Download or read book Anti inflammatory Effects of Cardiovascular Exercise written by Victoria Jeanne Vieira and published by ProQuest. This book was released on 2009 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic consumption of a diet high in saturated fat (HFD) combined with a sedentary lifestyle has led to the obesity epidemic and its associated metabolic complications. At the heart of the metabolic aberrations that lead to obesity-associated diseases is inflammation that occurs in the visceral white adipose tissue (WAT). Reducing WAT inflammation, even in the absence of body weight changes, improves the metabolic consequences of obesity, highlighting the importance of the physiology of the WAT in the treatment of metabolic diseases. Exercise (EX) has been shown to reduce systemic inflammation, and this effect may be mediated by an EX-associated reduction in WAT inflammation. The overarching hypothesis of this work was that EX lowers inflammation in the visceral WAT as well as in the periphery, and that the mechanism involves, but is not fully explained by, a reduction in visceral WAT. This hypothesis was tested using one human intervention trial and two animal studies. In the first study, previously sedentary older adults participated in 10 months of cardiovascular (Cardio) or non-cardiovascular (Flex) EX. Cardio experienced significant improvements in fitness, systemic inflammation (as measured by serum C-reactive protein, CRP), as well as total and central (i.e., trunk) fat. Only the decrease in trunk fat was significantly related to the reduction in CRP, suggesting that the mechanism behind the anti-inflammatory effect of EX may involve a reduction in visceral WAT. In the second study, Balb/c mice were fed an HFD for 12 wks and then were randomized to 1 of 4 groups where they either remained on HFD and sedentary (HFSED), were exercise trained (HFEX), switched to an LFD (LFSED), or switched to an LFD and exercise trained (HFEX) for 12 wks. LFD and EX had differential effects on WAT gene transcription (MCP-1, F4/80, IL1ra), IR, and HS. In the final animal study, C57BL/6 mice were fed an HFD for 6 wks and then were randomized to HFSED, HFEX, LFSED, or LFEX for a 6 or a 12-wk intervention. EX and LFD both decreased weight gain and relative body fat, although LFD had a more robust effect than EX. Reductions in visceral WAT explained the decreases in WAT inflammation, IR, and HS seen at 6 wks. However, by 12 wks, unique independent effects of EX and LFD emerged such that both treatments reduced WAT inflammation and metabolic complications. WAT macrophage infiltration was the most important independent predictor of IR whereas visceral fat mass most strongly predicted HS. In summary, there are unique metabolic consequences of a sedentary lifestyle and chronic consumption of an HFD. Both LFD and EX are critically important behavioral strategies to improve WAT health and whole body metabolic function.
Download or read book Antioxidants in Sport Nutrition written by Manfred Lamprecht and published by CRC Press. This book was released on 2014-09-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Download or read book The Anti inflammatory Effects of Exercise written by Pedro Tauler and published by Nova Science Publishers. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews and examines the novel findings regarding anti-inflammatory effects of aerobic exercise. Furthermore, the authors discuss to what extend the exercise induced anti-inflammatory response may play a therapeutic role in chronic diseases associated with low-grade inflammation. Evidences for the anti-inflammatory healthy effects of regular continuous exercise are presented in this book.
Download or read book Are the Anti inflammatory Effects of Aerobic Exercise Training Adequate to Offset the Pro inflammatory Effects of a High fat Feeding in a Murine Model written by Lisa M. Esposito and published by . This book was released on 2008 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chronic Exercise Leads to Antiaggregant Antioxidant and Anti inflammatory Effects in Heart Failure Patients written by and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inflammation in Heart Failure written by Matthijs Blankesteijn and published by Academic Press. This book was released on 2014-12-05 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases
Download or read book The Benefits Of Performing Cardio Exercises The Best Cardio Exercises For Optimizing Your Health How To Perform The Best Cardio Exercises Deadly Disease Causing Foods That You Should Never Consume And How To Mitigate Risks For Diseases written by Dr Harrison Sachs and published by . This book was released on 2020-02-17 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds light on the benefits of performing cardio exercises and identifies the utmost best cardio exercises for optimizing your health. Moreover, how to perform the best cardio exercises and deadly disease causing foods that you should never consume are delineated in this essay. How to substantially mitigate risks for life threatening chronic diseases by embracing a heart healthy, anticancer, nutrient dense, alkaline, antioxidant rich, anti-inflammatory, raw fruitarian diet is expounded upon in this essay. While typically neglectfully overlooked, the importance of performing cardio exercise should not be deprioritized nor relegated to the back burner. Cardio exercises, also known as aerobic exercises, offer a myriad of salubrious health benefits to workout enthusiasts. Cardio exercises are easy to undergo and can be performed virtually anywhere. The benefits of consistently performing cardio exercises are eminently profound and can play a salient role in allowing you to optimize your overall health. Performing cardio exercises confers a myriad of health benefits to the individual that encompass bolstering your heart