Download or read book Amorphous Calcium Phosphate as Bioactive Filler in Polymeric Dental Composites written by Drago Skrtic and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: As biocompatible and osteo-inductive precursor to biological apatite formation, amorphous calcium phosphate (ACP) resorbs at the rate that closely coincides with the rate of new bone formation and is more osteo-conductive than its crystalline counterpart. In addition, in the oral environment, ACP intrinsically provides a protracted supply of the remineralizing calcium and phosphate ions needed for regeneration of mineral lost to tooth decay. These features make ACP composites a strong remineralizing tool at the site of caries attack. Our group has been on the forefront of the research on bioactive, remineralizing, polymeric ACP-based dental materials for over two decades. This entry describes methods for filler, polymer, and composite fabrication and a battery of physicochemical and biological tests involved in evaluation of ACP-based restoratives. Also presented is our most recent design of ACP remineralizing composites with added antimicrobial capability that shows promise for extended dental and, potentially, wider biomedical applications.

Download or read book Amorphous Calcium Phosphate Based Bioactive Polymeric Composites written by and published by DIANE Publishing. This book was released on with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Designing Bioactive Polymeric Materials For Restorative Dentistry written by Mary Anne Sampaio de Melo and published by CRC Press. This book was released on 2020-11-27 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Restorative biomaterials in dentistry are designed to restore the shape and function of teeth. Their applicability is related to restorative procedures such as dental restorations, dentures, dental implants, and endodontic materials. Designing Bioactive Polymeric Materials for Restorative Dentistry reviews the current state of the art for restorative biomaterials and discusses the near-future trends in this field. The book examines the biomaterials utilized in restorative dental applications (bonding, composites, cements, and ceramics) and assesses the design for these materials and the role of nanotechnology. All of the contributors are active clinical dentists and researchers in this field. FEATURES Overviews the major ongoing research efforts on developing bioactive bonding systems and composites in dental biomaterials Focuses on emerging trends in restorative dental biomaterials Incorporates evidence-based data on new restorative dental materials throughout the book Features extensive references at the end of each chapter to enhance further study Mary Anne S. Melo, DDS, MSc, PhD FADM, is an Associate Professor and Division Director of Operative Dentistry at the School of Dentistry, University of Maryland, Baltimore, Maryland.

Download or read book Structural and Dynamical Studies of Acid mediated Conversion in Amorphous calcium phosphate Based Dental Composites written by and published by . This book was released on 2014 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our objective was to investigate the complex structural and dynamical conversion process of the amorphous-calcium-phosphate (ACP)-to-apatite transition in ACP based dental composite materials. Composite disks were prepared using zirconia hybridized ACP fillers (0.4 mass fraction) and photo-activated Bis-GMA/TEGDMA resin (0.6 mass fraction). We performed an investigation of the solution-mediated ACP-to-apatite conversion mechanism in controlled acidic aqueous environment with in situ ultra-small angle X-ray scattering based coherent X-ray photon correlation spectroscopy and ex situ X-ray diffraction, as well as other complementary techniques. We established that the ACP-to-apatite conversion in ACP composites is a two-step process, owing to the sensitivity to local structural changes provided by coherent X-rays. Initially, ACP undergoes a local microstructural rearrangement without losing its amorphous character. We established the catalytic role of the acid and found the time scale of this rearrangement strongly depends on the pH of the solution, which agrees with previous findings about ACP without the polymer matrix being present. In the second step, ACP is converted to an apatitic form with the crystallinity of the formed crystallites being poor. Separately, we also confirmed that in the regular Zr-modified ACP the rate of ACP conversion to hydroxyapatite is slowed significantly compared to unmodified ACP, which is beneficial for targeted slow release of functional calcium and phosphate ions from dental composite materials. Significantly, for the first time, we were able to follow the complete solution-mediated transition process from ACP to apatite in this class of dental composites in a controlled aqueous environment. A two-step process, suggested previously, was conclusively identified.

