Download or read book Algorithms for Sample Preparation with Microfluidic Lab on Chip written by Sukanta Bhattacharjee and published by CRC Press. This book was released on 2022-09-01 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent microfluidic technologies have brought a complete paradigm shift in automating biochemical processing on a tiny lab-on-chip (a.k.a. biochip) that replaces expensive and bulky instruments traditionally used in implementing bench-top laboratory protocols. Biochips have already made a profound impact on various application domains such as clinical diagnostics, DNA analysis, genetic engineering, and drug discovery, among others. They are capable of precisely manipulating micro-/pico-liter quantities of fluids, and provide integrated support for mixing, storage, transportation, and sensing, on-chip. In almost all bioprotocols, sample preparation plays an important role, which includes dilution and mixing of several fluids satisfying certain volumetric ratios. However, designing algorithms that minimize reactant-cost and sample-preparation time suited for microfluidic chips poses a great challenge from the perspective of protocol mapping, scheduling, and physical design. Algorithms for Sample Preparation with Microfluidic Lab-on-Chip attempts to bridge the widening gap between biologists and engineers by introducing, from the fundamentals, several state-of-the-art computer-aided-design (CAD) algorithms for sample preparation with digital and flow-based microfluidic biochips. Technical topics discussed in the book include: Basics of digital and flow-based microfluidic lab-on-chipComprehensive review of state-of-the-art sample preparation algorithmsSample-preparation algorithms for digital microfluidic lab-on-chipSample-preparation algorithms for flow-based microfluidic lab-on-chip
Download or read book Error Tolerant Biochemical Sample Preparation with Microfluidic Lab on Chip written by Sudip Poddar and published by CRC Press. This book was released on 2022-07-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.
Download or read book WALCOM Algorithms and Computation written by M. Sohel Rahman and published by Springer Nature. This book was released on 2020-01-27 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 14th International Conference on Algorithms and Computation, WALCOM 2020, held in Singapore in March/April 2020. The 23 full and 4 short papers presented were carefully reviewed and selected from 66 submissions. The papers focus on algorithmic graph theory and combinatorics, computational biology, computational geometry, data structures, experimental algorithm methodologies, graph algorithms, graph drawing, parallel and distributed algorithms, network optimization.
Download or read book Microfluidic Lab on a Chip for Chemical and Biological Analysis and Discovery written by Paul C.H. Li and published by CRC Press. This book was released on 2005-11-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microfluidic lab-on-a-chip allows scientists to conduct chemical and biochemical analysis in a miniaturized format so small that properties and effects are successfully enhanced, and processes seamlessly integrated. This microscale advantage translates into greater sensitivity, more accurate results, and better information. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery focuses on all aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations, and its breakthroughs over the years. It emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays and enzymatic assays. Originally conceived as a single chapter published in Ewing's Analytical Instrumentation, this book is a gateway to the vast literature and conference proceedings on the topic. Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery expands upon its roots to present a comprehensive treatment of microfluidic lab-on-a-chip methods and applications for novices and advanced researchers alike.
Download or read book Micro Electrode Dot Array Digital Microfluidic Biochips written by Zipeng Li and published by Springer. This book was released on 2018-12-14 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.
Download or read book Digital Microfluidic Biochips written by Krishnendu Chakrabarty and published by CRC Press. This book was released on 2018-10-03 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.
Download or read book Emerging Electronic Devices Circuits and Systems written by Chandan Giri and published by Springer Nature. This book was released on 2023-06-01 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book constitutes peer-reviewed proceedings of a workshop on Emerging Electronics Devices, Circuits, and Systems (EEDCS) held in conjunction with International Symposium on Devices, Circuits, and Systems (ISDCS 2022). The book focuses on the recent development in devices, circuits, and systems. It also discusses innovations, trends, practical challenges, and solutions adopted in device design, modeling, fabrication, characterization, and their circuit implementation with pertinent system applications. It will be useful for researchers, developers, engineers, academicians, and students.
Download or read book Proceedings of the International Conference on Computational Intelligence and Sustainable Technologies written by Kedar Nath Das and published by Springer Nature. This book was released on 2022-02-12 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the collection of the accepted research papers presented in the 1st ‘International Conference on Computational Intelligence and Sustainable Technologies (ICoCIST-2021)’. This edited book contains the articles related to the themes on artificial intelligence in machine learning, big data analysis, soft computing techniques, pattern recognitions, sustainable infrastructural development, sustainable grid computing and innovative technology for societal development, renewable energy, and innovations in Internet of Things (IoT).
Download or read book Algorithms and Complexity written by Pinar Heggernes and published by Springer. This book was released on 2019-05-20 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed conference proceedings of the 11th International Conference on Algorithms and Complexity, CIAC 2019, held in Rome, Italy, in May 2019. The 30 full papers were carefully reviewed and selected from 95 submissions. The International Conference on Algorithms and Complexity is intended to provide a forum for researchers working in all aspects of computational complexity and the use, design, analysis and experimentation of efficient algorithms and data structures. The papers present original research in the theory and applications of algorithms and computational complexity.
Download or read book Microfluidic Diagnostics written by Gareth Jenkins and published by Humana Press. This book was released on 2013-01-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic techniques are becoming widely incorporated into medical diagnostic systems due to the inherent advantages of miniaturization. In Microfluidic Diagnostics: Methods in Molecular Biology, researchers in the field detail methods and protocols covering subjects such as microfluidic device fabrication, on-chip sample preparation, diagnostic applications and detection methodologies. The protocols described range from cutting-edge developments to established techniques and basic demonstrations suitable for education and training; from basic fabrication methods to commercializing research. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microfluidic Diagnostics: Methods in Molecular Biology seeks to aid scientists in the further development and commercialization of microfluidic diagnostic technologies
Download or read book Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery written by Paul C. H. Li and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Lab-on-a-chip technology permits us to make many important discoveries that can only be observed at the microscale or the nanoscale. Using this technology, biological and biochemical analyses translate into greater sensitivity, more accurate results, and more valuable findings. Authored by one of the fields pioneering researchers, Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery focuses on all key aspects of microfluidic lab-on-a-chip technologies to offer an exceptionally cohesive overview of the science, its limitations, breakthroughs made over the years, and currently emerging advances. The book emphasizes analytical applications of microfluidic technology and offers in-depth coverage of micromachining methods, microfluidic operations, chemical separations, sample preparation and injection methods, detection technology, and various chemical and biological analyses. Other topics of interest include the use of polymeric chips, fluid flow valve and control, single-cell analysis, DNA and RNA amplification techniques, DNA hybridization, immunoassays, and enzymatic assays. The book includes more than 300 figures that depict novel chip functions and breakthroughs and 16 tables summarize materials and refer readers to additional resources. An appendix compiles extensive analytical applications from emerging and established research groups. Beginners in the field will find the book useful for navigating the vast literature related to the technology, while experienced researchers will rely on the compiled information for easy comparison and references for further study. Derived from the highly popular Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery (2006), this volume is also readily adaptable for classroom use. Problem sets in each chapter help students test their assimilation of the material and clarify challenging conce.
Download or read book Applied Algorithms written by Prosenjit Gupta and published by Springer. This book was released on 2014-01-08 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the First International Conference on Applied Algorithms, ICAA 2014, held in Kolkata, India, in January 2014. ICAA is a new conference series with a mission to provide a quality forum for researchers working in applied algorithms. Papers presenting original contributions related to the design, analysis, implementation and experimental evaluation of efficient algorithms and data structures for problems with relevant real-world applications were sought, ideally bridging the gap between academia and industry. The 21 revised full papers presented together with 7 short papers were carefully reviewed and selected from 122 submissions.
Download or read book Exact Design of Digital Microfluidic Biochips written by Oliver Keszocze and published by Springer. This book was released on 2018-06-11 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents exact, that is minimal, solutions to individual steps in the design process for Digital Microfluidic Biochips (DMFBs), as well as a one-pass approach that combines all these steps in a single process. All of the approaches discussed are based on a formal model that can easily be extended to cope with further design problems. In addition to the exact methods, heuristic approaches are provided and the complexity classes of various design problems are determined. Presents exact methods to tackle a variety of design problems for Digital Microfluidic Biochips (DMFBs); Describes an holistic, one-pass approach solving different design steps all at once; Based on a formal model of DMFBs that is easily adaptable to deal with further design tasks.
Download or read book Advanced Computing and Systems for Security written by Rituparna Chaki and published by Springer Nature. This book was released on 2019-08-28 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features extended versions of selected papers that were presented and discussed at the 6th International Doctoral Symposium on Applied Computation and Security Systems (ACSS 2019) held in Kolkata, India on 12–13 March, 2019. Organized by the Departments of Computer Science & Engineering and A.K. Choudhury School of Information Technology, both from the University of Calcutta, the symposium’s international partners were Ca' Foscari University of Venice, Italy and Bialystok University of Technology, Poland. The chapters cover topics such as biometrics, image processing, pattern recognition, algorithms, cloud computing, wireless sensor networks and security systems, reflecting the various symposium sessions.
Download or read book Intelligent Technologies Concepts Applications and Future Directions written by Satya Ranjan Dash and published by Springer Nature. This book was released on 2022-05-21 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses automated computing systems which are mostly powered by intelligent technologies like artificial intelligence, machine learning, image recognition, speech processing, cloud computing, etc., to perform complex automated tasks which are not possible by traditional computing systems. The chapters are extended version of research works presented at first Ph.D. Research Symposium in various advanced technologies used in the field of computer science. This book provides an opportunity for the researchers to get ideas regarding the ongoing works that help them in formulating problems of their interest. The academicians can also be benefited to know about the current research trends that smooth the way to guide their students to carry out research work in the proper direction. The industry people will be also facilitated to know about the current advances in research work and materialize the research work into industrial applications.
Download or read book Languages Design Methods and Tools for Electronic System Design written by Tom J. Kazmierski and published by Springer Nature. This book was released on 2019-12-20 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together a selection of the best papers from the twenty-first edition of the Forum on specification and Design Languages Conference (FDL), which took place on September 10-12, 2018, in Munich, Germany. FDL is a well-established international forum devoted to dissemination of research results, practical experiences and new ideas in the application of specification, design and verification languages to the design, modeling and verification of integrated circuits, complex hardware/software embedded systems, and mixed-technology systems. Covers Assertion Based Design, Verification & Debug; Includes language-based modeling and design techniques for embedded systems; Covers design, modeling and verification of mixed physical domain and mixed signal systems that include significant analog parts in electrical and non-electrical domains; Includes formal and semi-formal system level design methods for complex embedded systems based on the Unified Modelling Language (UML) and Model Driven Engineering (MDE).
Download or read book Secure and Trustworthy Cyberphysical Microfluidic Biochips written by Jack Tang and published by Springer. This book was released on 2019-05-28 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes novel hardware security and microfluidic biochip design methodologies to protect against tampering attacks in cyberphysical microfluidic biochips (CPMBs). It also provides a general overview of this nascent area of research, which will prove to be a vital resource for practitioners in the field.This book shows how hardware-based countermeasures and design innovations can be a simple and effective last line of defense, demonstrating that it is no longer justifiable to ignore security and trust in the design phase of biochips.
