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Book Postlabelling Methods for Detection of DNA Adducts

Download or read book Postlabelling Methods for Detection of DNA Adducts written by D. H. Phillips and published by . This book was released on 1993 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book devoted to postlabelling methods, an important new analytical methodology. Postlabelling methods have a wide range of applications: these include studies of pathways of metabolic activation of chemical carcinogens, studies of oxidative damage to DNA, monitoring occupational exposure to carcinogens, the association between DNA adducts and disease, the possible role of DNA adducts in hormonal carcinogenesis and aging, the study of complex environmental mixtures of carcinogens and monitoring the effects of such mixtures on various ecosystems. Because of the high sensitivity of the postlabelling methods, they can also be applied to humans who are exposed to low levels, and many groups have concentrated their efforts towards the evaluation of adduct formation in relation to exposure and identification of cancer causing agents.

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Biological Monitoring

    Book Details:
  • Author : Jurgen Angerer
  • Publisher : John Wiley & Sons
  • Release : 2008-01-08
  • ISBN : 3527621032
  • Pages : 211 pages

Download or read book Biological Monitoring written by Jurgen Angerer and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the invitation of the Deutsche Forschungsgemeinschaft (DFG), a round-table discussion was held on 9 and 10 March 2000, dealing with future possibilities for biomonitoring in occupational and environmental medicine. Biomonitoring has reached a high standard in Germany over the past 30 years, not least due to the fact that the results of the Senate commission on materials hazardous to health at the workplace have been directly implemented as part of the jurisdiction relating to occupational safety. This book combines the expertise gathered from various areas within toxicology, occupational medicine, immunology and human genetics, right up to analysis and epidemiology. Throughout, the focus is on comprehensively determining the diagnostic validity of cytogenetic parameters as well as biochemical and biological effect markers for the prevention of illnesses resulting from harmful substances. Thus, the discussion allowed an initial exchange of ideas, pointing to future research, so as to maintain Germany's leading role in this important and rapidly expanding field. "...provides an excellent tutorial on the use of biological monitoring in occupational and environmental medicine...should be read by everyone involved with exposure analysis." - Chemical Chemistry

Book ICRDB Cancergram

Download or read book ICRDB Cancergram written by and published by . This book was released on 1985 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Toxicology of industrial compounds

Download or read book Toxicology of industrial compounds written by H. Thomas and published by CRC Press. This book was released on 1995-11-21 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: A large number of chemical compunds are constantly being introduced and produced, both to assist and ease modern human life. Among these chemicals, industrial compounds represent a particular fraction of chemicals which are not intended for use in biological systems, but to which humans may be accidently exposed, whether in the workplace, by product application, or via the environment. Industrial chemicals, as opposed to pharmaceuticals and agrochemicals, are in many cases subjected only to a very basic examination of handling safety, and may lack further toxicity testing. This implies that essentially nothing is known about their bioavailability, metabolism, excretion and toxicological properties, unless problems arise.; Covering the investigation of industrial chemicals, this book focuses on their individual structure, biological fate, potential toxicity to mammals and the molecular mechanisms possibly underlying their adverse effects by highlighting the use and significance of experimental toxicology. Special emphasis is placed on mechanistic aspects in the safety assessment of industrial compounds, in addition to current regulatory and legal considerations.

Book IARC Scientific Publications

Download or read book IARC Scientific Publications written by and published by . This book was released on 1988 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Nucleic Acids Abstracts

Download or read book Nucleic Acids Abstracts written by and published by . This book was released on 1997 with total page 1158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Environmental Health Perspectives

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Methods for Detecting DNA Damaging Agents in Humans

Download or read book Methods for Detecting DNA Damaging Agents in Humans written by H. Bartsch and published by . This book was released on 1988 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors to this volume focus on the fact that while reliable and sensitive detection of characteristic molecular markers for human exposure to chemical carcinogens is no longer a barrier to further study, the evaluation of the risk of developing a tumor following such exposures remains a difficult problem. Methods by which human exposure to carcinogens has been detected are described, including immunoassay techniques, physico-chemical methods and post-labelling assays. A number of studies are then discussed in which molecular markers are being used to assess exposure to environmental, occupational and iatrogenic carcinogens, and to relate this information to the type or incidence of cancers that occur.

Book Special Reports

    Book Details:
  • Author : Robert Snyder
  • Publisher :
  • Release : 1993
  • ISBN :
  • Pages : 804 pages

Download or read book Special Reports written by Robert Snyder and published by . This book was released on 1993 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Biomarkers

Download or read book Biomarkers written by and published by . This book was released on 1996 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Journal of the National Cancer Institute

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1987 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Annual Report

    Book Details:
  • Author : University of California (System). Toxic Substances Research and Teaching Program
  • Publisher :
  • Release : 1992
  • ISBN :
  • Pages : 132 pages

Download or read book Annual Report written by University of California (System). Toxic Substances Research and Teaching Program and published by . This book was released on 1992 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Molecular Epidemiology

    Book Details:
  • Author : Paul A. Schulte
  • Publisher : Academic Press
  • Release : 2012-12-02
  • ISBN : 0323138578
  • Pages : 609 pages

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Book Chemical Abstracts

Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2364 pages. Available in PDF, EPUB and Kindle. Book excerpt: