Download or read book Acute Respiratory Tract Toxicity of the Trichothecene Mycotoxin T 2 Toxin written by and published by . This book was released on 1987 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: The systemic toxicology of trichothecene mycotoxins in a variety of laboratory and farm animals is well documented. Toxicity reports following respiratory exposure, however, are mostly anecdotal. For instance, Ismailson first called attention to toxicosis secondary to mold spore inhalation in a binder twine factory. More recently, Forgacs described symptoms of a severe pharyngitis, or burning sensation in the nose accompanied by bloody nasal discharge and a moderate to severe cough in workers that developed stachybotryotoxicosis after inhaling dusts from Stachybotrys-contaminated straw. Ueno reported 100% lethality of five mice 5 days after a 160-minute exposure to 140 ppb of T-2 mycotoxin. However, no information on aerosol generation or aersol characterization was given, and only very limited information on exposure conditions was presented. A report issued in 1983 by the Committee on Protection Against Trichothecene Mycotoxins noted that there was a lack of information on inhalation exposure to trichothecene toxins and recommended that this route of exposure be studied. Keywords: Phytotoxins.
Download or read book Acute Inhalation Toxicity of T 2 Mycotoxin in Mice and Guinea Pigs written by and published by . This book was released on 1988 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this study a concentration-response was determined for rats and guinea pigs systematically exposed to an aerosol of T-2 toxin. The LC50 for a 10 min exposure to T-2 toxin aerosol was 0.020 mg T-2/liter air for rats and 0.21 mg T-2/liter air for guinea pigs. Data from total T-2 deposition in rats and guinea pigs exposed to their respective LC50 aerosol concentration gave an LD50 of 0.046 mg T-2/kg body weight for the rat and 0.50 mg T-2/kg body weight for the guinea pig. These data show that inhaled T-2 toxin is at least 10 times more toxic to the rat (0.046 mg T-2/kg body weight inhaled vs 1.0 mg T-2/kg body weight systemic) and twice as toxic to the guinea pig (0.5 mg T-2/kg body weight inhaled vs. 1-2 mg T-2 kg body weight systemic) than systemically administered T-2 toxin. Guinea pigs exposed to T-2 aerosols with varied times and aerosol concentration showed that when given the same received dose over a shorter interval of time, T-2 was more toxic, Histopathology of major organs in both the rat and guinea pig after respiratory exposure to T-2 toxin was similar to that after systemic administration of T-2 toxin. Histopathology of the respiratory tract after T-2 aerosol exposure was minimal and could not account for the increased toxicity of inhaled T-2 toxin. Keywords: Phytotoxins.
Download or read book Damp Indoor Spaces and Health written by Institute of Medicine and published by National Academies Press. This book was released on 2004-10-01 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost all homes, apartments, and commercial buildings will experience leaks, flooding, or other forms of excessive indoor dampness at some point. Not only is excessive dampness a health problem by itself, it also contributes to several other potentially problematic types of situations. Molds and other microbial agents favor damp indoor environments, and excess moisture may initiate the release of chemical emissions from damaged building materials and furnishings. This new book from the Institute of Medicine examines the health impact of exposures resulting from damp indoor environments and offers recommendations for public health interventions. Damp Indoor Spaces and Health covers a broad range of topics. The book not only examines the relationship between damp or moldy indoor environments and adverse health outcomes but also discusses how and where buildings get wet, how dampness influences microbial growth and chemical emissions, ways to prevent and remediate dampness, and elements of a public health response to the issues. A comprehensive literature review finds sufficient evidence of an association between damp indoor environments and some upper respiratory tract symptoms, coughing, wheezing, and asthma symptoms in sensitized persons. This important book will be of interest to a wide-ranging audience of science, health, engineering, and building professionals, government officials, and members of the public.
Download or read book Food Safety Mycotoxins written by Aibo Wu and published by Springer Nature. This book was released on 2019-11-08 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are increasingly attracting attention at thegovernmental, public and academic level worldwide, due to more frequent and serious contaminations of food and feedstuffs, which pose a serious threat to human health and animal production. This book reviews the latest research on mycotoxins that directly concern food safety, and especially focuses on detection technologies, risk assessment and control strategiescurrently being used in China. Gathering contributions from over 20 respected researchers, the book will benefit graduatestudents, researchers and management groups from various disciplines, including food science and technology, analytical chemistry, plant pathology, public health, etc.
Download or read book Revival Trichothecene Mycotoxicosis Pathophysiologic Effects 1989 written by Val Richard Beasley and published by CRC Press Revivals. This book was released on 2019-01-28 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cover -- Title Page -- Copyright Page -- TABLE OF CONTENTS -- Volume I -- Chapter 1 The Natural Occurrence of Trichothecenes -- Chapter 2 Biochemical Mechanism of Action of Trichothecene Mycotoxins -- Chapter 3 The Distribution, Metabolism, and Excretion of Trichothecene Mycotoxins -- Chapter 4 Mutagenicity and Carcinogenicity of T-2 Toxin -- Chapter 5 Anticancer Properties of Trichothecenes -- Chapter 6 Lethal Toxicity and Nonspecific Effects -- Chapter 7 Reproductive Toxicology of Trichothecenes -- Chapter 8 Acute Respiratory Tract Toxicity of the Trichothecene Mycotoxin, T-2 Toxin -- Index
Download or read book Illustrated Toxicology written by P.K. Gupta and published by Academic Press. This book was released on 2018-04-04 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrated Toxicology: With Study Questions is an essential, practical resource for self-study and guidance catering to a broad spectrum of students. This book covers a range of core toxicological areas, including pesticides, radioactive materials and poisonous plants, also presenting a section on veterinary toxicology. Across 16 chapters, the book presents key concepts with the aid of over 250 detailed, full-color illustrations. Each section is supplemented with practical exercises to support active learning. This combination of clear illustrations and sample testing will help readers gain a deeper understanding of toxicology. This book is useful for toxicology, pharmacy, medical and veterinary students, and also serves as a refresher for academics and professionals in the field, including clinical pharmacists, forensic toxicologists, environmentalists and veterinarians. Includes comprehensive coverage of key toxicological concepts for study and revision Provides a visual learning aid with over 250 full-color illustrations Enhances understanding and memory retention of core concepts with the use of practical exercises
Download or read book Nanomaterials in Chromatography written by Chaudhery Mustansar Hussain and published by Elsevier. This book was released on 2018-06-08 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials in Chromatography: Current Trends in Chromatographic Research Technology and Techniques provides recent advancements in the wide variety of chromatographic techniques applied to nanotechnology. As nanomaterials’ unique properties can improve detection sensitivity and miniaturize the devices used in analytical procedures, they can substantially affect the evaluation and analysis ability of scientists and researchers and foster exciting developments in separation science. The book includes chapters on such crucial topics as the use of nanomaterials in sample preparation and the legalization of nanomaterials, along with a section on reducing the cost of the analysis process, both in terms of chemicals and time consumption. Presents several techniques for nanomaterials in chromatography, including well-known materials like carbon nanomaterials and functionalized nanomaterials Includes suggested readings at the end of each chapter for those who need further information or specific details, from standard handbooks, to journal articles Covers not only applications of nanomaterials in chromatography, but also their environmental impact in terms of toxicity and economic effects
Download or read book Fungal Toxins written by Solomon Kadis and published by Elsevier. This book was released on 2013-10-22 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields. The text is divided into three sections. Section A covers coumarins — its isolation, identification, biological action, natural occurrence, and uses. Section B deals with the epizootiology, clinical characteristics, and pathological findings of Stachybotryotoxicosis. Section C talks about phytopathogenic and helminthosporium toxins, toxic peptides found in Amanita species as well as other mushroom toxins, compounds accumulating in plants after an infection, and ergot. The book is recommended for microbiologists and toxicologists, especially those who would like to know more about the toxins produced by algae and fungi and their effects.
