Download or read book ANTIMICROBIAL EFFECTS IN VITRO OF SILVER DIAMINE FLUORIDE AGAINST SELECTED HUMAN RED AND ORANGE COMPLEX PERIODONTAL PATHOGENS written by Guillermo Jose Ramirez-Martinez and published by . This book was released on 2019 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objectives: Silver diamine fluoride is approved by the United States Food and Drug Administration for intraoral human treatment of tooth hypersensitivity, and it has also been employed world-wide as an emerging method to arrest tooth decay. A 38% silver diamine fluoride formulation, comprised of 25% silver, 5% fluoride, and 8% ammonia as a solvent, is commercially available in the United States. One of the main mechanisms underlying the dental caries arrest potential of silver diamine fluoride is the silver component, which exerts pronounced antimicrobial activity against cariogenic bacteria. Interestingly, studies initiated in the late 1990s demonstrated marked susceptibility of periodontal bacterial pathogens to silver nitrate. However, efforts to develop silver-based, slow-release biodegradable wafers for subgingival placement into periodontal pockets were not commercially successful. At present, no commercial products are available which employ silver ions to combat periodontal bacterial pathogens in periodontal disease treatment. It is not known whether the 38% silver diamine fluoride product commercially available in the United States possesses antimicrobial activity against periodontal bacterial pathogens, and potentially, have application in periodontal therapeutic regimens. As a result, the objective of this study was to test the in vitro antimicrobial effects of silver diamine fluoride on freshly-isolated red and orange complex periodontal pathogens from severe human periodontitis lesions. Methods: Paper point subgingival biofilm samples from 24 adults with severe periodontitis that were to be discarded after microbiological analysis at the Temple University School of Dentistry Oral Microbiology Testing Service Laboratory were secondarily employed in this study. Dilution aliquots from each subgingival specimen were mixed with either 38% or 19% silver diamine fluoride, inoculated onto enriched Brucella blood agar plates, and incubated anaerobically for 7 days at 37°C. Bacterial species growing subsequent to the silver diamine fluoride exposure were considered to be resistant to that concentration of silver diamine fluoride. Total viable counts in silver diamine fluoride-exposed subgingival specimens were quantitated, and established phenotypic criteria employed to identify the following red and orange complex periodontal pathogens: Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia/nigrescens, Parvimonas micra, Campylobacter rectus, Fusobacterium nucleatum group species, and Streptococcus constellatus. Other cultivable isolates recovered from silver diamine fluoride-exposed subgingival specimens were identified using matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry and Bruker MALDI Biotyper analytic software. Subgingival sample dilution aliquots not exposed to silver diamine fluoride were similarly processed as controls for comparison with silver diamine fluoride-exposed specimens Paired t-tests compared mean total subgingival viable counts, and mean total subgingival proportions of the evaluated anaerobic red and orange complex periodontal pathogens per patient, between subgingival biofilm samples exposed and not exposed in vitro to 38% or 19% silver diamine fluoride, with a P-value of
Download or read book In vitro investigations into the antimicrobial and microecological effects of selected anti plaque agents written by Mohamad Mohamad and published by . This book was released on 2011 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate on Various Cariogenic Bacteria written by Reham AlNajjar and published by . This book was released on 2019 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purpose: The use of silver-based antimicrobials is an emerging method for the treatment of dental caries. In this study, the authors compare the efficacy of the two most prominent silver- based therapeutics, silver diamine fluoride (SDF) and silver nitrate (AgNO3), on cariogenic and non-cariogenic multispecies biofilms. Currently there is a lack of studies comparing the efficacy of SDF to AgNO3. Methods: Plaque samples from anterior and posterior tooth sites from children presenting both with early childhood caries and caries-free children were collected, pooled, and utilized to create four ex vivo biofilm systems in artificial saliva. SDF and AgNO3 were administered to these biofilms and bacterial survival was quantified and compared to untreated controls. Results: Each of the four pooled sample types was applied to plates coated in artificial saliva + 1% sucrose. Both SDF and AgNO3 were very effective against plaque derived biofilms when compared to untreated biofilms (P0.05) in the potency of each compound. Conclusions: SDF and AgNO3 significantly inhibit ex vivo cariogenic and non-cariogenic biofilms at similar levels.
Download or read book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate written by Nicholas L. Luke and published by . This book was released on 2018 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purpose: To determine the antimicrobial efficacy of SDF and SN/NaF. Methods: Three bacterial species were combined to create an in vitro biofilm. Treatment was completed with SN, SN/NaF, SDF, SDF1⁄2 or untreated (control). Results: The untreated group demonstrated significantly higher growth than all other treatment groups across the study. On the BHI-plates (1-day), there were significant differences between all treatments except SDF and SDF1⁄2. On the BHI-plates (3-days), SN/NaF was not significantly different from SDF or SDF1⁄2. On the L-MRS-plates (1-day), both SN treatment groups yielded significantly higher growth than the SDF groups. On the L-MRS-plates (3-days), SN yielded significantly higher growth than SN/NaF, SDF, and SDF1⁄2. Conclusion: SDF is more effective than SN/NaF, with the exception of BHI-plates (3-days) only and SN/NaF is more effective than SN on primarily S. mutans and L. acidophilus. There is evidence of a possible antimicrobial tolerance of oral bacteria to silver.
Download or read book Longitudinal in Vitro Effects of Silver Diamine Fluoride on Early Enamel Caries Lesions written by Alice-Anne Thompson Alcorn and published by . This book was released on 2020 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of Silver Diamine Fluoride on Oral Bacteriome and Mycobiome written by Mayura Manerkar and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction: Silver diamine fluoride (SDF) is a simple and non-invasive agent to arrest caries in children. The purpose of this study is to investigate changes to the oral bacteriome and mycobiome in young children treated with SDF Methods: Plaque samples were collected from 45 children with early childhood caries (ECC). Frequency regimens of SDF were two applications 4 months apart (4M), two applications 6 months apart (6M), and two applications 1 month apart (1M). DNA was extracted and sent to Genome Quebec Innovation Center for library preparation and paired-end Illumina MiSeq PE300 sequencing of the V4 region of bacterial 16S rRNA and fungal ITS1 rRNA genes. Sequencing data was analyzed using QIIME2 2018.11. Results: A total of 195 carious lesions in 44 children were treated at baseline and followed over two subsequent study visits. The overall arrest rates were 77.69% at Visit 2 and 93.61% at Visit 3 respectively. Arrest rates were higher for all lesions after two applications of SDF. The alpha diversity and beta diversity analysis showed no significant differences in the supragingival bacteriome and mycobiome for all three regimens. Taxonomic assignment showed that Streptococcus, Corynebacterium and Actinomyces were the most abundant genera for Bacteria and Candida, Blumeria, and Malassezia were the most abundant genera for Fungi. Streptococcus mutans and Veillonella dispar both showed a decrease in relative abundance, but these changes were a trend and not found to be statistically significant. Candida albicans was highly abundant in all groups regardless of number of visits or regimens. The differential abundance analysis showed significant changes in both bacterial and fungal species, particularly Lactobacillus spp., Bifidobacterium spp. and Candida spp. Our study found a vast diversity of fungal species and differential abundance analysis suggested that SDF treatment may have an effect on the abundance of specific fungi. Conclusion: SDF was an effective modality for arresting dental caries with higher arrest rates for all lesions after two applications of SDF. Further studies with a larger sample size are needed to confirm whether the presence or absence of various bacterial and fungal species are the result of SDF application at various frequencies.
Download or read book Biocompatibility of Dental Materials written by Gottfried Schmalz and published by Springer Science & Business Media. This book was released on 2008-10-10 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and scientifically based overview of the biocompatibility of dental materials. Up-to-date concepts of biocompatibility assessment are presented, as well as information on almost all material groups used in daily dentistry practice. Furthermore, special topics of clinical relevance (e.g,, environmental and occupational hazards and the diagnosis of adverse effects) are covered. The book will: improve the reader’s ability to critically analyze information provided by manufacturers supply a better understanding of the biocompatibility of single material groups, which will help the reader choose the most appropriate materials for any given patient and thus prevent adverse effects from developing provide insights on how to conduct objective, matter-of-fact discussions with patients about the materials to be used in dental procedures advise readers, through the use of well-documented concepts, on how to treat patients who claim adverse effects from dental materials feature clinical photographs that will serve as a reference when analyzing clinical symptoms, such as oral mucosa reactions.
Download or read book Pediatric Restorative Dentistry written by Soraya Coelho Leal and published by Springer. This book was released on 2018-09-11 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes and discusses the different restorative options for managing carious lesions in children with primary and mixed dentition. The aim is to provide practitioners with thorough, up-to-date information that will improve their clinical practice. The opening chapters present a comprehensive overview regarding diagnosis of carious lesions, risk assessment, child behavior and development, and behavioral management. The importance of oral health promotion and prevention in controlling lesion progression and maintaining oral health is reviewed. The impact of various factors on clinician decision making is then explained in detail, examples including the type of dentition (primary versus permanent), the clinical and radiographic aspect of the dentine carious lesion (noncavitated or cavitated), and whether the lesion is associated with a developmental defect. Guidance is provided on selection of nonoperative versus operative interventions, and the restorative materials most frequently used in pediatric dentistry are fully described, highlighting their advantages and disadvantages. Readers will also find an informative series of cases, with explanation of the choices in terms of materials and approach.
Download or read book Evidence Based Caries Prevention written by Ece Eden and published by Springer. This book was released on 2016-09-29 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to define the etiological factors in dental caries and to guide the clinician towards methods of caries prevention that are evidence based. The coverage includes discussion of the active role of the biofilm and the oral environment and emphasizes the multifactorial etiology of dental caries. The opening chapters describe the early detection and diagnosis of dental caries, highlight the value of caries risk assessment to the patient, and explain the dynamic process of the demineralization–remineralization cycle. Information is presented on the action of fluoride, and the evidence relating to the use and effectiveness of remineralization agents and biomimetic materials is reviewed. Additionally, the effects of antimicrobials such as chlorhexidine and ozone are summarized. Further chapters focus on dietary counseling (with information on sweeteners and probiotics), the effectiveness of sealants in caries prevention, and resin infiltration. The philosophy of prophylaxis and ways to improve patient compliance and achieve proper mechanical plaque removal are discussed. The book is concluded with a chapter discussing preventive actions in representative cases.
Download or read book Nanotechnology in Endodontics written by Anil Kishen and published by Springer. This book was released on 2015-03-18 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on the emerging applications of nanomaterials and nanoparticles within endodontics, highlighting the exciting potential clinical impact of nanotechnology in the field. The range of applications covered is diverse, encompassing drug and gene delivery, tissue engineering, antibacterial strategies, dentin tissue stabilization, dentin pulp regeneration and use in restorative and endodontic materials. Important scientific background information relating to each application is provided, with clear coverage of basic principles. In addition, potential pitfalls are identified and explained. The cytotoxicity of nanomaterials and nanoparticles is also addressed in a separate chapter. The book will be of value both for endodontic practitioners and for all scientists and graduate students who are interested in the application of nanotechnology in endodontics.
Download or read book Dental Composite Materials for Direct Restorations written by Vesna Miletic and published by Springer. This book was released on 2017-11-25 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers both basic scientific and clinically relevant aspects of dental composite materials with a view to meeting the needs of researchers and practitioners. Following an introduction on their development, the composition of contemporary composites is analyzed. A chapter on polymerization explains the setting reactions and light sources available for light-cured composites. The quality of monomer-to-polymer conversion is a key factor for material properties. Polymerization shrinkage along with the associated stress remains among the most challenging issues regarding composite restorations. A new classification of dental composites is proposed to offer more clinically relevant ways of differentiating between commercially available materials. A review of specific types of composites provides an insight into their key issues. The potential biological issues of dental composites are reviewed in chapters on elution of leachable substances and cariogenicity of resin monomers. Clinical sections focus on material placement, finishing procedures, and the esthetics and clinical longevity of composite restorations. Bonding to tooth tissues is addressed in a separate chapter, as is the efficiency of various composite repair methods. The final chapter discusses future perspectives on dental composite materials.
