Download or read book Animal and Translational Models for CNS Drug Discovery Psychiatric Disorders written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-17 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the first volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, and is also available for purchase individually. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Psychiatric Disorders is available for purchase individually.
Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.
Download or read book Forthcoming Books written by Rose Arny and published by . This book was released on 1998 with total page 1578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Narratology written by Joela Jacobs and published by MDPI. This book was released on 2020-12-15 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Narratology interrogates what it means to narrate, to speak—speak for, on behalf of—and to voice, or represent life beyond the human, which is in itself as different as insects, bears, and dogs are from each other, and yet more, as individual as a single mouse, horse, or puma. The varied contributions to this interdisciplinary Special Issue highlight assumptions about the human perception of, attitude toward, and responsibility for the animals that are read and written about, thus demonstrating that just as “the animal” does not exist, neither does “the human”. In their zoopoetic focus, the analyses are aware that animal narratology ultimately always contains an approximation of an animal perspective in human terms and terminology, yet they make clear that what matters is how the animal is approximated and that there is an effort to approach and encounter the non-human in the first place. Many of the analyses come to the conclusion that literary animals give readers the opportunity to expand their own points of view both on themselves and others by adopting another’s perspective to the degree that such an endeavor is possible. Ultimately, the contributions call for a recognition of the many spaces, moments, and modes in which human lives are entangled with those of animals—one of which is located within the creative bounds of storytelling.
Download or read book Large Animal Internal Medicine written by Bradford P. Smith and published by Elsevier Health Sciences. This book was released on 2019-05-21 with total page 2279 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody’s Core Titles® 2024 with "Essential Purchase" designation in Veterinary Medicine** Utilize a problem-oriented approach to the diagnosis of diseases of horses, cattle, sheep, and goats. Large Animal Internal Medicine, 6th Edition covers the diagnosis and management of disease in both ruminant and equine internal medicine. As the first veterinary internal medicine text to use a problem-based approach, it offers discussions of over 150 clinical signs and manifestations, as well as comprehensive coverage of laboratory and diagnostic testing. New to this edition is a versatile online reference platform and coverage of conditions that exist in Europe, Central and South America, Australia, and New Zealand. In addition, thoroughly revised and updated content includes new vaccines and vaccination protocols; the most current laboratories for DNA, genetic, and PCR testing; and colostrum supplements and replacers. It’s everything you need to stay up to date with the latest information on preventing and treating disease in large animals. Discussions of over 150 clinical signs or manifestations of disease provide you with a problem-based approach to diagnosis based on what you’ve observed and what laboratory tests reveal. Causes of Presenting Signs boxes offer quick access to the common, less common, and uncommon diseases associated with manifestations or signs of disease. Causes of Abnormal Laboratory Values boxes highlight the possible interpretations of abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. More than 200 expert authors contribute information in their areas of expertise for the most current, authoritative information on each topic. NEW! Expert Consult platform provides a versatile digital resource including bonus content, useful references, and videos to meet the needs of practicing equine and large animal veterinarians. NEW! Global conditions of importance are covered, including those previously not discussed, that exist in Europe, Central and South America, Australia, and New Zealand. NEW! Coverage of emerging and re-emerging diseases includes the new pathogen discovery. NEW! Assessment of vaccination status and susceptibility to infection discusses how antibody titers can predict protection for some pathogens. NEW! Description of epigenetics and metagenomics provides detailed coverage of these emerging areas of interest. NEW! Table of zoonoses obtained from large animals includes symptoms and disinfection needs. NEW! Videos demonstrate how to perform ultrasound imaging on an equine and cow abdomen clearly showing where to position the probe, and what depth to use for scans of the kidneys, liver, and bowel. NEW! Coverage of genetic disorders, Hydrocephalus in Fresians and Pulmonary hypoplasia with Anasarca in Dexter cattle help you to treat these disorders. NEW! Extensively updated content clarifies the latest research and clinical findings on the West Nile Virus, therapeutic drug monitoring, muscle disorders, GI microbiota, the genetic basis for Immune-mediated myositis in Quarter Horses, discoveries in antimicrobial drugs, anthelmintic, and vaccines, and more!
Download or read book Population Genetics Quantitative Genetics and Animal Improvement written by Michael P. H. Stumpf and published by . This book was released on 2005 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Who s who in America written by and published by . This book was released on 1912 with total page 2658 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Master Index to Summaries of Children s Books written by Eloise S. Pettus and published by Metuchen, N.J. : Scarecrow Press. This book was released on 1985 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-part index to summaries of children's books located in bibliographies, children's literature textbooks, and books of activities helps professionals keep current by directing them to the locations of summaries of over 18,000 titles in the 86 books analyzed.
Download or read book Blown Away Read Aloud by Paul Panting written by Rob Biddulph and published by HarperCollins UK. This book was released on 2014-08-28 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a read-along edition with audio synced to the text. Meet a fearless blue penguin on an unexpected journey, from the bestselling Rob Biddulph, creator of the internet sensation #DrawWithRob!
Download or read book A Dictionary of the Otchipwe Language Explained in English written by Frederic Baraga and published by . This book was released on 1853 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frequency Tables to be Used in Scoring the Rorschach Ink blot Test written by Marguerite Rosenberg Hertz and published by . This book was released on 1936 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Children s Books in Print 2007 written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Kingdom written by and published by . This book was released on 1919 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A I written by James Orchard Halliwell-Phillipps and published by . This book was released on 1855 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Sediment Relations written by Peter L. McCall and published by Springer. This book was released on 1982-09 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Annual Report of the Minister of Agriculture and Food written by Ontario. Dept. of Agriculture and Food and published by . This book was released on 1901 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Sediment Relations written by Peter McCall and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
