Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1983 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alkaloids Chemical and Biological Perspectives written by S.W. Pelletier and published by Elsevier. This book was released on 2001-12-03 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids: Chemical and Biological Perspectives, the 15th volume of the ACBP series, features four important reviews of research on alkaloids. Chapter 1 is the first comprehensive review of the carbon-13 and proton NMR shift assignments and physical constants of diterpene alkaloids and their derivatives. In addition to the catalogue of spectral and physical data, the chapter includes a table of the occurrences of these alkaloids in various plant species, tables containing molecular formulas versus calculated high-resolution mass values, and calculated high-resolution mass values versus the molecular formulas of diterpenoid alkaloids, as well as seven tables summarizing the carbon-13 chemical shifts of various functional groups in diterpenoid alkaloids. Chapter 2 is a fascinating review of the supercritical fluid extraction of alkaloids. This technique using basic modifiers, provides an alternative method for the extraction of alkaloids. Chapter 3 summarizes recent advances in the synthesis of Amaryllidaceae alkaloids, an important class of naturally-occurring bases and neutral compounds. The increased activity in the synthesis of these alkaloids over the last decade is undoubtedly due to the fact that certain members of this family possess interesting and useful biological properties. Elegant syntheses, chiral and otherwise, of structures incorporating many asymmetric centres are reviewed. Chapter 4 reviews radical cyclization reactions in the total synthesis of indole alkaloids. The use of free radical chemistry in the synthesis of alkaloids has grown markedly because of the mild reaction conditions, tolerance of a wide variety of functional groups, and the good stereoselectivities. Each chapter in this volume has been reviewed by at least one specialist in the field.
Download or read book Alkaloids Secrets of Life written by Tadeusz Aniszewski and published by Elsevier. This book was released on 2007-03-22 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alkaloids, represent a group of interesting and complex chemical compounds, produced by the secondary metabolism of living organisms in different biotopes. They are relatively common chemicals in all kingdoms of living organisms in all environments. Two hundred years of scientific research has still not fully explained the connections between alkaloids and life.Alkaloids-Chemistry, Biological Significance, Applications and Ecological Role provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids. Considering an organic chemistry approach to alkaloids using biological and ecological explanation. Within the book several questions that persist in this field of research are approached as are some unresearched areas. The book provides beneficial text for an academic and professional audience and serves as a source of knowledge for anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices are included, as are a listing of alkaloids, plants containing alkaloids and some basic protocols of alkaloid analysis.* Presents the ecological role of alkaloids in nature and ecosystems * Interdisciplinary and reader friendly approach* Up-to-date knowledge
Download or read book Alkaloids Chemical and Biological Perspectives written by S. William Pelletier and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 8 of this series presents four timely reviews on alkaloids: Chapter 1 is a magnificent and monumental review of curare, "a group of dart and/or arrow poisons varying in composition and featuring muscle relaxation as their basic pharmacological action." The fascinating history of curare is recounted, beginning with early encounters by the Spanish Conquistadores through its use as arrow poisons by the forest tribes in hunting and warfare, its chemistry, ethnography, botany and pharmacology. A terminal section of this chapter treats the development of modern muscle relaxants. This chapter thus traces how curare-initially only a crude plant extract-has given rise to the widely used and very important neuromuscular blocking agents of today. The precise role of plant secondary metabolites and their interactions with insect herbivores have been focal points for research by chemists, botanists and entomologists for many years. Alkaloids and their glycosides are frequently involved as feeding deterrents. Chapter 2 treats the relationships between the chemistry of alkaloids in host plants and the effects that these compounds may have on insect herbivores. Interestingly, an alkaloid produced by a plant may manifest different effects on different insects.
Download or read book Alkaloids Chemical and Biological Perspectives written by S.W. Pelletier and published by Elsevier. This book was released on 1996-12-12 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the Thalictrum alkaloids. Forty-six new alkaloids are described from fifteen species of the genus Thalictrum, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the Thalictrum alkaloids.Chapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: Taxus). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine.Chapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized.Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related nortropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing.Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.
Download or read book The Pyrrolizidine Alkaloids written by L. B. Bull and published by . This book was released on 1968 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alkaloids Chemical and Biological Perspectives written by S. William Pelletier and published by Springer Science & Business Media. This book was released on 2013-03-11 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 7 of Alkaloids: Chemical and Biological Perspectives appears under the aegis of a new publisher: the distinguished firm of Springer Verlag New York, Inc. This volume presents three timely reviews on alkaloids: Chapter 1 reviews the homoerythrina and related alkaloids. a group of compounds occurring in seventeen species that are native to countries bordering the western Pacific. Since the last review in 1981, the number of these alkaloids has doubled. Chapter 2 is a comprehensive review of the carbon-13 NMR spectros copy of steroidal alkaloids. Because more than 350 plant species have yielded steroidal alkaloids and these alkaloids exhibit a wide spectrum of biological activities, including teratogenicity, this catalog of spectral and physical data should prove very useful to workers in this field. Chapter 3 presents a detailed review of proton and carbon-I3 NMR shift assignments and physical constants of norditerpenoid alkaloids. This chap ter is an extensive supplement to the review that appeared in Volume 2 of this series. In addition to the catalog of spectral and physical data, this chapter includes tables of proton and carbon shift assignments, a table of the occurrence of alkaloids in plant species, an index of al1 X-ray crystal structure determinations of norditerpenoid alkaloids, and tables containing molecular formulas versus calculated high-resolution mass values and calculated high-resolution mass values versus molecular formulas of nor diterpenoid alkaloids. Each chapter in this volume has been reviewed by an expert in the field. Indexes for both subjects and organisms are provided.
Download or read book Alkaloids written by Joanna Kurek and published by BoD – Books on Demand. This book was released on 2019-11-13 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Alkaloids" is intended for by chemistry, biochemistry, pharmacy, and other medical students, biologists, chemists, biochemists, and other professionals involved in the field of alkaloids. All chapters in this book are written by professionals in the areas of alkaloid chemistry, biology, pharmacy, and other interesting applications. The chapters cover interesting and less obvious information about different groups of alkaloids.
Download or read book Biological Activities of Alkaloids written by Sabino Aurelio Bufo and published by MDPI. This book was released on 2020-05-13 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products are increasingly attracting attention from both basic and applied science. Plant secondary metabolites, especially alkaloids, are receiving interest from a wide range of researchers due to their biological activity. They are produced to protect plants from diseases and herbivores. Therefore, they reveal a toxic activity that affects organisms at various levels of biological organization. A growing amount of research is proving their antimicrobial, antifungal, insecticidal, and anticancer activities. That makes them applicable in various fields from medicine, to pharmacology, veterinary, and toxicology, to crop protection. This Special Issue of Toxins, “Biological Activities of Alkaloids: From Toxicology to Pharmacology", collects 15 manuscripts describing the ecological, biological, pharmacological, and toxicological effects as well as structural and analytical aspects of plant alkaloids, their mode of action, and possible application in veterinary, medicine, and plant protection. These studies prove the potential for alkaloid application in various areas of science.
Download or read book Alkaloids written by S. William Pelletier and published by . This book was released on 1996 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the Thalictrum alkaloids. Forty-six new alkaloids are described from fifteen species of the genus Thalictrum, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the Thalictrum alkaloids. Chapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: Taxus). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine. Chapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized. Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related nortropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing. Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.
Download or read book Alkaloids written by Margaret F. Roberts and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since the late 1970s has a single work presented the biology of this heterogenous group of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the field, presents both the historical use of alkaloids and the latest discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and current medicinal use . Highlights include chapters on the chemical ecology of alkaloids in host-predator interactions, and on the compartmentation of alkaloids synthesis, transport, and storage. Extensive cross-referencing in tabular format makes this volume an excellent reference.
Download or read book Recent Advances in Natural Products Analysis written by Seyed Mohammad Nabavi and published by Elsevier. This book was released on 2020-03-07 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Natural Products Analysis is a thorough guide to the latest analytical methods used for identifying and studying bioactive phytochemicals and other natural products. Chemical compounds, such as flavonoids, alkaloids, carotenoids and saponins are examined, highlighting the many techniques for studying their properties. Each chapter is devoted to a compound category, beginning with the underlying chemical properties of the main components followed by techniques of extraction, purification and fractionation, and then techniques of identification and quantification. Biological activities, possible interactions, levels found in plants, the effects of processing, and current and potential industrial applications are also included. - Focuses on the latest analytical techniques used for studying phytochemical and other biological compounds - Authored and edited by the top worldwide experts in their field - Discusses the current and potential applications and predicts future trends of each compound group
Download or read book Alkaloids written by S. William Pelletier and published by Wiley-Interscience. This book was released on 1986-08-27 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: For centuries, human inhabitants of Central and South America have poisoned blow darts with alkaloids they extract from the brightly coloured frogs of the rain forests. Volume 4 of
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Plant Secondary Metabolism written by David S. Seigler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.
Download or read book Alkaloids written by S. William Pelletier and published by Wiley. This book was released on 1983-01-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Secondary Metabolite Biosynthesis and Metabolism written by American Chemical Society and published by Springer Science & Business Media. This book was released on 1992 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of an American Chemical Society symposium on Biosynthesis and Metabolism of Secondary Metabolite Natural Products, held April 1991, in Atlanta, Georgia. Bridging the gap between the fields of mechanistic bio-organic chemistry and biotechnology, contributions are in four main areas: antib
