Download or read book Analysis of Quantal Response Data written by Byron J. T. Morgan and published by Springer. This book was released on 1990 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of Quantal Response Data written by Byron J.T. Morgan and published by CRC Press. This book was released on 2018-12-13 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes the standard methods as the starting point, and then describes a wide range of relatively new approaches and procedures designed to deal with more complicated data and experiments - including much recent research in the area. Throughout mention is given to the computing requirements - facilities available in large computing packages like BMDP, SAS and SPSS are also described.
Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-08-14 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
Download or read book Sequential Methods for the Analysis of Quantal Response Data written by John Richard Law and published by . This book was released on 1973 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantal Response Analysis in the Absence of a Zone of Mixed Results Using Data Augmentation written by and published by . This book was released on 2008 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantal response analysis is used to estimate the probability of a dichotomous response, e.g., complete penetration, as a function of a stimulus variable. Using maximum likelihood and the DiDonato-Janagin algorithm, estimates of the normal distribution parameters that underlie threshold stimulus levels are obtainable if a zone of mixed results is observed in the test data and if the average success-producing stimulus exceeds the average failure-producing stimulus. In the absence of a zone of mixed results, a method is proposed that utilizes data augmentation to estimate some parameter of interest, e.g., the probability of success at a specific stimulus level. This method generates artificial copies of the original data set of stimuli and responses and then adds a random noise component to each of the stimuli.
Download or read book Statistical Evaluation of Quantal Response Data written by J. °Ake Espmark and published by . This book was released on 1964 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantal Response Equilibrium written by Jacob K. Goeree and published by Princeton University Press. This book was released on 2016-06-28 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantal Response Equilibrium presents a stochastic theory of games that unites probabilistic choice models developed in psychology and statistics with the Nash equilibrium approach of classical game theory. Nash equilibrium assumes precise and perfect decision making in games, but human behavior is inherently stochastic and people realize that the behavior of others is not perfectly predictable. In contrast, QRE models choice behavior as probabilistic and extends classical game theory into a more realistic and useful framework with broad applications for economics, political science, management, and other social sciences. Quantal Response Equilibrium spans the range from basic theoretical foundations to examples of how the principles yield useful predictions and insights in strategic settings, including voting, bargaining, auctions, public goods provision, and more. The approach provides a natural framework for estimating the effects of behavioral factors like altruism, reciprocity, risk aversion, judgment fallacies, and impatience. New theoretical results push the frontiers of models that include heterogeneity, learning, and well-specified behavioral modifications of rational choice and rational expectations. The empirical relevance of the theory is enhanced by discussion of data from controlled laboratory experiments, along with a detailed users' guide for estimation techniques. Quantal Response Equilibrium makes pioneering game-theoretic methods and interdisciplinary applications available to a wide audience.
Download or read book A Bayesian Model for the Analysis of Quantal Response Data written by and published by . This book was released on 2003 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inference on the failure probabilities of ordered binomial trials conducted at M differing stress levels is considered. It is shown that a general joint prior may be constructed as a mixture of ordered M variate Dirichlet distributions, which possesses marginals of nearly arbitrary shapes. Posterior marginals at both observational and non-observational stresses are shown to consist of sums of beta distributions. Recursive relationships are developed that permit the rapid and exact computation of the posterior marginal distributions. The model is attractive for use in successive Bayesian analyses.
Download or read book Quantal Response Analysis of Some Biological Phenomena written by Jerome Senturia and published by . This book was released on 1974 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Model robust Quantal Regression written by Quinton Jacob Nottingham and published by . This book was released on 1995 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Use of Non Linear Regression Methods for Analysing Sensitivity and Quantal Response Data written by and published by . This book was released on 1965 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A great many special methods for the statistical analysis of sensitivity or quantal response data have been developed during the past century. This paper demonstrates that many of these techniques can be considered in the light of non-linear regression methods which have been made more tolerable in recent years with the prevalence of high-speed computers.
Download or read book Manual of Pharmacologic Calculations written by Ronald Tallarida and published by Springer. This book was released on 1984-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a collection of quantitative procedures in common use in we selected may be pharmacology and related disciplines. The procedures considered" core" since it is likely that all scientists who work with drugs will use these procedures at some time or another. By excluding very specialized topics, we managed to keep the size of the book small. thus making it handy reference-a handbook in the true sense. for quick Since many scientists and students now have access to electronic computers, of lower cost microcomputers is likely to increase com and since the advent we also included a computer program for each puter availability even further, procedure. * The user need not know computer programming since all necessary information needed to run the programs is included here. The manual is divided into two parts. In the first, the pharmacologic basis for the calculation is briefly stated for each of the procedures (numbered 1 through 33). Then the appropriate equations (formulas) are given and an example of each calculation is provided. For each procedure, the discussion of theory and illustration of the calculation are brief and self-contained. With the tables in the Appendix and a pocket calculator, all of the calculations can be done without reference to any other source. It is recommended that the pro cedure and sample calculation be read and understood before going to the automated "magic" of the computer program in Part II.
Download or read book Recurrent Events Data Analysis for Product Repairs Disease Recurrences and Other Applications written by Wayne B. Nelson and published by SIAM. This book was released on 2003-01-01 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival data consist of a single event for each population unit, namely, end of life, which is modeled with a life distribution. However, many applications involve repeated-events data, where a unit may accumulate numerous events over time. This applied book provides practitioners with basic nonparametric methods for such data.
Download or read book An Introduction to the Interpretation of Quantal Responses in Biology written by Paul Soames Hewlett and published by . This book was released on 1979 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: The typical dose-response cure. The probit and similar transformations. The logit transformation. Calculations in probit analysis. Calculations in logit analysis. Quantal responses to mixtures of drugs. Dose-response curves from heterogeneous populations and detection of resistance in insects. Time and response. The general nature of quantal response.
Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
Download or read book Dose Response Analysis Using R written by Christian Ritz and published by CRC Press. This book was released on 2019-07-19 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development. Key Features: Provides a practical and comprehensive overview of dose-response analysis. Includes numerous real data examples to illustrate the methodology. R code is integrated into the text to give guidance on applying the methods. Written with minimal mathematics to be suitable for practitioners. Includes code and datasets on the book’s GitHub: https://github.com/DoseResponse. This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed.
Download or read book Estimation and Confidence Intervals for Quantal Response Or Sensitivity Data written by Guy Burton Seibert (Jr) and published by . This book was released on 1970 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: If different levels of stimuli are applied and then counts are made of the number reacting and not-reacting to the stimuli, a sensitivity analysis is usually the best analysis to be applied. Sensitivity analysis may be used to determine the probability of destroying a target with different size bombs, without the necessity of actually having data on all the different sizes. It may also be used in determining the effect of a drug on a patient or the effect of polution on a body of water. This paper is concerned with a generalized model for sensitivity analysis based on the Burr distribution. This generalization gives a model that will fit quite well data that comes from probit or logit models, but also covers many additional situations that the probit or logit models would not fit. A FORTRAN IV program is included for doing the analysis on a computer. Confidence intervals for any quantile are also given. (Author).