Download or read book The Effect of Filler on the Mechanical Properties of a Novel Resin based Calcium Phosphate Cement written by Laila Al Dehailan and published by . This book was released on 2010 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several studies have found that resin-based amorphous calcium phosphate (ACP) composites can function well for applications that do not require high mechanical demand. Milled tricalcium phosphate (TCP), a new calcium-phosphate-releasing material, is crystalline in nature, suggesting it to be strong. In the present study, we investigated the use of a TCP-filled composite resin as a possible tooth restorative-material. An experimental TCP-based composite was prepared using monomer with a mixture of 34.3 percent by mass of EBPADMA, 34.2 percent by mass of HmDMA, and 30.5 percent by mass of HEMA. TCP fillers were added to the monomer mixture at different levels (30 percent, 40 percent, 50 percent, and 60 percent by weight). A universal testing machine (Sintech Renew 1121; Instron Engineering Corp., Canton, MA) was used to measure the compressive strength and modulus. FTIR was used to measure the degree of conversion. The depth of cure was determined according to the ISO standards for dental resin 4049 using the scrapping technique. Knoop hardness numbers were obtained by a microhardness tester (M-400; Leco Co., St. Joseph, MI). The viscosities of the experimental resin were determined in a viscometer (DV-II+ Viscometer; Brookfield, Middleboro, MA). The data were analyzed using a one-way analysis of variance (ANOVA). A 5-percent significance level was used for all the tests. Resin composites with 30-percent TCP filler showed the highest compressive strength and hardness values. Also, this group showed the lowest degree of conversion. Resin composites with 60-percent TCP filler showed the highest degree of conversion. However, this group showed the lowest compressive strength, depth of cure, and hardness. Resin composites with 50-percent filler showed the highest compressive modulus. Resin composites with 40-percent filler showed higher viscosity values than resin composites with 30-percent filler. In conclusion, increasing the filler level significantly reduced the compressive strength, hardness, and depth of cure, but increased the degree of conversion. Also, resin composites with the lowest filler level (30 percent) had the highest compressive strength, depth of cure, and hardness. From these results, it can be concluded that the experimental TCP-filled resin used in this study cannot be used as restorative material.

Download or read book Amorphous Calcium Phosphate Composites of a Phenylalanine based Poly ester Urea Poly 1 phe 6 written by Gabrielle Victoria Seifert and published by . This book was released on 2016 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical size bone defects are large defects that do not spontaneously heal over time and result in permanent non-union of the bone. These abnormalities can result from traumas, surgeries, and diseases. Surgical methods used to treat these defects include natural (autografts and allografts) and synthetic bone grafts. Autografts draw advantages from diminished immune response but suffer from complications during implantation as well as pain and cosmetic defects during removal. Allograft complications include rejection and infection. Infection can be minimized by sterile processing techniques, but this frequently leads to diminished mechanical properties post-processing. As a consequence of these limitations, synthetic bone grafts have drawn significant interest. Synthetic bone grafts include biodegradable polymers, metals, and ceramics. For example, poly(caprolactone) (PCL) and poly(L-lactic acid) (PLLA) are biodegradable polymers used widely for medical applications. These materials can be molded into any desired shape; however, they are unsuitable for load-bearing applications as a consequence of their poor mechanical properties post-processing. Bioceramics, such as amorphous calcium phosphate (ACP), benefit from their osteoconductive behavior but are too brittle for load-bearing applications. Combining the biodegradable polymers with bioceramics have shown increased mechanical properties in the composites. The goal of this study was to examine the resulting mechanical properties of combining an L-phenylalanine-based poly(ester urea) (PEU) with various amount of ACP. We hypothesize that adding ACP to the polymer will lead to enhanced mechanical properties compared to the pure polymer.

Download or read book Contemporary Topics about Phosphorus in Biology and Materials written by David Churchill and published by BoD – Books on Demand. This book was released on 2020-09-09 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a diverse set of topics regarding phosphorus chemistry, namely phosphates and closely related chemical systems. Divided into two sections, chapters cover such topics as phosphate dynamics and phosphates in biomaterials. This volume is a useful reference for scholars and researchers and will inspire readers to make future discoveries in the field.

Download or read book Polymeric Drugs and Drug Delivery Systems written by Raphael M. Ottenbrite and published by CRC Press. This book was released on 2019-04-30 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Download or read book Calcium Phosphates in Biological and Industrial Systems written by Zahid Amjad and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Phosphates in Biological and Industrial Systems provides a comprehensive discussion on calcium phosphates in the diverse areas of their applications. The authors are all respected specialists in their particular fields, possessing wide knowledge and experience and able to analyze recent results and relate them to their respective areas of expertise. New information, as well as a review of current concepts, highlights the individual contributions. Due to the broad scope of the subject covered and the large number of contributions, this book is divided into three parts. Whilst each section contains a basic theme, there is a considerable overlapping of ideas and approaches. This reflects the excitement and interdisciplinary nature of investigations by researchers interested in dissimilar aspects of calcium phosphates. Considering the general interest in calcium phosphates, Calcium Phosphates in Biological and Industrial Systems is directed at an audience of researchers in the fields of biology, chemistry, dentistry, geology, chemical engineering, environmental engineering, and medicine. It will also be useful to technology-focused researchers in industry whose investigations might be related directly or indirectly to calcium phosphates.

Download or read book Bacterial Interactions with Dental and Medical Materials written by Mary Anne Melo and published by MDPI. This book was released on 2021-02-05 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interaction of bacteria with biomaterials’ surfaces has critical clinical implications on the development and progression of biofilm-related diseases. In this book "Bacterial Interactions with Dental and Medical Materials", encouraging findings on tissue-contacting biomaterials to control biofilms, enhanced understanding of key mechanisms, and clinical perspectives are discussed toward improving healthcare.

Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophosphates. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. A comprehensive overview of calcium orthophosphates, this book highlights their importance and biomedical uses.

Download or read book Processing and Properties of Bioactive Bioresorbable Polymer calcium Phosphate Composites for Orthopaedic Applications written by Samuel Isaac Jojo Wilberforce and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Publications of the National Institute of Standards and Technology Catalog written by National Institute of Standards and Technology (U.S.) and published by . This book was released on 1994 with total page 1162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Dental Biomaterials An Issue of Dental Clinics of North America E Book written by Jack Ferracane and published by Elsevier Health Sciences. This book was released on 2022-10-12 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Dental Clinics, guest editors Drs. Jack L. Ferracane, Luiz E. Bertassoni, and Carmem S. Pfeifer bring their considerable expertise to the topic of Dental Biomaterials. Dental biomaterials have received recent attention in terms of exhibiting excellent performance, as well as increased migration and proliferation of cells involved in the osseointegration of implants. This issue offers up-to-date, expert coverage of adhesives, cements, composites, ceramics, scaffold materials, and implants, as well as light curing and safety of dental materials. Contains 11 practice-oriented topics including dental adhesives: surface modifications of tooth structure for stable bonding; resin-based composites: materials for direct and indirect applications; new technologies for restorative dentistry; advances in ceramics for dental applications; cements and protocols for bonded dental ceramics; and more. Provides in-depth clinical reviews on dental biomaterials, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Polymers for Dental and Orthopedic Applications written by Shalaby W. Shalaby and published by CRC Press. This book was released on 2006-11-20 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances not only in the creation of new polymers but also in their processing and production have ushered in huge strides in a variety of biomedical and clinical areas. Orthopedics and dentistry are two such areas that benefit immensely from developments in polymer science and technology. Polymers for Dental and Orthopedic Applications

Download or read book Handbook of Bioceramics and Biocomposites written by Iulian Vasile Antoniac and published by Springer. This book was released on 2016-05-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes several current trends in the development of bioceramics and biocomposites for clinical use in the repair, remodelling, and regeneration of bone tissue. Comprehensive coverage of these materials allows fundamental aspects of the science and engineering to be seen in close relation to the clinical performance of dental and orthopaedic implants. Bioceramics and biocomposites appear to be the most dynamic area of materials development for both tissue engineering and implantable medical devices. Almost all medical specialties will continue to benefit from these developments, but especially dentistry and orthopaedics. In this Handbook, leading researchers describe the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Also described are technologies for bioceramics and biocomposites processing in order to fabricate medical devices for clinical use. Another important section of the book is dedicated to tissue regeneration with development of new matrices. A targeted or personalized treatment device reduces drug consumption and treatment expenses, resulting in benefits to the patient and cost reductions for public health systems. This authoritative reference on the state-of-the-art in the development and use of bioceramics and biocomposites can also serve as the basis of instructional course lectures for audiences ranging from advanced undergraduate students to post-graduates in materials science and engineering and biomedical engineering.

Download or read book Integrated Biomaterials for Biomedical Technology written by Murugan Ramalingam and published by John Wiley & Sons. This book was released on 2012-07-31 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting edge book provides all the important aspects dealing with the basic science involved in materials in biomedical technology, especially structure and properties, techniques and technological innovations in material processing and characterizations, as well as the applications. The volume consists of 12 chapters written by acknowledged experts of the biomaterials field and covers a wide range of topics and applications including: The different types of nanobiomaterials How to generate porous biomaterials for tissue engineering Calcium phosphate-based biomaterials intended for mineralized tissue regenerative applications Nanocrystalline form of calcium phosphates Design and fabrication of SiO2 nanoparticles New kinds of titanium alloy implants Injectable growth factor system based on bone morphogenetic proteins Impedance sensing of biological processes in mammalian cells Hydrogels-based implantable glucose sensors Molecular design of multifunctional polymers for gene transfection Hydrogels and their potential biomedical applications Hybrid biomaterials with high mechanical and biological properties