Download or read book Trichothecene Mycotoxicosis Pathophysiologic Effects 1989 written by Val Richard Beasley and published by CRC Press. This book was released on 2017-11-22 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are instances of unresolved differences of opinion , as in the case of underlying biochemical mechanisms of action. It has been particularly challenging to interpret the diversity of effects induced by several trichothecenes when studied in various cells, tissues, and concentrations, and at dissimilar intervals. In the hope of shortening the time needed to overcome these difficulties, the authors have sought to discuss a range of observations delineating both areas of agreement and aspects remaining to be clarified. The final chapter of the volumes is comprised of an effort to integrate the various observations detailed throughout the book. With the continued efforts of not only the many dedicated scientists who served as contributors to these volumes, but from the many other authors cited herein and those to follow, out understanding of these interesting compounds will continue to expand. We have already learned enough to greatly reduce the adverse effects of the trichothecene mycotoxins on humans and other animals.
Download or read book Clinical Neurotoxicology E Book written by Michael R. Dobbs and published by Elsevier Health Sciences. This book was released on 2009-07-22 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.
Download or read book Optical Biosensors written by Frances S. Ligler and published by Elsevier. This book was released on 2011-10-13 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Biosensors, Second Edition describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field. Comprehensive analysis and review of the underlying principles by optical biosensors Updates and informs on all the latest developments and hot topic areas Evaluates current methods showing the advantages and disadvantages of various systems involved
Download or read book Handbook of Secondary Fungal Metabolites written by Richard J. Cole and published by Gulf Professional Publishing. This book was released on 2003 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set is a desirable reference for a wide range of specialists who study secondary fungal metabolites ranging from pharmaceutical house researchers, agricultural researchers, those involved in food and feed control regulation, and veterinary researchers. It discusses in depth the molecular formula of, the molecular weights of, and fungal/plant source indexes of secondary fungal metabolites.
Download or read book Mycotoxins and Food Safety written by Jonathan W. DeVries and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins, from the Greek "mukes" referring to fungi or slime molds and toxin from the Latin "toxicum" referencing a poison for arrows, have earned their reputation for being potentially deleterious to the health and well being of a consuming organism, whether it be animal or human. Unfortunately, mycotoxins are a ubiquitous factor in the natural life cycle of food producing plants. As such, control of the potential impact of mycotoxins on food safety relies heavily upon accurate analysis and surveys followed by commodity segregation and restricted use or decontamination through processing. The purpose of this book is to provide the most comprehensive and current information on the topic of mycotoxins and assuring food safety. Chapters represented in the book reflect such diverse topics ranging from occurrence and impact, analysis, reduction through processing and plant breeding, toxicology and safety assessments to regulatory perspectives. Authors represent a range of international perspectives.
Download or read book Oxford Textbook of Medical Mycology written by Christopher C. Kibbler and published by Oxford University Press. This book was released on 2017-12-14 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.
Download or read book LC MS MS Method for Mycotoxin Analysis written by Aldo Laganà and published by MDPI. This book was released on 2018-07-09 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "LC-MS/MS Method for Mycotoxin Analysis" that was published in Toxins
Download or read book Nanomycotoxicology written by Mahendra Rai and published by Academic Press. This book was released on 2019-08-24 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge. Discusses the role of nanotechnology in mycotoxicology Explores the application of nanomaterials for detection of mycotoxins Covers the role of nanotechnology in the management of mycotoxins and mycotoxigenic fungi
Download or read book Biotechnology and Biology of Trichoderma written by Vijai G. Gupta and published by Newnes. This book was released on 2014-02-17 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology and Biology of Trichoderma serves as a comprehensive reference on the chemistry and biochemistry of one of the most important microbial agents, Trichoderma, and its use in an increased number of industrial bioprocesses for the synthesis of many biochemicals such as pharmaceuticals and biofuels. This book provides individuals working in the field of Trichoderma, especially biochemical engineers, biochemists and biotechnologists, important information on how these valuable fungi can contribute to the production of a wide range of products of commercial and ecological interest. Provides a detailed and comprehensive coverage of the chemistry, biochemistry and biotechnology of Trichoderma, fungi present in soil and plants Includes most important current and potential applications of Trichoderma in bioengineering, bioprocess technology including bioenergy & biofuels, biopharmaceuticals, secondary metabolites and protein engineering Includes the most recent research advancements made on Trichoderma applications in plant biotechnology and ecology and environment