Download or read book Clinical Cases in Dental Hygiene written by Cheryl M. Westphal Theile and published by John Wiley & Sons. This book was released on 2019-01-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Cases in Dental Hygiene is an indispensable resource to understanding both the theory and practice of dental hygiene, illustrated by real-life cases in a clinically relevant format. Offers a unique case-based format that supports problem-based learning Promotes independent learning through self-assessment and critical thinking Includes a wealth of relevant cases for understanding dental procedures and management of patients Covers all essential topics within the scope of dental hygiene
Download or read book Modern Operative Dentistry written by Carlos Rocha Gomes Torres and published by Springer Nature. This book was released on 2019-12-14 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the theoretical knowledge required by students when learning how to diagnose oral diseases, plan treatment, and perform various types of dental restoration. It is also useful for clinicians wishing to update their treatment skills and broaden their understanding operative dentistry.Adopting an evidence-based approach, and in accordance with the philosophy of minimally invasive dentistry, it explains in detail the use of both classic and new restorative materials in various clinical situations. It also discusses the principles of smile analysis, as well the technique for esthetic composite restorations on posterior and anterior teeth, including direct and indirect veneers. In addition to richly illustrated, step-by-step descriptions of procedures, it offers essential information on basic topics, such as dental instruments and equipment, nomenclature and general principles of tooth preparation, isolation of the operating field, matrix and wedge systems, light curing, and pulpal protection. Furthermore it addresses the diagnosis of dental caries and tooth sensitivity of non-carious origin, like dentin hypersensitivity, dental erosion and cracked tooth syndrome, together with their treatment options. Also explaining the fundamental ergonomic principles of clinical practice, the book enables undergraduate students to embark on a successful professional career.
Download or read book SMART Oral Health written by Steven R Duffin and published by Independently Published. This book was released on 2019-11-21 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively evaluates the Medical Management of Caries using silver, fluoride, and glass ionomer compounds. The topics discussed involve history, scientific research, case reports, large scale clinical trials and community health programs throughout the world. Additional topics include economics of healthcare delivery, social determinants of disease, policy recommendations and future implications for the implementation of the Medical Management of Caries. Contributing to this book are 32 authors who comprise some of the most well known researchers and clinicians around the world.This material will be useful for school curriculum's, clinicians looking to learn new methodologies and public health professionals developing community health programs domestically and internationally. Implications to public health policy include reduced cost, increased access and improved quality of care.
Download or read book Eco Friendly Adhesives for Wood and Natural Fiber Composites written by Mohammad Jawaid and published by Springer Nature. This book was released on 2021-01-21 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of eco-friendly resins and their composite materials covering their synthesis, sources, structures and properties for different industrial applications to support the ongoing research and development in eco-friendly and renewable commercial products. It provides comparative discussions on the properties of eco-friendly resins with other polymer composites. It is a useful reference on bio-based eco-friendly polymer resins, wood-based composites, natural fibers and biomass materials for the polymer scientists, engineers and material scientists.
Download or read book Oral Rehabilitation for Compromised and Elderly Patients written by Alexandre Mersel and published by Springer. This book was released on 2018-11-29 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to help dentists in general practice to improve the results of prosthetic procedures in medically compromised and elderly patients. In particular, it critically scrutinizes various dogmas that govern practitioners’ approaches yet lack sound scientific support and often have an adverse effect on outcomes. Attention is drawn to straightforward procedures that offer significant clinical benefits and to aspects that are too often neglected, such as the impact of systemic diseases. New light is cast, for example, on the taking of dental impressions, the treatment of malocclusions, the making of jaw relation records, the relationship between denture quality and patient satisfaction, and the use of implant-supported overdentures versus traditional complete prostheses (dentures). As Albert Einstein once said, "It is what we think we know that prevents us from learning more." Readers will find that this book helps them to re-examine taken-for-granted elements of their practice, leading to improved care and patient satisfaction.
Download or read book Advanced Functional Materials from Nanopolysaccharides written by Ning Lin and published by Springer Nature. This book was released on 2019-11-15 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the latest research on nanopolysaccharides in the development of functional materials, from their preparation, properties and functional modifications to the architecture of diverse functional materials. Polysaccharide-based nanoparticles, including nanocellulose, nanochitin, and nanostarch have attracted interest in the field of nanoscience, nanotechnology, and materials science that encompasses various industrial sectors, such as biomedicine, catalyst, coating, energy, optical materials, environmental materials, construction materials, and antibacterial materials. This book establishes a fundamental framework, highlighting the architecture strategies of typical functional systems based on nanopolysaccharides and integrated analysis of their significant influence and properties to various functional behaviors of materials, to help readers to fully understand the fundamental features of nanopolysaccharides and functional materials. Addressing the potential for practical applications, the book also covers the related industrial interests and reports on highly valued products from nanopolysaccharides, providing ideas for future studies in the area. Intended both for academics and professionals who are interested in nanopolysaccharides, it is also a valuable resource for postgraduate students, researchers, and engineers involved in R&D of natural polymers, nanotechnology, and functional materials.
