Download or read book Advanced Time Correlated Single Photon Counting Techniques written by Wolfgang Becker and published by Springer Science & Business Media. This book was released on 2005-12-19 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1984 Desmond O’Connor and David Phillips published their comprehensive book „Time-correlated Single Photon Counting“. At that time time-correlated s- gle photon counting, or TCSPC, was used primarily to record fluorescence decay functions of dye solutions in cuvettes. From the beginning, TCSPC was an am- ingly sensitive and accurate technique with excellent time-resolution. However, acquisition times were relatively slow due to the low repetition rate of the light sources and the limited speed of the electronics of the 70s and early 80s. Moreover, TCSPC was intrinsically one-dimensional, i.e. limited to the recording of the wa- form of a periodic light signal. Even with these limitations, it was a wonderful te- nique. More than 20 years have elapsed, and electronics and laser techniques have made impressive progress. The number of transistors on a single chip has approximately doubled every 18 months, resulting in a more than 1,000-fold increase in compl- ity and speed. The repetition rate and power of pulsed light sources have increased by about the same factor.

Download or read book Advanced Photon Counting written by Peter Kapusta and published by Springer. This book was released on 2015-04-23 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on Time-Correlated Single Photon Counting (TCSPC), a powerful tool allowing luminescence lifetime measurements to be made with high temporal resolution, even on single molecules. Combining spectrum and lifetime provides a “fingerprint” for identifying such molecules in the presence of a background. Used together with confocal detection, this permits single-molecule spectroscopy and microscopy in addition to ensemble measurements, opening up an enormous range of hot life science applications such as fluorescence lifetime imaging (FLIM) and measurement of Förster Resonant Energy Transfer (FRET) for the investigation of protein folding and interaction. Several technology-related chapters present both the basics and current state-of-the-art, in particular of TCSPC electronics, photon detectors and lasers. The remaining chapters cover a broad range of applications and methodologies for experiments and data analysis, including the life sciences, defect centers in diamonds, super-resolution microscopy, and optical tomography. The chapters detailing new options arising from the combination of classic TCSPC and fluorescence lifetime with methods based on intensity fluctuation represent a particularly unique highlight.

Download or read book Advanced Photon Counting Techniques X written by Mark A. Itzler and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Time correlated single photon counting written by Desmond O'Connor and published by Academic Press. This book was released on 2012-12-02 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time-correlated Single Photon Counting has been written in the hope that by relating the authors' experiences with a variety of different single photon counting systems, they may provide a useful service to users and potential users of this formidably sensitive technique. Of all the techniques available to obtain information on the rates of depopulation of excited electronic singlet states of molecular species, monitoring of fluorescence provides, in principle, the simplest and most direct measure of concentration. This volume comprises eight chapters, with the first focusing on the time dependence and applications of fluorescence. Succeeding chapters go on to discuss basic principles of the single photon counting lifetime measurement; light sources; photomultipliers; electronics; data analysis; nanosecond time-resolved emission spectroscopy; time dependence of fluorescence anisotropy. This book will be of interest to practitioners in the field of chemistry.

Download or read book Advanced X Ray Radiation Detection written by Krzysztof (Kris) Iniewski and published by Springer Nature. This book was released on 2022-07-04 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers readers an overview of some of the most recent advances in the field of technology for X-ray medical imaging. Coverage includes both technology and applications in SPECT, PET and CT, with an in-depth review of the research topics from leading specialists in the field. Coverage includes conversion of the X-ray signal into analogue/digital value, as well as a review of CMOS chips for X-ray image sensors. Emphasis is on high-Z materials like CdTe, CZT and GaAs, since they offer the best implementation possibilities for direct conversion X-ray detectors. The discussion includes material challenges, detector operation physics and technology and readout integrated circuits required to detect signals processes by high-Z sensors. Authors contrast these emerging technologies with more established ones based on scintillator materials. This book is an excellent reference for people already working in the field as well as for people wishing to enter it.

Download or read book Single Photon Generation and Detection written by and published by Academic Press. This book was released on 2013-11-29 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-photon generation and detection is at the forefront of modern optical physics research. This book is intended to provide a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared. The use of single photons, produced on demand with well-defined quantum properties, offers an unprecedented set of capabilities that are central to the new area of quantum information and are of revolutionary importance in areas that range from the traditional, such as high sensitivity detection for astronomy, remote sensing, and medical diagnostics, to the exotic, such as secretive surveillance and very long communication links for data transmission on interplanetary missions. The goal of this volume is to provide researchers with a comprehensive overview of the technology and techniques that are available to enable them to better design an experimental plan for its intended purpose. The book will be broken into chapters focused specifically on the development and capabilities of the available detectors and sources to allow a comparative understanding to be developed by the reader along with and idea of how the field is progressing and what can be expected in the near future. Along with this technology, we will include chapters devoted to the applications of this technology, which is in fact much of the driver for its development. This is set to become the go-to reference for this field. - Covers all the basic aspects needed to perform single-photon experiments and serves as the first reference to any newcomer who would like to produce an experimental design that incorporates the latest techniques - Provides a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared, thus giving broad background that should enable newcomers to the field to make rapid progress in gaining proficiency - Written by leading experts in the field, among which, the leading Editor is recognized as having laid down the roadmap, thus providing the reader with an authenticated and reliable source

Download or read book Single Photon Generation and Detection written by Sergio Cova and published by Elsevier Inc. Chapters. This book was released on 2013-11-29 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter presents a broad review of the principle, design, fabrication, operation, and performance of single-photon avalanche diodes (SPADs), and provides a comparative basis to assess the relative merits of the wide variety of devices and techniques covered. Particular attention is paid to the design of and operation of both silicon and high-speed-gated InGaAs/InP detection systems, as well as array-based systems.

Download or read book More than Moore Devices and Integration for Semiconductors written by Francesca Iacopi and published by Springer Nature. This book was released on 2023-02-17 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a comprehensive, state-of-the-art reference for miniaturized More-than-Moore systems with a broad range of functionalities that can be added to 3D microsystems, including flexible electronics, metasurfaces and power sources. The book also includes examples of applications for brain-computer interfaces and event-driven imaging systems. Provides a comprehensive, state-of-the-art reference for miniaturized More-than-Moore systems; Covers functionalities to add to 3D microsystems, including flexible electronics, metasurfaces and power sources; Includes current applications, such as brain-computer interfaces, event - driven imaging and edge computing.

Download or read book Issues in Applied Analytical and Imaging Sciences Research 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Applied, Analytical, and Imaging Sciences Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Applied Analysis. The editors have built Issues in Applied, Analytical, and Imaging Sciences Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Applied Analysis in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Applied, Analytical, and Imaging Sciences Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Spectral Photon Counting Computed Tomography written by Katsuyuki Taguchi and published by CRC Press. This book was released on 2020-07-14 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spectral, Photon Counting Computed Tomography is a comprehensive cover of the latest developments in the most prevalent imaging modality (x-ray computed tomography (CT)) in its latest incarnation: Spectral, Dual-Energy, and Photon Counting CT. Disadvantages of the conventional single-energy technique used by CT technology are that different materials cannot be distinguished and that the noise is larger. To address these problems, a novel spectral CT concept has been proposed. Spectral Dual-Energy CT (DE-CT) acquires two sets of spectral data, and Spectral Photon Counting CT (PC-CT) detects energy of x-ray photons to reveal additional material information of objects by using novel energy-sensitive, photon-counting detectors. The K-edge imaging may be a gateway for functional or molecular CT. The book covers detectors and electronics, image reconstruction methods, image quality assessments, a simulation tool, nanoparticle contrast agents, and clinical applications for spectral CT.

Download or read book Handbook for Highly Charged Ion Spectroscopic Research written by Yaming Zou and published by Taylor & Francis. This book was released on 2016-04-19 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: The spectroscopy of highly charged ions plays a key role in numerous areas of physics, from quantum electrodynamics (QED) and parity nonconservation (PNC) testing to fusion and plasma physics to x-ray astronomy. Handbook for Highly Charged Ion Spectroscopic Research brings together many of the techniques and ideas needed to carry out state-of-the-a

Download or read book ETCMOS 2016 Presentation Abstracts written by ETCMOS and published by ETCMOS Services Inc.. This book was released on 2016-06-01 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstracts for presentations at the ETCMOS 2016 conference in Montreal, Canada, May 25 - 27, 2016.

Download or read book Analog Electronics for Radiation Detection written by Renato Turchetta and published by CRC Press. This book was released on 2017-12-19 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analog Electronics for Radiation Detection showcases the latest advances in readout electronics for particle, or radiation, detectors. Featuring chapters written by international experts in their respective fields, this authoritative text: Defines the main design parameters of front-end circuitry developed in microelectronics technologies Explains the basis for the use of complementary metal–oxide semiconductor (CMOS) image sensors for the detection of charged particles and other non-consumer applications Delivers an in-depth review of analog-to-digital converters (ADCs), evaluating the pros and cons of ADCs integrated at the pixel, column, and per-chip levels Describes incremental sigma–delta ADCs, time-to-digital converter (TDC) architectures, and digital pulse-processing techniques complementary to analog processing Examines the fundamental parameters and front-end types associated with silicon photomultipliers used for single visible-light photon detection Discusses pixel sensors with per-pixel TDCs, channel density challenges, and emerging 3D technologies interconnecting detectors and electronics Thus, Analog Electronics for Radiation Detection provides a single source for state-of-the-art information on analog electronics for the readout of radiation detectors.

Download or read book Imaging from Cells to Animals In Vivo written by Margarida Barroso and published by CRC Press. This book was released on 2020-12-03 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging from Cells to Animals In Vivo offers an overview of optical imaging techniques developed over the past two decades to investigate biological processes in live cells and tissues. It comprehensively covers the main imaging approaches used as well as the application of those techniques to biological investigations in preclinical models. Among the areas covered are cell metabolism, receptor-ligand interactions, membrane trafficking, cell signaling, cell migration, cell adhesion, cytoskeleton and other processes using various molecular optical imaging techniques in living organisms, such as mice and zebrafish. Features Brings together biology and advanced optical imaging techniques to provide an overview of progress and modern methods from microscopy to whole body imaging. Fills the need for a comprehensive view of application-driven development and use of new tools to ask new biological questions in the context of a living system. Includes basic chapters on key methods and instrumentation, from fluorescence microscopy and imaging to endoscopy, optical coherence tomography and super-resolution imaging. Discusses approaches at different length scales and biomedical applications to the study of single cell, whole organ, and whole organism behavior. Addresses the impact on discovery, such as cellular function as implicated in human disease and translational medicine, for example in cancer diagnosis.

Download or read book NASA Space Systems Technology Model written by and published by . This book was released on 1985 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Improving the Resolving Power of Ultraviolet to Near Infrared Microwave Kinetic Inductance Detectors written by Nicholas Zobrist and published by Springer Nature. This book was released on 2022-12-12 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis represents a breakthrough in our understanding of the noise processes in Microwave Kinetic Inductance Detectors (MKIDs). While the detection of ultraviolet to near-infrared light is useful for a variety of applications from dark matter searches to biological imaging and astronomy, the performance of these detectors often limits the achievable science. The author’s work explains the limits on spectral resolution broadening, and uses this knowledge to more than double the world record spectral resolution for an MKID suitable for optical and near-IR astrophysics, with emphasis on developing detectors for exoplanet detection. The techniques developed have implication for phonon control in many different devices, particularly in limiting cosmic ray-induced decoherence in superconducting qubits. In addition, this thesis is highly accessible, with a thorough, pedagogical approach that will benefit generations of students in this area.

Download or read book Single Photon Generation and Detection written by J.C. Bienfang and published by Elsevier Inc. Chapters. This book was released on 2013-11-29 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: