Download or read book Adhesives in Biomedical Applications written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2023-10-17 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: ADHESIVES IN BIOMEDICAL APPLICATIONS Uniquely provides up-to-date and comprehensive information on adhesives in biomedical applications in an easily accessible form. Adhesives are gaining popularity in many and varied biomedical applications as they are being used as a replacement for sutures and staples, which have the disadvantages such as scarring, infection, keloid formation, poor skin healing, or hernia in the case of abdominal sutures. On the other hand, adhesives dramatically reduce healthcare costs, significantly reduce time spent in surgery, curb the risks of bleeding, and are generally easy to use. Adhesives also find their use in diagnostic imaging, various biomedical devices, dental adhesives, dermal adhesives, etc. Adhesives in Biomedical Applications contains eleven chapters and is divided into two parts: Part 1: General Topics; and Part 2: Specific Adhesives, Characteristics, and Applications. Topics covered include: historical developments of various adhesives for biomedical applications; global industry development and analysis of adhesives for biomedical applications; biomedical adhesives; bioadhesion: fundamentals and mechanisms; fibrin glue; herbal bioactives-based mucoadhesive drug delivery systems; adhesive hydrogels; adhesives in dermal patches; medical adhesives from extracted mussel adhesive proteins; dental adhesives; and the role of adhesive-based systems for diagnostic imaging and theranostic applications. Audience The book will be used by adhesionists, adhesive technologists, polymer scientists, materials scientists, as well as those involved with biomedical devices and bioimplants such as medical doctors, surgeons, cosmetologists, as well as engineers in the pharmaceutical industry.

Download or read book Green Adhesives written by Inamuddin and published by John Wiley & Sons. This book was released on 2020-06-03 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Adhesives: Preparation, Properties and Applications deals with the fabrication methods, characterization, and applications of green adhesives. It also includes the collective properties of waterborne, bio, and wound-healing green adhesives. Exclusive attention is devoted to discussing the applications of green adhesives in biomedical coatings, food, and industrial applications.

Download or read book Biological and Biomimetic Adhesives written by Romana Santos and published by Royal Society of Chemistry. This book was released on 2013 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publication of the Cost Action Group TD0906. A volume based on the proceedings of the 1st International Conference on Biological and Biomimetic Adhesives that was held at the University of Lisbon, Portugal 9-11 May 2012.

Download or read book Adhesive Materials for Biomedical Applications written by Andrea J Vernengo and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, polymeric bioadhesives have become known as promising alternatives to sutures, staples, and wires. Traditional wound closure techniques are time-consuming to apply and cause additional tissue damage. In instances of large-scale hemorrhage or minimally invasive laparoscopic surgery, sutures are impractical to apply. Alternatively, newly developed bioadhesives are polymers that can be dripped or sprayed over superficial or internal injuries, solidifying in situ to form a seal that apposes tissue or arrests bleeding over large areas. This review will outline the main categories of polymers that have been investigated for these applications. The chemistry, mechanisms of adhesion, and advantages and limitations of each category will be described. In addition, needs for next-generation adhesives in tissue engineering will be discussed. For the repair of certain load-bearing areas of the body, such as cartilage and the intervertebral disc, scaffold adhesion is necessary for anchoring the scaffold in place and providing adequate transmission of forces. Researchers continue developing new formulations that exhibit improved biocompatibility, strength, elasticity, and degradability. These advances promise to improve clinical outcomes by enhancing bleeding control and wound healing. In the long term, bioadhesives will play an important role in making orthopedic and musculoskeletal tissue engineering clinically feasible.

Download or read book Adhesives written by Anna Rudawska and published by BoD – Books on Demand. This book was released on 2016-11-23 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents some information regarding adhesives which have applications in industry, medicine and dentistry. The book is divided into two parts: "Adhesives Applications in Medicine and Dentistry" and "Properties of Adhesive." The aim of such a presentation is to present the usage in very different aspects of application of the adhesives and present specific properties of adhesives. Adhesives' advantageous properties and relatively uncomplicated processing methods contribute to their increasing application and their growing popularity in the industry, medicine and other branches. Some adhesives represent properties superior to those of most adhesive materials, due to their excellent adhesion and chemical resistance. A wide variety of adhesives' considerable flexibility in modification of properties of adhesives allows adjusting the composition to particular applications.

Download or read book Biological Adhesives written by Andrew M. Smith and published by Springer Science & Business Media. This book was released on 2007-01-12 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals. As we learn more about their molecular and mechanical properties we begin to understand why they adhere so well and with this comes broad applications in areas such as medicine, dentistry, and biotechnology.

Download or read book Adhesive Hydrogels Design Fabrication and Bio applications written by Qihui Zhou and published by Frontiers Media SA. This book was released on 2023-10-23 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, adhesive hydrogels have gained increasing attention as emerging biomedical materials due to high demand for fundamental research and practical biomedical applications, because tissue adhesiveness enables integration with surrounding tissues. Recently, adhesive hydrogels have been used in many areas of biomedicine, such as implant scaffolds in tissue engineering, mucosal adhesives to extend the administration site time, and bio-adhesives in place of seam needles to reduce infection. The tissue-adhesion ability of hydrogels are governed by adhesion and cohesion. Adhesion is the bond generated between hydrogels and tissue surfaces. Cohesion is the internal strength that holds the hydrogel network together and determines the mechanical strength of the materials. Adhesive hydrogels require sufficient cohesion to allow the typical extrusion, contraction, and expansion of tissues. In addition, high adhesion and cohesion prevent hydrogels from detaching during hemostasis or occlusion or from being damaged by fast-flowing fluids (such as blood). Despite impressive progress in adhesive hydrogels for biomedical applications, there are a number of unanswered questions in this line of research. For example, how can smart adhesive hydrogels be developed for specific biomedical purposes, such as reversible adhesion? How to control the toxicity of adhesive hydrogel in the body? How can wet adhesion be achieved, especially in the moist environment of the mouth and stomach? How to prevent adhesion with other normal tissues? How to provide the hydrogel with multifunctions, such as self-healing and strong mechanical strength. We welcome researchers to submit articles (original research, reviews, mini-reviews, and perspective articles). Possible topics include, but are not limited to: • Design and preparation of bioadaptability adhesive hydrogel • Adhesive hydrogel for anti-bacteria/biofilm/infection • Adhesive hydrogel for fast hemostasis • Adhesive hydrogel for tissue repair and regeneration • The underlying mechanisms and interactions between adhesive hydrogel and cell/tissue/organ • Toxicology evaluation on adhesive hydrogel • Application of adhesive hydrogel in wearable electronic devices

Download or read book Adhesion in Pharmaceutical Biomedical and Dental Fields written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2017-06-15 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only book to cover adhesion in pharmaceutical, biomedical and dental fields The phenomenon of adhesion is of cardinal importance in the pharmaceutical, biomedical and dental fields. A few eclectic examples will suffice to underscore the importance/relevance of adhesion in these three areas. For example, the adhesion between powdered solids is of crucial importance in tablet manufacture. The interaction between biodevices (e.g., stents, bio-implants) and body environment dictates the performance of such devices, and there is burgeoning research activity in modifying the surfaces of such implements to render them compatible with bodily components. In the field of dentistry, the modern trend is to shift from retaining of restorative materials by mechanical interlocking to adhesive bonding. The book contains 15 chapters written by internationally-renowned subject matter experts and is divided into four parts: Part 1: General Topics; Part 2: Adhesion in Pharmaceutical Field; Part 3: Adhesion in Biomedical Field; and Part 4: Adhesion in Dental Field. The topics covered include: Theories or mechanisms of adhesion; wettability of powders; role of surface free energy in tablet strength and powder flow behavior; mucoadhesive polymers for drug delivery systems; transdermal patches; skin adhesion in long-wear cosmetics; factors affecting microbial adhesion; biofouling and ways to mitigate it; adhesion of coatings on surgical tools and bio-implants; adhesion in fabrication of microarrays in clinical diagnostics; antibacterial polymers for dental adhesives and composites; evolution of dental adhesives; and testing of dental adhesive joints.

Download or read book Progress in Adhesion and Adhesives Volume 6 written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2021-08-24 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the voluminous research being published, it is difficult, if not impossible, to stay abreast of current developments in a given area. The review articles in this book consolidate information to provide an alternative way to follow the latest research activity and developments in adhesion science and adhesives. With the ever-increasing amount of research being published, it is a Herculean task to be fully conversant with the latest research developments in any field, and the arena of adhesion and adhesives is no exception. Thus, topical review articles provide an alternate and very efficient way to stay abreast of the state-of-the-art in many subjects representing the field of adhesion science and adhesives. The 19 chapters in this Volume 6 follow the same order as the review articles originally published in RAA in the year 2020 and up to June 2021. The subjects of these 19 chapters fall in the following areas: Adhesives and adhesive joints Contact angle Reinforced polymer composites Bioadhesives Icephobic coatings Adhesives based on natural resources Polymer surface modification Superhydrophobic surfaces The topics covered include: hot-melt adhesives; adhesively-bonded spar-wingskin joints; contact angle hysteresis; fiber/matrix adhesion in reinforced thermoplastic composites; bioadhesives in biomedical applications; mucoadhesive pellets for drug delivery applications; bio-inspired icephobic coatings; wood adhesives based on natural resources; adhesion in biocomposites; vacuum UV surface photo-oxidation of polymers and other materials; vitrimers and their relevance to adhesives; superhydrophobic surfaces by microtexturing; structural acrylic adhesives; mechanically durable water-repellent surfaces; mussel-inspired underwater adhesives; and cold atmospheric pressure plasma technology for modifying polymers. Audience This book will be valuable and useful to researchers and technologists in materials science, nanotechnology, physics, surface and colloid chemistry in multiple disciplines in academia, industry, various research institutes and other organizations.

Download or read book Progress in Adhesion and Adhesives Volume 7 written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2023-12-07 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book contains eight commissioned chapters and cover topics including stress distribution and design analysis of adhesively bonded tubular composite joints; durability of structural adhesive joints; mechanical surface treatment of adherends for adhesive bonding; surface modification of polymer materials by excimer UV light; corona discharge treatment of materials to enhance adhesion; adhesion activation of aramid fibers; dual-cured hydrogels for bioadhesives and biomedical applications; and non-adhesive SLIPS-like surfaces.

Download or read book Antimicrobial Materials for Biomedical Applications written by Abraham J Domb and published by Royal Society of Chemistry. This book was released on 2019-08-02 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the need to combat emerging infectious diseases, research around antimicrobial biomaterials and their applications is booming. This book provides the field with a much-needed fundamental overview of the science, addressing the chemistry of a broad range of biomaterial types, and their applications in the biomedical industry. Materials covered include polymers, from those with inherent antimicrobial activity to those that release antimicrobial agents, antimicrobial ceramics and inorganic compounds, such as metal based antimicrobial additives, and the developing field of biomimetic materials, are discussed. Surfaces, coatings and adhesives are covered, whilst the applications of these antimicrobial materials in biomedical applications, from catheters to orthopaedics, dentistry to ophthalmology, are explored. Edited by international leaders and with contributions from the best in the field, this book is the go-to resource for graduates and researchers in biomaterials science, biomedical engineering, chemical engineering, and materials and polymer chemistry.

Download or read book Lignin based Materials for Biomedical Applications written by Patrícia Figueiredo and published by Elsevier. This book was released on 2021-07-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lignin-based Materials for Biomedical Applications: Preparation, Characterization, and Implementation explores the emerging area of lignin-based materials as a platform for advanced biomedical applications, guiding the reader from source through to implementation. The first part of the book introduces the basics of lignin, including extraction methods, chemical modifications, structure and composition, and properties that make lignin suitable for biomedical applications. In addition, structural characterization techniques are described in detail. The next chapters focus on the preparation of lignin-based materials for biomedical applications, presenting methodologies for lignin-based nanoparticles, hydrogels, aerogels, and nanofibers, and providing in-depth coverage of lignin-based materials with specific properties—including antioxidant properties, UV absorbing capability, antimicrobial properties, and colloidal particles with tailored properties—and applications, such as drug and gene delivery, and tissue engineering. Finally, future perspectives and possible new applications are considered. This is an essential reference for all those with an interest in lignin-based materials and their biomedical applications, including researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, and biomedical engineering, as well as industrial R&D and scientists involved with bio-based polymers, specifically for biomedical applications. Unlocks the potential of lignin-based materials with advanced properties for cutting-edge applications in areas such as drug delivery, gene delivery and tissue engineering Presents state-of-the-art methodologies used in the development of lignin-based nanoparticles, hydrogels, aerogels and nanofibers Explains the fundamentals of lignin, including structure and composition, extraction and isolation methods, types and properties, chemical modifications, and characterization techniques

Download or read book Bio inspired Structured Adhesives written by Lars Heepe and published by Springer. This book was released on 2017-07-21 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the adhesion, friction and contact mechanics of living organisms. Further, it presents the remarkable adhesive abilities of the living organisms which inspired the design of novel micro- and nanostructured adhesives that can be used in various applications, such as climbing robots, reusable tapes, and biomedical bandages. The technologies for both the synthesis and construction of bio-inspired adhesive micro- and nanostructures, as well as their performance, are discussed in detail. Representatives of several animal groups, such as insects, spiders, tree frogs, and lizards, are able to walk on (and therefore attach to) tilted, vertical surfaces, and even ceilings in different environments. Studies have demonstrated that their highly specialized micro- and nanostructures, in combination with particular surface chemistries, are responsible for this impressive and reversible adhesion. These structures can maximize the formation of large effective contact areas on surfaces of varying roughness and chemical composition under different environmental conditions.

Download or read book ENGINEERING ELECTROCONDUCTIVE AND ADHESIVE HYRDOGELS FOR BIOMEDICAL APPLICATIONS written by Brian Wayne Walker and published by . This book was released on 2020 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioadhesives, such as tissue sealants, hemostatic agents, and tissue sealants have gained increasing popularity for addressing wound management for traumatic and surgical injuries. This new generation of adhesive demonstrates significant advantages over traditional suturing and stapling techniques that can lead to infection, leakage of bodily fluid and gas, as well as secondary damage to tissues. Bioadhesives can be most broadly classified based on internal or external administration. While bioadhesives designed for external use are most widely used for topical application, such as wound closure, internal bioadhesives are surgically implanted and, therefore, require biocompatibility and strong adhesive ability to wet tissues. Further, hydrogel-based bioadhesives may be designed with nanoparticles or biopolymers that impart specific functionality, such as conductive or hemostatic properties. Scaffolds designed with conductive biomaterials have been extensively investigated in the field of tissue engineering based on their ability to support the function of excitable cell types, such as cardiomyocytes and neurons. Bioadhesives have also been designed to promote hemostasis for applications such as surgical sealants. In first two sections of this project, we aimed to develop conductive bioadhesives for cardiac tissue repair by combining highly biocompatible gelatin methacryloyl (GelMA), with an electrically conductive choline-based bio ionic liquid (Bio-IL). Here, we chemically modified gelatin to form photocrosslinkable hydrogels in the presence of visible or UV light, depending on the photoinitiator used. Conductive hydrogels were fabricated with varying concentrations of GelMA and Bio-IL, which resulted in scaffolds with high biocompatibility, as well as tunable electrical conductivity, and mechanical strength. We then demonstrated the ability of Bio-IL conjugated hydrogels to transduce physicochemical stimuli and modulate the growth of primary CMs in both 2D and 3D cultures in vitro. In addition, we demonstrated that the engineered hydrogels were highly biodegradable and biocompatible in vitro, and that they did not elicit inflammatory responses when implanted in vivo. Our following project investigated the development of cardiopatches using electrospun GelMA conjugated with Bio-IL. The resulting cardiopatches demonstrated tunable conductive and mechanical properties by optimizing the concentration of GelMA and Bio-IL used during synthesis. GelMA/Bio-IL cardiopatches exhibited excellent adhesiveness to cardiac tissues, and biocompatibility both in vitro and in vivo. CMs and CFs seeded on the surface of cardiopatches demonstrated excellent cell attachment and proliferation, and the scaffold supported the expression of gap junction proteins indicating the cells ability to function synchronously. Taken together, these conductive bioadhesives demonstrated excellent potential to be readily tailored to cardiac tissue regenerative therapies. Lastly, our group developed a hemostatic surgical sealant with robust mechanical properties based on the biopolymers GelMA and elastin-like polypeptide (ELP). These adhesive hydrogels were rendered hemostatic by the incorporation of the synthetic clay Laponite (LA) and were rapidly photocrosslinked in the presence of UV radiation using the photoinitiator Irgacure 2959. We demonstrated the highly tunable mechanical and adhesive properties of these nanocomposite hydrogels by varying the concentrations of GelMA and ELP. Likewise, we demonstrated the excellent hemostatic performance of these scaffolds both in vitro and in vivo by varying the concentration of LA. Our nanocomposite GelMA/ELP/LA hydrogels also showed remarkable biocompatibility both in vitro and in vivo and did not elicit an inflammatory response when implanted subcutaneously.

Download or read book Advances in Biomaterials for Biomedical Applications written by Anuj Tripathi and published by Springer. This book was released on 2017-01-24 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Download or read book Handbook of Adhesion Technology written by Lucas F. M. da Silva and published by Springer. This book was released on 2021-01-14 with total page 1543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adhesives have been used for thousands of years, but until 100 years ago, the vast majority was from natural products such as bones, skins, fish, milk, and plants. Since about 1900, adhesives based on synthetic polymers have been introduced, and today, there are many industrial uses of adhesives and sealants. It is difficult to imagine a product—in the home, in industry, in transportation, or anywhere else for that matter—that does not use adhesives or sealants in some manner. The Handbook of Adhesion Technology is intended to be the definitive reference in the field of adhesion. Essential information is provided for all those concerned with the adhesion phenomenon. Adhesion is a phenomenon of interest in diverse scientific disciplines and of importance in a wide range of technologies. Therefore, this handbook includes the background science (physics, chemistry and materials science), engineering aspects of adhesion and industry specific applications. It is arranged in a user-friendly format with ten main sections: theory of adhesion, surface treatments, adhesive and sealant materials, testing of adhesive properties, joint design, durability, manufacture, quality control, applications and emerging areas. Each section contains about five chapters written by internationally renowned authors who are authorities in their fields. This book is intended to be a reference for people needing a quick, but authoritative, description of topics in the field of adhesion and the practical use of adhesives and sealants. Scientists and engineers of many different backgrounds who need to have an understanding of various aspects of adhesion technology will find it highly valuable. These will include those working in research or design, as well as others involved with marketing services. Graduate students in materials, processes and manufacturing will also want to consult it.

Download or read book Surgical Adhesives Sealants written by David H. Sierra and published by CRC Press. This book was released on 2020-03-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgical tissue adhesives are an ancient idea, going back to the beginnings of recorded history. The concept of adhering, rather than suturing, packing, or stapling planes of tissue is attractive, in that it is fast-acting and assures complete closure. Numerous technologies have been tried; some with limited success, others outright failures. In short, the perfect adhesive does not exist. Limitations occur in a number of areas: strength, toxicity, degradation, and safety. It is also important to keep in mind that "one size fits all" does not apply to adhesives in surgical applications any more than it does in day-to-day application. As one would not use paper glue to seal a bathtub, one would presumably not apply an adhesive onto tendons, which is suitable for sealing corneas. The properties required of an adhesive for each indication are quite different. Over the last twenty-five years, advances have been made in a wide range of technologies targeting some embodiment of a practical and safe adhesive. Foremost and successful among these are cyanoacrylates, marine adhesive proteins, and fibrin-based sealants. Another promising adhesive technology is laser solders, a mixture of polypeptides and proteoglycans, which integrates with the repair site when laser energy is applied. In light of these advances in the field, the Symposium for Surgical Tissue Adhesives was organized and held at the Atlanta Hyatt from October 8-10, 1993. The goal was to bring together these far-flung technologies in a comprehensive and cohesive manner. Presentations by investigators from around the world described the history of adhesives in medicine, current technologies, laboratory characterizations, and application developments, as well as regulatory aspects and clinical applications. We felt that as many viewpoints as possible, however conflicting, were important to present in order to give the most complete picture of the state of the art of surgical adhesives.