes, transport phenomena and hydrodynamics. Generic methods and theories are described with detailed derivations, followed by applications and examples in biology. The book aims to help the readers build, systematically and coherently through basic principles, their own understanding of nonspecific concepts and theoretical methods, which they may be able to apply to a broader class of biological problems.

Download or read book Molecular Driving Forces written by Ken Dill and published by Garland Science. This book was released on 2010-10-21 with total page 845 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Driving Forces, Second Edition E-book is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world. Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. The Second Edition includes two brand new chapters: (1) "Microscopic Dynamics" introduces single molecule experiments; and (2) "Molecular Machines" considers how nanoscale machines and engines work. "The Logic of Thermodynamics" has been expanded to its own chapter and now covers heat, work, processes, pathways, and cycles. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.

Download or read book Thermodynamics and Statistical Mechanics of Macromolecular Systems written by Michael Bachmann and published by . This book was released on 2014 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Modern Applications of Flory s statistical Mechanics of Chain Molecules written by Alan E. Tonelli and published by . This book was released on 2020-12 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Mechanics Protein Structure and Protein Substrate Interactions written by Sebastian Doniach and published by Springer. This book was released on 2013-06-19 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which makes it possible to isolate and clone specific molecules of interest in sufficient quantities to enable structural measurements. In addition, the ability to mutate a given amino acid sequence at will has led to a new branch of biochemistry in which quantitative measurements can be made assessing the influence of a given amino acid on the function of a biological molecule. A third factor, resulting from the exponential increase in computing power available to researchers, has been the emergence of a growing body of people who can take the structural data and use it to build atomic-scale models of biomolecules in order to try and simulate their motions in an aqueous environment, thus helping to provide answers to one of the most basic questions of molecular biology: the relation of structure to function.

Download or read book Quantum Statistical Mechanics in the Natural Sciences written by Stephan Mintz and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: leagues and, in many cases, students, of Professor Onsager. Professor Onsager, himself, has contributed a paper on Illife in early times" to the volume. Among the topics discussed are some interesting applications of low temperature experimental techniques to cardiology and astrophysics. We would like to express our particular appreciation to Mrs. Helga Billings and Miss Sara Lesser for their excellent typing of these Proceedings and to Mrs. Jacquelyn Zagursky, as well as to Mrs. Billings and Miss Lesser for their invaluable assistance with the details of the conference and the publication of these Proceedings. The Editors CONTENTS Section One BIOLOGY Life in the Early Days Lars Onsager. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 The Fluctuating Enzyme Giorgio Careri. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Diffusion Control in Biochemical Reactions Manfred Eigen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 Phase Transitions of Phospholipids Julian Sturtevant. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63 Theory and Density Measurements of the Lipid Bilayer Phase Transition John F. Nagle. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Stability of Helical Nucleic Acids Neville R. Kallenbach. . . . . . . . . . . . . . . . . . . . . . . . . . . 95 Thermodynamic Perspectives and the Origin of Life Sidney W. Fox. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 Section Two STATISTICAL MECHANICS High Frequency Dielectric Response in Dipolar Systems Roberto Lobo, John E. Robinson, Sergio Rodriguez. 143 ix x CONTENTS Exact Derivation of the Onsager Limiting Law Thomas J. Murphy 157 The Effect of Wall Charge on the Capillary Rise of Electrolytes Lars Onsager, Edmund Drauglis 167 Density of States of Topologically Disordered Amorphous Semiconductors Jill C. Bonner, J. F. Nagle 201 Irreversibility Willis E. Lamb, Jr. 213 Surface Specific Heat of Crystals.

Download or read book Statistical Mechanics of Biological Macromolecules written by Douglas Cole Poland and published by . This book was released on 1966 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Internal Motions in Biological Systems written by Giovanni Lipari and published by . This book was released on 1982 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Applications of Statistical Mechanics to Problems in Biology written by Francesco Alessandro Massucci and published by . This book was released on 2012 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a consequence of the impressive technological development of the last decades, our knowledge about many microscopic biological systems has grown exponentially. At present, for instance, the refinement of experimental techniques allows us to perform single molecule manipulation experiments, or to know exactly which proteins are codified by the genes. Unfortunately our predictive power has not improved accordingly and many of the phenomena involved in those experiments remain unexplained within a more general perspective. For example, the force-extension relations of a lambda-phage DNA are quite well-known, but we cannot possibly use this information to predict how a different molecule will respond to the same experiment. This is due to the lack of solid tools to relate the experimental observations to the physical nature of the molecule (and hence to its mechanical properties). Similarly, after successfully sequencing the genome of several living beings, we know now the topology of their metabolic networks. This knowledge, however, does not allow us to speculate how their metabolism will operate at a systems level and moreover how this performance will vary according to a change of external conditions or to a gene knock out. -- In this thesis we try to give a general solution to problems of this kind, applying the same tools of statistical mechanics that have proven to be successful in the field of complex systems. We focus in particular on two topics, polymer stretching and metabolic networks. -- In the context of polymer stretching we solve a phenomenological model using the cavity method, a standard way to compute the marginal probability distributions of the dynamical variables in statistical mechanics. We successfully fit the model to a set of experimental measurements, being able to relate the observations to the physical properties of the molecule.

Download or read book A Guide to Monte Carlo Simulations in Statistical Physics written by David P. Landau and published by Cambridge University Press. This book was released on 2009-09-10 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dealing with all aspects of Monte Carlo simulation of complex physical systems encountered in condensed-matter physics and statistical mechanics, this book provides an introduction to computer simulations in physics. This edition now contains material describing powerful new algorithms that have appeared since the previous edition was published, and highlights recent technical advances and key applications that these algorithms now make possible. Updates also include several new sections and a chapter on the use of Monte Carlo simulations of biological molecules. Throughout the book there are many applications, examples, recipes, case studies, and exercises to help the reader understand the material. It is ideal for graduate students and researchers, both in academia and industry, who want to learn techniques that have become a third tool of physical science, complementing experiment and analytical theory.