health, increasing your metabolism, optimizing your blood sugar health, eliciting weight loss, and improving your body's hormonal profile. Undergoing cardio exercises regularly will also help you release endorphins, detoxify the body, improve your stamina, and become less apt to succumb to depression and chronic stress. Additionally, partaking in cardio exercises will reduce your blood pressure, decrease your LDL cholesterol levels, boost your mood, provide you with stress reduction, and improve your sleep quality. Undergoing cardio exercises also offer the individual the salutary benefits of being able to attenuate inflammation, eliminate body fat, and reduce their risk of contracting a life threatening chronic disease, such as cardiovascular disease, type 2 diabetes, and cancer. Cardio exercises are also able to relax the walls of blood vessels and optimize your blood flow. The benefits cardio exercises provide fitness enthusiasts are ultimately ineffably profound and life changing, especially if they can attribute to increasing your longevity, bolstering your cardiovascular health, preempting acute inflammation, staving off chronic diseases, optimizing your hormonal balance, and allowing you to alleviate chronic stress. Performing cardio exercises daily will culminate in you being more apt to manifest a positive outlook on life and an abundance mindset as you continually push yourself to improve your endurance and surpass your past limits. Moreover, performing cardio exercises can increase your lung capacity, alleviate anxieties, enhance blood circulation, boost your confidence, and can even amplify your bone density if you opt to undergo weight bearing cardio exercises. There are ample cardio exercises that you should undergo if you are keen on taking the necessary measures toward optimizing your overall health. First and foremost, one of the utmost best cardio exercise for increasing foot speed, burning calories, and strengthen cardiovascular health entails jumping rope. Jumping rope is a simple cardio workout and is able to increase your should strength, improve your coordination, and also stimulate sprinting. The utmost potent way to eliminate fat by jumping rope involves jumping rope in intervals of fast jumps followed by slows jumps. You should aim to jump as fast as viably possible for a one minute duration and then subsequently perform slow jumps for 20-30 seconds before recommencing the fast jumps. You can repeat this regimented jumping rope cardio exercise routine for at least 30 minutes in order to expend 500 calories from the jumping rope cardio workout. Jumping rope is a staple cardio exercise in a competitive boxer's training regimen and is easy to undergo even as a frequent traveler, All you need to perform this salubrious cardio workout is a jump rope which can fit into backpacks.
Download or read book Immune Function in Sport and Exercise written by Michael Gleeson and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. Designed to help readers understand and evaluate the relationship between exercise, immune function and infection risk, this book presents evidence for the "J-shaped" relationship between exercise load and infection risk. It also describes the components of the human immune system and key functions that protect the body from disease, the impact of acute and chronic psychological stress on immune function, and practical guidelines for minimizing the risk of immunodepression and infection in athletes. Further chapters explore different ways of measuring immune function, as well as the effects of heavy training on innate and specific (acquired) immunity, exercise in environmental extremes, and nutrition. Connections between exercise, infection risk, and immune function in special populations (elderly, obese, diabetic and HIV patients) are also addressed. Authored by a team of highly experienced experts. The "J-shaped" relationship between exercise load and infection risk is described, backed by current research and evidence. Components of the immune system and normal immune function are explained in detail, as well as methods for measuring immune function. The impact of acute and chronic psychological stress on immune function is presented, along with suggestions for minimizing the risk of immunodepression and infection in athletes. The effects of heavy training, exercise in environmental extremes, and nutrition are discussed with regard to their impact on innate and specific (acquired) immunity. Immune function in special populations (elderly, obese, diabetic and HIV patients) is also addressed, exploring links between exercise and infection risk in these groups. Evidence-based coverage includes a list of references in each chapter, as well as suggestions for further reading that direct readers to important texts and review articles. Information is presented in an easily accessible format, following a logical progression of material. LEach chapter begins with a list of learning objectives and ends with a list of key points to reinforce learning. A glossary at the end of the book defines all key terms and abbreviations.
Download or read book Physical Activity Health written by Jerome E. Kotecki and published by Jones & Bartlett Learning. This book was released on 2016-12-15 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Activity and Health, Fifth Edition offers expert knowledge based on the latest scientific evidence from physical activity and health research along with a variety of instructive elements that assist and encourage students in developing a personalized physical activity and health plan. The goal of the book is to introduce concepts and to develop the skills and interest to make physical activity a life-long habit. This text equips students with the information, skills, and practical know-how to gain control of their health and decide what to do and how and when to do it.
Download or read book Aerobic Exercise Training Effect on In Vivo and In Vitro Vascular Endothelial Inflammatory Indices in African Americans written by Dianne Babbitt and published by . This book was released on 2014 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to evaluate the in vivo influence of aerobic exercise training (AEXT) on the anti-inflammatory biomarker interleukin-10 (IL-10), the inflammatory biomarkers interleukin-6 (IL-6) and C-reactive protein (CRP), the endothelial activation marker CD62E+ endothelial microparticle (EMP), and the vasodilatory biomarker nitric oxide (NO) in an African American cohort. A secondary purpose was to conduct a complementary in vitro study on the influence of IL-10 and laminar shear stress (LSS) on African American endothelial cells. In Vivo Methods: The subjects were sedentary, putatively healthy, 45-71 y/o African American men and women. A pre-post study design was employed with baseline and post-intervention evaluations of office blood pressure, fasting blood sampling, and graded exercise testing. Subjects engaged in AEXT three times per week for six months at an intensity equivalent to 65% of their VO2max. Plasma concentrations of IL-10 and IL-6 were determined using an enzyme-linked immunosorbent assay. Levels of nitric oxide metabolites (NOx) were determined using a modified Griess assay. Plasma samples for CRP were sent to Quest Diagnostics Inc. for analysis. Circulating CD62E+ EMPs were quantified using a flow cytometer. In Vitro Methods: Human umbilical vein endothelial cells (HUVEC) from an African American donor were cultured and exposed to four experimental conditions: Static, Static with IL-10 Incubation, LSS at 20 dynes/cm2, and LSS at 20 dynes/cm2 with IL-10 Incubation. Western blotting experiments were conducted to measure endothelial nitric oxide synthase (eNOS) protein expression and its phosphorylated form (p-eNOS) at Serine 1177 in the cells in all four conditions. A modified Griess assay was used to measure NOx in the cell culture supernatant. In Vivo Results: There was a significant increase in NO (n=24; p=0.002), a significant decrease in IL-6 (n=32; p=0.04), a significant decrease in CRP (n=37; p=0.01), and a significant decrease in CD62E+ EMPs (n=28; pIn Vitro Results: Protein expression levels of both eNOS and p-eNOS were significantly increased in the LSS at 20 dynes/cm2 and LSS at 20 dynes/cm2 with IL-10 Incubation experimental conditions when compared to the Static experimental condition. NO concentration levels were significantly increased in the LSS at 20 dynes/cm2 and LSS at 20 dynes/cm2 with IL-10 Incubation experimental conditions when compared to the Static experimental condition. Conclusion: Based on these results, AEXT may be a viable, non-pharmacologic method to improve vascular inflammation status and vasodilation, and thereby contribute to reduced hypertension and cardiovascular disease risk in African Americans.
Download or read book Cardiovascular Response to Exercise written by Gerald F. Fletcher and published by Wiley-Blackwell. This book was released on 1994 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this popular and successful text has been fully revised and updated to take account of recent advances in the field, particularly in the physiology and pathophysiology of many disease processes. The text retains the original format of relevant physiology, test selection and test interpretation by case example. Essential aspects of paediatric chemical pathology, inborn errors of metabolism, reproductive endocrinology, tumours and toxicology are now included. As chemical pathology is receiving specific attention in medical courses, this text has been adapted to present this information in an understandable form, making it suitable for medical undergraduates and for medical and science postgraduates studying for exams of Colleges of Pathology and professional associations."
Download or read book The ESC Handbook on Cardiovascular Pharmacotherapy written by Juan Carlos Kaski and published by European Society of Cardiology. This book was released on 2019-05-23 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drugprescribing.Previously published as Drugs in Cardiology, this new edition has been developed by the ESC Working Group on Cardiovascular Pharmacology. Pharmacology is an integral aspect in almost all disciplines within cardiology and all cardiologists use cardiovascular drugs.Completely updated and aligned with the ESC Clinical Practice Guidelines for prescribing, this handbook is essential reading for consultants, registrars in training, general practitioners, specialist cardiac nurses and cardiovascular pharmacologists.
Download or read book Global Action Plan on Physical Activity 2018 2030 written by World Health Organization and published by World Health Organization. This book was released on 2019-01-21 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regular physical activity is proven to help prevent and treat noncommunicable diseases (NCDs) such as heart disease stroke diabetes and breast and colon cancer. It also helps to prevent hypertension overweight and obesity and can improve mental health quality of life and well-being. In addition to the multiple health benefits of physical activity societies that are more active can generate additional returns on investment including a reduced use of fossil fuels cleaner air and less congested safer roads. These outcomes are interconnected with achieving the shared goals political priorities and ambition of the Sustainable Development Agenda 2030. The new WHO global action plan to promote physical activity responds to the requests by countries for updated guidance and a framework of effective and feasible policy actions to increase physical activity at all levels. It also responds to requests for global leadership and stronger regional and national coordination and the need for a whole-of-society response to achieve a paradigm shift in both supporting and valuing all people being regularly active according to ability and across the life course. The action plan was developed through a worldwide consultation process involving governments and key stakeholders across multiple sectors including health sports transport urban design civil society academia and the private sector.
Download or read book Exercise Immunology written by Michael Gleeson and published by Routledge. This book was released on 2013-06-26 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercise immunology is an important, emerging sub-discipline within exercise physiology, concerned with the relationship between exercise, immune function and infection risk. This book offers a comprehensive, up-to-date and evidence-based introduction to exercise immunology, including the physiological and molecular mechanisms that determine immune function and the implications for health and performance in sport and everyday life. Written by a team of leading exercise physiologists, the book describes the characteristics of the immune system and how its components are organised to form an immune response. It explains the physiological basis of the relationship between stress, physical activity, immune function and infection risk, and identifies the ways in which exercise and nutrition interact with immune function in athletes and non-athletes. The book shows students how to evaluate the strengths and limitations of the evidence linking physical activity, immune system integrity and health, and explains why exercise is associated with anti-inflammatory effects that are potentially beneficial to long-term health. Every chapter includes useful features, such as clear summaries, definitions of key terms, discussions of seminal research studies and practical guidelines for athletes on ways to minimise infection risk, with additional learning resources available on a companion website. This is an essential textbook for any course on exercise immunology or advanced exercise physiology.
Download or read book Exercised written by Daniel Lieberman and published by Pantheon. This book was released on 2021-01-05 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book tells the story of how we never evolved to exercise - to do voluntary physical activity for the sake of health. Using his own research and experiences throughout the world, the author recounts how and why humans evolved to walk, run, dig, and do other necessary and rewarding physical activities while avoiding needless exertion. Drawing on insights from biology and anthropology, the author suggests how we can make exercise more enjoyable, rather that shaming and blaming people for avoiding it
Download or read book Chemical Warfare Agents written by Timothy T. Marrs and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Warfare Agents, Second Edition has been totally revised since the successful first edition and expanded to about three times the length, with many new chapters and much more in-depth consideration of all the topics. The chapters have been written by distinguished international experts in various aspects of chemical warfare agents and edited by an experienced team to produce a clear review of the field. The book now contains a wealth of material on the mechanisms of action of the major chemical warfare agents, including the nerve agent cyclosarin, formally considered to be of secondary importance, as well as ricin and abrin. Chemical Warfare Agents, Second Edition discusses the physico-chemical properties of chemical warfare agents, their dispersion and fate in the environment, their toxicology and management of their effects on humans, decontamination and protective equipment. New chapters cover the experience gained after the use of sarin to attack travellers on the Tokyo subway and how to deal with the outcome of the deployment of riot control agents such as CS gas. This book provides a comprehensive review of chemical warfare agents, assessing all available evidence regarding the medical, technical and legal aspects of their use. It is an invaluable reference work for physicians, public health planners, regulators and any other professionals involved in this field. Review of the First Edition: "What more appropriate time for a title of this scope than in the post 9/11 era? ...a timely, scholarly, and well-written volume which offers much information of immense current and...future benefit." —VETERINARY AND HUMAN TOXICOLOGY
Download or read book The Effects of Temperature and Humidity on the Inflammatory Response During Aerobic Exercise written by Kylene Boka and published by . This book was released on 2018 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat illness is potentially life-threatening and poses an occupational hazard for firefights and military personnel who have to exert themselves in hot, humid environments. The purpose of this study was to examine how circulating concentrations of IL-6, IL-10, IL-1ra, and IL-1[beta] responded to temperature and humidity during aerobic exercise. Twelve college-age men completed six experimental trials: a VO2max test, and cycling in five conditions: 5oC/passive humidity (LTLH), 22oC/45% humidity (MTMH), 22oC/70% humidity (MTHH), 35oC/20% humidity (HTLH), and 35oC/45% (HTMH). The environmental trials involved cycling for 60 minutes at 60% VO2max, resting for 15 minutes, cycling at 90% VO2max until exhaustion (TTE), then recovering for 60 minutes in the same temperature condition. Blood was obtained prior to exercise (PRE), after 60 minutes of cycling (60), after the TTE (90), and after recovery (REC). Blood was analyzed for serum levels of IL-6, IL-10, IL-1ra, and IL-1[beta]. There was a time effect for IL-6, IL-10, and IL-1ra in all conditions except LTLH. The increases in IL-6 were during exercise, at 60 and 90. For IL-10 and IL-1ra, the increases were at 90 and REC, respectively. The increases in IL-6 and IL-1ra were enhanced in HTLT and HTMH. For IL-1[beta], there was only a time effect at LTLH. The IL-6 response indicates an inflammatory response to exercise that is enhanced in the heat. The delayed response of IL-10 and IL-1ra and the lack of response of IL-1[beta] in the heat, indicates that the exercise-induced anti-inflammatory response outweighs the pro-inflammatory response to heat.
