Download or read book Orthopaedic Biomechanics written by Beth A. Winkelstein and published by CRC Press. This book was released on 2012-12-18 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review of the current knowledge of orthopaedic biomechanics across all tissues in the musculoskeletal system, at all size scales, and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopedic tissue types followed by the most-relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology and applied engineering approaches. With contributions from leaders in the field, the book presents state-of-the-art findings, techniques, and perspectives. Much of orthopaedic, biomechanical, and biomedical engineering research is directed at the translational capabilities for the "real world". Addressing this from the perspective of diagnostics, prevention, and treatment in orthopaedic biomechanics, the book supplies novel perspectives for the interdisciplinary approaches required to translate orthopaedic biomechanics to today’s real world.

Download or read book Osteoporosis written by Robert Marcus and published by Academic Press. This book was released on 2007-11-08 with total page 1987 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 percent continuing to make osteoporosis a hot topic in medicine. This newest edition covers everything from basic anatomy and physiology to diagnosis, management and treatment in a field where direct care costs for osteoporitic fractures in the U.S. reach up to $18 billion each year.NEW TO THIS EDITION:*Recognizes the critical importance of the Wnt signaling pathway for bone health *Incorporates new chapters on osteocytes, phosphatonins, mouse genetics, and CNS and bone *Examines essential updates on estrogen prevention and treatment and the recent results from the WHI *Discusses the controversial topics of screening and clinical trial design for drug registration *Includes essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, and parathyroid hormone * Offers critical reviews of reproductive and hormonal risk factors, ethnicity, nutrition, therapeutics, management, and economics comprising a tremendous wealth of knowledge in a single source not found elsewhere

Download or read book Marcus and Feldman s Osteoporosis written by David W. Dempster and published by Academic Press. This book was released on 2020-10-08 with total page 1950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. - Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents - Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis - Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

Download or read book Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System written by Z Jin and published by Elsevier. This book was released on 2014-05-05 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System reviews how a wide range of materials are modelled and how this modelling is applied. Computational modelling is increasingly important in the design and manufacture of biomedical materials, as it makes it possible to predict certain implant-tissue reactions, degradation, and wear, and allows more accurate tailoring of materials' properties for the in vivo environment. Part I introduces generic modelling of biomechanics and biotribology with a chapter on the fundamentals of computational modelling of biomechanics in the musculoskeletal system, and a further chapter on finite element modelling in the musculoskeletal system. Chapters in Part II focus on computational modelling of musculoskeletal cells and tissues, including cell mechanics, soft tissues and ligaments, muscle biomechanics, articular cartilage, bone and bone remodelling, and fracture processes in bones. Part III highlights computational modelling of orthopedic biomaterials and interfaces, including fatigue of bone cement, fracture processes in orthopedic implants, and cementless cup fixation in total hip arthroplasty (THA). Finally, chapters in Part IV discuss applications of computational modelling for joint replacements and tissue scaffolds, specifically hip implants, knee implants, and spinal implants; and computer aided design and finite element modelling of bone tissue scaffolds. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and mechanical engineers, and those in academia. - Covers generic modelling of cells and tissues; modelling of biomaterials and interfaces; biomechanics and biotribology - Discusses applications of modelling for joint replacements and applications of computational modelling in tissue engineering

Download or read book Fundamentals of Fracture Mechanics written by John Frederick Knott and published by Gruppo Italiano Frattura. This book was released on 1973 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition

Download or read book Biologic Foundations for Skeletal Tissue Engineering written by Ericka Bueno and published by Springer Nature. This book was released on 2022-05-31 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering research for bone and joint applications entails multidisciplinary teams bringing together the needed expertise in anatomy, biology, biochemistry, pathophysiology, materials science, biomechanics, fluidics, and clinical and veterinary orthopedics. It is the goal of this volume to provide students and investigators who are entering this exciting area with an understanding of the biologic foundations necessary to appreciate the problems in bone and cartilage that may benefit from innovative tissue engineering approaches. This volume includes state-of-the-art information about bone and cartilage physiology at the levels of cell and molecular biology, tissue structure, developmental processes, their metabolic and structural functions, responses to injury, mechanisms of post-natal healing and graft incorporation, the many congenital and acquired disorders, effects of aging, and current clinical standards of care. It reviews the strengths and limitations of various experimental animal models, sources of cells, composition and design of scaffolds, activities of growth factors and genes to enhance histogenesis, and the need for new materials in the context of cell-based and cell-free tissue engineering. These building blocks constitute the dynamic environments in which innovative approaches are needed for addressing debilitating disorders of the skeleton. It is likely that a single tactic will not be sufficient for different applications because of variations in the systemic and local environments. The realizations that tissue regeneration is complex and dynamic underscore the continuing need for innovative multidisciplinary investigations, with an eye to simple and safe therapies for disabled patients. Table of Contents: Introduction / Structure and Function of Bone and Cartilage Tissue / Development / Responses to Injury and Grafting / Clinical Applications for Skeletal Tissue Engineering / Animal Models / Tissue Engineering Principles for Bone and Cartilage / Perspectives

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1972 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Aging Skeleton written by Clifford Rosen and published by Elsevier. This book was released on 1999-08-19 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics. - Covers all aspects of the aging skeleton in one comprehensive volume - Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass - Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton - Reviews current therapeutic approaches and methods - Written by internationally renowned authors and edited by leaders in the field - Is the only book available on this subject

Download or read book Skeletal Aging and Osteoporosis written by Matthew J. Silva and published by Springer Science & Business Media. This book was released on 2012-08-30 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

Download or read book The Essentials of Charcot Neuroarthropathy written by Claude Pierre-Jerome and published by Elsevier. This book was released on 2022-05-11 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Essential Charcot Neuroarthropathy: Biomechanics, Pathophysiology, and MRI Findings provides a comprehensive analysis of Charcot neuroarthropathy (or Charcot Foot) in diabetic patients. All aspects are covered, including epidemiology, biomechanics, pathophysiology, socioeconomic impacts, radiological findings, and differential diagnosis, with an emphasis on MRI. Chapters address the challenges of pre-and-post surgical management of Charcot neuroarthropathy and the role of unconventional imaging modalities in diagnosis. The book presents an analysis of the normal biomechanics of the ankle and foot, the biomechanical derangements of the ankle-foot unit (including abnormal gait) caused by diabetes Type II, and more. Finally, there is also a reference of the pathophysiology of diabetes-induced peripheral neuropathy and its direct link with the development of Charcot neuroarthropathy foot. Diabetes-induced Charcot foot is frequently misunderstood, misinterpreted and misdiagnosed which can lead to confusion and detrimental management with reported high morbidity. - Presents a clear differentiation of Charcot neuroarthropathy with other conditions such as osteoarthritis, gout, psoriasis, rheumatoid arthritis, the Madura foot, and others - Provides a state-of-art catalogue of all radiological features of Charcot neuroarthropathy with MRI - Describes the pre-and post-surgical procedures used for the management of Charcot neuroarthropathy and their socioeconomic impacts - Includes MRI color images of soft tissue damages for ease of understanding

Download or read book Modeling of Biological Materials written by Francesco Mollica and published by Springer Science & Business Media. This book was released on 2007-12-31 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique collection highlights the central role played by modeling in general, and the modeling of mechanical considerations that have an effect on living matter. The volume collects several survey papers by actively working specialists, dealing with some of the most important problems – both theoretical and practical – in biomechanics. Written in a user-friendly style, these papers clearly explain both the biomedical and mechanical backgrounds associated with complex phenomena. This book may be used in interdisciplinary introductory courses covering various biomechanical topics for graduate students in applied mathematics, engineering, and biomedicine.

