Download or read book Advances in Strained and Interesting Organic Molecules written by B. Halton and published by JAI Press. This book was released on 1999-03-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides timely essays on the many facets of strained and interesting organic molecules. Contributions from experts in the field provide insights not only for the practicing organic chemist, but also for the student at the senior undergraduate and graduate level.
Download or read book Advances in Strained and Interesting Organic Molecules written by B. Halton and published by Elsevier. This book was released on 1999-12-27 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eighth volume of this series comprises six chapters and describes a variety of interesting strained and not so strained molecules and their use - or abuse - in the widest sense. This volume contains a position summary of planar carbon networks, the field of strained allenesis addressed by considering the five- to- nine-membered ring derivatives and this is followed by an introduction to the nature of carbene geometry and the use of ESR spectroscopy in deducing carbene structure. The use of strained molecules in the synthesis of important new compounds of a natural and non-natural nature is a main theme in the volume. Other areas that are discussed are strained carbohydrates, stereocontrolled access to natural products and polymer systems as well as a much sought after contribution to the series on small-ring nitrogen heterocycles.
Download or read book Advances in Strained and Interesting Organic Molecules written by Brian Halton and published by JAI Press(NY). This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of essays on the facets of strained organic molecules. It covers topics such as applications of ring strain in natural product synthesis and uses of the vacuum gas-solid reaction procedure in synthesis.
Download or read book Advances in Strained and Interesting Organic Molecules written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carbocyclic and Heterocyclic Cage Compounds and Their Building Blocks Synthesis Structure Mechanism and Theory written by K.K. Laali and published by JAI Press. This book was released on 1999-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbocyclic and Heterocyclic Cage Compounds and their Building Blocks is the first independent Supplement in the series. The collection of essays presented is very much at the forefront of research in this active area and the topics discussed complement and evolve from the more general treatment in earlier volumes of the Series. Furthermore it was appropriate to produce a collection of work at the cutting edge of the field, where progress in heterocyclic cage compounds are discussed together in a single volume, thus avoiding the organic versus organometallic barriers in an effort to raise more awareness concerning their similarities and differences. Since phosphaalkynes serve as building blocks for a host of phosphorus-carbon cage compounds discussion of the versatile chemistry of phosphaalkynes is relevant. Likewise, discussion of the versatile chemistry of phosphaalkenes is appropriate since they function as synthetic precursors to phosphaalkynes and are the products of electrophilic addition to phosphaalkynes.
Download or read book Advances in Strain in Organic Chemistry written by Brian Halton and published by Jai Press. This book was released on 1991 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collected essays which provide reviews and updates on many facets of strained organic molecules, and which aim to generate ideas for future theoretical and experimental research.
Download or read book Advances in Strained and Interesting Organic Molecules written by and published by . This book was released on 2000 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Physical Organic Chemistry written by and published by Academic Press. This book was released on 1989-06-05 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series, established by Victor Gold in 1963, brings before the chemical community substantial, authoritative, and considered reviews of areas of chemistry in which quantitative methods are used in the study of the structures of organic compounds and their relation to physical and chemical properties.Physical organic chemistry is viewed as a particular approach to scientific enquiry rather than a further intellectual specialization. Organometallic compounds are included, and relevant aspects of physical theoretical, inorganic, and biological chemistry are incorporated in reviews where appropriate.
Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
Download or read book Advances in Theoretically Interesting Molecules written by and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Theoretically Interesting Molecules written by Randolph P. Thummel and published by Jai Press. This book was released on 1992-07-01 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Theoretically Interesting Molecules...
Download or read book Strained Organic Molecules written by István Hargittai and published by Wiley-VCH. This book was released on 1991 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Harnessing Strain Driven Reactivity for Complex Molecule Synthesis and Advances in Chemical Education written by Jason Chari and published by . This book was released on 2022 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation describes the development of synthetic methodologies and approaches that leverage strain-driven reactivity to access complex molecules, as well as enzymatic studies and advances in the field of chemical education. The high potential energy stored within strained bonds offers a powerful tool in organic synthesis for the construction of new covalent bonds. Controlling the reactivity of strained molecules, while challenging in many cases, offers a means to form multiple bonds in a single step, under mild reaction conditions, and generate products that may be inaccessible by other means. Herein, several synthetic endeavors are described that seek to leverage strain release to push our understanding of chemical reactivity and gain new entryways into important classes of organic and organometallic compounds. Moreover, two studies in the area of biosynthesis and are described, which take advantage of synergy between chemical synthesis and enzymatic chemistry to access bioactive compounds with high selectivity. Finally, studies in the area of chemical education are described. These efforts seek to make organic chemistry accessible to wider audiences through the development of interactive, globally available educational tools and the creation of a new undergraduate lecture course that highlights the role of organic chemistry in the world around us. Chapter one describes a perspective on the field of complex molecule synthesis (i.e., total synthesis), with a focus on the power of collaborations across research groups. Although historically competitive, there is a growing spirit of teamwork and collaboration in the field of total synthesis. This chapter discusses recent breakthroughs in both academic and industrial laboratories that have succeeded as a direct result of alliances between research groups. Chapter two describes progress toward the total synthesis of dodecahedrane, a complex and highly symmetrical hydrocarbon that bears twelve fused rings arranged in a cage-like architecture. Central to our approach is an ambitious [2+2+2+2+2] poly-ene cyclization cascade which would serve to provide new insights into chemical reactivity. Current efforts center around constructing key linkages found in the target by harnessing the strain release of norbornene ring systems to form new carbon-carbon bonds. Chapter three describes a concise and scalable synthetic approach to precursors to strained intermediates. Although historically avoided due to their high reactivity, strained cyclic alkynes and allenes have demonstrated value in the synthesis of medicinally privileged, polycyclic compounds. These efforts, which provide efficient access to silyl triflate precursors to cyclohexyne and 1,2-cyclohexadiene, serve to enable further studies involving strained alkynes and allenes. Chapters four and five describe the development of new methodologies that exploit strained aryne intermediates in the synthesis of complex organic and organometallic materials. Both chapters investigate the controlled generation and reactivity of aryne intermediates, as well as engagement of these intermediates in Pd-catalysis to build new ring systems. Chapter four specifically details the development of aryne chemistry "on-the-complex," wherein fleeting aryne intermediates are reacted with pre-coordinated metal-ligand complexes to form new carbon-carbon bonds. These studies, performed in the context of privileged, photoactive polypyridyl metal complexes, provide an effective strategy to annulate organometallic complexes and access complex metal-ligand scaffolds, while furthering the synthetic utility of strained intermediates in chemical synthesis. Chapter five details the development of Pd-catalyzed reactions of indole and carbazole-based arynes (i.e., hetarynes) to access [pi]-extended heterocyclic materials. The products obtained were applied as ligands in two-coordinate metal complexes to access new OLED emitters. Chapters six and seven are concerned with uncovering and investigating highly selective reactions catalyzed by fungal enzymes. In particular, chapter six describes the discovery of two groups of enzymes that catalyze distinct reactions, an Alder-ene reaction (previously unknown in biology) and a stereoselective hetero-Diels-Alder reaction. Chapter seven presents studies pertaining to the aminoacylation and thiolation of polyketides in fungi, with a focus on elucidating mechanistic pathways. Both chapters showcase important synergy between chemical synthesis and enzymatic chemistry, and elucidate new enzymatic pathways that ultimately give rise to molecular complexity. Chapters eight and nine illustrate advances in chemical education. Chapter eight specifically details the development and execution of a new undergraduate course taught by graduate students. The course, entitled Catalysis in Modern Drug Discovery, served to highlight the central role of organic chemistry in drug discovery, while also conveying key concepts in catalysis. Moreover, the course spotlighted the various careers that organic chemists play in the development of new medicines. Chapter nine presents a perspective that highlights our recent efforts to develop interactive resources in chemical education for worldwide usage. In particular, these efforts seek to promote a spirit of innovation in chemical education and spur the development of widely accessible resources that improve learning outcomes and promote positive perception of chemistry in the broader community
Download or read book Strained Organic Molecules written by István Hargittai and published by . This book was released on 1991 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Nitrogen Heterocycles written by C.J. Moody and published by Elsevier. This book was released on 1999-01-19 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a range of topics such as the activation and manipulation of pyrroles, the synthesis of annelated pyrroles using acylation reactions and the synthesis of kainoids, a family of highly biologically active nitrogen heterocycles.
Download or read book Recent Developments Of Diazo Compounds In Organic Synthesis written by Di Qiu and published by World Scientific. This book was released on 2020-12-29 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diazo compounds are versatile substances with diverse transformations in organic synthesis and other fields. Studies of diazo compounds have been ongoing for a very long time but still attract significant attention within the organic chemistry community, with new papers related to diazo compounds appearing at a daily pace. Over the past twenty years, there have been over fifty reviews and accounts related to the reactions of diazo compounds, but most of them cover limited aspects of diazo compounds. In addition to organic synthesis, diazo compounds have found applications in interdisciplinary fields such as material sciences, chemical biology and also polymerization.In this comprehensive book, the authors cover the most recent advances in the fields related to diazo compounds, including the application of donor-acceptor carbenes, carbene-based cross-coupling reactions and polymerizations, as well as the breakthrough in catalytic asymmetric carbene O-H, S-H, and N-H bond insertions. They also cover the application of flow chemistry in diazo reactions. The authors aim to provide a contemporary and comprehensive review for investigators engaged in or with interest in diazo compounds to boost further developments in this fascinating field.
Download or read book Advanced Organic Chemistry written by Francis A. Carey and published by Springer Science & Business Media. This book was released on 2007-06-27 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part A covers fundamental structural topics and basic mechanistic types. It can stand-alone; together, with Part B: Reaction and Synthesis, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for study of structure, reaction and selectivity for students and exercise solutions for instructors.
