Download or read book Altered Genes Omnibus Books 1 2 3 written by Mark K. Kelly and published by Mark K. Kelly. This book was released on 2018-11-23 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: To save the world, first they have to save themselves… When an unconscious British businessman arrives at New York City’s Bellevue Hospital, Dr. Mei Ling unwittingly finds herself in the midst of an infectious outbreak. Meanwhile, Professor Tony Simmons, her ex-lover, and a world-renowned geneticist at Georgetown University receives an enigmatic telephone call that hints at a genetic threat, unlike anything the world has ever seen. As the pandemic spreads, governments close their borders and quarantine cities. Simmons is taken to a secret military laboratory to search for a cure. But it’s the truth he finds instead, and now he, Ling, and an odd group of survivors are on the run as civilization collapses around them. A superb action-packed thriller based on frighteningly realistic science. Perfect for fans of Michael Crichton, Robin Cook or William R. Forstchen. Get a copy today and immerse yourself in an apocalyptic future you’ll hope won’t ever happen. The Altered Genes Trilogy consists of: Altered Genes : Genesis Altered Genes : Revelations Altered Genes : Resurrection

Download or read book Genome wide view on the physiology of vitamin D written by Carsten Carlberg and published by Frontiers E-books. This book was released on 2014-12-05 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.

Download or read book The Book of the New Sun written by Gene Wolfe and published by Gollancz. This book was released on 2015-03-12 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extraordinary epic, set a million years in the future, in the time of a dying sun, when our present culture is no longer even a memory. Severian, a torturer's apprentice, is exiled from his guild after falling in love with one of his prisoners. Ordered to the distant city of Thrax, armed with his ancient executioner's sword, Terminus Est, Severian must make his way across the perilous, ruined landscape of this far-future Urth. But is his finding of the mystical gem, the Claw of the Conciliator, merely an accident, or does Fate have a grander plans for Severian the torturer . . . ? This edition contains the first two volumes of this four volume novel, The Shadow of the Torturer and The Claw of the Conciliator.

Download or read book The Silver Age of Comic Book Art written by Arlen Schumer and published by Archway Publishing. This book was released on 2014-09-09 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carmine Infantino. Steve Ditko. Jack Kirby. Gil Kane. Joe Kubert. Gene Colan. Jim Steranko. Neal Adams. Some of the greatest comic book artists of their generation, who created some of their greatest work during The Silver Age of Comics (circa1956-1970). They not only drew definitive versions of the medium’s greatest characters including The Flash, Batman, Captain America, Superman, Thor, Green Lantern, Spider-Man, Dr. Strange, Green Arrow and more— but set trends in the art of comic book storytelling. Now this popular and influential body of work, along with each artist’s thoughts, ideas and commentary, is presented in The Silver Age of Comic Book Art, a coffee table comic book art history book written and designed in a daringly different format by comic book historian and illustrator Arlen Schumer, and published in hardcover and digital/e-book editions by Archway Publishing (from Simon & Schuster). Dynamic spreads of the actual printed comic art, graphically enlarged, are integrated with comic-styled text, often by the artists themselves, that replaces the original comic book copy with more personalized prose that places the art firmly in the period it was created: the turbulent 1960s. By creating a comic book history book that reads like a comic book, Schumer succeeds spectacularly in making you see, as if for the first time, the comics you’ve been reading your whole life. “Arlen Schumer documents an important period in comic book history, told with an explosive format and stunning design. It reflects the kinetic rhythm of the era.” — Will Eisner (1917-2005), creator of The Spirit and the graphic novel A Contract with God "Through the years, I’ve had the pleasure of seeing many books that pay tribute to the art of comics, but Arlen Schumer has created an entirely new format in presenting the art and words of the artists. It's the most comprehensive and personal way a fan or colleague can learn what lies beneath the art. Arlen has found the perfect way to inform and entertain. It’s simply awesome —and the best representation of my work ever!” —Gene Colan (1926-2011), legendary comic book artist “A lovingly crafted tribute to the superhero comic of the 1960s, The Silver Age of Comic Book Art recaptures the four-color visionary surge of the era, its jet-age psychedelic rush of imagination and the titanic, luminous figures, both real and imaginary, that glittered in its firmament. For a brief moment in the late 20th century, it seemed as if the spirit of the age wore a vivid leotard, a chest emblem, and traveled in a strobing blur of speed lines. For anyone with any interest in or affection for that moment, this beautiful volume is indispensible.” — Alan Moore, author of Swamp Thing and Watchmen For more on The Silver Age of Comic Book Book Art, join Arlen’s Facebook group of the same name, and visit Arlen’s website: www.arlenschumer.com

Download or read book De Horatio Veterum Latinorum Poetarum Judice Thesis written by Auguste Couat and published by BoD – Books on Demand. This book was released on 2024-03-09 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reprint of the original, first published in 1875.

Download or read book Cancer Bioinformatics written by and published by BoD – Books on Demand. This book was released on 2022-09-28 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the application of bioinformatics in cancer disease management. It covers general aspects of cancer as a disease but also as a success story in the translation of omics data in clinical settings. It provides an overview of the specific applications of bioinformatics tools in cancer epidemiology, prevention, and screening and in the identification of novel genetic and molecular biomarkers involved in cancer development. This is accomplished through the inclusion of numerous examples of the use of bioinformatics in precision oncology.

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Download or read book Clinical Immuno Oncology E Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2023-03-05 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering focused, practical, and up-to-date content on immunotherapies used to treat a wide variety of cancer types, Clinical Immuno-Oncology covers the basic cellular and molecular mechanisms involved in cancer initiation and progression. The text reviews the development of tumor specific antigens and the challenges of developing cancer immunotherapies. Every effort is made to relate the fundamental aspects of host immunity to the efficacy of current immunotherapies and how they work in conjunction with the immune system to combat cancer. This foundational resource explains the basics of cancer immunotherapy, discusses best practices, and provides recommendations from experienced clinicians in the field. Dr. John E. Niederhuber and a team of expert contributing authors provide clinically focused information essential for integrating these new therapies into practice—making this an ideal resource for fellows, practitioners, and other cancer team members in medical oncology, radiation oncology, cancer surgery, immunology, and cancer research. - Offers balanced and synthesized content on clinical science, clinical and translational research, and evidence-based practice for cutting-edge immunotherapies. - Discusses clinical applications of immunotherapies in common types of cancer including melanoma, breast cancer, pancreatic cancer, colon and rectum cancer, prostate cancer, leukemias, and hematologic malignancies. - Includes dedicated chapters on immune responses, innate immunity, active immunization against cancer, and cell-based therapies by leading experts. - Covers key topics such as cancer immunotherapy in the presence of COVID-19, immunotherapeutics, new findings concerning the role of the microbiome in immunotherapy, advances in engineered cell-based therapies, and active immunization against cancer.

Download or read book Computational Medicine written by Zlatko Trajanoski and published by Springer Science & Business Media. This book was released on 2012-09-18 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics.

Download or read book Bell Howell Newspaper Index to the San Francisco Chronicle written by Bell & Howell Co. Indexing Center and published by . This book was released on 1986 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Omnibus Book of British and American Hit Singles 1960 1990 written by Dave McAleer and published by . This book was released on 1990 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurodegenerative Diseases written by Raymond Chuen-Chung Chang and published by BoD – Books on Demand. This book was released on 2011-12-09 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glial cells modulate or promote neurodegeneration. In the next section an evaluation is given of how hormonal and metabolic control modulate disease progression, which is followed by a section exploring some preventive methods using natural products and new pharmacological targets. We also explore how medical devices facilitate patient monitoring. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.

Download or read book A Copious and Critical English Latin Dictionary written by William Smith and published by . This book was released on 1871 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bisphenol A written by Pinar Erkekoglu and published by BoD – Books on Demand. This book was released on 2017-06-07 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bisphenol A (BPA) is a synthetic compound for hardening and clearing polycarbonate plastics. BPA is mainly classified as an estrogen-like endocrine-disrupting chemical. In the last decade, attention has arisen in scientific communities that it is not safe to use this chemical in mainly polycarbonate plastics. Exposure to BPA starts in prenatal period, which is the critical period for its toxic effects on different organs. Throughout this book, the readers will obtain information on the effects of BPA on different systems. They will also get information on the prenatal and postnatal effects of BPA. We believe that readers will get qualified scientific knowledge and a general overview of the toxic effects of BPA exposure and its consequences from this book.

Download or read book Omnibus IV written by Gene Edward Veith (Jr.) and published by Veritas Press. This book was released on 2009-12 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Thesaurus Linguae Latinae Compendiarius written by Ainsworth and published by . This book was released on 1736 with total page 1444 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Copious and Critical English Latin Dictionary written by William Smith and published by BoD – Books on Demand. This book was released on 2023-02-01 with total page 1030 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reprint of the original. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.