Download or read book Corynebacterium glutamicum written by Nami Tatsumi and published by Springer Science & Business Media. This book was released on 2012-08-14 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its “microbial factory” qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins. This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
Download or read book Microbial Production of L Amino Acids written by Robert Faurie and published by Springer. This book was released on 2003-07-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume deals with "Microbial Production of L-Amino Acids" and presents five comprehensive, expert and actual review articles on the modern production of Amino Acids by application of biotechnologically optimized microorganisms. This includes not only the modern techniques of enzyme, metabolic and transport engineering but also sophisticated analytical methods like metabolic flux analysis and subsequent pathway modeling. A general review about industrial processes of Amino Acid production provides a comprehensive overview about recent strain development as well as fermentation technologies. It was our special interest to focus the other articles on the most important and best selling amino acids on the world market i.e. L-Glutamate, L-Lysine and L-Threonine. The authors of this special volume have contributed significantly to the progress of Amino Acid biotechnology in the last decades and earn our special gratitude and admiration for their expert review articles.
Download or read book Amino Acid Fermentation written by Atsushi Yokota and published by Springer. This book was released on 2017-05-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings on amino acid fermentation and reviews the 50-year history of their development. The book is divided into four parts, the first of which presents a review of amino acid fermentation, past and present. The second part highlights selected examples of amino acid fermentation in more detail, while the third focuses on recent advanced technologies. The last part introduces readers to several topics for future research directions in amino acid production systems. A new field, “amino acid fermentation”, was created by the progress of academic research and industrial development. In 1908, the Japanese researcher Kikunae Ikeda discovered glutamate as an Umami substance. Then a new seasoning, MSG (monosodium glutamate), was commercialized. Although glutamate was extracted from the hydro-lysate of wheat or soybean in the early days, a new production method was subsequently invented – “fermentation” – in which glutamate is produced from sugars such as glucose by a certain bacterium called Corynebacterium. The topic of this volume is particularly connected in a significant way with biochemical, biotechnological, and microbial fields. Both professionals in industry and an academic audience will understand the importance of this volume.
Download or read book Recent Progress in Microbial Production of Amino Acids written by Hitoshi Enei and published by CRC Press. This book was released on 1989 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: With emphasis on recent advances, this book describes the microbial method of amino acid production: the breeding of amino acid-producing microorganisms, the direct fermentation method, the precursor addition method, the enzymatic method, and biochemical engineering aspects. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Biotechnology of Amino Acid Production written by Kō Aida and published by Elsevier Science & Technology. This book was released on 1986 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past few decades, microbiologists and biochemists have introduced molecular biology and genetic engineering to the field of applied and industrial microbiology. Amino acid fermentation is the practical result of biotechnology which integrates microbiology, biochemistry and chemical engineering. This volume discusses the general aspects of amino acid fermentation fundamental to industrial use. The microorganisms and their biosynthetic pathways and related enzymes are described in detail in order to clarify the regulatory mechanism of the microbial metabolism. In particular, the various amino acids are treated separately in individual chapters, including descriptions of the development of biochemical processes. The book covers general and specific aspects of microbiology research, past, present and future.
Download or read book Systems Metabolic Engineering written by Christoph Wittmann and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Download or read book Food Components to Enhance Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1994-02-01 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.
Download or read book Production of Platform Chemicals from Sustainable Resources written by Zhen Fang and published by Springer. This book was released on 2017-06-14 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides state-of-the-art reviews, the latest research, prospects and challenges of the production of platform chemicals such as C6 sugars, 5-hydroxymethylfurfural, furfural, gamma-valerolactone, xylitol, 2,5-furandicarboxylic acid, levulinic acid, ethanol and others from sustainable biomass resources using processes that include heterogeneous catalysis, ionic liquids, hydrothermal/solvothermal, electrochemical and fermentation methods. It also discusses the application of these chemicals and their derivatives for synthesizing commodity chemicals via various routes. Intended as a reference resource for researchers, academicians and industrialists in the area of energy, chemical engineering and biomass conversion, it provides a wealth of information essential for assessing the production and application of various biomass-derived platform chemicals using biological, chemical and electrochemical techniques.
Download or read book New Trends in Corynebacterium Glutamicum written by Carlos Barreiro and published by . This book was released on 2015 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than fifty years of scientific and industrial developments focused on the amino acid producer bacterium Corynebacterium glutamicum has successfully yielded up to 2.93 and 1.95 million tons/year of L glutamic acid and L-lysine, respectively. As a result of this biotechnological effort, a massive amount of knowledge decidedly applicable to the development of new products has been gained. Nowadays, this knowledge is used to enlarge the portfolio of C. glutamicum industrial products, since they are highly relevant as chemicals, biodegradable polymers, ingredients, or additives in food, feed, cosmetics and pharmaceuticals. This book addresses production of these new metabolites (C. glutamicum applications) and their potential under the expert point of view of those groups directly involved in their developments. Thus, amino acids out of the traditional glutamic acid or lysine, as L valine; food colorants such as carotenoids; dicarboxylic acids used as building blocks (e.g: succinate); alpha hydroxy acids as L lactate, D lactate or glycolate; biodegradable polyester (eg.: polyhydroxybutyrate); alcohols for biofuel as isobutanol as well as bioremediation applications of the new developments around C. glutamicum described in this book. Those industrial relevant compounds come to the market parallel with the developing application of new technologies. Hence, cell activity as a whole by means of the Proteomics or Transcriptomics approaches, as well as the methodologies that mimic the large fermetor conditions in a scale-down format are also reviewed in the book. Additionally, a historical description and an updated review of the taxonomical environment of Corynebacterium genus open an essential manual for enterprises, researchers and academia involved in Actinobacteria, secondary metabolite production and industrial applications. This book reviews the evolution of almost sixty years of development, initially focused on amino acid production, which unleashes the idea of C. glutamicum as a biorefinery due to its ability to generate hundreds of products demanded by the market.
Download or read book Nutritional Improvement of Food and Feed Proteins written by Mendel Friedman and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 879 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nutritional quality of a protein depends on the proportion of its amino acids-especially the essential amino acids-their physio logical availability, and the specific requirements of the consumer. Availability varies and depends on protein source, interaction with other dietary components, and the consumer's age and physiological state. In many foods, especially those from plants, low levels of various essential amino acids limits their nutritive value. This is particularly important for cereals (which may be inadequate in the essential amino acids isoleucine, lysine, threonine, and tryto phan) and legumes (which are often poor sources of methionine). Moreover, these commodities are principle sources of protein for much of the earth's rapidly growing population. At the current annual growth rate of about 2 percent, the world population of about 4 billion will increase to 6.5 billion by the year 2000 and to 17 billion by the year 2050. Five hundred milliQn people are presently estimated to suffer protein malnutrition, with about fifteen thousand daily deaths. The ratio of malnourished to adequately nourished will almost surely increase. For these reasons, and especially in view of the limited availability of high quality (largely animal) protein to feed present and future populations, improvement of food and feed quality is especially important.
Download or read book Amino Acids Intermediates Global Report written by Editorial Nin and published by Createspace Independent Publishing Platform. This book was released on 2018-09-04 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: AMINO ACIDS & INTERMEDIATES GLOBAL REPORT The Amino Acids & Intermediates Report gives Market Consumption Data for 31 Products & Services in 100 countries, by each (Lighting equipment, miscellaneous) 6 to 10-Digit NAICS Product Code, by Time series: Historic for the past 7 years, and Forecasts for the next 7 years. The Amino Acids & Intermediates Report covers about 100 significant countries individually; in addition this report also contains a World Total, and 9 Regional Totals. MARKET DATA in US$ by Country by each of 86 Products / Services by Year: Historic for the past 7 years, and Forecasts for the next 7 years. FINANCIAL DATA for each Country for each Financial and Balance Sheet item by each year: Historic for the past 7 years, and Forecasts for the next 7 years. INDUSTRY DATA for each Country for each Industry item by period (Previous / Current / Forecast). AMINO ACIDS & INTERMEDIATES 1. Amino Acids & Intermediates 2. Alanine CAS 56-41-7 3. Arginine CAS 74-79-3 4. Asparagine CAS 70-47-3 5. Aspartic acid CAS 56-84-8 6. Cysteine CAS 52-90-4 7. Glutamic acid CAS 56-86-0 8. Glutamine CAS 56-85-9 9. Glycine CAS 56-40-6 10. Histidine CAS 71-00-1 11. Isoleucine CAS 73-32-5 12. Leucine CAS 61-90-5 13. Lysine CAS 56-87-1 14. Methionine CAS 63-68-3 15. Phenylalanine CAS 63-91-2 16. Proline CAS 147-85-3 17. Pyrrolysine CAS 448235-52-7 18. Selenocysteine CAS 10236-58-5 19. Serine CAS 56-45-1 20. Threonine CAS 72-19-5 21. Tryptophan CAS 73-22-3 22. Tyrosine CAS 60-18-4 23. Valine CAS 72-18-4 24. Ketogenic amino acid (Miscellaneous + Degraded Acetyl-CoA) 25. Glucogenic amino acid (Miscellaneous + Gluconeogenic precursors) 26. Non-proteinogenic amino acid (Miscellaneous + precursors) 27. Arginine: Agmatine 28. Arginine: Cadaverine 29. Arginine: Citrulline 30. Arginine: Ornithine 31. Arginine: Putrescine 32. Cysteine / Glutamate / Glutathione: y-Glutamylcysteine 33. Glycibe / Serine: 3-Phosphoglyceric acid 34. Glycibe / Serine: Creatinine 35. Glycibe / Serine: Phosphocreatine 36. Glycine / Creatine: Glycocyamine 37. Histidine: Formiminoglutamic acid 38. Histidine: Glutamate-1-semialdehyde 39. Histidine: Imidazol-4-one-5-propionic acid 40. Histidine: Urocanic acid 41. Isoleucine: 2,3-Dihydroxy-3-methylpentanoic acid 42. Isoleucine: 2-Methylacetoacetyl-CoA 43. Isoleucine: 2-Methylbutyryl-CoA 44. Isoleucine: Tiglyl-CoA 45. Leucine: 3-Methylcrotonyl-CoA 46. Leucine: 3-Methylglutaconyl-CoA 47. Leucine: HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A 48. Leucine: Isovaleryl-CoA 49. Leucine: a-Ketoisocaproic acid 50. Leucine: ß-hydroxy ß-methylbutyric acid 51. Leucine: ß-hydroxy ß-methylbutyryl-CoA 52. Lysine: Allysine 53. Lysine: Crotonyl-CoA 54. Lysine: Glutaconyl-CoA 55. Lysine: Glutaryl-CoA 56. Lysine: Saccharopine 57. Lysine: a-Aminoadipic acid 58. Lysine: a-Ketoadipate 59. Lysine: ß-Hydroxybutyryl-CoA 60. Methionine: alpha-Ketobutyric acid + Cysteine 61. Methionine: Cysteine: Cystathionine 62. Methionine: Homocysteine 63. Methionine: S-Adenosyl methionine 64. Methionine: S-Adenosyl-L-homocysteine 65. Ornithine: urea products 66. Phenylalanine / Tyrosine: 4-Hydroxyphenylpyruvic acid 67. Phenylalanine / Tyrosine: 4-Maleylacetoacetic acid 68. Phenylalanine / Tyrosine: Homogentisic acid 69. Proline: 1-Pyrroline-5-carboxylic acid 70. Propionyl: Methylmalonyl-CoA 71. Threonine: a-Ketobutyric acid 72. Tryptophan / Alanine: 2-Amino-3-carboxymuconic semialdehyde 73. Tryptophan/ Alanine: 2-Aminomuconic acid 74. Tryptophan / Alanine: 2-Aminomuconic semialdehyde 75. Tryptophan / Alanine: 3-Hydroxyanthranilic acid 76. Tryptophan / Alanine: 3-Hydroxykynurenine 77. Tryptophan / Alanine: Anthranilic acid 78. Tryptophan / Alanine: Glutaryl-CoA 79. Tryptophan / Alanine: Kynurenine 80. Tryptophan / Alanine: N'-Formylkynurenine 81. Valine: 2-Methyl-3-oxopropanoic acid 82. Valine: 3-Hydroxyisobutyric acid 83. Valine: 3-Hydroxyisobutyryl-CoA 84. Valine: Isobutyryl-CoA 85. Valine: Methacrylyl-CoA 86. Valine: a-Ketoisovaleric acid
Download or read book Natural Products in the Chemical Industry written by Bernd Schaefer and published by Springer. This book was released on 2015-05-26 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products. This book features diverse compound classes from a number of areas: colourants, fragrances and flavourings, amino acids, pharmaceuticals, hormones, vitamins and agrochemicals. Whether you are a teacher or a scholar, an undergraduate or graduate student, a professional chemist in industry or academia, or someone just interested in natural sciences, this book allows you to be inspired and entertained by facts and information along with enjoyable anecdotes, historical, economic, political, biological and social considerations. Experts in the field can have a pleasurable time cruising through captivating synthesis methods, which enable the generation of complex molecules on industrial scale. This book · deals with the manufacturing of larger quantities of complex molecules (asymmetric and heterocyclic compounds, polycyclic structures, macrocycles and small rings) · displays all reaction schemes in colour, which makes them easy to read · highlights aesthetics and elegance in modern industrial organic chemistry
Download or read book Biotechnological Innovations in Food Processing written by BIOTOL and published by Butterworth-Heinemann. This book was released on 2014-06-28 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough examination of the ways in which recent biotechnological developments have led to improvements in food processing. Deals with biotechnology based processes currently in use by or available to the food industry. Building on a series of case studies selected to illustrate the diversity of applications it clearly shows that biotechnology can and will benefit the food industry. The need for a cost-effective training scheme for new and existing staff at all levels has been met by the University of Greenwich (formerly Thames Polytechnic) and the Open University of the Netherlands. As part of the European Community Education and Technology Training initiative (COMETT) and in conjunction with a number of other leading UK and European universities, they have developed BIOTOL, a training scheme in biotechnology using open learning materials, which will provide tailor-made courses, flexible in content, pace and place.
