Download or read book Amorphous Calcium Phosphate Based Bioactive Polymeric Composites written by and published by DIANE Publishing. This book was released on with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Amorphous Calcium Phosphate as Bioactive Filler in Polymeric Dental Composites written by Drago Skrtic and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: As biocompatible and osteo-inductive precursor to biological apatite formation, amorphous calcium phosphate (ACP) resorbs at the rate that closely coincides with the rate of new bone formation and is more osteo-conductive than its crystalline counterpart. In addition, in the oral environment, ACP intrinsically provides a protracted supply of the remineralizing calcium and phosphate ions needed for regeneration of mineral lost to tooth decay. These features make ACP composites a strong remineralizing tool at the site of caries attack. Our group has been on the forefront of the research on bioactive, remineralizing, polymeric ACP-based dental materials for over two decades. This entry describes methods for filler, polymer, and composite fabrication and a battery of physicochemical and biological tests involved in evaluation of ACP-based restoratives. Also presented is our most recent design of ACP remineralizing composites with added antimicrobial capability that shows promise for extended dental and, potentially, wider biomedical applications.
Download or read book Structural and Dynamical Studies of Acid mediated Conversion in Amorphous calcium phosphate Based Dental Composites written by and published by . This book was released on 2014 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our objective was to investigate the complex structural and dynamical conversion process of the amorphous-calcium-phosphate (ACP)-to-apatite transition in ACP based dental composite materials. Composite disks were prepared using zirconia hybridized ACP fillers (0.4 mass fraction) and photo-activated Bis-GMA/TEGDMA resin (0.6 mass fraction). We performed an investigation of the solution-mediated ACP-to-apatite conversion mechanism in controlled acidic aqueous environment with in situ ultra-small angle X-ray scattering based coherent X-ray photon correlation spectroscopy and ex situ X-ray diffraction, as well as other complementary techniques. We established that the ACP-to-apatite conversion in ACP composites is a two-step process, owing to the sensitivity to local structural changes provided by coherent X-rays. Initially, ACP undergoes a local microstructural rearrangement without losing its amorphous character. We established the catalytic role of the acid and found the time scale of this rearrangement strongly depends on the pH of the solution, which agrees with previous findings about ACP without the polymer matrix being present. In the second step, ACP is converted to an apatitic form with the crystallinity of the formed crystallites being poor. Separately, we also confirmed that in the regular Zr-modified ACP the rate of ACP conversion to hydroxyapatite is slowed significantly compared to unmodified ACP, which is beneficial for targeted slow release of functional calcium and phosphate ions from dental composite materials. Significantly, for the first time, we were able to follow the complete solution-mediated transition process from ACP to apatite in this class of dental composites in a controlled aqueous environment. A two-step process, suggested previously, was conclusively identified.
Download or read book Amorphous Calcium Phosphate Composites of a Phenylalanine based Poly ester Urea Poly 1 phe 6 written by Gabrielle Victoria Seifert and published by . This book was released on 2016 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical size bone defects are large defects that do not spontaneously heal over time and result in permanent non-union of the bone. These abnormalities can result from traumas, surgeries, and diseases. Surgical methods used to treat these defects include natural (autografts and allografts) and synthetic bone grafts. Autografts draw advantages from diminished immune response but suffer from complications during implantation as well as pain and cosmetic defects during removal. Allograft complications include rejection and infection. Infection can be minimized by sterile processing techniques, but this frequently leads to diminished mechanical properties post-processing. As a consequence of these limitations, synthetic bone grafts have drawn significant interest. Synthetic bone grafts include biodegradable polymers, metals, and ceramics. For example, poly(caprolactone) (PCL) and poly(L-lactic acid) (PLLA) are biodegradable polymers used widely for medical applications. These materials can be molded into any desired shape; however, they are unsuitable for load-bearing applications as a consequence of their poor mechanical properties post-processing. Bioceramics, such as amorphous calcium phosphate (ACP), benefit from their osteoconductive behavior but are too brittle for load-bearing applications. Combining the biodegradable polymers with bioceramics have shown increased mechanical properties in the composites. The goal of this study was to examine the resulting mechanical properties of combining an L-phenylalanine-based poly(ester urea) (PEU) with various amount of ACP. We hypothesize that adding ACP to the polymer will lead to enhanced mechanical properties compared to the pure polymer.
