Download or read book Antioxidants and Cardiovascular Disease written by R Nath and published by ALPHA SCIENCE INTERNATIONAL LIMITED. This book was released on 2004-01-01 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book authored by leading investigators in the field of Cardiovascular research and practicing clinicians across the globe details the scientific evidence for the heath effect of vitamins, antioxidants, trace elements and functional food, specifically their role in Cardiovascular system and provides up-to-date recommendations in the area of Cardiovascular nutrition including dietary micronutrients and supplements.Genetics of coronary disease as well as racial differences and risk factors, the role of Homocystine dietary fats, importance of antioxidant trace elements, genetic and racial differences especially in relation to cardiovascular effects, Clinical relevance of trace elements and minerals such as Chromium, Copper, Fluoride, Iron, Iodine, Molybdenum, Manganese, Selenium, Zinc, Calcium, Magnesium and Phosphorous have all been covered in relation to cardiovascular disease.
Download or read book Preventive Nutrition written by Adrianne Bendich and published by Springer Science & Business Media. This book was released on 2010-04-19 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this major revision and expansion of a highly respected reference work, the authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. This new edition combines fully updated versions of the best chapters of the first two editions with updated critical chapters from the much-praised Primary and Secondary Preventive Nutrition, and adds 16 new chapters. Here, practicing health professionals will find all new reviews of lycopene, tomatoes and prostate cancer, soy and cancer prevention; the effects of dietary supplement use on prescription drugs, osteoarthritis, osteoporosis, and cardiovascular disease; balanced, data-driven reviews of the effects of antioxidant supplements on health outcomes, and more. By synthesizing the latest data and integrating it into the broad body of existing information, this book provides in-depth guidance on nutrition and the prevention of cancer, cardiovascular disease, bone diseases, obesity, and diabetes, and on achieving optimal pregnancies and birth outcomes.
Download or read book Oxidative Stress and Vascular Disease written by John F. Keaney Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.
Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Download or read book Antioxidants and Stem Cells for Coronary Heart Disease written by Philip B Oliva and published by World Scientific. This book was released on 2014-01-22 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen. Contents:Part I:The French ParadoxLDL Oxidation — BrieflyAcetylation of LDLFree RadicalsThe Oxygen ParadoxRetrolental Fibroplasia from 1956 to 1972: The Quiet TimeThe Second Epidemic of Retrolental Fibroplasia: 1972–20??Cytokines and ChemokinesLDL Oxidation by Free Radicals — In DetailTwo Other Ways to Oxidize LDL: Lipoxygenase and Nitric OxideWhat is the Raison d'être for Oxidized LDL?Fatty Streaks and Foam CellsEmbryonic Stem CellsAdult Stem CellsTransgenic MicePart II:Treatment of Coronary Heart Disease with Antioxidants: An IntroductionThe Mediterranean DietAcute Myocardial Infarctions in Japan and Norway from 1910 to 1950Wine, Beer, and Spirits as AntioxidantsA Perspective on Antioxidant Vitamins for the Treatment of Coronary Heart DiseaseVitamin AThe Thalidomide SagaVitamin CVitamin EDo Combinations of Antioxidant Vitamins Work Better than Individual Vitamins in Patients with Coronary Heart Disease?A RequiemMolecular Markers, Reporter Genes and Suicide GenesStem Cells for the Heart: Hype or Hope?The PrizefightBrainbowCre/Lox: A Cut-and-Paste Method of Gene Swapping Without a Mac or PC and a New Scientific Term with Vast SignificanceBacteriophage, Transgenic Mice and Transgenic MarmosetsPhage Geometry and Soccer BallsEuler's FormulaE = mc2 and Einstein's BrainThe Manhattan Project and Its Connection with Albert EinsteinA Gadget, a Little Boy and a Fat ManCamillo Golgi and Santiago Ramón Y Cajal: Bitter Rivals to The End Readership: College-educated general public and non-scientists who are interested in the topic of antioxidants and stem cells. Key Features:The book is written in plain English and scientific jargons are explained in laymen terms“Hot topics” such as embryonic stem cells, adult stem cells and antioxidants are discussedA well-researched and colourfully illustrated book for readers of the general publicKeywords:Stem Cells;Antioxidants;Coronary Heart Disease
Download or read book Functional Foods written by I. Goldberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Accuse not Nature! She has done her part; Do Thou but Thine!" Milton, Paradise Lost 1667 The concept that nature imparted to foods a health-giving and curative function is not new. Herbal teas and remedies have been used for centuries and continue in use in many parts of the world today. In modern society, we have turned to drugs to treat, miti gate, or prevent diseases. However, since the discovery of nutrients and our increasing analytical capabilities at the molecular level, we are beginning to become more knowledgeable of the biochemical structure-function relationship of the myriad of chemicals that occur naturally in foods and their effect on the human body. The holistic approach to medicine and diet that began in the 1970s has now seen a renewal as we realize that certain foods, because of the presence of specific biochemicals, can have a positive impact on an individual's health, physical well-being, and mental state. In fact, because of the negative image of drugs, and the grey area of s- xi Foreword xii plements, the use of foods that are "functional" is becoming a growth area for the food industry. In Japan this concept has led to one of the largest growing markets, where they have defined "functional foods" as regular foods derived only from naturally occurring in gredients. The Japanese further require that the functional foods be consumed as part of the diet and not in supplement form (i. e.
Download or read book Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention written by J T Kumpulainen and published by Elsevier. This book was released on 1996-01-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural antioxidants and food quality in atherosclerosis and cancer prevention provides a comprehensive and up-to-date overview of the role of natural antioxidants and lipid peroxidation in atherosclerosis and cancer. The book presents important information on the presence of various flavonoids found in berries, vegetables and fruits and their antioxidative potencies, as well as the role of antioxidative vitamins and carotenoids in cardiovascular diseases and cancer. In addition, the measurement of oxidative stress in humans is surveyed.
Download or read book Modulation of Oxidative Stress in Heart Disease written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-10 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.
Download or read book Antioxidants in Health and Disease written by Antonis Zampelas and published by CRC Press. This book was released on 2015-06-09 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.
Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Download or read book Highway to Heart Health written by Ross Walker and published by . This book was released on 2000 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet therapy to combat heart disease.
Download or read book Fight Heart Disease with Vitamins and Antioxidants written by Kedar N. Prasad and published by Simon and Schuster. This book was released on 2014-11-20 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most complete and up-to-date resource on the powerful benefits of micronutrients for heart disease prevention and treatment • Provides an easy-to-follow program of nutritional supplements to halt the progression of heart disease and prevent its onset despite family history • Shows how merely changing your diet and activity level cannot fully counteract the chronic inflammation and free radical damage at the source of heart disease • Debunks flawed conclusions of the medical community that show vitamins and antioxidants to be ineffective for treatment of heart disease and high blood pressure In this practical scientific guide, leading researcher in cancer, heart disease, and diabetes prevention Kedar N. Prasad, Ph.D., reveals the latest revolutionary discoveries on the use of antioxidants and micronutrients to treat heart disease. He details how the proper combinations of vitamin and antioxidant supplements can greatly increase the effectiveness of standard medical treatments for heart disease as well as help balance cholesterol levels and blood pressure, minimize plaque and clot formation, reduce angina and atherosclerosis, and prevent onset of heart disease despite family history. Prasad shows how chronic inflammation, oxidative stress, homocysteine levels, and free radical damage are the chief culprits in the progression of heart disease and that merely changing your diet and activity level and regulating cholesterol and blood pressure cannot fully counteract an unhealthy internal state. He provides an easy-to-follow daily supplement regime for multiple age groups to target free radical damage and cell injury and stop the progression of heart disease and its related complications. Sharing the scientific data on familial heart disease and antioxidant use, he debunks the flawed conclusions of the medical community that vitamins and antioxidants are ineffective for heart disease, revealing how their studies focused on specific micronutrients rather than synergistic combinations. Offering the missing complement to the standard care of medications, diet, exercise, and lifestyle changes promoted by mainstream medicine, this guide provides a powerful approach to heart disease prevention, treatment, and care.
Download or read book Antioxidants and Cardiovascular Disease written by Jean-Claude Tardif and published by Springer Science & Business Media. This book was released on 2000 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work addresses a complex problem in cardiovascular medicine. It is written by experts in the fields of atherosclerosis, heart failure, and antioxidants. It should be of interest not only to academicians but also to practising physicians, including postdoctoral fellows, internists, cardiologists, and general practitioners. The first three chapters review the antioxidant hypothesis and its close relationship to lipid mechanisms of action and classify the different and heterogeneous pharmacological compounds with known antioxidant properties, and describe the role of dietary nutrients and supplements as well as the potential therapeutic benefit of antioxidants in coronary artery disease prevention and risk reduction, prevention of endothelial dysfunction, and prevention of chronic heart failure. Finally, current knowledge of the use of these compounds in cardiovascular medicine is summarized.
Download or read book Natural Antioxidants in Human Health and Disease written by Balz Frei and published by Academic Press. This book was released on 2012-12-02 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a comprehensive overview of the current scientific knowledge on the health effects of dietary and supplemental antioxidants (such as vitamins C and E). Chapters integrate information from basic research and animal studies, epidemiologic studies, and clinical intervention trials. The popular media has taken great interest in antioxidants, with numerous articles emphasizing their role in preventing disease and the possible slowing of the aging process. These antioxidant vitamins may be important in preventing not only acute deficiency symptoms, but also chronic disorders such as heart disease and certain types of cancer. This book, therefore, is not only for scientists and doctors, but also for health writers, journalists, and informed lay people. The text focuses on several human conditions for which there is now good scientific evidence that oxidation is an important etiological component. Specifically, antioxidants may prevent or slow down the progression of: Cancer, Cardiovascular disease, Immune system disorders, Cataracts, Neurological disorders, Degeneration due to the aging process.
Download or read book Reactive Oxygen Species and the Cardiovascular System written by Augusto C. Montezano and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) influence various physiological processes including host defense, hormone biosynthesis, and cellular signaling. Increased ROS production (oxidative stress) is implicated in many diseases of the cardiovascular system, including hypertension, atherosclerosis, cardiac failure, stroke, diabetes, and kidney disease. ROS are produced throughout the cardiovascular system, in the kidney and central and peripheral nervous system. A major source for cardiovascular, renal, and neural ROS is a family of non-phagocytic NAD(P)H oxidases, including the prototypic Nox2 homologue-based NAD(P)H oxidase, as well as other NAD(P)H oxidases, such as Nox1 and Nox4. Other possible sources include mitochondrial electron transport enzymes, xanthine oxidase, cyclooxygenase, lipoxygenase, and uncoupled nitric oxide synthase (NOS). NAD(P)H oxidase-derived ROS is important in regulating endothelial function and vascular tone and oxidative stress is implicated in endothelial dysfunction, inflammation, hypertrophy, apoptosis, migration, fibrosis, angiogenesis and rarefaction, important processes involved in vascular remodeling in cardiovascular disease. These findings have evoked considerable interest because of the possibilities that therapies targeted against non-phagocytic NAD(P)H oxidase to decrease ROS generation and/or strategies to increase nitric oxide (NO) availability and antioxidants may be useful in minimizing vascular injury and thereby prevent or regress target organ damage associated with hypertension and other cardiovascular diseases.
Download or read book Oxidative Stress in Microbial Diseases written by Sajal Chakraborti and published by Springer. This book was released on 2019-11-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances in our understanding of the role of oxidants in microbial pathophysiology, providing valuable insights into the complex role of reactive oxygen species (ROS) in host-microbial interactions. The various chapters take readers through the function of ROS in infections ranging from viral to bacterial, and describe how microorganisms have developed complex strategies to not only avoid contact with phagocyte-derived oxidants, but also protect themselves from injury when oxidants are encountered. Featuring the latest research in the field of microbial diseases, this timely book is a ready reference for scientists looking to develop new anti-microbial drugs.
