Download or read book Applications of Pulsed Field Gradient Techniques and Slice Selective Methods in NMR Spectroscopy written by Kaitlyn Doolittle and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Slice selection NMR spectroscopy is a method that enables the chemical analysis of specific, selected regions of an NMR sample along the z-axis. This type of NMR spectroscopy has applications in metabolomics, kinetics, extractions analyses, and more. The focus of this work is the development of a novel slice selection experiment, called the one-shot double-slice experiment. This experiment enables the simultaneous analysis of two different regions within an NMR tube, with the ability to differentiate between the selected regions, due to the signals from each region being of opposite phase in the resulting NMR spectrum. Slice selection NMR is possible through the combination of pulsed field gradients and shaped pulses. In order to develop this methodology and novel experiment, it was first necessary to develop a deep understanding of those two fundamental components. Pulsed field gradients were investigated through diffusion NMR spectroscopy and one-dimensional NMR imaging. The diffusion experiments were conducted to determine the self-diffusion coefficients of surfactant at various concentrations, in order to further define the system beyond the critical micelle concentration (at which point surface tension no longer can provide insight as to changes in the system). The one-dimensional gradient imaging experiments were employed to determine the location of the receiver coil with respect to the interface of biphasic NMR samples, in order to optimize biphasic sample preparation. Biphasic samples of model compounds were then used to test out classic slice selection NMR experiments, and to test out the novel one-shot double-slice one-dimensional experiment and the two-dimensional TOCSY version that were developed through this work. Once the model compound biphasic sample experiments were proven successful, the experiments were expanded to more complex biphasic samples that are more representative of real-life samples. The samples used to test these experiments were in-tube extractions of tea leaves and of hot and cold brewed coffees. The result of this research is a novel experiment that provides information about two different regions (or phases, in the case of biphasic samples) simultaneously in a single experiment. This experiment was proven to be robust and easy to implement, and it presents new opportunities for the field of slice selection NMR spectroscopy.
Download or read book Magnetic Resonance Microscopy written by Bernhard Blümich and published by . This book was released on 1992 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book NMR in the Life Sciences written by E. Morton Bradbury and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Magnetic Resonance Spectroscopy written by E.B. Cady and published by Springer. This book was released on 1990-07-31 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobody can know everything. For the successful application of techniques based on nuclear magnetic resonance to clinical problems, it is a vital necessity that individuals with widely different skills should learn a little of each others' trades by co-operation and communication. Ernest Cady has long proved himself a master of these arts to his colleagues at University College London, and by writing this excellent book he extends his experience to a wide circle of readers. Although the nuclear magnetic resonance (NMR) phenomenon had been predicted theoretically (and to some degree demonstrated experimentally) appreciably earlier, it required the advances in electronics that took place during World War II to turn NMR into a practical technique, as demonstrated independently in 1946 by Bloch and Purcell. Since then, NMR has been used extensively and increasingly by chemists and physicists. In the 1970s the first applications of NMR to animal organs yielded important advances in our knowledge of the biochemical and physiological processes as they occur in genuinely intact tissues. They showed incidentally that some conventional techniques introduce significant artifacts.
Download or read book NMR in Medicine written by American Association of Physicists in Medicine. Summer School and published by American Institute of Physics. This book was released on 1986 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, we have witnessed a dramatic acceleration in the application of magnetic resonance techniques within the medical sciences. Following the original experimental demonstration of the NMR phenomenon by Bloch and Purcell in 1946, emphasis was directed toward the study of physical materials: however, in the 1950's and 1960's, research was reported on the use of NMR to investigate the properties of biological materials including cell systems, excised muscle tissue and certain in vivo models. This book fully discusses this important topic.
Download or read book NMR Imaging in Biomedicine written by P Mansfield and published by Elsevier. This book was released on 1982-04-28 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR Imaging in Biomedicine: Advances in Magnetic Resonance discusses significant advances in NMR imaging and its application to the field of biomedicine. This book is organized into 10 chapters that cover the classification, methods, imaging regimes, and the potential use of NMR imaging in medicine. After discussing the basic theoretical ideas of NMR and its application to NMR imaging, this book presents mathematical analyses of the various NMR techniques, focusing primarily on the comparison in terms of imaging speed and data-acquisition rate. It also covers a number of practical ranges or imaging regimes in terms of sensitivity, sample size, and operating frequency. Significant topics on potential application of NMR imaging in medicine, apparatus requirements in the instrumentation of NMR imaging machines, and the principles of biomagnetic effects are discussed in other chapters. The considered biomagnetic effects are categorized into three main groups: the effects of static magnetic fields, the effects of relatively slow varying time-dependent fields, and radio-frequency magnetic fields. This book is of great value to radiologists, medical physicists, neuroradiologists, anatomists, physiologists, and postgraduate students of NMR imaging.
Download or read book NMR Spectroscopy Techniques written by Martha Bruch and published by CRC Press. This book was released on 1996-03-05 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work elucidates the power of modern nuclear magnetic resonance (NMR) techniques to solve a wide range of practical problems that arise in both academic and industrial settings. This edition provides current information regarding the implementation and interpretation of NMR experiments, and contains material on: three- and four-dimensional NMR;
Download or read book Applications of NMR Spectroscopy written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-11-22 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The fifth volume of the series features several reviews focusing on NMR spectroscopic techniques for identifying natural and synthetic compounds (polymer and peptide characterization, GABA in tinnitus affected mice), medical diagnosis and therapy (gliomas) and food analysis. The spectroscopic methods highlighted in this volume include high resolution proton magnetic resonance spectroscopy and solid state NMR.
Download or read book Solid State NMR I Methods written by B. Blümich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. A.-R. Grimmer, Berlin, FRG; B. Bl}mich, Aachen, FRG: Introduction to Solid-State NMR 2. F. Laupretre, Paris, France: High-Resolution 13C NMRInvestigations of Local Dynamics in Bulk Polymers at Temperatures Below andAbove the Glass-Transition Temperature 3. D. Raftery, Philadelphia, PA;B.F. Chmelka, Santa Barbara, CA: Xenon NMR Spectroscopy 4. G. Fleischer, Leipzig, FRG; F. Fujara, Mainz, FRG: NMR as a Generalized Incoherent Scattering Experiment 5. P. Bl}mler, B. Bl}mich, Mainz, FRG: NMR Imaging of Solids.
Download or read book In vivo Magnetic Resonance Spectroscopy Probeheads and radiofrequency pulses spectrum analysis written by Markus Rudin and published by Springer. This book was released on 1992 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ionic Liquid Crystals written by Giacomo Saielli and published by MDPI. This book was released on 2019-06-24 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book we have collected a series of state-of-the art papers written by specialists in the field of ionic liquid crystals (ILCs) to address key questions concerning the synthesis, properties, and applications of ILCs. New compounds exhibiting ionic liquid crystalline phases are presented, both of calamitic as well as discotic type. Their dynamic and structural properties have been investigated with a series of experimental techniques including differential scanning calorimetry, polarized optical spectroscopy, X-ray scattering, and nuclear magnetic resonance, impedance spectroscopy to mention but a few. Moreover, computer simulations using both fully atomistic and highly coarse-grained force fields have been presented, offering an invaluable microscopic view of the structure and dynamics of these fascinating materials.
Download or read book High Resolution NMR Techniques in Organic Chemistry written by Timothy D.W. Claridge and published by Newnes. This book was released on 2009 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nuclear Magnetic Resonance (NMR) Spectroscopy remains the foremost analytical technique for the structure elucidation of organic molecules and an indispensable tool for the synthetic, medicinal and natural product chemist. New techniques continue to emerge and the application of NMR methods continues to expand. High-Resolution NMR Techniques in Organic Chemistry is designed for use in academic and industrial NMR facilities, as a text for graduate-level NMR courses, and as an accessible reference for the chemist's or spectroscopist's desk."--BOOK JACKET.
Download or read book MRI from Picture to Proton written by Donald W. McRobbie and published by Cambridge University Press. This book was released on 2017-04-13 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.
Download or read book Nuclear Magnetic Resonance written by G A Webb and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.
Download or read book Nuclear Magnetic Resonance Spectroscopy in the Study of Neoplastic Tissue written by Raffaella Tosi and published by Nova Publishers. This book was released on 2005 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vivo NMR Spectroscopy written by Robin A. de Graaf and published by John Wiley & Sons. This book was released on 2013-03-21 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a unique book in the field of in vivo NMR covering in detail the technical and biophysical aspects of the technique. The contents of the book are appropriate to both beginners and experienced users of in vivo NMR spectroscopy. The new edition is focussed on bringing the reader practical insights and advice, but is also geared towards use as a study aid and in NMR courses. Recent advances in NMR spectroscopy, like high field NMR, hyperpolarized NMR and new localization and editing techniques have been included. An extensive and updated treatment of radiofrequency pulses is given, together with several tables and recipes for their generation. Solutions to the exercises within this text can be found here
Download or read book Shaped Selective Pulses and Their Applications in Nuclear Magnetic Resonance Spectroscopy and Imaging written by Lyndon Emsley and published by . This book was released on 1991 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:
