Download or read book Affinity Online written by Mizuko Ito and published by NYU Press. This book was released on 2018-12-18 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: How online affinity networks expand learning and opportunity for young people Boyband One Direction fanfiction writers, gamers who solve math problems together, Harry Potter fans who knit for a cause. Across subcultures and geographies, young fans have found each other and formed community online, learning from one another along the way. From these and other in-depth case studies of online affinity networks, Affinity Online considers how young people have found new opportunities for expanded learning in the digital age. These cases reveal the shared characteristics and unique cultures and practices of different online affinity networks, and how they support “connected learning”—learning that brings together youth interests, social activity, and accomplishment in civic, academic, and career relevant arenas. Although involvement in online communities is an established fixture of growing up in the networked age, participation in these spaces show how young people are actively taking up new media for their own engaged learning and social development. While providing a wealth of positive examples for how the online world provides new opportunities for learning, the book also examines the ways in which these communities still reproduce inequalities based on gender, race, and socioeconomic status. The book concludes with a set of concrete suggestions for how the positive learning opportunities offered by online communities could be made available to more young people, at school and at home. Affinity Online explores how online practices and networks bridge the divide between in-school and out-of-school learning, finding that online affinity networks are creating new spaces of opportunity for realizing the ideals of connected learning.
Download or read book Anthropological Perspectives on Tooth Morphology written by G. Richard Scott and published by Cambridge University Press. This book was released on 2013-02-21 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: This follow-up to The Anthropology of Modern Human Teeth puts methods to use in interpreting human origins and affinities.
Download or read book Long term Environmental Effects of Offshore Oil and Gas Development written by D.F. Boesch and published by CRC Press. This book was released on 1987-03-24 with total page 722 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-term Environmental Effects of Offshore Oil and Gas Development contains 14 chapters by different authors which focus on the US.
Download or read book Hemoglobin written by Jay F. Storz and published by . This book was released on 2019 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a synthesis of our current understanding of hemoglobin (Hb) function and evolution, and illustrates how research on this protein has provided more general insights into mechanisms of protein evolution and biochemical adaptation.
Download or read book Mechanisms of lymphocyte mediated cytotoxicity in health and disease written by Cosima T. Baldari and published by Frontiers Media SA. This book was released on 2023-06-29 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Elements of Thermal Chemistry written by Matthew Moncrieff Pattison Muir and published by . This book was released on 1885 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Interactive Qualitative Analysis written by Norvell Northcutt and published by SAGE. This book was released on 2004-02-20 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at helping students unscramble the mysteries of qualitative data collection, coding, and analysis, this book integrates and reconciles theory and methods by showing how to use a systematic, qualitative technique: interactive qualitative analysis.
Download or read book Structural Biology in Immunology written by Chaim Putterman and published by Academic Press. This book was released on 2018-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. - Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules - Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship - Features a collaborative editorial effort, involving clinical immunologists and structural biologists - Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology - Gives interested parties a bridge to learn about computer modeling and structure based design principles
Download or read book The Foreign Policies of Arab States written by ʻAlī al-Dīn Hilāl and published by American Univ in Cairo Press. This book was released on 2010 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an indispensable aid for those studying or teaching the foreign policies of the contemporary Middle East. Not only are the elements of foreign policy discussed and presented as a whole region, but the editors provide the established analytical framework by which each contributor, in their individual chapters, has analyzed and evaluated the foreign policies of nine Arab countries. Their framework perceives foreign policy in the context of its environment : domestic, regional and global. This edition has new material reflecting the earth-shaking events at the end of the Cold War and the continuation of violence and terrorism.
Download or read book Monograph on the Lias Ammonites of the British Islands written by Thomas Wright and published by . This book was released on 1886 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proteins written by Thomas E. Creighton and published by Macmillan. This book was released on 1993 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on a combined basis of chronology and of structural and functional hierarchy, This comprehensive text describes all aspects of proteins--biosynthesis, evolution, dynamics, ligand binding, catalysis, and energy transduction--not just their structures. This edition (first was 1984) is thoroughly updated--especially in the area of protein biosynthesis--and features end-of-chapter exercises and problems, many of which require the student to consult the cited literature in order to obtain the answer. Annotation copyright by Book News, Inc., Portland, OR
Download or read book The Pharmacology of Alcohol and Alcohol Dependence written by Henri Begleiter and published by . This book was released on 1996 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.
Download or read book Strategic Interpersonal Communication written by John A. Daly and published by Routledge. This book was released on 2013-01-11 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses how people go about achieving their social goals through human symbolic interaction. The editors' collective presumption is that there are more or less typical ways that people attempt to obtain desired outcomes -- be they persuasive, informative, conflictive, or the like -- through communication. Representing a first summary of research done by scholars, primarily in the communication discipline, this volume seeks to identify and understand how it is that people achieve what they want through social interaction. Under the very broad label of strategies, this research has sought to: * identify critical social goals such as gaining compliance, generating affinity, resolving social conflict, and offering information; * specify, for each goal, the ways, or strategies, by which people can go about achieving these goals; * determine predictors of strategy selection -- that is, why does a person opt for one strategy over others to obtain the desired end? The research also reflects the attention the field of communication has given to strategy issues in the past 15 years. The chapters describe research on the ways in which people achieve different goals, and summarize existing research and theory on the attainment of social goals. Readers will gain insight into many of the issues that exist regardless of the strategy being discussed. Thus, this volume may not include chapters on topics such as ways people elicit or offer disclosure, ways people demonstrate anger, or ways people create guilt, but the issues that appear consistently throughout the various chapters should apply equally to these. Finally, the essays in this volume provide not only a summary of what has been accomplished to date, but also an initial theoretic map for future research concerning strategic interpersonal communication.
Download or read book Immune system modeling and analysis written by Ramit Mehr and published by Frontiers Media SA. This book was released on 2015-04-22 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid development of new methods for immunological data collection – from multicolor flow cytometry, through single-cell imaging, to deep sequencing – presents us now, for the first time, with the ability to analyze and compare large amounts of immunological data in health, aging and disease. The exponential growth of these datasets, however, challenges the theoretical immunology community to develop methods for data organization and analysis. Furthermore, the need to test hypotheses regarding immune function, and generate predictions regarding the outcomes of medical interventions, necessitates the development of mathematical and computational models covering processes on multiple scales, from the genetic and molecular to the cellular and system scales. The last few decades have seen the development of methods for presentation and analysis of clonal repertoires (those of T and B lymphocytes) and phenotypic (surface-marker based) repertoires of all lymphocyte types, and for modeling the intricate network of molecular and cellular interactions within the immune systems. This e-Book, which has first appeared as a ‘Frontiers in Immunology’ research topic, provides a comprehensive, online, open access snapshot of the current state of the art on immune system modeling and analysis.
Download or read book Computational Drug Discovery written by Vasanthanathan Poongavanam and published by John Wiley & Sons. This book was released on 2024-01-19 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Drug Discovery A comprehensive resource that explains a wide array of computational technologies and methods driving innovation in drug discovery Computational Drug Discovery: Methods and Applications (2 volume set) covers a wide range of cutting-edge computational technologies and computational chemistry methods that are transforming drug discovery. The book delves into recent advances, particularly focusing on artificial intelligence (AI) and its application for protein structure prediction, AI-enabled virtual screening, and generative modeling for compound design. Additionally, it covers key technological advancements in computing such as quantum and cloud computing that are driving innovations in drug discovery. Furthermore, dedicated chapters that addresses the recent trends in the field of computer aided drug design, including ultra-large-scale virtual screening for hit identification, computational strategies for designing new therapeutic modalities like PROTACs and covalent inhibitors that target residues beyond cysteine are also presented. To offer the most up-to-date information on computational methods utilized in computational drug discovery, it covers chapters highlighting the use of molecular dynamics and other related methods, application of QM and QM/MM methods in computational drug design, and techniques for navigating and visualizing the chemical space, as well as leveraging big data to drive drug discovery efforts. The book is thoughtfully organized into eight thematic sections, each focusing on a specific computational method or technology applied to drug discovery. Authored by renowned experts from academia, pharmaceutical industry, and major drug discovery software providers, it offers an overview of the latest advances in computational drug discovery. Key topics covered in the book include: Application of molecular dynamics simulations and related approaches in drug discovery The application of QM, hybrid approaches such as QM/MM, and fragment molecular orbital framework for understanding protein-ligand interactions Adoption of artificial intelligence in pre-clinical drug discovery, encompassing protein structure prediction, generative modeling for de novo design, and virtual screening. Techniques for navigating and visualizing the chemical space, along with harnessing big data to drive drug discovery efforts. Methods for performing ultra-large-scale virtual screening for hit identification. Computational strategies for designing new therapeutic models, including PROTACs and molecular glues. In silico ADMET approaches for predicting a variety of pharmacokinetic and physicochemical endpoints. The role of computing technologies like quantum computing and cloud computing in accelerating drug discovery This book will provide readers an overview of the latest advancements in computational drug discovery and serve as a valuable resource for professionals engaged in drug discovery.
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2004-02-19 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
Download or read book A Handbook of Molecular Docking written by N.B. Singh and published by N.B. Singh. This book was released on with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Handbook of Molecular Docking is an accessible and comprehensive guide designed for absolute beginners. This book introduces the fundamental concepts and practical techniques of molecular docking, providing a step-by-step approach to understanding and performing docking studies. With a focus on clear explanations and non-mathematical descriptions, it covers essential topics such as molecular representations, docking algorithms, and the application of modern computational tools. Through illustrative examples and practical exercises, readers will gain the skills and confidence needed to explore the dynamic field of molecular docking and its applications in drug discovery and bioinformatics.
