Download or read book Advances in Genetics Development and Evolution of Drosophila written by Seppo Lakovaara and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1906 Castle, Carpenter, Clarke, Mast, and Barrows published a paper entitled "The effects of inbreeding, cross-breeding, and selection upon the fertility and variability of Drosophila." This article, 55 pages long and published in the Proceedings of the Amer ican Academy, described experiments performed with Drosophila ampe lophila Lov, "a small dipterous insect known under various popular names such as the little fruit fly, pomace fly, vinegar fly, wine fly, and pickled fruit fly." This study, which was begun in 1901 and published in 1906, was the first published experimental study using Drosophila, subsequently known as Drosophila melanogaster Meigen. Of course, Drosophila was known before the experiments of Cas tles's group. The small flies swarming around grapes and wine pots have surely been known as long as wine has been produced. The honor of what was the first known misclassification of the fruit flies goes to Fabricius who named them Musca funebris in 1787. It was the Swedish dipterist, C.F. Fallen, who in 1823 changed the name of ~ funebris to Drosophila funebris which was heralding the beginning of the genus Drosophila. Present-day Drosophila research was started just 80 years ago and first published only 75 years ago. Even though the history of Drosophila research is short, the impact and volume of study on Drosophila has been tremendous during the last decades.
Download or read book Progress and Prospects in Evolutionary Biology written by Jeffrey R. Powell and published by Oxford University Press. This book was released on 1997-09-04 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on drosophila as an especially useful model organism for exploring questions of evolutionary biology in the full range of evolutionary studies: population genetics, ecology, ecological genetics, speciation, phylogenetics, genome evolution, molecular evolution, and development. The author presents an integrated view of evolutionary biology as elucidated in this single organism. Special effort is made to point out holes in our knowledge and areas particularly ripe for new investigation.
Download or read book Extracellular Composite Matrices in Arthropods written by Ephraim Cohen and published by Springer. This book was released on 2016-09-12 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasis is placed on the elaborate cuticular matrices in insects and crustaceans, spider and insect silks, sialomes of phytophagous and blood-feeding arthropods as well as on secretions of male and female accessory glands. Focus is placed largely on insects, due to the extensive body of published research that in part is the result of available whole genome sequences of several model species (in particular Drosophila melanogaster) and accessible ESTs for other species. Such advances have facilitated fundamental insights into genomic, proteomic and molecular biology-based physiology. This new volume contains comprehensive contributions on extracellular composite matrices in arthropods. The building blocks of such matrices are formed in and secreted by single layered epithelial cells into exterior domains where their final assembly takes place.Additionally, the unique mechanical properties of natural biocomposites like chitin/chitosan, the crustacean mineralized exoskeleton, the pliant protein resilin or insect and spider silks, have inspired basic and applied research that yield sophistical biomimetics and structural biocomposite hybrids important for future industrial and biomedical use. In summary, this book provides an invaluable vast source of basic and applied information for a plethora of scientists as well as textbook for graduate and advanced undergraduate students.
Download or read book Drosophila melanogaster written by Farzana Khan Perveen and published by BoD – Books on Demand. This book was released on 2018-02-28 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 12 chapters divided into two sections. Section 1 is "Drosophila - Model for Genetics." It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is "Drosophila - Model for Therapeutics." It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.
Download or read book Biology of Drosophila written by Milislav Demerec and published by CSHL Press. This book was released on 1994 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Drosophila was first published by John Wiley and Sons in 1950. Until its appearance, no central, synthesized source of biological data on Drosophila melanogaster was available, despite the fly's importance to science for three decades. Ten years in the making, it was an immediate success and remained in print for two decades. However, original copies are now very hard to find. This facsimile edition makes available to the fly community once again its most enduring work of reference.
Download or read book Evolutionary Developmental Biology written by Brian K. Hall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although evolutionary developmental biology is a new field, its origins lie in the last century; the search for connections between embryonic development (ontogeny) and evolutionary change (phylogeny) has been a long one. Evolutionary developmental biology is however more than just a fusion of the fields of developmental and evolutionary biology. It forges a unification of genomic, developmental, organismal, population and natural selection approaches to evolutionary change. It is concerned with how developmental processes evolve; how evolution produces novel structures, functions and behaviours; and how development, evolution and ecology are integrated to bring about and stabilize evolutionary change. The previous edition of this title, published in 1992, defined the terms and laid out the field for evolutionary developmental biology. This field is now one of the most active and fast growing within biology and this is reflected in this second edition, which is more than twice the length of the original and brought completely up to date. There are new chapters on major transitions in animal evolution, expanded coverage of comparative embryonic development and the inclusion of recent advances in genetics and molecular biology. The book is divided into eight parts which: place evolutionary developmental biology in the historical context of the search for relationships between development and evolution; detail the historical background leading to evolutionary embryology; explore embryos in development and embryos in evolution; discuss the relationship between embryos, evolution, environment and ecology; discuss the dilemma for homology of the fact that development evolves; deal with the importance of understanding how embryos measure time and place both through development and evolutionarily through heterochrony and heterotrophy; and set out the principles and processes that underlie evolutionary developmental biology. With over one hundred illustrations and photographs, extensive cross-referencing between chapters and boxes for ancillary material, this latest edition will be of immense interest to graduate and advanced undergraduate students in cell, developmental and molecular biology, and in zoology, evolution, ecology and entomology; in fact anyone with an interest in this new and increasingly important and interdisciplinary field which unifies biology.
Download or read book Evolution in the Dark written by Naoyuki Fuse and published by Springer Science & Business Media. This book was released on 2013-09-12 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: How organisms come to possess adaptive traits is a fundamental question for evolutionary biology. Although it is almost impossible to demonstrate evolution in the laboratory, this issue can be approached by using an unusual organism, “Dark-fly”: Drosophila melanogaster kept in complete darkness for 57 years through 1,400 generations, which corresponds to 28,000 years in terms of human generations. Has Dark-fly adapted to an environment of total darkness? If so, what is the molecular nature of the adaptation? In Evolution in the Dark, the remarkable findings from the Dark-fly project performed at Kyoto University are presented. It was found that Dark-fly did not have poor eyesight, but rather exhibited higher phototaxis ability and displayed lengthened bristles on the head that function as tactile receptors. Circadian rhythms were weakened but still retained in Dark-fly. With recent progress in genome science enabling researchers to perform whole genome sequencing for Dark-fly, a large number of mutations were identified including genes encoding a light receptor, olfactory receptors, and enzymes involved in neural development. The Dark-fly project is a simple but very long-term experiment. Combined with advanced techniques in genetics and genomics, it is a valuable tool for understanding the molecular nature of adaptive evolution.
Download or read book Fly Pushing written by Ralph J. Greenspan and published by CSHL Press. This book was released on 2004 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: A second edition of the classic handbook has become a standard in the Drosophila field. This edition is expanded to include topics in which classical genetic strategies have been augmented with new molecular tools. Included are such new techniques as homologous recombination, RNAi, new mapping techniques, and new mosaic marking techniques.
Download or read book The Concept of the Gene in Development and Evolution written by Peter J. Beurton and published by Cambridge University Press. This book was released on 2000-05-29 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biological research in the latter half of the twentieth century have made the story of the gene vastly complicated: the more we learn about genes, the less sure we are of what a gene really is. Knowledge about the structure and functioning of genes abounds, but the gene has also become curiously intangible. This collection of essays renews the question: what are genes? Philosophers, historians and working scientists re-evaluate the question in this volume, treating the gene as a focal point of interdisciplinary and international research. It will be of interest to professionals and students in the philosophy and history of science, genetics and molecular biology.
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Download or read book Ecological and Evolutionary Genetics of Drosophila written by J.S.F. Barker and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecological and evolutionary genetics span many disciplines and virtually all levels of biological investigation, from the genetic information itself to the principles governing the complex organization of living things. The ideas and informa tion generated by ecological and evolutionary genetics provide the substance for strong inferences on the origins, changes and patterns of structural and functional organization in bio logical communi ties. It is the coordination of these ideas and thoughts that will provide the answers to many fundamental questions in biology. There is no doubt that Drosophilids provide strong model systems amenable to experimental manipulation and useful for testing pertinent hypotheses in ecological and evolutionary genetics. The chapters in this volume represent efforts to use Drosophila species for such a purpose. The volume consists of a dedication to William B. Heed, followed by four major sections: Ecological Genetics, Habitat Selection, Biochemical Genetics and Molecular Evolution. Each section is introduced by a short statement, and each chapter has an independent summary. The chapters contain the sub stance of talks given at a joint Australia-US workshop held January 5-10, 1989 at the University of New England, New South Wales, Australia. We are indebted to the Division of International Programs of the National Science Foundation (USA) and to the Science and Technology Collaboration Section of the Department of Industry, Technology and Commerce (Australia) for the provi sion of financial support under the US/Australia Science and Technology Agreement. Many people contributed to the preparation of this volume.
Download or read book Drosophila Melanogaster written by M. Spindler-Barth and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drosophila melanogaster is a species of Diptera, or the order of flies, in the family Drosophilidae. This species is one of the most commonly used model organisms in biology, including studies in genetics, physiology, microbial pathogenesis and life history evolution because they are easy to take care of, breed quickly and lay many eggs. In this book, the authors present current research in the study of drosophila melanogaster including: the gametogenesis, embryonic and post-embryonic development of drosophila melanogaster; the significance of stellate genes in drosophila melanogaster; the evolution of drosophila melanogaster retroviruses and the morphogenesis of drosophila melanogaster macrochaetes.
Download or read book Genetics of Adaptation written by Rodney Mauricio and published by Springer Science & Business Media. This book was released on 2005-07-20 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.
Download or read book Drosophila melanogaster Model for Recent Advances in Genetics and Therapeutics written by Farzana Khan Perveen and published by . This book was released on 2018 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 12 chapters divided into two sections. Section 1 is ""Drosophila - Model for Genetics."" It covers introduction, chromosomal polymorphism, polytene chromosomes, chromosomal inversion, chromosomal evolution, cell cycle regulators in meiosis and nongenetic transgenerational inheritance in Drosophila. It also includes ecological genetics, wild-type strains, morphometric analysis, cytostatics, frequencies of early and late embryonic lethals (EEL and LEL) and mosaic imaginal discs of Drosophila for genetic analysis in biomedical research. Section 2 is ""Drosophila - Model for Therapeutics."" It explains Drosophila as model for human diseases, neurodegeneration, heart-kidney metabolic disorders, cancer, pathophysiology of Parkinson's disease, dopamine, neuroprotective therapeutics, mitochondrial dysfunction and translational research. It also covers Drosophila role in ubiquitin-carboxyl-terminal hydrolase-L1 (UCH-L1) protein, eye development, anti-dUCH antibody, neuropathy target esterase (NTE), organophosphorous compound-induced delayed neuropathy (OPIDN) and hereditary spastic paraplegia (HSP). It also includes substrate specificities, kinetic parameters of recombinant glutathione S-transferases E6 and E7 (DmGSTE6 and DmGSTE7), detoxification and insecticidal resistance and antiviral immunity in Drosophila.
Download or read book Statistical Population Genomics written by Julien Y Dutheil and published by . This book was released on 2020-10-08 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Download or read book Advances in Drosophila Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drosophila Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Drosophila melanogaster. The editors have built Advances in Drosophila Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drosophila melanogaster in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Drosophila Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download or read book Methuselah Flies written by Michael Robertson Rose and published by World Scientific. This book was released on 2004 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methuselah Flies presents a trailblazing project on the biology of aging. It describes research on the first organisms to have their lifespan increased, and their aging slowed, by hereditary manipulation. These organisms are fruit flies from the species Drosophila melanogaster, the great workhorse of genetics. Michael Rose and his colleagues have been able to double the lifespan of these insects, and improved their health in numerous respects as well. The study of these flies with postponed aging is one of the best means we have of understanding, and ultimately achieving, the postponement of aging in humans. As such, the carefully presented detail of this book will be of value to research devoted to the understanding and control of aging.Methuselah Flies: ? is a tightly edited distillation of twenty years of work by many scientists? contains the original publications regarding the longer-lived fruit flies? offers commentaries on each of the topics covered ? new, short essays that put the individual research papers in a wider context? gives full access to the original data ? captures the scientific significance of postponed aging for a wide academic audienc
