Download or read book Applications of Genomics and Proteomics for Analysis of Bacterial Biological Warfare Agents written by Vito G. DelVecchio and published by IOS Press. This book was released on 2003 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicogenomics and Proteomics written by James J. Valdes and published by IOS Press. This book was released on 2004 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The field of toxicology has developed a well-characterized set of techniques to assess the behavioral and histopathological consequences of exposure to environmental insults using a number of animal models. These techniques are suitable for determining crude endpoints of exposure such as death, but are not optimal for assessing the more subtle effects of very low level or multi-agent chemical exposures, nor do they offer mechanistic explanations at the molecular level. This book is designed to have a mix of chapters devoted to classical toxicology followed by those focused more on the emerging techniques of toxicogenomics and proteomics. In this way, the relevance of new technologies such as gene arrays to classical toxicologic problems is made evident. Finally, because the worst of the world's toxicology problems reside in developing nations while the latest technical developments are occurring in the industrial nations, we sought to provide a balance of both scientific and geographical perspectives from researchers engaged in toxicology and public health research.
Download or read book Emerging Biological Threat written by Akbar S. Khan and published by IOS Press. This book was released on 2005 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Historical Dictionary of Nuclear Biological and Chemical Warfare written by Benjamin C. Garrett and published by Rowman & Littlefield. This book was released on 2017-08-25 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: The history of biological weapons (BW), chemical weapons (CW), and nuclear weapons is complicated. It can be disturbing, tragic, and occasionally encouraging. It is rarely amusing, although the names selected for certain weapons suggest a casualness toward the consequences of their use: Atomic Annie, Blue Peacock, Dew of Death, Fat Man, Flying cow, George, Gilda, Helen of Bikini, Hurricane, Katie, Little Boy, Lulu, Mike, Red Beard, Sewer Pipe, Squirt. Use of BW and CW in warfare has produced mixed results in terms of effecting the outcome of a battle or campaign; despite this mixed record, both weapon types have attracted intense interest and strong advocacy for further use. The sole experience with use of nuclear weapons in warfare is viewed as hastening surrender by Japan, created competition among nations to develop more such weapons, and influenced efforts to ban any use or even stockpiling of such weapons. Each of these three weapon types has its own peculiar history, as recounted in this dictionary. This second edition of Historical Dictionary of Nuclear, Biological and Chemical Warfare contains a chronology, an introduction, and an extensive bibliography. The dictionary section has over 700 cross-referenced entries onterms related to NBC warfare, ranging from basic descriptions of substances used to details on incidents and episodes where NBC weapons were used, historical events, persons important to NBC warfare, countries where such weapons have been developed or used, and international treaties and treaty-related organizations.
Download or read book The A to Z of Nuclear Biological and Chemical Warfare written by Benjamin C. Garrett and published by Scarecrow Press. This book was released on 2009-09-16 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human experience with nuclear, biological, and chemical (NBC) warfare has been limited, especially in comparison to conventional forms of warfare. Our experience with nuclear warfare is confined to a period of less than one week during the end of World War II, when the United States successfully used two nuclear weapons against targets in Japan. The course of biological warfare and modern use of biological weapons are difficult to track owing to the difficulty of differentiating deliberate use from natural outbreaks. However, the keen potential of biological weapons in acts of terror was shown in the mass disruption caused in the fall 2001 experience in the U.S. with the release of anthrax through the American postal system. Chemical weapons have been used in a handful of conflicts since their introduction to modern warfare during World War I, most recently during the Iran-Iraq War during the 1980s. Despite this limited experience, NBC warfare continues to exert a certain fascination among states. The A to Z of Nuclear, Biological, and Chemical Warfare covers the development and use of NBC weapons as well as efforts to limit or control the use of these weapons through a chronology, a bibliography, an introductory essay, and dictionary entries. Over 500 cross-referenced dictionary entries provide a unique selection of terms related to NBC warfare, ranging from basic descriptions of substances used in NBC warfare to details on incidents and episodes where NBC weapons were used. Entries are structured around historical events, persons important to NBC warfare, countries where such weapons have been developed or used, and international treaties and treaty-related organizations.
Download or read book Opportunities in Biotechnology for Future Army Applications written by National Research Council and published by National Academies Press. This book was released on 2001-07-11 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
Download or read book Brucella Molecular Cell Biol written by Ignacio Lopez-Goni and published by Taylor & Francis. This book was released on 2005-11-08 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.
Download or read book Review of the Department of Energy s Genomics GTL Program written by National Research Council and published by National Academies Press. This book was released on 2006-04-19 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.
Download or read book Globalization Biosecurity and the Future of the Life Sciences written by National Research Council and published by National Academies Press. This book was released on 2006-06-07 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.
Download or read book Microarray Detection and Characterization of Bacterial Foodborne Pathogens written by Guillermo López-Campos and published by Springer Science & Business Media. This book was released on 2012-03-12 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of recent advances on the use of DNA microarray for diagnosing foodborne pathogens. Rapid detection and characterization of foodborne pathogens is critical for food safety. Many relevant technologies have been intensively developed to date. DNA microarray technology offers a new way to food safety involving pathogen detection and characterization. DNA microarray can be used for detection and characterization of pathogens by analyzing hybridization patterns between capture probes and nucleic acids isolated from food samples or bacteria. It allows more rapid, accurate, and cost-effective detection of pathogens compared with traditional approaches of cultivation or immuno-assays. The application of DNA microarrays to different foodborne bacteria, such as Campylobacter, Salmonella, Listeria monocytogenes, or Shiga toxin producing Escherichia coli, will improve their rapid identification and characterization of their genetic traits (e.g., antimicrobial resistance, virulence). As bacterial foodborne diseases are posing more serious threats to public healthcare, development of rapid and accurate methods for pathogen detection and characterization is critical to their proper control at the earliest time.
Download or read book Microbial Proteomics written by Ian Humphery-Smith and published by Wiley-Interscience. This book was released on 2006-08-11 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover important lessons learned about whole organism biology via microbial proteomics This text provides an exhaustive analysis and presentation of current research in the field of microbial proteomics, with an emphasis on new developments and applications and future directions in research. The editors and authors show how and why the relative simplicity of microbes has made them attractive targets for extensive experimental manipulation in a quest for both improved disease prevention and treatment and an improved understanding of whole organism functional biology. In particular, the text demonstrates how microbial proteomic analyses can aid in drug discovery, including identification of new targets, novel diagnostic markers, and lead optimization. Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent and thorough approach throughout. Methods, technologies, and tools associated with the most promising approaches are stressed. Key topics covered include: Microbial pathogenesis at the proteome level Whole cell modeling Structural proteomics and computational analysis Biomolecular interactions Physiological proteomics Metabolic reconstruction using proteomics data While presenting the practical utility of proteomics data, the text is also clear on the field's current limitations, pointing to areas where further investigation is needed. Offering a state-of-the-art perspective from internationally recognized experts, this text is ideally suited for researchers and students across the gamut of genomic sciences, including biochemistry, microbiology, molecular biology, genetics, biomedical and pharmaceutical sciences, biotechnology, and veterinary science.
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Download or read book Biotechnology Research in an Age of Terrorism written by National Research Council and published by National Academies Press. This book was released on 2004-03-02 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.
Download or read book Bio Inspired Innovation and National Security written by National Defense University and published by NDU Press. This book was released on 2010-10 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the vital importance of the emerging area of biotechnology and its role in defense planning and policymaking, no definitive book has been written on the topic for the defense policymaker, the military student, and the private-sector bioscientist interested in the "emerging opportunities market" of national security. This edited volume is intended to help close this gap and provide the necessary backdrop for thinking strategically about biology in defense planning and policymaking. This volume is about applications of the biological sciences, here called "biologically inspired innovations," to the military. Rather than treating biology as a series of threats to be dealt with, such innovations generally approach the biological sciences as a set of opportunities for the military to gain strategic advantage over adversaries. These opportunities range from looking at everything from genes to brains, from enhancing human performance to creating renewable energy, from sensing the environment around us to harnessing its power.
Download or read book Plague Wars written by Tom Mangold and published by Macmillan. This book was released on 2001-04-17 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winter 2001
Download or read book Metagenomics Techniques Applications Challenges and Opportunities written by Reena Singh Chopra and published by Springer Nature. This book was released on 2020-09-08 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various areas of research in metagenomics and their potential applications in medicine, the environment and biotechnology. The book presents the recent advances in theoretical, methodological and applied aspects of metagenomics and highlights their applications in the fields of environmental microbial forensics, bioremediation, drug-discovery and agriculture. In addition, the book discusses various metagenomics approaches used for understanding the microbial physiology and biochemistry. Lastly the book describes a range of bioinformatics tools and computational methods for metagenomics analysis as well as the functional diversity and dynamics of microbial communities colonizing the human skin.
Download or read book Book Review Index written by and published by . This book was released on 2005 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every 3rd issue is a quarterly cumulation.
