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Book Alkaloids  Chemical and Biological Perspectives

Download or read book Alkaloids Chemical and Biological Perspectives written by S.W. Pelletier and published by Elsevier. This book was released on 1999-04-29 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 13 of this series presents five timely reviews of research on alkaloids such as new developments in the chemistry and biology of alkaloids from amphibian skins. It provides a synopsis and tabulation of the hundreds of alkaloids that have been detected, with an emphasis on occurrence, structure, dietary origins, and biological activity. Alkaloids containing the 1, 2, 3, 3a, 8, 8a - hexahydropyrrolo [2,3b] indole ring system and the cyclotryptamines are discussed. An exhaustive list of available structures is provided. The chemical and biological structures have been evaluated critically so as to identify existing errors and expose irregularities in appearance or biological function. In addition, attention is drawn to the possible implications of the accumulated knowledge related to the synthesis, occurrence, and biochemistry of this class of alkaloids.Recent work on alkaloids containing the comparatively non – basic pyrrole ring system is summarized. One of the chapters covers isolation, structure elucidation, biological activity, and selected chemical syntheses of certain pyrrole alkaloids.Recent developments in the chemistry of diterpenoid and norditerpenoid alkaloids occurring in Aconitum, Delphinium and Consolida genera of the Ranunculaceae family used in Chinese and Indian medicine are surveyed and the book ends with a focus on transition metal – catalyzed carbonylations as efficient and novel approaches to the construction of piperidine, izidine and quinazoline alkaloids, which occur in great numbers in nature.

Book Alkaloids  Chemical and Biological Perspectives

Download or read book Alkaloids Chemical and Biological Perspectives written by S. William Pelletier and published by Springer Science & Business Media. This book was released on 2013-03-11 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 7 of Alkaloids: Chemical and Biological Perspectives appears under the aegis of a new publisher: the distinguished firm of Springer Verlag New York, Inc. This volume presents three timely reviews on alkaloids: Chapter 1 reviews the homoerythrina and related alkaloids. a group of compounds occurring in seventeen species that are native to countries bordering the western Pacific. Since the last review in 1981, the number of these alkaloids has doubled. Chapter 2 is a comprehensive review of the carbon-13 NMR spectros copy of steroidal alkaloids. Because more than 350 plant species have yielded steroidal alkaloids and these alkaloids exhibit a wide spectrum of biological activities, including teratogenicity, this catalog of spectral and physical data should prove very useful to workers in this field. Chapter 3 presents a detailed review of proton and carbon-I3 NMR shift assignments and physical constants of norditerpenoid alkaloids. This chap ter is an extensive supplement to the review that appeared in Volume 2 of this series. In addition to the catalog of spectral and physical data, this chapter includes tables of proton and carbon shift assignments, a table of the occurrence of alkaloids in plant species, an index of al1 X-ray crystal structure determinations of norditerpenoid alkaloids, and tables containing molecular formulas versus calculated high-resolution mass values and calculated high-resolution mass values versus molecular formulas of nor diterpenoid alkaloids. Each chapter in this volume has been reviewed by an expert in the field. Indexes for both subjects and organisms are provided.

Book Alkaloids  Chemical and Biological Perspectives

Download or read book Alkaloids Chemical and Biological Perspectives written by S.W. Pelletier and published by Elsevier. This book was released on 2001-12-03 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids: Chemical and Biological Perspectives, the 15th volume of the ACBP series, features four important reviews of research on alkaloids. Chapter 1 is the first comprehensive review of the carbon-13 and proton NMR shift assignments and physical constants of diterpene alkaloids and their derivatives. In addition to the catalogue of spectral and physical data, the chapter includes a table of the occurrences of these alkaloids in various plant species, tables containing molecular formulas versus calculated high-resolution mass values, and calculated high-resolution mass values versus the molecular formulas of diterpenoid alkaloids, as well as seven tables summarizing the carbon-13 chemical shifts of various functional groups in diterpenoid alkaloids. Chapter 2 is a fascinating review of the supercritical fluid extraction of alkaloids. This technique using basic modifiers, provides an alternative method for the extraction of alkaloids. Chapter 3 summarizes recent advances in the synthesis of Amaryllidaceae alkaloids, an important class of naturally-occurring bases and neutral compounds. The increased activity in the synthesis of these alkaloids over the last decade is undoubtedly due to the fact that certain members of this family possess interesting and useful biological properties. Elegant syntheses, chiral and otherwise, of structures incorporating many asymmetric centres are reviewed. Chapter 4 reviews radical cyclization reactions in the total synthesis of indole alkaloids. The use of free radical chemistry in the synthesis of alkaloids has grown markedly because of the mild reaction conditions, tolerance of a wide variety of functional groups, and the good stereoselectivities. Each chapter in this volume has been reviewed by at least one specialist in the field.

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher :
  • Release : 1996
  • ISBN :
  • Pages : 430 pages

Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1996 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the Thalictrum alkaloids. Forty-six new alkaloids are described from fifteen species of the genus Thalictrum, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the Thalictrum alkaloids. Chapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: Taxus). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine. Chapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized. Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related nortropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing. Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher : Wiley
  • Release : 1983-01-20
  • ISBN : 9780471088110
  • Pages : 0 pages

Download or read book Alkaloids written by S. William Pelletier and published by Wiley. This book was released on 1983-01-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Alkaloids

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 2016-01-08
  • ISBN : 9780128034439
  • Pages : 528 pages

Download or read book The Alkaloids written by and published by Academic Press. This book was released on 2016-01-08 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 60 years, The Alkaloids has been the leading book series in the field of alkaloid chemistry. In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered in high-quality timeless reviews written by renowned experts in the field. The Alkaloids is the leading book series in the field of alkaloid chemistry In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher :
  • Release : 2001
  • ISBN :
  • Pages : 0 pages

Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids: Chemical and Biological Perspectives, the 15th volume of the ACBP series, features four important reviews of research on alkaloids. Chapter 1 is the first comprehensive review of the carbon-13 and proton NMR shift assignments and physical constants of diterpene alkaloids and their derivatives. In addition to the catalogue of spectral and physical data, the chapter includes a table of the occurrences of these alkaloids in various plant species, tables containing molecular formulas versus calculated high-resolution mass values, and calculated high-resolution mass values versus the molecular formulas of diterpenoid alkaloids, as well as seven tables summarizing the carbon-13 chemical shifts of various functional groups in diterpenoid alkaloids. Chapter 2 is a fascinating review of the supercritical fluid extraction of alkaloids. This technique using basic modifiers, provides an alternative method for the extraction of alkaloids. Chapter 3 summarizes recent advances in the synthesis of Amaryllidaceae alkaloids, an important class of naturally-occurring bases and neutral compounds. The increased activity in the synthesis of these alkaloids over the last decade is undoubtedly due to the fact that certain members of this family possess interesting and useful biological properties. Elegant syntheses, chiral and otherwise, of structures incorporating many asymmetric centres are reviewed. Chapter 4 reviews radical cyclization reactions in the total synthesis of indole alkaloids. The use of free radical chemistry in the synthesis of alkaloids has grown markedly because of the mild reaction conditions, tolerance of a wide variety of functional groups, and the good stereoselectivities. Each chapter in this volume has been reviewed by at least one specialist in the field.

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher : Wiley-Interscience
  • Release : 1983
  • ISBN :
  • Pages : 472 pages

Download or read book Alkaloids written by S. William Pelletier and published by Wiley-Interscience. This book was released on 1983 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, human inhabitants of Central and South America have poisoned blow darts with alkaloids they extract from the brightly coloured frogs of the rain forests. Volume 4 of

Book The Alkaloids

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 2010-02-19
  • ISBN : 9780123813367
  • Pages : 302 pages

Download or read book The Alkaloids written by and published by Academic Press. This book was released on 2010-02-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective Comprehensive, dynamic reviews written by leading authors in the respective fields Broad coverage on the biological aspects

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher :
  • Release : 1983
  • ISBN :
  • Pages : 424 pages

Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1983 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Chemistry and Biology

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 1997-11-20
  • ISBN : 9780080865744
  • Pages : 590 pages

Download or read book Chemistry and Biology written by and published by Academic Press. This book was released on 1997-11-20 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind. Indispensable reference work written by leading experts in the field Provides up-to-date, timely reviews on compounds and classes of great interest Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation An essential research tool for anyone working with alkaloids from a chemical or biological perspective

Book The Alkaloids

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 2011-11-21
  • ISBN : 0123914884
  • Pages : 177 pages

Download or read book The Alkaloids written by and published by Academic Press. This book was released on 2011-11-21 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than 40 years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective. Comprehensive, dynamic reviews written by leading authors in the respective fields. Broad coverage on the biological aspects.

Book The Alkaloids

    Book Details:
  • Author :
  • Publisher : Academic Press
  • Release : 2003-10-31
  • ISBN : 9780124695603
  • Pages : 414 pages

Download or read book The Alkaloids written by and published by Academic Press. This book was released on 2003-10-31 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective Comprehensive dynamic reviews written by the leading authors in the respective fields Broader coverage than before on the biological aspects

Book Alkaloids

    Book Details:
  • Author :
  • Publisher :
  • Release : 1984
  • ISBN :
  • Pages : 0 pages

Download or read book Alkaloids written by and published by . This book was released on 1984 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Alkaloids

    Book Details:
  • Author :
  • Publisher : Elsevier
  • Release : 2003-10-13
  • ISBN : 0080521495
  • Pages : 415 pages

Download or read book The Alkaloids written by and published by Elsevier. This book was released on 2003-10-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series is world-renowned as the leading compilation of current reviews of this vast field. Internationally acclaimed for more than forty years, The Alkaloids: Chemistry and Biology, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of this rapidly expanding field. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Up-to-date reviews on a large and very important group of natural products from both a chemical and biological perspective Comprehensive dynamic reviews written by the leading authors in the respective fields Broader coverage than before on the biological aspects

Book Alkaloids  Chemical and Biological Perspectives

Download or read book Alkaloids Chemical and Biological Perspectives written by S. William Pelletier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 8 of this series presents four timely reviews on alkaloids: Chapter 1 is a magnificent and monumental review of curare, "a group of dart and/or arrow poisons varying in composition and featuring muscle relaxation as their basic pharmacological action." The fascinating history of curare is recounted, beginning with early encounters by the Spanish Conquistadores through its use as arrow poisons by the forest tribes in hunting and warfare, its chemistry, ethnography, botany and pharmacology. A terminal section of this chapter treats the development of modern muscle relaxants. This chapter thus traces how curare-initially only a crude plant extract-has given rise to the widely used and very important neuromuscular blocking agents of today. The precise role of plant secondary metabolites and their interactions with insect herbivores have been focal points for research by chemists, botanists and entomologists for many years. Alkaloids and their glycosides are frequently involved as feeding deterrents. Chapter 2 treats the relationships between the chemistry of alkaloids in host plants and the effects that these compounds may have on insect herbivores. Interestingly, an alkaloid produced by a plant may manifest different effects on different insects.

Book Alkaloids

    Book Details:
  • Author : S. William Pelletier
  • Publisher :
  • Release : 1983
  • ISBN :
  • Pages : 312 pages

Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1983 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: