Download or read book Alkaline Phosphatases in Biological Calcification written by Gösta Granström and published by . This book was released on 1977 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcification in Biological Systems written by Ermanno Bonucci and published by CRC Press. This book was released on 2020-07-24 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcification in Biological Systems provides a collection of up-to-date papers regarding calcification in a variety of biological systems. The papers are not simple reviews of the literature. Each paper reflects the personal experience of the author(s) and is rich in constructive criticism and suggestions. Topics range from basic molecular processes to general structural problems in systems as different as unicellular organisms and human skeletal tissues. Because calcification is so diffuse in the animal kingdom, this book makes no attempt to achieve a conclusive synthesis of available results and current ideas. Instead, its merit lies in its ability to be useful to investigators with different scientific backgrounds and areas of interest.
Download or read book Calcification in Biological Systems written by American Association for the Advancement of Science and published by . This book was released on 1960 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Calcification written by Ermanno Bonucci and published by Springer Science & Business Media. This book was released on 2007-02-17 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time, this book offers a critical review of the calcification process of the organic and inorganic phases of mineralized tissues focusing on the earliest phases. It includes a methodological chapter which provides the necessary practical information for making appropriate choices. The book is set to become an important reference source for the shelves of bone densitometry labs across the world.
Download or read book Mammalian Alkaline Phosphatases written by José Luis Millan and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: * The structure, regulation and expression of the AP genes * The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes * The phenotypic abnormalities of the different AP knockout mice * Our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
Download or read book Calcification and Physiology written by Geoffrey Bourne and published by Elsevier. This book was released on 2012-12-02 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry and Physiology of Bone, Second Edition: Volume IV: Calcification and Physiology explores the biochemical and physiological aspects of bone calcification. It discusses the comparative physiology of bone, the organelles involved in the local mechanism of calcification, bone tracer uptake and removal, and matrix vesicles of cartilage and bone. It explains the parathyroid biosynthesis and metabolism, cellular and humoral factors in bone resorption, electrical properties of bone, circulation in relation to bone growth and metabolism, and dentin and bone formation. Organized into 12 chapters, this edition begins with an overview of noncalcifying matrix and its conversion to calcifiable matrix, impregnation of collagen, and extraskeletal calcification. The remaining chapters focus on the effects of pyrophosphate and diphosphonates on calcium metabolism and skeletal turnover, calcium kinetics in plasma, the method matrix vesicles use in initiating calcification, the chemistry of parathyroid biosynthesis and metabolism, and mammalian osteopetrosis as a model for investigating cellular and humoral factors involved in bone resorption. It also discusses the use of electron spin resonance spectrometry in studying mineralized tissues, electrical response in flexed wet bone, bone blood volume and flow, and origin and fate of bone cells. The book concludes with a chapter on the biogenesis of matrix and mineral components of dentin and bone tissues. This book is highly recommended to biochemists, cell biologists, physiologists, anatomists, orthopedists, pathologists, clinicians, biomedical engineers, graduate students, professors, and others interested in the calcification and physiology of bone.
Download or read book Alkaline Phosphatase and Calcification written by Erik Henrichsen and published by . This book was released on 1958 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bone and Biomineralization written by Kenneth Simkiss and published by Hodder Education. This book was released on 1975 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phosphatase Modulators written by José Luis Millán and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts.
Download or read book Calcium Orthophosphates written by Sergey V. Dorozhkin and published by CRC Press. This book was released on 2012-06-04 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha
Download or read book Phosphate Metabolism written by Shaul Massry and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.
Download or read book Therapeutic Enzymes Function and Clinical Implications written by Nikolaos Labrou and published by Springer Nature. This book was released on 2019-09-03 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
Download or read book Calcification in Biological Systems written by Ermanno Bonucci and published by CRC Press. This book was released on 2020-07-24 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcification in Biological Systems provides a collection of up-to-date papers regarding calcification in a variety of biological systems. The papers are not simple reviews of the literature. Each paper reflects the personal experience of the author(s) and is rich in constructive criticism and suggestions. Topics range from basic molecular processes to general structural problems in systems as different as unicellular organisms and human skeletal tissues. Because calcification is so diffuse in the animal kingdom, this book makes no attempt to achieve a conclusive synthesis of available results and current ideas. Instead, its merit lies in its ability to be useful to investigators with different scientific backgrounds and areas of interest.
Download or read book Ocean Acidification written by National Research Council and published by National Academies Press. This book was released on 2010-09-14 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ocean has absorbed a significant portion of all human-made carbon dioxide emissions. This benefits human society by moderating the rate of climate change, but also causes unprecedented changes to ocean chemistry. Carbon dioxide taken up by the ocean decreases the pH of the water and leads to a suite of chemical changes collectively known as ocean acidification. The long term consequences of ocean acidification are not known, but are expected to result in changes to many ecosystems and the services they provide to society. Ocean Acidification: A National Strategy to Meet the Challenges of a Changing Ocean reviews the current state of knowledge, explores gaps in understanding, and identifies several key findings. Like climate change, ocean acidification is a growing global problem that will intensify with continued CO2 emissions and has the potential to change marine ecosystems and affect benefits to society. The federal government has taken positive initial steps by developing a national ocean acidification program, but more information is needed to fully understand and address the threat that ocean acidification may pose to marine ecosystems and the services they provide. In addition, a global observation network of chemical and biological sensors is needed to monitor changes in ocean conditions attributable to acidification.
Download or read book Calcium in Human Biology written by B.E.C. Nordin and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium in Human Biology provides an authoritative review of current knowledge and points the way to further progress in the understanding of this essential nutrient. In addition to considering the established importance of an adequate dietary source of available calcium for the formation of sound bones and teeth, there is detailed discussion of the part calcium plays in a variety of aspects of human metabolism. The book is written primarily for those working in the nutritional sciences and related fields. It will also be of interest to clinicians, nutritionists, and to those interested more generally in the biological sciences, as well as to those in the important sectors of the food industry which utilise or produce dairy products and other foods significant to the supply of dietary calcium.
Download or read book Metabolic Bone Disease and Clinically Related Disorders written by Louis V. Avioli and published by Academic Press. This book was released on 1997-10-08 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Bone Disease, Third Edition is the new, expanded edition of the classic text, featuring the latest advancements and research information in this fast-moving field. The Third Edition includes the most up-to-date information on molecular mechanisms, basic biology, pathophysiology, and diagnosis and management strategies of metabolic bone disease. Edited by "fathers of the field" An expanded version of a classic AP text Complete coverage of a fast-growing field
Download or read book Calcium Phosphates in Biological and Industrial Systems written by Zahid Amjad and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Phosphates in Biological and Industrial Systems provides a comprehensive discussion on calcium phosphates in the diverse areas of their applications. The authors are all respected specialists in their particular fields, possessing wide knowledge and experience and able to analyze recent results and relate them to their respective areas of expertise. New information, as well as a review of current concepts, highlights the individual contributions. Due to the broad scope of the subject covered and the large number of contributions, this book is divided into three parts. Whilst each section contains a basic theme, there is a considerable overlapping of ideas and approaches. This reflects the excitement and interdisciplinary nature of investigations by researchers interested in dissimilar aspects of calcium phosphates. Considering the general interest in calcium phosphates, Calcium Phosphates in Biological and Industrial Systems is directed at an audience of researchers in the fields of biology, chemistry, dentistry, geology, chemical engineering, environmental engineering, and medicine. It will also be useful to technology-focused researchers in industry whose investigations might be related directly or indirectly to calcium phosphates.