Download or read book Contemporary Topics about Phosphorus in Biology and Materials written by David Churchill and published by BoD – Books on Demand. This book was released on 2020-09-09 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a diverse set of topics regarding phosphorus chemistry, namely phosphates and closely related chemical systems. Divided into two sections, chapters cover such topics as phosphate dynamics and phosphates in biomaterials. This volume is a useful reference for scholars and researchers and will inspire readers to make future discoveries in the field.
Download or read book Calcium Phosphates in Biological and Industrial Systems written by Zahid Amjad and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Phosphates in Biological and Industrial Systems provides a comprehensive discussion on calcium phosphates in the diverse areas of their applications. The authors are all respected specialists in their particular fields, possessing wide knowledge and experience and able to analyze recent results and relate them to their respective areas of expertise. New information, as well as a review of current concepts, highlights the individual contributions. Due to the broad scope of the subject covered and the large number of contributions, this book is divided into three parts. Whilst each section contains a basic theme, there is a considerable overlapping of ideas and approaches. This reflects the excitement and interdisciplinary nature of investigations by researchers interested in dissimilar aspects of calcium phosphates. Considering the general interest in calcium phosphates, Calcium Phosphates in Biological and Industrial Systems is directed at an audience of researchers in the fields of biology, chemistry, dentistry, geology, chemical engineering, environmental engineering, and medicine. It will also be useful to technology-focused researchers in industry whose investigations might be related directly or indirectly to calcium phosphates.
Download or read book Processing and Properties of Bioactive Bioresorbable Polymer calcium Phosphate Composites for Orthopaedic Applications written by Samuel Isaac Jojo Wilberforce and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium phosphate Ceramics Bioresorbable Polymer Composite Biomaterials written by Dragan P. Uskoković and published by Institute of Technical Sciences of the Serbian Academy of Sciences and Arts. This book was released on 2007-10-01 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past several years, the accent of a number of scientific researches in the countries of the European Union, USA and Japan was focused on the field of biomaterials. Having the direct influence on the quality and longevity of human life, these researches receive significant funding. The bone tissue is an especially interesting subject of scientific research, as much for the frequent osteoporosis as for the formative nature of organism. Natural bone is mostly composed of nanostructural calcium phosphate (hydroxyapatite). Whether bone trauma was caused artificially or through illness, the number of reconstructions increases every year worldwide and thus the monetary investment into this field. Until now, numerous kinds of biomaterials were used for this purpose. Development of equipment and progress in characterization techniques and devices enabled an exponential development of new and advanced biomaterials’ synthesis. Many qualitative and quantitative content concepts and the organization of biomaterials on all structural levels were taken from nature. Biomaterials for the reconstruction of bone tissue, very similar to human tissue, in the form of composite blocks, injectable cements, nano-fillers, etc., were produced this way. Synthesis of calcium phosphate and hydroxyapatite, as well as the composite for the reconstruction of bone tissue, has been a significant research field of a section of Advanced Materials and Processes Department of the Institute of Technical Sciences of the Serbian Academy of Sciences and Arts (ITS SASA) from Belgrade for a number of years. Apart from a number of published scientific papers in leading international journals, lectures presented at the leading universities worldwide, several PhD dissertations defended at various faculties in the land, and several domestic patents, researchers have established the basis of the technological procedure and the production of small series of various products developed in their laboratory. These researches have very wide aspect of significance – from fundamental, scientific to specifically applicative. It can be said that these researches include everything from synthesis, processing, characterization to their application. This book contains 44 papers published in SCI journals since 1999 until May 2007. It is divided into five sections and each assembles the most important results in the specific area: I Synthesis and Processing, II Synthesis, Properties and Characterization of Biomaterials, III Mechanical Properties and Modelling of Biomaterials, IV Biological Evaluation of Biomaterials, V Behaviour of Biomaterials under Radiation Field.
Download or read book Calcium Orthophosphate Based Bioceramics and Biocomposites written by Sergey V. Dorozhkin and published by John Wiley & Sons. This book was released on 2016-03-17 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the advances made in recent years, this is a comprehensive overview of calcium orthophosphates for bioceramics and biocomposites with a special focus on the detailed description of all those available, including their biological and geological occurrence, preparation, chemical composition, structure-property relationships and applications. In particular, the book discusses the suitability of these orthophosphates for biomedical applications and their use as bone grafts in surgery and medicine. The result is a useful reference for researchers with an academic, medical or commercial background.
Download or read book Biocomposites and Hybrid Biomaterials of Calcium Orthophosphates with Polymers written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2018-09-29 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title gives an overview of composites and biocomposites. It discusses the history of CaPO4/ /polymer biocomposites and hybrid biomaterials, as well as analyzing the latest developments in the field. It also covers bioactivity and biodegradation of CaPO4-based biomaterials.
Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha
Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophosphates. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. A comprehensive overview of calcium orthophosphates, this book highlights their importance and biomedical uses.
Download or read book Designing Bioactive Polymeric Materials For Restorative Dentistry written by Mary Anne Sampaio de Melo and published by CRC Press. This book was released on 2020-11-26 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restorative biomaterials in dentistry are designed to restore the shape and function of teeth. Their applicability is related to restorative procedures such as dental restorations, dentures, dental implants, and endodontic materials. Designing Bioactive Polymeric Materials for Restorative Dentistry reviews the current state of the art for restorative biomaterials and discusses the near-future trends in this field. The book examines the biomaterials utilized in restorative dental applications (bonding, composites, cements, and ceramics) and assesses the design for these materials and the role of nanotechnology. All of the contributors are active clinical dentists and researchers in this field. FEATURES Overviews the major ongoing research efforts on developing bioactive bonding systems and composites in dental biomaterials Focuses on emerging trends in restorative dental biomaterials Incorporates evidence-based data on new restorative dental materials throughout the book Features extensive references at the end of each chapter to enhance further study Mary Anne S. Melo, DDS, MSc, PhD FADM, is an Associate Professor and Division Director of Operative Dentistry at the School of Dentistry, University of Maryland, Baltimore, Maryland.
Download or read book Calcium Orthophosphate Based Bioceramics and Biocomposites written by Sergey V. Dorozhkin and published by John Wiley & Sons. This book was released on 2016-03-23 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the advances made in recent years, this is a comprehensive overview of calcium orthophosphates for bioceramics and biocomposites with a special focus on the detailed description of all those available, including their biological and geological occurrence, preparation, chemical composition, structure-property relationships and applications. In particular, the book discusses the suitability of these orthophosphates for biomedical applications and their use as bone grafts in surgery and medicine. The result is a useful reference for researchers with an academic, medical or commercial background.
Download or read book Fiber and Ceramic Filler Based Polymer Composites for Biomedical Engineering written by Jyotishkumar Parameswaranpillai and published by Springer Nature. This book was released on with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomaterials for Tissue Engineering written by Mehdi Razavi and published by Bentham Science Publishers. This book was released on 2017-10-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the published knowledge about bioactive composites, protein scaffolds and hydrogels. Chapters also detail the production parameters and clarify the evaluation protocol for analysis or testing and scaffolding biomaterials. The volume concludes with a summary of applications of porous scaffold in medicine. Each chapter links basic scientific and engineering concepts to practical applications for the benefit of the reader. The text offers a wealth of information that will be of use to all students, bioengineers, materials scientists, chemists, physicians and surgeons concerned with the properties, performance, and the application of tissue engineering scaffolds in clinical settings.
Download or read book Octacalcium Phosphate Biomaterials written by Gerard Insley and published by Woodhead Publishing. This book was released on 2019-11-20 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterials Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration
