Download or read book Anhedonia Preclinical Translational and Clinical Integration written by Diego A. Pizzagalli and published by Springer Nature. This book was released on 2022-08-08 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
Download or read book Obsessive Compulsive Disorder written by Christopher Pittenger and published by Oxford University Press. This book was released on 2017 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obsessive-compulsive disorder (OCD) affects one person in 40 and can cause great suffering. This volume provides the first comprehensive summary of our understanding of this enigmatic condition, summarizing current work ranging from genetics and neurobiology through cognitive psychology, treatment, personal experiences, and societal implications
Download or read book Anhedonia A Comprehensive Handbook Volume I written by Michael S. Ritsner and published by Springer. This book was released on 2014-07-08 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive two-volume collection on anhedonia, a disorder that played an important role in psychopathology theories at the beginning of the twentieth century. Anhedonia is a condition in which the capacity of pleasure is partially or completely lost, and it refers to both a personality trait, and a “state symptom” in various neuropsychiatric and physical disorders. It has a putative neural substrate, originating in the dopaminergic mesolimbic and mesocortical reward circuit. Over the past three decades cognitive psychology and behavioral neuroscience have expanded our understanding of anhedonia and other reward-related processes. The aim of this new two-volume collection on anhedonia is to highlight the contributions of eminent scientists in this field as well as to provide readers with comprehensive accounts of recent developments as perceived by the authors. This monograph is divided into five parts. Volume I contains parts one and two (Conceptual Issues and Neurobiological Advances) including 14 chapters that serve as an introduction and overview of conceptual issues. Volume II contains three parts (Anhedonia in Psychotic Disorders, Anhedonia in Mood and Personality Disorders, and Anhedonia in Neurological and Physical Disorders) including 15 chapters that provide an overview of the construct, measurement of anhedonia in schizophrenia spectrum disorders, hedonic capacity and related factors in schizophrenia and schizoaffective disorder, anhedonia as an indicator of genetic liability for schizophrenia, and as a trait marker for depression, the role of an anhedonia in trauma-related disorders, anorexia nervosa, stress-induced eating disorders, schizotypal traits and risk of suicide. This book will be of interest to a broad spectrum of readers including psychiatrists, psychologists, neurologists, neuroscientists, endocrinologists, pharmacologists, general practitioners, geriatricians, graduate students, and health care providers in the fields of mental health.
Download or read book Next Generation Antidepressants written by Chad E. Beyer and published by Cambridge University Press. This book was released on 2010-05-20 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization defines depression as a primary contributor to the global burden of disease and predicts it will become the second leading cause of death by 2020. The need to develop effective therapies has never been so pressing. Current antidepressant drugs have several limitations. This 2010 book looks at the future of mood-disorder research, covering the identification of new therapeutic targets, establishing new preclinical models, new medicinal chemistry opportunities, and fostering greater understanding of genetic influences. These strategies are likely to help build a better picture of the disease process, and lead to new opportunities for patient stratification and treatment. The ultimate goal for this strand of research is to develop more personalized and effective treatments for this chronic and debilitating condition. This is essential reading for all those involved in psychopharmacologic drug development, and mental health clinicians seeking a preview of discoveries soon to influence their practice.
Download or read book Clinical Staging in Psychiatry written by Patrick D. McGorry and published by Cambridge University Press. This book was released on 2019-08-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.
Download or read book Why Good Sex Matters written by Nan Wise and published by Houghton Mifflin. This book was released on 2020-01-28 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: A sex therapist and neuroscientist describes anhedonia, the inability to feel a satisfactory amount of pleasure--and provides the pathway back to fully enjoying sex, food, time with family and friends, and other pastimes, while also staving off depression, anxiety, and addiction.
Download or read book Clinical Psychiatry Essentials written by Laura Weiss Roberts and published by Lippincott Williams & Wilkins. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinically relevant and visually accessible, Clinical Psychiatry Essentials is tailored specifically to meet the needs of today's students. Easy to read and use, it provides an introduction to the field of psychiatry and features a wealth of learning tools to maximize comprehension. Each chapter integrates clinical case scenarios, clinical pearls, and study questions, making this an excellent resource for course study and exam preparation. The book addresses core competency issues, including communication skills, system-based aspects of care, and professionalism and focuses on innovative areas of psychiatry including patient-centered care practices and new therapies. A companion Website provides access to the fully searchable text.
Download or read book Understanding Depression written by Yong-Ku Kim and published by Springer. This book was released on 2018-01-02 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression, the clinical manifestations, and the development of more effective treatments. This second volume is devoted specifically to clinical and management issues. Readers will find detailed information on a wide range of frequently encountered and more complicated clinical presentations, with examination of risk factors and links to other conditions. Diagnostic aspects, including progress toward biological classification and the role of neuroimaging, are explored. Current trends in therapy are examined at length, drawing on the latest evidence and covering not only antidepressant medications but also the roles of neurostimulation, combined pharmacotherapy and psychotherapy, mindfulness-based cognitive therapy, and complementary and alternative medicine. The companion volume is dedicated to the underlying biomedical and neurobiological basis of depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.
Download or read book Clinical Handbook for the Management of Mood Disorders written by J. John Mann and published by Cambridge University Press. This book was released on 2013-05-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-stop evidence-based guide to the management of all types of mood disorders.
Download or read book Handbook of Reward and Decision Making written by Jean-Claude Dreher and published by Academic Press. This book was released on 2009-06-04 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...). Comprehensive coverage of approaches to studying reward and decision making, including primate neurophysiology and brain imaging studies in healthy humans and in various disorders, genetic and hormonal influences on the reward system and computational models. Covers clinical implications of process dysfunction (e.g., schizophrenia, Parkinson's disease, eating disorders, drug addiction, pathological gambling) Uses multiple levels of analysis, from molecular mechanisms to neural systems dynamics and computational models. " This is a very interesting and authoritative handbook by some of the most outstanding investigators in the field of reward and decision making ", Professor Edmund T. Rolls, Oxford Center for Computational Neuroscience, UK
Download or read book Positive Affect Treatment for Depression and Anxiety written by Michelle G. Craske and published by Oxford University Press. This book was released on 2022 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book culminates a career-long search for justice. I felt it important to understand what it is and where it came from as a feature of human society, of human life. I wound up in a department of education, perhaps quite fortuitously, for education enabled me to examine how experiences of justice or injustice in various educational settings shape children and young people's values, behaviors, and chances for living a decent future life"--
Download or read book Perfectly Hidden Depression written by Margaret Robinson Rutherford and published by New Harbinger Publications. This book was released on 2019-11-01 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: When your life looks perfect, but you’re silently falling apart… If you were raised to believe that painful emotions are a sign of weakness, or if being vulnerable has always made you feel unsafe, then you may have survived by creating a perfect-looking life—a life where you appear to be successful, engaged, and always there for others. The problem? You’re filled with self-criticism and shame, and you can’t allow yourself to express fear, anger, loss, or grief. You recognize something is wrong, but you’re not sure what exactly—only that you feel trapped and alone. If this sounds like you, you may have perfectly hidden depression (PHD). With this compassionate guide, you’ll begin the process of understanding your perfectionism, identifying destructive beliefs, and connecting with emotions suppressed for far too long. You’ll also find tangible tips for quieting that critical inner voice, and powerful strategies for coping with difficult feelings. Most importantly, you’ll learn that asking for help isn’t a sign of weakness, but a sign of strength. If you’re ready to stop hiding and start healing, this groundbreaking book will guide you—every imperfect step of the way.
Download or read book Antidepressants written by Olivier Berend and published by BoD – Books on Demand. This book was released on 2019-11-20 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones, there is still much room for improvement. "Real" antidepressants, defined as those that "repair" or "improve" the depression-causing mechanism in the brains of depressed patients, have yet to be identified. This book presents current research on depression and antidepressants, including use of antidepressants in alcohol use disorders and pregnancy, treatment-resistant depression, and development of potential new medications.
Download or read book Behavioral Neuroscience of Motivation written by Eleanor H. Simpson and published by Springer. This book was released on 2016-05-11 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the current status of research in the neurobiology of motivated behaviors in humans and other animals in healthy condition. This includes consideration of the psychological processes that drive motivated behavior and the anatomical, electrophysiological and neurochemical mechanisms which drive these processes and regulate behavioural output. The volume also includes chapters on pathological disturbances in motivation including apathy, or motivational deficit as well as addictions, the pathological misdirection of motivated behavior. As with the chapters on healthy motivational processes, the chapters on disease provide a comprehensive up to date review of the neurobiological abnormalities that underlie motivation, as determined by studies of patient populations as well as animal models of disease. The book closes with a section on recent developments in treatments for motivational disorders.
Download or read book The Cognitive Behavioral Workbook for Depression written by William J. Knaus and published by New Harbinger Publications. This book was released on 2012-06-01 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognitive behavioral therapy (CBT) is the most widely used treatment for depression for one simple reason: it works. The CBT program in this workbook has helped thousands of readers defeat the depressive thoughts and beliefs that keep them from enjoying life and feeling like themselves. Used alone or in conjunction with therapy, The Cognitive Behavioral Workbook for Depression delivers evidence-based tools you can confidently use to do better, feel better, and prevent depression from coming back. Through a series of worksheets and exercises, you’ll evaluate your depression and learn key skills for overcoming it. Once you have your depression symptoms under control, you will appreciate the additional information on preventing relapse that is special to this new edition. This workbook also includes twenty-five bonus tips from depression experts that can jump-start your recovery. Recommended by therapists nationwide, this workbook will help you bounce back from depression, one solid step at a time. Includes worksheets and exercises that will help you: • Move past the negative beliefs about yourself that keep you trapped in the depression cycle • Apply behavioral techniques that therapists use with their clients, such as activity scheduling • Discover effective ways to cope with feelings of stress, anxiety, and anger • Avoid procrastinating and learn to anchor the positive changes you make to maintain your progress “Chock-full of the ready-to-use strategies you will need to help you feel good again.” —Jon Carlson, PsyD, EdD, Distinguished Professor at Governors State University
Download or read book Bipolar Disorder From Neuroscience to Treatment written by Allan H. Young and published by Springer Nature. This book was released on 2021-03-29 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.
Download or read book Thrilled to Death written by Archibald D. Hart and published by Thomas Nelson. This book was released on 2007-09-30 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating exploration of the profound loss of pleasure in our daily lives and the seven steps for restoring it. Pleasure. We know what it feels like and many of us spend our days trying to experience it. But can too much pleasure actually be bad for us? Yes, says Dr. Archibald Hart, clinical psychologist and expert in behavorial psychology. Backed by recent brain-imaging research, Dr. Hart shares that to some extent, our pursuit of extreme and overstimulating thrills hijacks our pleasure system and robs us of our ability to experience pleasure in simple things. We are literally being thrilled to death. In this insightful book, Dr. Hart explores the stark rise in a phenomenon known as anhedonia, an inability to experience pleasure or happiness. Previously linked only to serious emotional disorders, anhedonia is now seen as a contributing factor in depression (specifically nonsadness depression) and in the growing number of people who complain of profound boredom. This emotional numbness and loss of joy are results of the overuse of our brain's pleasure circuits. In Thrilled to Death, Dr. Hart explains the processes of the brain's pleasure center, the damaging trends of overindulgence and overstimulation, the signs and problems of anhedonia, and the seven important steps we must take to recover our wonderful joy in living.
