Download or read book Advanced Optimization in Image guided Radiation Therapy written by Ki Hwan Choi and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiotherapy is an image-guided intervention, and medical imaging is involved in every key step of the treatment process, ranging from patient staging, simulation, treatment planning, and radiation delivery, to patient follow-up. Image guided-radiation therapy (IGRT) is the most sophisticated method of radiation treatment to address the issue of tumor movement during treatment. IGRT uses advanced imaging technology such as cone-beam CT (CBCT) using on-board imager (OBI) to provide high-resolution, three-dimensional images to pinpoint tumor sites, adjust patient positioning when necessary, and complete a treatment within the standard treatment time slot. Combined with modern technologies in planning and delivering such as intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT), IGRT improves the accuracy of tumor localization while reducing the radiation exposure of healthy tissues. For radiotherapy, repeated CBCT scan of the patient is often required, but excessive radiation exposure is directly related to the risk of polymorphism of genes involved in DNA damage and repair. Hence, we first demonstrate algorithms CBCT for dose reduction. With a low-dose CBCT protocol, the radiation exposure can be mitigated while signal-to-noise ration (SNR) of the measurement is also lowered. It is shown that the high-quality medical image can be reconstructed from noisy CBCT projections by solving an large-scale optimization problem with reasonable preconditioning techniques. In the presence of patient's movement, CBCT projections are highly undersampled, and the precondition in the full-scan case is no longer available. Instead, a first-order method with linearization is adopted for the reconstruction. To further accelerate the convergence speed, we demonstrate a scaling technique in Fourier space. For inverse planning of IGRT, two issues are introduced: beam direction selection and beamlet based optimization. We present an iterative framework suited to modern IMRT/VMAT.
Download or read book Image Guided IMRT written by Thomas Bortfeld and published by Springer Science & Business Media. This book was released on 2006-05-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.
Download or read book Image Processing in Radiation Therapy written by Kristy K. Brock and published by CRC Press. This book was released on 2013-08-06 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Images from CT, MRI, PET, and other medical instrumentation have become central to the radiotherapy process in the past two decades, thus requiring medical physicists, clinicians, dosimetrists, radiation therapists, and trainees to integrate and segment these images efficiently and accurately in a clinical environment. Image Processing in Radiation Therapy presents an up-to-date, detailed treatment of techniques and algorithms for the registration, segmentation, reconstruction, and evaluation of imaging data. It describes how these tools are used in radiation planning, treatment delivery, and outcomes assessment. The book spans deformable registration, segmentation, and image reconstruction and shows how to incorporate these practices in radiation therapy. The first section explores image processing in adaptive radiotherapy, online monitoring and tracking, dose accumulation, and accuracy assessment. The second section describes the mathematical approach to deformable registration. The book presents similarity metrics used for registration techniques, discussing their effectiveness and applicability in radiation therapy. It also evaluates parametric and nonparametric image registration techniques and their applications in radiation therapy processes. The third section assesses the efficiency, robustness, and breadth of application of image segmentation approaches, including atlas-based, level set, and registration-based techniques. The fourth section focuses on advanced imaging techniques for radiotherapy, such as 3D image reconstruction and image registration using a graphics processor unit. With contributions from an international group of renowned authors, this book provides a comprehensive description of image segmentation and registration, in-room imaging, and advanced reconstruction techniques. Through many practical examples, it illustrates the clinical rationale and implementation of the techniques.
Download or read book Adaptive Radiation Therapy written by X. Allen Li and published by CRC Press. This book was released on 2011-01-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern medical imaging and radiation therapy technologies are so complex and computer driven that it is difficult for physicians and technologists to know exactly what is happening at the point-of-care. Medical physicists responsible for filling this gap in knowledge must stay abreast of the latest advances at the intersection of medical imaging an
Download or read book Principles and Practice of Image Guided Radiation Therapy of Lung Cancer written by Jing Cai and published by CRC Press. This book was released on 2017-09-18 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive overview on the use of image-guided radiation therapy (IGRT) in the treatment of lung cancer, covering step-by-step guidelines for clinical implementations, fundamental principles and key technical advances. It covers benefits and limitations of techniques as well as quality and safety issues related to IGRT practice. Addresses imaging simulation, treatment planning, verification, and delivery Discusses important quality assurance issues Describes current methods using specialized machines and technologies Jing Cai, PhD, is an Associate Professor of Radiation Oncology at Duke University Medical Center. Joe Y. Chang, MD, PhD, is Professor in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center in Houston. Fang-Fang Yin, PhD, is Chief of the Division of Radiation Physics, Professor of Radiation Oncology, and Director of the Medical Physics program at Duke University.
Download or read book Image Guided and Adaptive Radiation Therapy written by Robert D. Timmerman and published by Lippincott Williams & Wilkins. This book was released on 2012-10-09 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed, state-of-the-art information and guidelines on the latest developments, innovations, and clinical procedures in image-guided and adaptive radiation therapy. The first section discusses key methodological and technological issues in image-guided and adaptive radiation therapy, including use of implanted fiducial markers, management of respiratory motion, image-guided stereotactic radiosurgery and stereotactic body radiation therapy, three-dimensional conformal brachytherapy, target definition and localization, and PET/CT and biologically conformal radiation therapy. The second section provides practical clinical information on image-guided adaptive radiation therapy for cancers at all common anatomic sites and for pediatric cancers. The third section offers practical guidelines for establishing an effective image-guided adaptive radiation therapy program.
Download or read book Image guided Radiation Therapy written by Arno J. Mundt and published by PMPH-USA. This book was released on 2010-12-31 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image Guided Radiation Therapy (IGRT) is a true revolution in the field of radiation oncology. IGRT provides the unprecedented means of conforming does to the shape of the target tissues in 3-dimensions reducing the risk of complications thereby improving the quality of life of irradiated patients. Moreover, IGRT provides the means to deliver higher than conventional doses thus improving the chance of cure in these patients. Despite its established benefits, several barriers exist to the widespread clinical implementation of IGRT. In the past, great concerns existed regarding the large capital outlay needed for both software and hardware. This barrier is less relevant today given the increased reimbursements possible with IGRT. Today, the most significant barrier is education. IGRT is a fundamentally new approach to both treatment planning and delivery. Adoption of the IGRT approach entails new ways of thinking in regard to patient selection, treatment planning and quality assurance measures. Unfortunately, apart from a few University-based short courses, limited resources are available for the physician and physicist interested in learning IGRT.
Download or read book Image Based Computer Assisted Radiation Therapy written by Hidetaka Arimura and published by Springer. This book was released on 2017-01-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the state-of-the-art computational intelligence research and technologies in computer-assisted radiation therapy based on image engineering. It also traces major technical advancements and research findings in the field of image-based computer-assisted radiation therapy. In high-precision radiation therapies, novel approaches in image engineering including computer graphics, image processing, pattern recognition, and computational anatomy play important roles in improving the accuracy of radiation therapy and assisting decision making by radiation oncology professionals, such as radiation oncologists, radiation technologists, and medical physicists, in each phase of radiation therapy. All the topics presented in this book broaden understanding of the modern medical technologies and systems for image-based computer-assisted radiation therapy. Therefore this volume will greatly benefit not only radiation oncologists and radiologists but also radiation technologists, professors in medical physics or engineering, and engineers involved in the development of products to utilize this advanced therapy.
Download or read book Image Guided Radiation Therapy written by J. Daniel Bourland and published by Taylor & Francis. This book was released on 2012-02-22 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image-Guided Radiation Therapy presents key image-guided radiation treatment (IGRT) technologies for external beam radiotherapy. The book explores the decades-long technological developments that have occurred in the realm of image-guided conformal, customized radiation treatment. Expert authors, all of whom have actively participated in the develo
Download or read book Image Guided High Precision Radiotherapy written by Esther G. C. Troost and published by Springer Nature. This book was released on 2022-10-11 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book equips readers with detailed knowledge on the current status of image-guided radiotherapy with photons and particles and highlights issues that need to be addressed in order to further improve treatment outcomes. The opening chapters cover clinical and technical aspects of target volume definition using anatomic (computed tomography and magnetic resonance imaging; MRI) as well as functional (MRI and positron emission tomography) imaging. Up-to-date information is then provided on the full range of image-guided high-precision radiotherapy techniques, including IMRT/VMAT, stereotactic body radiation therapy, MR-guided linear accelerators, MR-guided brachytherapy, and particle therapy. The role of ultrasonography in image-guided radiotherapy is discussed, as are the available means for target volume demarcation and stabilization and adaptive radiation therapy. Finally, outcome evaluation is explored in depth, with a particular focus on the role of multimodality imaging in predicting tumor control and normal tissue toxicity. The authors are experts in different specialties and the book will be of high value for radiation oncologists, medical physicists, radiologists, nuclear medicine physicians, and radiation technicians.
Download or read book Advances in Radiation Oncology written by Jeffrey Y.C. Wong and published by Springer. This book was released on 2017-04-20 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.
Download or read book Optimization of Image guided Radiotherapy IGRT for Lung Cancer written by and published by . This book was released on 2010 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Intensity Modulated Radiation Therapy written by Yasumasa Nishimura and published by Springer. This book was released on 2015-04-16 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist.
Download or read book Adaptive Motion Compensation in Radiotherapy written by Martin J. Murphy and published by CRC Press. This book was released on 2011-12-14 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: External-beam radiotherapy has long been challenged by the simple fact that patients can (and do) move during the delivery of radiation. Recent advances in imaging and beam delivery technologies have made the solution—adapting delivery to natural movement—a practical reality. Adaptive Motion Compensation in Radiotherapy provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. This authoritative book discusses: Each of the contributing elements of a motion-adaptive system, including target detection and tracking, beam adaptation, and patient realignment Treatment planning issues that arise when the patient and internal target are mobile Integrated motion-adaptive systems in clinical use or at advanced stages of development System control functions essential to any therapy device operating in a near-autonomous manner with limited human interaction Necessary motion-detection methodology, repositioning techniques, and approaches to interpreting and responding to target movement data in real time Medical therapy with external beams of radiation began as a two-dimensional technology in a three-dimensional world. However, in all but a limited number of scenarios, movement introduces the fourth dimension of time to the treatment problem. Motion-adaptive radiation therapy represents a truly four-dimensional solution to an inherently four-dimensional problem. From these chapters, readers will gain not only an understanding of the technical aspects and capabilities of motion adaptation but also practical clinical insights into planning and carrying out various types of motion-adaptive radiotherapy treatment.
Download or read book Intensity Modulated Radiation Therapy written by S. Webb and published by CRC Press. This book was released on 2015-05-06 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical conformal radiotherapy is the holy grail of radiation treatment and is now becoming a reality through the combined efforts of physical scientists and engineers, who have improved the physical basis of radiotherapy, and the interest and concern of imaginative radiotherapists and radiographers. Intensity-Modulated Radiation Therapy de
Download or read book Radiation Therapy Techniques for Gynecological Cancers written by Kevin Albuquerque and published by Springer. This book was released on 2019-02-19 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide to the use of modern radiation therapy techniques in women with gynecological cancers. Step-by-step instruction is provided on simulation, contouring, and treatment planning and delivery for cancers of the cervix, endometrium, vagina, and vulva. Beyond external beam radiation delivery, full details are presented on three-dimensional brachytherapy at all sites for which it is applicable. Moreover, in-depth guidance is offered on the various advanced techniques of radiation delivery, including intensity-modulated radiation therapy, image guidance for external beam and brachytherapy, and stereotactic body radiotherapy. Radiation therapy is a critical component of the multidisciplinary management of gynecological tumors. With modern technology, both external beam radiation and brachytherapy can be delivered in a highly conformal way. This requires precise contouring and accurate planning techniques. In clearly describing the indications for and the delivery of quality radiation therapy for gynecological tumors, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and radiotherapy residents.
Download or read book Surface Guided Radiation Therapy written by Jeremy David Page Hoisak and published by CRC Press. This book was released on 2020-02-13 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Guided Radiation Therapy provides a comprehensive overview of optical surface image guidance systems for radiation therapy. It serves as an introductory teaching resource for students and trainees, and a valuable reference for medical physicists, physicians, radiation therapists, and administrators who wish to incorporate surface guided radiation therapy (SGRT) into their clinical practice. This is the first book dedicated to the principles and practice of SGRT, featuring: Chapters authored by an internationally represented list of physicists, radiation oncologists and therapists, edited by pioneers and experts in SGRT Covering the evolution of localization systems and their role in quality and safety, current SGRT systems, practical guides to commissioning and quality assurance, clinical applications by anatomic site, and emerging topics including skin mark-less setups. Several dedicated chapters on SGRT for intracranial radiosurgery and breast, covering technical aspects, risk assessment and outcomes. Jeremy Hoisak, PhD, DABR is an Assistant Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Hoisak’s clinical expertise includes radiosurgery and respiratory motion management. Adam Paxton, PhD, DABR is an Assistant Professor in the Department of Radiation Oncology at the University of Utah. Dr. Paxton’s clinical expertise includes patient safety, motion management, radiosurgery, and proton therapy. Benjamin Waghorn, PhD, DABR is the Director of Clinical Physics at Vision RT. Dr. Waghorn’s research interests include intensity modulated radiation therapy, motion management, and surface image guidance systems. Todd Pawlicki, PhD, DABR, FAAPM, FASTRO, is Professor and Vice-Chair for Medical Physics in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Pawlicki has published extensively on quality and safety in radiation therapy. He has served on the Board of Directors for the American Society for Radiology Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM).
