Download or read book Alcohol and Abnormal Protein Biosynthesis written by Marcus A. Rothschild and published by Elsevier. This book was released on 2014-05-17 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol and Abnormal Protein Biosynthesis: Biochemical and Clinical focuses on the methods for measuring protein metabolism and the effects of alcohol and altered protein intake as they affect the heart, liver, skeletal muscle, and the brain. Organized into six sections, this book begins with an overview on malnutrition and alcoholism, as well as available techniques for the study of protein synthesis. Subsequent section details the adaptation of protein synthesis and transport to alcohol and malnutrition. Section three discusses the skeletal and cardiac muscle protein metabolism. The last three sections describe the reaction of hepatic protein synthesis to malnutrition and alcohol; effects of alcohol on brain RNA metabolism; and alcohol associated cardiac and hepatic disease.
Download or read book Alcohol and Protein Synthesis written by and published by . This book was released on 1983 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The proceedings of a 1980 workshop presents 19 expert papers on various aspects of the effect of alcohol (ethanol) intake on in vivo protein biosynthesis. The papers are grouped among 3 principal themes: 1) the effects of alcohol on the biosynthesis of brain protein and nucleic acid macromolecules; 2) the effects of ethanol on eukaryotic protein biosynthesis; and 3) biobehavioral and cellular studies on ethanol effects. The adverse consequences of maternal alcoholism on fetal protein metabolism and the neurological aspects and complications of alcoholism also are addressed. (wz).
Download or read book Alcohol and Protein Synthesis written by U.S. National Institute on Alcohol Abuse and Alcoholism and published by . This book was released on 1983 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Protein Synthesis written by U.S. National Institute on Alcohol Abuse and Alcoholism and published by . This book was released on 1983 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol Effects on Protein Synthesis in Rat Hepatoma Cells written by Melika M. Davis and published by . This book was released on 1989 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Protein Synthesis written by University of California. College of Medicine and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effect of Phenethyl Alcohol on Protein Synthesis in Escherichia Coli written by Joseph William Zilinsky and published by . This book was released on 1967 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Resistance Exercise and Alcohol written by Danielle E. Levitt and published by . This book was released on 2018 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance exercise (RE) training is a well-known and effective method for promoting increases in muscle mass and strength. A single bout of RE induces physiological disturbances that require coordinated activation of the immune system and intramuscular signaling in order to return the tissue to homeostasis and adapt to the RE challenge. On the other hand, acute binge alcohol consumption can affect the immune response to an inflammatory challenge, intramuscular anabolic signaling, and muscle protein synthesis, and the effects of alcohol on these processes are opposite that of RE. Furthermore, individuals who report more frequent exercise also report a greater frequency of binge drinking. However, few investigations exist regarding the effects of binge alcohol consumed after a bout of RE on RE-induced physiological changes and performance recovery. Therefore, the overarching purpose of the investigations contained within this dissertation was to investigate the effect of alcohol consumed after RE on the RE-induced changes in mTOR pathway signaling, muscle protein synthesis, inflammatory capacity, strength recovery, and power recovery. Although RE increased mTOR pathway signaling and inflammatory capacity after exercise and reduced maximal strength and explosive power the day after exercise, we observed no effects of alcohol (1.09 g ethanol∙kg-1 lean body mass, designed to result in a peak blood alcohol concentration of approximately 0.12 g∙dl-1) consumed after RE on mTOR pathway signaling, 24-hour rates of muscle protein synthesis, inflammatory capacity, or strength and power recovery in resistance-trained individuals.
Download or read book Nutrition and Alcoholthe CRC Series in Physiology of Drug Abuse written by Ronald Ross Watson and published by CRC Press. This book was released on 1992-09-03 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition and Alcohol provides a comprehensive summary of the latest research data available on the effects of alcohol on the nutritional state of alcohol abusers. Data illustrating the combined effects of direct alcohol toxicity together with the ill effects of malnutrition on tissue damage are emphasized. The book is oriented toward clinicians and basic scientist-researchers.
Download or read book Alcohol Related Diseases in Gastroenterology written by Helmut K. Seitz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse ranks among the most common and also the most severe environmental hazards to human health. Its significance is heightened by the possibility of prevention by elimination of the habit, however, rarely exerted. The incidence of deleterious effects on human health has relentlessly risen in the past years for a variety of factors. They include migration of populations and, particularly, increased urbanization. Thus, in some parts of the world, population groups previously spared have become involved, which is also re flected in the increasing number of breweries and distilleries in the developing countries. Social, religious, and gender-related barriers to alcohol consumption are loosening, and the financial improvement of some segments of populations now enable them to buy alcoholic beverages. Thus the greatest percentage rise in the United States has recently been in black women. Adolescents and young people drink more alcoholic beverages than ever, and growing alcohol abuse by pregnant women has let to an increase of the incidence of the fetal alcohol syndrome. While the social and behavioral, including psychiatric, consequences of alcoholism are staggering, the gastrointestinal and, particularly, hepatic manifestations are the most widespread somatic effects, and chronic hepatic disease in alcoholics appears to cause the greatest cost to society. Indeed, mortality from liver cirrhosis is considered a reliable index of alcohol consumption in a country.
Download or read book Biochemical Correlates of Alcohol Tolerance Role of Cerebral Protein Synthesis written by Donna Dorothy Walczak and published by . This book was released on 1983 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of Low Protein Intake and Alcohol on Rat Placental Protein Synthesis written by Shahla Mozayani and published by . This book was released on 1978 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Inability of Glycine to Prevent Alcohol Induced Anabolic Resistance to Refeeding written by Blake Bridges and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcoholic myopathy is a wasting condition that effects skeletal muscle mass. One factor that may contribute to alcoholic myopathy is anabolic resistance which is induced by alcohol intake and leads to a suppression of protein synthesis following an anabolic stimulus. The purpose of this study was to assess the effects of glycine in a model of acute alcohol consumption and its ability to alter the anabolic resistant state induced by alcohol. The purpose of aim 1 was to establish whether refeeding significantly altered protein synthesis and components of the mTORC1 pathway when alcohol and or glycine was consumed It was hypothesized that there would be a refeeding affect and the treatment groups with EtOH present in the diet would not show increased signaling in protein synthesis or components of the mTORC1 pathway. To accomplish this, female mice were split into five treatment groups including Control-Fasted, Control-Refed, EtOH-Refed, Control-Refed+Glycine, and EtOH+Refed+Glycine. The Refed groups were fasted for 16 hours during the light cycle and provided food after the fast for 30 minutes. After 30 minutes of refeeding, food was removed and tissue collection of the Gastrocnemius occurred 30 minutes after the removal of food. Proteins and mRNA of the gastrocnemius were analyzed using Western blotting and RT-PCR techniques. A refeeding affect was found for mTORC1 substrates rpS6 S240/244 and Akt T308 in the Control-Refed group compared to the Control-Fasted group. The second aim of the study was to determine whether glycine would be able to prevent EtOH induced anabolic resistance. We hypothesized that glycine would diminish the effects of EtOH and restore levels of protein synthesis and mTOR1 signaling associated with refeeding that are reduced by alcohol. The same treatment groups were used as Aim 1 excluding the Control-Fasted group. Puromycin used to express protein synthesis, 4E-BP1 S65, and Akt T308 were reduced in the EtOH-glycine-refed group compared to the Control-Refed treatment group. A main effect of alcohol for reducing mTOR S2448, S6K1 T389, rpS6 240/244, and ULK1 S757 was also found, while glycine did not offset this effect. Therefore, glycine is an ineffective method of abating the anabolic resistant state induced through the consumption of alcohol.
Download or read book Studies on Liver Alcohol Dehydrogenase and Genetic Code and Protein Synthesis written by Charles Leon Woodley and published by . This book was released on 1972 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Alcohol and Protein Synthesis Ethanol Nucleic Acid and Protein Synthesis in the Brain and Other Organs written by National Institute on Alcohol Abuse and Alcoholism, Rockville, MD. and published by . This book was released on 1983 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Effects of Alcohol written by Henri Begleiter and published by Springer. This book was released on 1980-07-01 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disease of alcoholism has long been a major health problem which affects significant proportions of the populations of various countries. It is now apparent that legal and moral sanctions have not provided a sufficient impetus to arrest this rampant problem. Therefore, it is evident that the approach to this international health problem must rely on the development of efficacious prevention and treatment techniques. If the treatment and prevention of alcoholism is to be based on the rational assessment of the disease, it is imperative that we understand the complex determinants of this disease. The elements that initiate and perpetuate this addictive process must be examined and elucidated. Because this disease appears to involve biological, psychological and sociological factors, the need for multidisciplinary research is of the utmost importance.
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
