Download or read book Antioxidants Exercise and Brain Function written by Akram Sidhu and published by . This book was released on 2016 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is associated with a decline in psychomotor and cognitive function. Interventions such as exercise and antioxidants supplementation when investigated independently have been beneficial counteracting oxidative stress and improving brain function in both human and animals. A large number of health conscious individuals often combine exercise with vitamin supplementation, anticipating a synergistic effect maximizing their performance. While some studies reported additive effects, others have also indicated a potential for an antagonistic action of the antioxidants on the beneficial effects of exercise. To date, it has not been well established what the nature of the interaction between antioxidant supplementation and exercise is in terms of functional outcomes and whether age will influence the outcomes. The purpose of this study was to determine if combination of antioxidant supplementation, and moderate exercise could ameliorate psychomotor and cognitive performance of young and old male mice Using vitamins C and E and a treadmill-based forced exercise in young and old C57BL/6J mice, we explored the nature of that interaction on functional and biochemical outcomes. We examined the mice for spatial learning and memory, working memory and executive function, coordinated running performance, muscular reflexes, spontaneous locomotor activity, anxiety and muscle strength. Our data suggested that the male mice exhibited age-associated declines in psychomotor and cognitive performance. Antioxidants supplementation worsened the cognitive flexibility of old mice but improved the depression-like symptoms in young mice. Overall, exercise training reversed the age-related declines in reflexes and balance of old mice, and improved strength and associative learning of young mice only. Furthermore, combination of exercise and antioxidant improved reflexes, motor and cognitive performance, but additive or antagonistic effects of antioxidants on the beneficial effects of exercise were not observed. Hence we can conclude that, combining antioxidants and exercise may not be provide any additional benefit in reversing age-related functional impairments.

Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.

Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.

Download or read book Antioxidants Exercise APOE Genotype and Brain Function written by Kiran Chaudhari and published by . This book was released on 2015 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apolipoprotein E4 (APOE4) is a well-established and extensively prevalent genetic risk factor for the development of Alzheimer’s disease (AD). The presence of APOE4 allele accelerates the pathophysiology and symptomology of AD. A large set (36%) of the population suffering from AD expresses APOE4. Being a chronic progressive disease with very few pharmaco-therapeutic agents approved by FDA, non-drug lifestyle modifications have been an important part of management of AD. People often eat healthy diet rich in antioxidants and focus on healthy living habits such as exercise. Health care providers frequently suggest combining antioxidants with physical activity for higher benefits. Antioxidants have been beneficial in counteracting oxidative stress and improving learning and memory. Similarly, different regimens of exercise also improved cognition and delayed development of AD. However, the nature of the interaction between antioxidants and exercise remain elusive and complicated. While some studies reported additive effects, others have also shown a concerning antagonistic action of the antioxidants on the beneficial effects of exercise. In the context of APOE genotype, we set our study to determine the nature of such interaction between antioxidants and exercise. Using vitamins C and E and a treadmill-based forced exercise in a genetically modified mouse model expressing human APOE3 and APOE4 (GFAP-APOE3, GFAP-APOE4), we explored the nature of that interaction on functional and biochemical outcomes. We examined the mice for spatial learning and memory, working memory and executive function, coordinated running performance, muscular reflexes, spontaneous locomotor activity, anxiety and muscle strength. Interestingly, we observed that the young adult mice expressing E4 allele performed better on higher brain functions including spatial learning and memory and short term memory in contrast to middle age mice, which developed a cognitive deficit as expected. Motor functions, reflexes and coordination were poor among all the mice carrying E4 allele irrespective of age. Antioxidants and exercise interventions led to outcomes that were dependent on genotype, age and the brain function under consideration. There was additive beneficial effect of combination of antioxidants and exercise on cognitive outcomes but not on motor outcomes in middle age groups. However, in young adults, an antagonistic interaction was observed on motor outcomes but no such interaction was observed on cognitive outcomes. Hence we can conclude that, combination of antioxidants and exercise is not a “fit for all” approach and needs to be tailored base on individual’s age and genotype.

Download or read book 365 Ways to Boost Your Brain Power written by Carolyn Dean and published by Simon and Schuster. This book was released on 2008-12-17 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: An apple a day doesn't just keep the doctor away, it can also improve memory. From eating the right foods to knowing the right exercises, becoming smarter isn't always about textbooks and tests. With this practical, interactive guide, you can amp up your IQ in no time! Filled with 365 tips and tricks to better the brain, you'll learn that: Gingko Biloba increases blood flow to the brain learning a new language improves brain function classical music will help your problem-solving abilities sitting up straight doesn't just elevate your body, it improves your thinking process taking a brisk walk builds a better connection between brain cells eating at least one cup of blueberries a day reduces the effects of Alzheimer's disease or dementia and other brain boosting facts! This book is all that's needed for smarter living—starting now.

Download or read book Handbook of Oxidants and Antioxidants in Exercise written by C. Sen and published by Elsevier. This book was released on 2000-02-16 with total page 1219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress. The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes. This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience.

Download or read book Antioxidants and Functional Foods for Neurodegenerative Disorders written by Abhai Kumar and published by CRC Press. This book was released on 2021-01-07 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection. Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.

Download or read book The Role of Natural Antioxidants in Brain Disorders written by Ali Imran and published by Springer Nature. This book was released on 2023-11-20 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and neuroinflammation are considered causative factors in various neurological disorders such as Parkinson’s and Alzheimer’s diseases. Antioxidants are chemicals that bind with oxidative species and nullify their effect from causing damage to biological molecules. Endogenous antioxidants are produced by our body, however most of them are obtained from external sources, primarily through diet, called dietary antioxidants. Major sources of antioxidants are brightly colored fruits, vegetables, cereals, legumes, and herbs. Other very effective sources are berries, green tea, and dark chocolate. These compounds have the potential to hinder neurodegeneration, reduce neuronal death and improve memory as well as cognitive functions. Based on the complex nature of antioxidants and oxidative stress, particular antioxidants such as vitamin E, vitamin C or β-carotene are beneficial in protecting cells, organs and tissues against oxidative damage. The Role of Natural Antioxidants in Brain Disorders describes various neuroprotective effects and their physiological phenomenon mediated by antioxidants to maintain and regulate the general health biomarkers against brain disorders. The important role of antioxidants, diet and lifestyle in managing brain disorders is covered, as is their use in conjunction with conventional therapies against oxidative stress. Both exogenous and endogenous antioxidants are explored in full. By focusing on the role of oxidative stress as a triggering mechanism for various brain disorders and the use of antioxidant foods in conjunction with traditional therapies in combating and preventing them, this is a valuable source for researchers in food science, nutrition, health science and physiology.

Download or read book Your Best Brain Ever written by Michael S. Sweeney and published by National Geographic Books. This book was released on 2013-12-31 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: National Geographic presents a comprehensive guide to fighting mental decline. With cutting-edge neuroscience, information about Alzheimer's, fascinating case studies, and tips to fight brain aging symptoms such as slower mental acuity and "senior moments," this smart, engaging guide will help keep your memory sharp and your mind active. Fun, age-defying exercises--from body stretches to word games to foods that help you think--help the brain perform at its best, just like exercising does for other parts of the body. Leading memory loss expert Cynthia R. Green, PhD, and eminent science writer Michael Sweeney have created a book both informational and practical that gives readers everything they need to know about the care and feeding of one of the body's most important organs: the brain.

Download or read book Oxidative Stress Exercise and Aging written by Helaine M. Alessio and published by Imperial College Press. This book was released on 2006 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together some of the leading researchers in the actively investigated field of oxidative stress, an area of study which is of importance to human health and disease. It examines oxidative stress in a variety of models, at rest and after exercise, in young and old. Key concepts of oxidative stress, exercise and aging are presented in clear and easy-to-understand terms. Oxidative stress in different types of exercises OCo isometric, isotonic and sports OCo is explained in detail, with several chapters focusing on acute and chronic adaptations of skeletal muscles following both aerobic and non-aerobic exercises. The book includes current knowledge of the underlying mechanisms influencing health and disease processes associated with oxidative stress. Contents: Chemistry of Reactive Oxygen Species and Antioxidants (D C Close & A E Hagerman); Oxidative Stress in Plants and Animals (D C Close & A E Hagerman); The Exercise Continuum (R L Wiley); Oxidative Stress and Muscle Size, Type, and Action (H M Alessio); Oxidative Stress Across the Exercise Continuum (H M Alessio); Oxidative Stress and Antioxidant Defense: Effects of Aging and Exercise (L L Ji); Muscle, Oxidative Stress and Aging (J S Moylan et al.); Aging, Exercise, Antioxidants, and Cardioprotection (J Quindry & S Powers); Genetic Expressions: Oxidative Stress, Exercise, and Aging (N B Schweitzer & H M Alessio). Readership: Academics, researchers, upper undergraduate and graduate students in biochemistry, biological chemistry, physiology, gerontology, and cell & molecular biology; companies that develop and market products for sports, health, antioxidants and anti-aging interventions."

Download or read book Diet and Exercise in Cognitive Function and Neurological Diseases written by Akhlaq A. Farooqui and published by John Wiley & Sons. This book was released on 2015-02-05 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and exercise have long been recognized as important components of a healthy lifestyle, as they have a great impact on improving cardiovascular and cerebrovascular functions, lowering the risk of metabolic disorders, and contributing to healthy aging. As a greater proportion of the world’s population is living longer, there has been increased interest in understanding the role of nutrition and exercise in long-term neurological health and cognitive function. Diet and Exercise in Cognitive Function and Neurological Diseases discusses the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into two sections. The first section focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean, ketogenic and vegan diets, as well as the role of specific nutrients, fats, fatty acids, and calorie restriction on neurological health and cognitive function. The second section of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters look at the impact of exercise in the management of specific neurological disorders such Multiple Sclerosis and Parkinson’s Disease. Diet and Exercise in Cognitive Function and Neurological Diseases is a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

Download or read book Association of Dietary Antioxidants and Physical Activity with Mental Health and Cognition in Older Adults written by Bharathi Ramesh and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress has been linked to the development of depression and anxiety as well as cognitive decline in older adults. Vitamins and minerals that have antioxidant properties or serve as cofactors, and physical activity, can improve the oxidant-antioxidant balance in the body and lead to a reduction in oxidative stress and inflammation. We aimed to study antioxidant and antioxidant cofactor intake from diet, and the effect of physical activity, in the older population in relation to mental and cognitive health. A cross-sectional study was conducted that included 128 men and women aged 65-80 years. Individuals diagnosed with dementia, Alzheimer's, or other neurological disorders were excluded. Dietary information was obtained using the Block Food Frequency Questionnaire. Mental and cognitive health were assessed using Geriatric Depression Scale, Geriatric Anxiety Inventory, Montreal Cognitive Assessment (MoCA), and Digit Span test. Pearson Correlation and hierarchical regression analyses were performed using SPSS software. Our findings indicate that dietary vitamin C [r = .22, n = 128, p .05] was positively correlated with Digit Span test score, although the relationship was weak. The results of hierarchical regression analysis showed that after controlling for antioxidant supplementation, age, education, BMI, and daily calorie intake, the final model containing the covariates and vitamin C did not account for a significant portion of the variance in the Digit Span test scores [R2 = .09, F (1, 121) = 4.88, beta = .25, p 0.05]. When the physical activity was added to the model, it did not significantly contribute to the variance in the Digit Span test scores. Our findings suggest that although vitamin C intake from food was positively associated with cognitive performance, the association did not remain significant when covariates such as age, education, BMI, antioxidant supplementation, and daily calorie intake were taken into account. Further studies, with larger sample sizes, are needed to better understand the role of vitamin C in the cognitive function of older adults.

Download or read book Physical Activity and the Aging Brain written by Ronald Ross Watson and published by Academic Press. This book was released on 2016-12-15 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer’s disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process. Presents research scientists with a complete understanding of the role of exercise in healthy brain aging Considers the roles of nutrition, the mind-body connection, and other lifestyle factors Presents a major resource for exercise and physical activity in the neurological health of older adults Provides a synopsis of key ideas associated with the many aspects of physical activity, along with lifestyle factors that can modify neurological diseases and age-related neurological decline

Download or read book Oxidative Stress and Free Radical Damage in Neurology written by Natan Gadoth and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinson’s are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.

Download or read book Superior Brain Health written by , empreender and published by Editora Bibliomundi. This book was released on 2021-12-15 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘Superior Brain Health’ is the ultimate guide for those who want to boost their brain power and protect their brain health so that they can be focused, alert, and solve problems creatively. You’ll discover how to maximize your cognitive abilities, increase your IQ, and avoid cognitive diseases like dementia.This research-backed guide will teach you everything you need to know about how to ensure that your brain is working at an optimum level.Follow the steps taught in this powerful guide and you’ll start noticing changes IMMEDIATELY.If you are sick and tired of feeling foggy and unfocused,If you want to have excellent memory and creativity,Then you owe it to yourself and everyone around you to learn the simple but powerful steps taught in ‘Superior Brain Health.’

Download or read book Micronutrients and Brain Health written by Lester Packer and published by CRC Press. This book was released on 2009-10-06 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micronutrients and Brain Health addresses cutting-edge research related to processes of oxidative stress that affect brain function, an area of increasing significance for those concerned and involved with public health and translational medicine. Edited by four leading micronutrient researchers, the book brings together the investigative work of m

Download or read book The Effect of Late life Antioxidant Supplementation on Brain Function written by Ritu A. Shetty and published by . This book was released on 2007 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: