Download or read book Application of Electron Paramagnetic Resonance Spectroscopy to Examine Free Radicals in Melanin Polymers and the Human Melanoma Malignum Cells written by Barbara Pilawa and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The studies of free radicals in melanin and the human melanoma malignum cells by an X-band (9.3 GHz) electron paramagnetic resonance (EPR) spectroscopy were presented. The original results were compared with those published earlier. The aim of this work was application of the advanced spectral analysis to determine free radical properties in melanin biopolymers obtained from different melanotic tumor cells and free radicals existing in the human melanoma cells. Magnetic spin-lattice interactions in melanin samples were tested. The evolution of lineshape of tumor cells with increasing of microwave power was determined to confirm their complex free radical system. The useful shape parameters were proposed. The shape of melanotic tumor cells was analyzed. EPR spectra of free radicals in the melanin isolated from different tumor cells measured in the wide range of microwave power were analyzed. The melanins were obtained from the control tumor cells and the cells cultured with the several antitumor substances. The usefulness of the electron paramagnetic resonance spectroscopy was confirmed.

Download or read book Melanin written by Miroslav Blumenberg and published by BoD – Books on Demand. This book was released on 2017-03-01 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The word melanin refers to dark natural pigments produced by the oxidative degradation of tyrosine, catalyzed by tyrosinase, and polymerized into insoluble granular substance. The main function of melanin is to protect from harmful agents, primarily UV radiation, but also from oxidation, heavy metals, etc. In this volume, chapters deal with production of melanin in human oral mucosa (Liviu et al.), the regulation of melanin action (Cecile et al.), production and potential technological application of fungal melanins (Pombiero-Sponchiado et al.) and an innovative method for measuring melanin in various samples (Zdybel et al.). In conclusion, this volume presents various biological and industrial aspects of melanin production, uses and analysis.

Download or read book Application of Electron Paramagnetic Resonance Spectroscopy to the Study of Surface Defects and Adsorbed Molecules written by Jack H. Lunsford and published by . This book was released on 1966 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Macrofungi written by Kandikere R. Sridhar and published by CRC Press. This book was released on 2021-08-31 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Large scale cultivation of macrofungi is possible with fermentation, using easily accessible lignocellulosic agricultural residues applying economical methods to generate substantial biomass, food and biofuels. Bioconversion of lignocellulosic wastes by macrofungi generates value-added fungal nutritional biomass for humans and livestock. Besides commercial cultivation techniques, other topics covered in Advances in Macrofungi: Industrial Avenues and Prospects include: the healing potential of mushrooms, industrial opportunities, mycelium-based products, forest wild mushrooms and industrial applications of white rot fungi. This book reviews the industrial applications and uses of macrofungi. It encourages students and researchers to explore non-conventional sources of nutrition as well as bioactive metabolites to serve as nutraceuticals. It emphasizes the potential of macrofungi as a source of bioactive compounds to remedy human lifestyle diseases especially cancers and cardiovascular ailments along with immunostimulation potential by Cordyceps. This book emphasizes the role of on mushrooms as a source of cosmeceuticals, flavors, essence, scents and perfumes.

Download or read book Lipid derived Free Radical Production written by James A. North and published by . This book was released on 1993 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Study of Free Radicals by Electron Spin Resonance Spectroscopy written by W. T. Dixon and published by . This book was released on 1963 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Analysis of Free Radical Characteristics in Biological Systems Based on EPR Spectroscopy Employing Blind Source Separation Techniques written by Jiyun Ren and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Analysis of Free Radical Characteristics in Biological Systems Based on EPR Spectroscopy, Employing Blind Source Separation Techniques" by Jiyun, Ren, 任紀韞, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled Analysis of Free Radical Characteristics in Biological Systems Based on EPR Spectroscopy, Employing Blind Source Separation Techniques Submitted by Ren Jiyun for the degree of Doctor of Philosophy at The University of Hong Kong in June 2006 Free radicals, such as nitric oxide (NO), are highly reactive molecules that have been implicated critical in many physiological and pathophysiological pathways. Electron paramagnetic resonance (EPR) is recognized as a direct and reliable technique to measure a free radical, but the precise measurement of a free radial is still difficult to achieve. This thesis is therefore focused on the following two subjects. The first objective of the study is to find a proper method that can accurately separate the 'pure' components from mixed EPR spectra, as EPR spectrum of a free radical is often superimposed by overlapping spectra of other species. Two blind source separation (BSS) techniques, one based on independent component analysis (ICA), and the other based on sparse component analysis (SCA), were for the first time applied to EPR spectroscopy analysis. The studies, on both computer simulated free radical spectra and biologically obtained signals, show that both BSS techniques could give good separation provided that the source component spectra lines are not very broad and there are prominent non-overlapping peaks. The implementation of this method is simple, automatic, efficient, and does not require the component spectra to be known in advance. The novel method demonstrated a big improvement to the traditional means of manual work or with more sophisticated biomedical experiments. Moreover, compared to the automatic PCA and self-modeling techniques which have previously been used to separate complex EPR spectra, this study confirms that the two BSS techniques are more accurate, robust to noise, and simpler to implement in the cases of three and even more components. Within the two BSS approaches, the SCA approach, which is novelly developed exploiting the sparse property of signals, achieves even more accurate results. With the help of BSS techniques to extract the pure NO signal from the measured mixture signal, the second objective in the present study is to investigate experimentally the NO radical level which helps interpret the possible actions and mechanisms of NO during renal ischemia-reperfusion (I/R) of rats. When EPR is used to detect NO production, the two NO spin-trapping methods, "internal" hemoglobin trapping and "external" DETC-Fe trapping, result in two NO spin adducts, namely 2+ DETC -Fe -NO and HbNO. This thesis presents a novel comparison study on the properties of the two spin-trapping methods. Renal I/R model on rats were established through occluding the left renal artery for 30 min or 60 min. Animal experiments show that the external DETC-Fe trapping method is more sensitive, but 2+ DETC -Fe -NO in kidney would quickly decompose, thus can only be used for short-term I/R injury study; whereas the internal hemoglobin trapping is not so sensitive to small amount of NO, but more stable and tend to accumulate in blood, hence suitable for long-term in vivo I/R injury study. This property allows a novel dynamic monitoring of NO level (indicated by internal spin trap adduct HbNO) during renal I/R with X-band E

Download or read book Application of Electron Paramagnetic Resonance Spectroscopy to the Study of Surface Defects and Adsorbed Molecules written by Jack H. Lunsford and published by . This book was released on 1966 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Electron Paramagnetic Resonance EPR Study of Free Radicals in Irradiated Zinc Poly Methacrylate written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Melanins and Melanogenesis written by Giuseppe Prota and published by Academic Press. This book was released on 2012-12-02 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of melanin pigmentation, providing a concise, comprehensive picture of new knowledge gained at the frontiers of research. It draws heavily on the author's 30-year activity in the field and his continuing work with specialists of widely diverse disciplines. The core of the volume deals with the structure, physicochemical properties, and biosynthesis of the major classes of melanin pigments, including neuromelanins. Further discussions include the biology of the various types of pigment-producing cells, the structure and mode of action of tyrosinase, and the chemistry of urinary melanogens and their biomedical applications as metabolic markers of melanocyte activity, especially for the follow-up of malignant melanoma. Finally, the volume considers progress in the photobiology and photochemistry of melanins, with special emphasis on the controversial role of these pigments in skin photoprotection. Melanins and Melanogenesis is ideally suited as a basic guide for newcomers, and a handy source of specific information for practitioners in academic, medical, and industrial settings.

Download or read book The Pigmentary System written by James J. Nordlund and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1966 with total page 1636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Foundations of Modern EPR written by Gareth R. Eaton and published by World Scientific. This book was released on 1998 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception 50 years ago, electron paramagnetic resonance (EPR, also called ESR or EMR) has become a major tool in diverse fields ranging from biology and chemistry to solid state physics and materials science. This important book includes personal descriptions of early experiments by pioneers who laid the foundations for the field, perspectives on the state of the art, and glimpses of future opportunities. It presents a broad view of the foundations of EPR and its applications, and will therefore appeal to scientists in many fields. Even the expert will find here history not previously recorded and provocative views of future directions.

Download or read book The Complete book on Natural Dyes Pigments written by NIIR Board of Consultants & Engineers and published by ASIA PACIFIC BUSINESS PRESS Inc.. This book was released on 2005-10-04 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural dyes are dyes or colorants derived from plants, invertebrates, or minerals. The majority of natural dyes are vegetable dyes from plant sources. Dyeing is the process of imparting colors to a textile material. Different classes of dyes are used for different types of fiber and at different stages of the textile production process, from loose fibers through yarn and cloth to completed garments. There are technologies that manufacture the pigments for plastics, rubber and cosmetics. Therefore; dyes and pigments have a vast area of applications and have a huge demand in industry. Contrary to popular opinion, natural dyes are often neither safer nor more ecologically sound than synthetic dyes. They are less permanent, more difficult to apply, wash out more easily, and often involve the use of highly toxic mordant. Of course, the colour possibilities are far more limited; the color of any natural dye may be easily copied by mixing synthetic dyes, but many other colors are not easily obtained with natural dyes. However, some mordant are not very toxic, and the idea of natural dyestuffs is aesthetically pleasing. Applying natural dyes in your fabric production using enzymes will reduce your production cost and improve control. There are various kind of natural dyes; quinonoid dyes, cyanine dyes, azo dyes, biflvonyl dyes, omochromes, anthraquinone, coprosma gesus etc. The use of natural dyes in cloth making can be seen as a necessary luxury to trigger off a change in habits. Dyes which stand out for their beauty and ecological attributes would never be employed on just any material but on noble fabrics such as wool, silk, linen or cotton, made to last more than one season. Market value will benefit from consumer preferences for environmentally friendly products, which will support consumption of high performance dyes and organic pigments. This book basically deals with the use of carotenoids as food colours , bianthraquinones and related compounds, intermediate degradation products of biflavonyls, dyestuffs containing nuclear sulphonic and carboxylic acid groups, quinonoid dyes, cyanine dyes, optical whitening agents, natural dyes for food, stability of natural colourants in foods effect of additives, pyrimidine pigments, the total synthesis of the polyene pigments, red pigment from geniposidic acid and amino compound, effect of acid and amine on the formation of red pigment from geniposidic acid, effect of the substituted position of amino group and chain length of amino compound etc. Due to pollution problems in synthetic dyes and pigments industry, the whole world is shifting towards the manufacturing of natural dyes and pigments. The present book contains techniques of producing different natural dyes and pigments, which has huge demand in domestic as well as in foreign market. It is hoped that entrepreneurs, technocrats, existing units, institutional libraries will find this book very useful. 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Download or read book Melanins and Melanosomes written by Jan Borovansky and published by John Wiley & Sons. This book was released on 2011-10-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The surface pigmentation of vertebrates is controlled by specialized cells able to synthesize a variety of pigments collectively known as melanins. Recent research has shown that melanins are produced not only in the skin but also in many other sites such as the eye, inner ear, muscles, etc., - where they are engaged in some unanticipated roles. The details of the synthetic pathway, the complexities of its regulation and biological significance that have been unravelled in recent research comprise a fascinating story and are of key importance in understanding the nature of diseases, including malignant melanoma one of the most rapidly spreading cancers.

Download or read book Quantitative EPR written by Gareth R. Eaton and published by Springer Science & Business Media. This book was released on 2010-04-10 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a growing need in both industrial and academic research to obtain accurate quantitative results from continuous wave (CW) electron paramagnetic resonance (EPR) experiments. This book describes various sample-related, instrument-related and software-related aspects of obtaining quantitative results from EPR expe- ments. Some speci?c items to be discussed include: selection of a reference standard, resonator considerations (Q, B ,B ), power saturation, sample position- 1 m ing, and ?nally, the blending of all the factors together to provide a calculation model for obtaining an accurate spin concentration of a sample. This book might, at ?rst glance, appear to be a step back from some of the more advanced pulsed methods discussed in recent EPR texts, but actually quantitative “routine CW EPR” is a challenging technique, and requires a thorough understa- ing of the spectrometer and the spin system. Quantitation of CW EPR can be subdivided into two main categories: (1) intensity and (2) magnetic ?eld/mic- wave frequency measurement. Intensity is important for spin counting. Both re- tive intensity quantitation of EPR samples and their absolute spin concentration of samples are often of interest. This information is important for kinetics, mechanism elucidation, and commercial applications where EPR serves as a detection system for free radicals produced in an industrial process. It is also important for the study of magnetic properties. Magnetic ?eld/microwave frequency is important for g and nuclear hyper?ne coupling measurements that re?ect the electronic structure of the radicals or metal ions.

Download or read book Recent Advances in the Biology Therapy and Management of Melanoma written by Lester Davids and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.