Download or read book Amino Acid Homopolymers Occurring in Nature written by Yoshimitsu Hamano and published by Springer Science & Business Media. This book was released on 2010-07-30 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms are capable of producing a wide variety of biopolymers. Homopolymer peptides, which are made up of only a single type of amino acid, are far less ubiquitous. The only two amino-acid homopolymers known to occur in nature are presented in this volume. Poly-epsilon-L-lysine is a polycationic peptide and exhibits antimicrobial activity against a wide spectrum of microorganisms. It is both safe and biodegradable and is therefore used as a food preservative in several countries. In addition, there has been great interest in medical and other applications of poly-lysine and its derivatives. In contrast, poly-gamma-glutamic acid is an unusual anionic polypeptide. It is also water soluble, biodegradable, edible, non-toxic and non-immunogenic and can be chemically modified to introduce various drugs. These features are very useful for pharmaceutical and biomedical applications. Poly-glutamic acid is also a highly attractive as a food ingredient.
Download or read book Novel Proteins for Food Pharmaceuticals and Agriculture written by Maria Hayes and published by John Wiley & Sons. This book was released on 2018-11-28 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: A groundbreaking text that highlights the various sources, applications and advancements concerning proteins from novel and traditional sources Novel Proteins for Food, Pharmaceuticals and Agriculture offers a guide to the various sources, applications, and advancements that exist and are currently being researched concerning proteins from novel and traditional sources. The contributors—noted experts in the field—discuss sustainable protein resources and include illustrative examples of bioactive compounds isolated from several resources that have or could obtain high market value in specific markets. The text also explores a wide range of topics such as functional food formulations and pharmaceutical applications, and how they alter biological activity to provide therapeutic benefits, nutritional values and health protection. The authors also examine the techno-functional applications of proteins and looks at the screening process for identification of bioactive molecules derived from protein sources. In addition, the text provides insight into the market opportunities that exist for novel proteins such as insect, by-product derived, macroalgal and others. The authors also discuss the identification and commercialization of new proteins for various markets. This vital text: Puts the focus on the various sources, applications and advancements concerning proteins from novel and traditional sources Contains a discussion on how processing technologies currently applied to dairy could be applied to novel protein sources such as insect and macroalgal Reviews the sustainability of protein sources and restrictions that exist concerning development Offers ideas for creating an innovative and enterprising economy that is built on recent developments Details the potential to exploit key market opportunities in sports, infant and elderly nutrition and techno-functional protein applications Written for industrial researchers as well as PhD and Post-doctoral researchers, and undergraduate students studying biochemistry, food engineering and biological sciences and those interested in market developments, Novel Proteins for Food, Pharmaceuticals and Agriculture offers an essential guide to the sources, applications and most recent developments of the proteins from both innovative and traditional sources.
Download or read book Amino Acids in Nutrition and Health written by Guoyao Wu and published by Springer Nature. This book was released on 2021-03-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids (AAs) are not only building blocks of protein, but are also signalling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health and well-being of individuals. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Download or read book Recent Progress in Microbial Production of Amino Acids written by Hitoshi Enei and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
