Download or read book Advances in Bioinformatics Biostatistics and Omic Sciences written by Luigi Donato and published by Bentham Science Publishers. This book was released on 2020-11-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, and by extension omic sciences – the collective disciplines that are dependent on the use of extensive datasets of biological information – present a challenge of data management for researchers all over the world. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields. Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena. This volume presents reviews on the following topics which give a glimpse of recent advances in the field: - New Integrated Mitochondrial DNA Bioinformatics Pipeline to Improve Quality Assessment of Putative Pathogenic Variants from NGS Experiments - Variant Calling on RNA Sequencing Data: State of Art and Future Perspectives - An innovative Gene Prioritization Pipeline for WES analyses - New Integrated Differential Expression Approach for RNA-Seq Data Analysis - Innovations in Data Visualization for Straightforward Interpretation of Nucleic Acid Omics Outcomes This volume serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.

Download or read book New Developments In Biostatistics And Bioinformatics written by Jianqing Fan and published by World Scientific. This book was released on 2009-04-20 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of recent developments in biostatistics and bioinformatics. Written by active researchers in these emerging areas, it is intended to give graduate students and new researchers an idea of where the frontiers of biostatistics and bioinformatics are as well as a forum to learn common techniques in use, so that they can advance the fields via developing new techniques and new results. Extensive references are provided so that researchers can follow the threads to learn more comprehensively what the literature is and to conduct their own research. In particulars, the book covers three important and rapidly advancing topics in biostatistics: analysis of survival and longitudinal data, statistical methods for epidemiology, and bioinformatics.

Download or read book Advances in Bioinformatics and Its Applications written by Matthew He and published by World Scientific Publishing Company Incorporated. This book was released on 2005 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique volume presents major developments and trends in bioinformatics and its applications, Comprising high-quality scientific research papers and state-of-the-art survey articles, the book has been divided into three main sections: Sequences, Structures, and Functions; Pathways, Biological Networks, and System Biology; and Microarray Data, Medical Informatics, and Applications. These results of these investigations help the practicing biologist in many ways: in identifying unknown connections, in narrowing down possibilities fora search, in suggesting new hypotheses, designing new experiments validating existing models or proposing new ones. It is an essential source of reference for researchers and graduate students in bioinformatics, computer science, mathematics, statistics, and biological sciences based on selected papers from the "The International Conference on Bioinformatics and Its Application" (ICBA), held December 16-19 2004 in Fort Lauderdale, Florida, USA.

Download or read book New Frontiers of Biostatistics and Bioinformatics written by Yichuan Zhao and published by Springer. This book was released on 2018-12-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is comprised of presentations delivered at the 5th Workshop on Biostatistics and Bioinformatics held in Atlanta on May 5-7, 2017. Featuring twenty-two selected papers from the workshop, this book showcases the most current advances in the field, presenting new methods, theories, and case applications at the frontiers of biostatistics, bioinformatics, and interdisciplinary areas. Biostatistics and bioinformatics have been playing a key role in statistics and other scientific research fields in recent years. The goal of the 5th Workshop on Biostatistics and Bioinformatics was to stimulate research, foster interaction among researchers in field, and offer opportunities for learning and facilitating research collaborations in the era of big data. The resulting volume offers timely insights for researchers, students, and industry practitioners.

Download or read book Advances in Bioinformatics and Its Applications written by Matthew He and published by World Scientific. This book was released on 2005-05-03 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique volume presents major developments and trends in bioinformatics and its applications. Comprising high-quality scientific research papers and state-of-the-art survey articles, the book has been divided into five main sections: Microarray Analysis and Regulatory Networks; Machine Learning and Statistical Analysis; Biomolecular Sequence and Structure Analysis; Symmetry in Sequences; and Signal Processing, Image Processing and Visualization. The results of these investigations help the practicing biologist in many ways: in identifying unknown connections, in narrowing down possibilities for a search, in suggesting new hypotheses, designing new experiments, validating existing models or proposing new ones. It is an essential source of reference for researchers and graduate students in bioinformatics, computer science, mathematics, statistics, and biological sciences based on select papers from the “The International Conference on Bioinformatics and Its Application” (ICBA), held December 16–19, 2004 in Fort Lauderdale, Florida, USA. Contents:Microarray Analysis and Regulatory NetworksMachine Learning and Statistical AnalysesBiomolecular Sequence and Structure AnalysisSymmetry in SequencesSignal Processing, Image Processing and Visualization Readership: Researchers and graduate students in bioinformatics, computer science, mathematics and biological sciences. Keywords:Bioinformatics;Mathematical Biology;Genetic Codes;Medical Informatics;Biological Networks;System BiologyKey Features:High quality collection of recent significant advances in bioinformaticsUnique collection of articles on symmetry of genetic code and pattern discoveryWide coverage of bioinformatics applications including computational epidemiologySignificant computational algorithms and statistical analysis of genomic/proteomic data

Download or read book Computational Intelligence Methods for Bioinformatics and Biostatistics written by Enrico Formenti and published by Springer. This book was released on 2014-07-15 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, held in Nice, France in June 2013. The 19 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections on bioinformatics, biostatistics, knowledge based medicine, and data integration and analysis in omic-science.

Download or read book Advances in Statistical Bioinformatics written by Kim-Anh Do and published by Cambridge University Press. This book was released on 2013-06-10 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the integration of high-throughput bioinformatics data from multiple platforms to inform our understanding of the functional consequences of genomic alterations.

Download or read book Handbook of Statistical Bioinformatics written by Henry Horng-Shing Lu and published by Springer Nature. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.

Download or read book New Developments in Biostatistics and Bioinformatics written by Jianqing Fan;Xihong Lin;Jun S. Liu and published by . This book was released on with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of recent developments in biostatistics and bioinformatics. Written by active researchers in these emerging areas, it is intended to give graduate students and new researchers an idea of where the frontiers of biostatistics and bioinformatics are as well as a forum to learn common techniques in use, so that they can advance the fields via developing new techniques and new results. Extensive references are provided so that researchers can follow the threads to learn more comprehensively what the literature is and to conduct their own research. In particulars, the book covers three important and rapidly advancing topics in biostatistics: analysis of survival and longitudinal data, statistical methods for epidemiology, and bioinformatics.

Download or read book Statistical Methods in Bioinformatics written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2005-09-30 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)

Download or read book Bioinformatics written by Rob Botwright and published by Rob Botwright. This book was released on 101-01-01 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the Ultimate Bioinformatics Book Bundle! Dive into the world of bioinformatics with our comprehensive book bundle, featuring four essential volumes that cover everything from foundational concepts to advanced applications. Whether you're a student, researcher, or practitioner in the life sciences, this bundle has something for everyone. Book 1: Bioinformatics Basics Get started with the basics of bioinformatics in this introductory volume. Learn about algorithms, concepts, and principles that form the backbone of bioinformatics research. From sequence analysis to genetic variation, this book lays the groundwork for understanding the fundamental aspects of bioinformatics. Book 2: Coding in Bioinformatics Take your skills to the next level with our coding-focused volume. Explore scripting languages like Python and R, and discover how to apply them to bioinformatics tasks. From data manipulation to machine learning, this book covers a wide range of coding techniques and applications in bioinformatics. Book 3: Exploring Data Science in Bioinformatics Delve into the world of data science and its applications in bioinformatics. Learn about exploratory data analysis, statistical inference, and machine learning techniques tailored specifically for biological data. With practical examples and case studies, this book helps you extract meaningful insights from complex datasets. Book 4: Mastering Biostatistics in Bioinformatics Unlock the power of biostatistics with our advanced methods volume. Explore cutting-edge statistical techniques for analyzing biological data, including survival analysis, meta-analysis, and more. Whether you're conducting experimental studies or analyzing clinical data, this book equips you with the tools you need to draw meaningful conclusions. Why Choose Our Bundle? · Comprehensive Coverage: Covering everything from basic concepts to advanced methods, this bundle provides a complete overview of bioinformatics. · Practical Focus: With hands-on coding exercises and real-world examples, our books emphasize practical skills and applications. · Expert Authors: Authored by experts in the field of bioinformatics, each book offers valuable insights and expertise. · Versatile Learning: Whether you're a beginner or an experienced practitioner, our bundle caters to learners of all levels. Don't miss out on this opportunity to enhance your skills and knowledge in bioinformatics. Order your copy of the Bioinformatics Book Bundle today!

Download or read book Advances in Computers written by Marvin Zelkowitz, Ph.D., MS, BS. and published by Academic Press. This book was released on 2006-12-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of bioinformatics and computational biology arose due to the need to apply techniques from computer science, statistics, informatics, and applied mathematics to solve biological problems. Scientists have been trying to study biology at a molecular level using techniques derived from biochemistry, biophysics, and genetics. Progress has greatly accelerated with the discovery of fast and inexpensive automated DNA sequencing techniques. As the genomes of more and more organisms are sequenced and assembled, scientists are discovering many useful facts by tracing the evolution of organisms by measuring changes in their DNA, rather than through physical characteristics alone. This has led to rapid growth in the related fields of phylogenetics, the study of evolutionary relatedness among various groups of organisms, and comparative genomics, the study of the correspondence between genes and other genomic features in different organisms. Comparing the genomes of organisms has allowed researchers to better understand the features and functions of DNA in individual organisms, as well as provide insights into how organisms evolve over time. The first four chapters of Advances in Computers focus on algorithms for comparing the genomes of different organisms. Possible concrete applications include identifying the basis for genetic diseases and tracking the development and spread of different forms of Avian flu. As researchers begin to better understand the function of DNA, attention has begun shifting towards the actual proteins produced by DNA. The final two chapters explore proteomic techniques for analyzing proteins directly to identify their presence and understand their physical structure. Written by active PhD researchers in computational biology and bioinformatics

Download or read book Computational Intelligence Methods for Bioinformatics and Biostatistics written by Claudia Angelini and published by Springer. This book was released on 2016-07-30 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2015, held in Naples, Italy, in September, 2015. The 21 revised full papers presented were carefully reviewed and selected from 24 submissions. They present problems concerning computational techniques in bioinformatics, systems biology and medical informatics discussing cutting edge methodologies and accelerate life science discoveries, as well as novel challenges with an high impact on molecular biology and translational medicine.

Download or read book Statistical Advances in the Biomedical Sciences written by Atanu Biswas and published by Wiley-Interscience. This book was released on 2007-12-14 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Most Comprehensive and Cutting-Edge Guide to Statistical Applications in Biomedical Research With the increasing use of biotechnology in medical research and the sophisticated advances in computing, it has become essential for practitioners in the biomedical sciences to be fully educated on the role statistics plays in ensuring the accurate analysis of research findings. Statistical Advances in the Biomedical Sciences explores the growing value of statistical knowledge in the management and comprehension of medical research and, more specifically, provides an accessible introduction to the contemporary methodologies used to understand complex problems in the four major areas of modern-day biomedical science: clinical trials, epidemiology, survival analysis, and bioinformatics. Composed of contributions from eminent researchers in the field, this volume discusses the application of statistical techniques to various aspects of modern medical research and illustrates how these methods ultimately prove to be an indispensable part of proper data collection and analysis. A structural uniformity is maintained across all chapters, each beginning with an introduction that discusses general concepts and the biomedical problem under focus and is followed by specific details on the associated methods, algorithms, and applications. In addition, each chapter provides a summary of the main ideas and offers a concluding remarks section that presents novel ideas, approaches, and challenges for future research. Complete with detailed references and insight on the future directions of biomedical research, Statistical Advances in the Biomedical Sciences provides vital statistical guidance to practitioners in the biomedical sciences while also introducing statisticians to new, multidisciplinary frontiers of application. This text is an excellent reference for graduate- and PhD-level courses in various areas of biostatistics and the medical sciences and also serves as a valuable tool for medical researchers, statisticians, public health professionals, and biostatisticians.

Download or read book ADVANCES IN BIOINFORMATICS AND BIG DATA ANALYTICS written by SUJATA. DASH and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Methods in Bioinformatics written by Warren J. Ewens and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)

Download or read book Statistical Analysis of Proteomics Metabolomics and Lipidomics Data Using Mass Spectrometry written by Susmita Datta and published by Springer. This book was released on 2016-12-15 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.