Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Download or read book Mass Spectrometry for the Clinical Laboratory written by Hari Nair and published by Academic Press. This book was released on 2016-11-02 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Download or read book Analytical Mass Spectrometry Section written by William R. Shields and published by . This book was released on 1970 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report describes the advances in instrumentation and the research activities of the Smslytical Mass Spectrometry Section during the period July 1969 to June 1970.Advances in instrumentation include the construction of a computer controlled mass spectrometer with appropriate interconnecting components, power supplies with greatly increased stability and the utilization of a magnetic field control.Elements studied during this period include: B, Cu, Ag, Pb, T1, U, Pu, K, Rb, Ni and Mo.Mass spectrometric procedures are given for Pb, T1, U, K, Ni and Mo.Chemical procedures for the intercomparison of redox standards are also given.(Author).

Download or read book Mass Spectrometry Basics written by Christopher G. Herbert and published by CRC Press. This book was released on 2002-06-26 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides

Download or read book Mass Spectrometry written by James Barker and published by John Wiley & Sons. This book was released on 1999-02-02 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly updated second edition of the ACOL text on Mass Spectrometry gives a modern approach to those beginning to use or study mass spectrometry. Self assessment questions and solutions are included. Fundamentals and modern instrumental techniques are also covered in this book.

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

Download or read book Advances in Mass Spectrometry written by R. M. Elliott and published by Elsevier. This book was released on 2013-10-22 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Mass Spectrometry, Volume 2 documents the proceedings of a conference on mass spectrometry held in Oxford in September 1961. This compilation is categorized into six major topics — mass spectrometry in research; mass spectrometry of inorganic compounds; instruments and techniques; theory and correlation of mass spectra; mass spectra and analysis; and ionization and dissociation. Under these major topics, parts of the papers discussed include field ionization mass spectroscopy; initial kinetic energy discrimination effects in crossed-field ion sources; mass spectrometric study of CaO and Ta; and spark source mass spectrometry as an analytical technique. The book also covers discussions on initial energy of hydrocarbon fragment ions; determination of the structure of alkaloids by mass spectrometry; and application of a time-of-flight mass spectrometer to the examination of ion-molecule interactions. This volume is a useful reference to students and researchers conducting work on mass spectrometry.

Download or read book Mass Spectrometry written by Reg Davis and published by John Wiley & Sons. This book was released on 1987 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry has undergone a great deal of development as an empirical subject and many useful approaches to the analysis and identification of organic molecules have been developed without a detailed understanding of theory of ion behaviour. This is also the way in which the subject is usually approached and it is the tack adopted here. That does not mean to say that an understanding of ion behaviour is not important - it is, but that understanding is still being developed and this book is designed for those wishing to use mass spectrometry now.

Download or read book Mass Spectrometry written by Agnieszka Kraj and published by John Wiley & Sons. This book was released on 2008-12-01 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.

Download or read book Analytical Mass Spectrometry Section July 1966 to June 1967 written by William R. Shields and published by . This book was released on 1967 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report describes the advances in instrumentation and the research activities of the NBS Analytical Mass Spectrometry Selection.Advances in instrumentation include the construction of a multi-stage mass spectrometer, a high vacuum beam valve, a Z focussing lens, a re-designed collector, a filament degas chamber, and new equipment for sample drying.The new facilities at Gaithersburg are described.Elements studied during this period include: B, Cr, Pb, Rb, U, and Pu. Chemical procedures are given for B, Cr, Pb, and Pu; mass spectrometric procedures are given for B, Cr, Pb, Pu, Rb, and U.(Author).

Download or read book Analytical Mass Spectrometry Section Summary of Activities July 1968 to June 1969 written by William R. Shields and published by . This book was released on 1970 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: The report describes the advances in instrumentation and the research activities of the Analytical Mass Spectrometry Section during the period July 1968 to June 1969.Chemical and mass spectrometric procedures are described for the determinations of the absolute isotopic abundance ratios of natural rubidium, boron in a natural boric acid and a 10B enriched boric acid, and of uranium in six SRMs.Procedures are also described for the determination of trace amounts of copper and lead in steel, and silver, copper, boron and uranium in glass by isotope dilution mass spectrometry.(Author).

Download or read book Analytical Mass Spectrometry Section Instrumentation and Procedures for Isotopic Analysis written by W. A. Shields and published by . This book was released on 1966 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Download or read book Gas Chromatography and Mass Spectrometry written by Fulton G. Kitson and published by Academic Press. This book was released on 1996-08-30 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide provides, under one cover, a wealth of practical information designed to facilitate the effectiveness of the GC/MS user. Separation conditions for numerous compound types are provided along with derivatized and underivatized compounds. A section on how to interpret mass spectral data, an extensive correlation of ion masses and neutral losses with possible structures, and examples of mass spectra are provided to further aid structure determination. Also included are basic information on instrumentation, ionization methods, quantitation, tips on the operation of mass spectrometers, the best derivatization procedures for a variety of compound types, troubleshooting techniques, and a variety of other information found to be useful to the practicing user of GC/MS instrumentation. This guide would be immediately valuable to the novice as well as the experienced GC/MS user who may not have the breadth of experience covered in this book. Key Features * Condenses and organizes recent and essential information for new and experienced GC/MS users * Comprehensively indexed and referenced * Includes practical methods of analysis * Serves as a text reference for short practical courses on the subject

Download or read book Mass Spectrometry in Biopharmaceutical Analysis written by Igor A. Kaltashov and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-11-22 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals are a unique class of compounds due to their extreme structural complexity. The current text puts together a variety of the state‐of‐the art approaches that use mass spectrometry to evaluate various aspects of biopharmaceutical products ranging from monitoring stress‐related structural changes to their quantitation in pharmacokinetic studies.

Download or read book Trace Quantitative Analysis by Mass Spectrometry written by Robert K. Boyd and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style

Download or read book Introduction to Mass Spectrometry written by J. Throck Watson and published by John Wiley & Sons. This book was released on 2007-11-12 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction The mass spectrometer Mass spectrometry/mass spectrometry Inlet systems Strategies for data interpretation (other than fragmentation) Electron ionization Chemical ionization Electrospray ionization MALDI Gas chromatography/mass spectrometry Liquid chromatography/mass spectrometry Analysis of proteins and other biopolymers.