Download or read book Internal Fixation in Osteoporotic Bone written by Yuehuei An and published by Thieme. This book was released on 2011-01-01 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis affects 28 million people in the United States alone. The need for stable internal fixation of this type of bone is paramount. Metabolic bone diseases, such as osteoporosis, osteomalacia, hyperparathyroidism, and Paget's disease, are usually associated with osteoporotic or soft skeleton, especially in the elderly patient. Orthopedic procedures in elderly patients are costly and with the increasing age of the population these costs will continue to escalate. Great challenges are often encountered when internal fixation is needed for fractures or osteotomies in osteoporotic bone. This book is designed to present both current clinical techniques and cutting-edge knowledge in pre-clinical research on the internal fixation of osteoporotic bone.

Download or read book Medical Image Analysis and Informatics written by Paulo Mazzoncini de Azevedo-Marques and published by CRC Press. This book was released on 2017-11-23 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the development of rapidly increasing medical imaging modalities and their applications, the need for computers and computing in image generation, processing, visualization, archival, transmission, modeling, and analysis has grown substantially. Computers are being integrated into almost every medical imaging system. Medical Image Analysis and Informatics demonstrates how quantitative analysis becomes possible by the application of computational procedures to medical images. Furthermore, it shows how quantitative and objective analysis facilitated by medical image informatics, CBIR, and CAD could lead to improved diagnosis by physicians. Whereas CAD has become a part of the clinical workflow in the detection of breast cancer with mammograms, it is not yet established in other applications. CBIR is an alternative and complementary approach for image retrieval based on measures derived from images, which could also facilitate CAD. This book shows how digital image processing techniques can assist in quantitative analysis of medical images, how pattern recognition and classification techniques can facilitate CAD, and how CAD systems can assist in achieving efficient diagnosis, in designing optimal treatment protocols, in analyzing the effects of or response to treatment, and in clinical management of various conditions. The book affirms that medical imaging, medical image analysis, medical image informatics, CBIR, and CAD are proven as well as essential techniques for health care.

Download or read book Vitamin D written by David Feldman and published by Academic Press. This book was released on 2011-05-12 with total page 2190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D, a steroid hormone, has mainly been known for its effects on bone and osteoporosis. The current therapeutic practices expand into such markets as cancer research, pediatrics, nephrology, dermatology, immunology, and genetics. This 3e includes over 100 chapters covering everything from chemistry and metabolism to mechanisms of action, diagnosis and management, new analogs, and emerging therapies. This complete reference works is a must-have resource for anyone working in endocrinology, osteology, bone biology, or cancer research.

Download or read book Dental Implant Prosthetics E Book written by Carl E. Misch and published by Elsevier Health Sciences. This book was released on 2014-04-01 with total page 1009 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, Dental Implants Prosthetics, 2nd Edition helps you advance your skills and understanding of implant prosthetics. Comprehensive coverage includes both simple and complicated clinical cases, with practical guidance on how to apply the latest research, diagnostic tools, treatment planning, implant designs, materials, and techniques to provide superior patient outcomes. - Treatment supported by clinical evidence equips students with a more targeted evidence-based approach to patient procedures. - NEW! Emphasis on treatment planning helps decrease the number of visits while providing effective, long-term results for the patient. - NEW! Focus on the patient presentation offers the latest treatment options for bone harvesting, restoration and recovery. - NEW! Original illustrations and photos highlight and clarify key clinical concepts and techniques.

Download or read book Biomechanical Systems Technology A 4 volume Set 3 Muscular Skeletal Systems written by Cornelius T Leondes and published by World Scientific. This book was released on 2009-02-02 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of rapid developments in computer technology and computational techniques, advances in a wide spectrum of technologies, coupled with cross-disciplinary pursuits between technology and its application to human body processes, the field of biomechanics continues to evolve. Many areas of significant progress include dynamics of musculoskeletal systems, mechanics of hard and soft tissues, mechanics of bone remodeling, mechanics of blood and air flow, flow-prosthesis interfaces, mechanics of impact, dynamics of man-machine interaction, and more. Thus, the great breadth and significance of the field in the international scene require a well integrated set of volumes to provide a complete coverage of the exciting subject of biomechanical systems technology. World-renowned contributors tackle the latest technologies in an in-depth and readable manner.