Download or read book Thermal Degradation of Polymeric Materials written by Krzysztof Pielichowski and published by Elsevier. This book was released on 2022-11-05 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thermal Degradation of Polymeric Materials, Second Edition offers a wealth of information for polymer researchers and processors who require a thorough understanding of the implications of thermal degradation on materials and product performance. Sections cover thermal degradation mechanisms and kinetics, as well as various techniques, such as thermogravimetry in combination with mass spectroscopy and infrared spectrometry to investigate thermal decomposition routes. Other chapters focus on polymers and copolymers, including polyolefins, styrene polymers, polyvinyl chloride, polyamides, polyurethanes, polyesters, polyacrylates, natural polymers, inorganic polymers, high temperature-resistant and conducting polymers, blends, organic-inorganic hybrid materials, nanocomposites, and biocomposites. Finally, other key considerations such as recycling of polymers by thermal degradation, thermal degradation during processing, and modelling, are discussed in detail. Explains mechanisms of polymer degradation, making it possible to understand and predict material behavior at elevated temperatures Offers systematic coverage of each polymer group that is supported by data detailed explanations and critical analysis Investigates thermal decomposition routes in new materials, such as organic-inorganic hybrid materials and polymer nanocomposites

Download or read book Activation Degradation written by Marina J. Lostetter and published by HarperCollins. This book was released on 2021-09-28 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Murderbot Diaries makes first contact in this new, futuristic, standalone novel exploring sentience and artificial intelligence through the lenses of conflicted robot hero Unit Four, from Marina Lostetter, critically acclaimed author of Noumenon, Noumenon Infinity, and Noumenon Ultra. When Unit Four—a biological soft robot built and stored high above the Jovian atmosphere—is activated for the first time, it’s in crisis mode. Aliens are attacking the Helium-3 mine it was created to oversee, and now its sole purpose is to defend Earth’s largest energy resource from the invaders in ship-to-ship combat. But something’s wrong. Unit Four doesn’t feel quite right. There are files in its databanks it can’t account for, unusual chemical combinations roaring through its pipes, and the primers it possesses on the aliens are suspiciously sparse. The robot is under orders to seek and destroy. That’s all it knows. According to its handler, that’s all it needs to know. Determined to fulfill its directives, Unit Four launches its ship and goes on the attack, but it has no idea it’s about to get caught in a downward spiral of misinformation, reprograming, and interstellar conflict. Most robots are simple tools. Unit Four is well on its way to becoming something more....

Download or read book Polymer Degradation Mechanisms written by United States. National Bureau of Standards and published by . This book was released on 1953 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Organic Chemistry of Drug Degradation written by Min Li and published by Royal Society of Chemistry. This book was released on 2015-10-20 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vast majority of drugs are organic molecular entities. A clear understanding of the organic chemistry of drug degradation is essential to maintaining the stability, efficacy, and safety of a drug product throughout its shelf-life. During analytical method development, stability testing, and pharmaceutical manufacturing troubleshooting activities, one of the frequently occurring and usually challenging events would be the identification of drug degradants and understanding of drug degradation mechanisms and pathways. This book is written by a veteran of the pharmaceutical industry who has first-hand experience in drug design and development, drug degradation mechanism studies, analytical development, and manufacturing process troubleshooting and improvement. The author discusses various degradation pathways with an emphasis on the mechanisms of the underlying organic chemistry, which should aid greatly in the efforts of degradant identification, formulation development, analytical development, and manufacturing process improvement. Organic reactions that are significant in drug degradation will first be reviewed and then illustrated by examples of drug degradation reported in the literature. The author brings the book to a close with a final chapter dedicated to the strategy for rapid elucidation of drug degradants with regard to the current regulatory requirements and guidelines. One chapter that should be given special attention is Chapter 3, Oxidative Degradation. Oxidative degradation is one of the most common degradation pathways but perhaps the most complex one. This chapter employs more than sixty drug degradation case studies with in-depth discussion in regard to their unique degradation pathways. With the increasing regulatory requirements on the quality and safety of pharmaceutical products, in particular with regard to drug impurities and degradants, the book will be an invaluable resource for pharmaceutical and analytical scientists who engage in formulation development, analytical development, stability studies, degradant identification, and support of manufacturing process improvement. In addition, it will also be helpful to scientists engaged in drug discovery and development as well as in drug metabolism studies.

Download or read book Thermal Degradation of Wood Components written by Francis C. Beall and published by . This book was released on 1970 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Osteoarthritis Inflammation and Degradation written by Joseph A. Buckwalter and published by IOS Press. This book was released on 2007 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoarthritis is a public health issue due to its impact in term of handicap. Regarded as a multi-factorial disease, mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration. This book helps readers understand the secrets of this disease.

Download or read book Photocatalytic Degradation of Dyes written by Sushma Dave and published by Elsevier. This book was released on 2021-08-09 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photocatalytic Degradation of Dyes: Current Trends and Future Perspectives covers in detail current trends and future aspects on photocatalytic degradation of organic dyes using novel photocatalytic techniques such as metallic nanoparticles, heterogeneous and hybrid systems using visible light irradiation. It highlights the most recent scientific and technological achievements and importance of degradation of dyes in the textile effluent by simple environmental friendly approaches using eco-friendly catalysts. It is of assistance to everyone interested in bioremediation of effluents: professionals, consulting engineers, academicians, and research scholars as well. Describes the basic photocatalytic techniques and their application in wastewater treatment Covers the key reactive species accounting for the photodegradation of different dyes, providing helpful guidelines that could be applied to foster the development of efficient photodegradation systems Includes Description of a wide variety of catalysts and their application in degradation of dyes in the effluent of variable matrices (such as textile effluent, pharmaceutical industry effluent, food industry effluent) Presents the application of doped semiconductors in the degradation of dyes, hybrid systems and their importance in the dye degradation Describes the biological synthesis of metallic nanostructures and their use in dye degradation using visible range of light irradiation Discusses the mechanistic aspect of the dye degradation using photo catalysts

Download or read book Ubiquitin Chains Degradation and Beyond written by Arnab De and published by Springer. This book was released on 2015-03-10 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to directly test the role of regulatory ubiquitination in NF-kB signaling in vivo. The case for regulatory ubiquitination has been to a large extent predicated upon the presumed deubiquitinase activity of A20, long considered a key regulator of inflammatory responses as mice lacking A20 die from multi-organ inflammation and cachexia. The theses reports the creation and characterization of a knock-in mouse that expresses a mutated form of A20 which selectively lacks the deubiquitinase activity. The knock-in mice surprisingly display completely normal NF-κB activation with no accompanying inflammatory phenotype. Given that the presumed role of A20 as a deubiquitinase has been used to support the importance of regulatory K63-linked ubiquitination in NF-kB signaling, this study will help focus future research efforts into alternative target pathways that do not depend on K63 ubiquitination. In fact, the work suggests that it might be important to revisit the role of K63-linked polyubiquitination in cell-signalling. Ubiquitin Chains: Degradation and Beyond is essential reading for anyone conducting research in cell-signalling and immunology. Dr. Arnab De received his PhD from the Department of Microbiology & Immunology at Columbia University. During his PhD, he developed transgenic mice to study the mechanism of action of a critical tumor-suppressor called A20. He is also well known for having developed peptide-based prodrugs as therapeutics for diabetes. His work has been reported by the media, and has resulted in multiple patents and publications in peer reviewed journals. He presented his findings at the American Peptide Symposium and was awarded the Young Investigator’s Award. He is the author of the book entitled Application of Peptide-Based Prodrug Chemistry in Drug Development, with a foreword written by Professor Jean Martinez (Former President, European Peptide Society) and published in the series SpringerBriefs in Pharmaceutical Science & Drug Development. His research interests lie at the intersection of chemistry and medicine. Besides biomedical research, he is also generally interested in public health policy and general scientific outreach.

Download or read book Autophagy Infection and the Immune Response written by William T. Jackson and published by John Wiley & Sons. This book was released on 2014-12-03 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication. Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma. Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.

Download or read book Chemical Physics of Polymer Degradation And Stabilization written by N. Nikolai Markovich Emanuel' and published by VSP. This book was released on 1987-06 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Immunomodulation of Innate Immune Cells written by Catarina R. Almeida and published by Frontiers Media SA. This book was released on 2020-03-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Durability 2000 written by Warren D. Ketola and published by ASTM International. This book was released on 2000 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawn from a January 2000 symposium held in New Orleans, the 13 papers in this collection discuss characterization of materials that have been subjected to exposure tests; advances and new developments in outdoor, indoor and laboratory accelerated tests; and service life prediction. Topics include t

Download or read book Bio Based Nanomaterials written by Ajay Kumar Mishra and published by Elsevier. This book was released on 2022-02-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-based Nanomaterials: Synthesis Protocols, Mechanisms and Applications summarizes recent developments in biocompatible and biodegradable materials, including their properties, fabrication methods, synthesis protocols and applications. The extensive use of petrochemicals, rising levels of plastic waste and manufacturing of non-biodegradable materials is a major environmental problem across the globe. Bio-based nanomaterials offer potential alternatives to address these challenging issues. The book covers key bio-based nanomaterials - including chitin, starch and nanocellulose – detailing their core properties, associated fabrication methods and synthesis protocols. Later chapters look at the range of applications for bio-based nanomaterials, from food and agriculture to environmental and biomedical. This book offers a detailed reference for those interested in sustainable nanoscale materials, including materials scientists, biomedical engineers, environmental scientists, food and agriculture manufacturers and scientists. Covers a range of available bio-based nanomaterials, including chitin, starch and nanocellulose Details the properties and characteristics of each bio-based nanomaterial, focusing on biocompatibility and biodegradability of sustainable materials Reviews the fabrication methods and synthesis protocols available, discussing the pros and cons of each

Download or read book Analysis of Pesticides in Water written by Alfred S.Y. Chau and published by CRC Press. This book was released on 2018-01-18 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, collected by Mr. Chau and Dr. Afghan, is devoted to the broad and important topic of pesticides. It examines important facets such as the significance of the problem, the chemistry of pesticides, and principles and techniques. It will provide excellent reference material for producers, users and testing agencies.

Download or read book The Plasticity of Skeletal Muscle written by Kunihiro Sakuma and published by Springer. This book was released on 2017-03-01 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent advances and various topics in plasticity of skeletal muscle from the perspectives of morphology, biological function, and clinical applications. Skeletal muscle is a highly plastic organ to adapt to environmental various demands, appears to endocrine various myokines, which flow into blood to protect the recognizing function of brain and inhibit the appearance of several cancer tumorigenesis. The book deals with current stem-cell based, pharmacological, and nutritional therapies for muscle wasting (sarcopenia, cachexia, and muscular dystrophy). It also explains the roles of biological mediators such as PGC-1, transient receptor potential cation channels (TRPC), and AMPK in modulating muscle function. The functional roles of ubiquitin-proteasome system, autophagy-dependent signaling in muscle homeostasis, ribosome biogenesis, and redox regulation of mechanotransduction to modulate skeletal muscle mass are also covered. It is an essential resource for physicians, researchers, post-docs as well as graduate students in the field of sports science including rehabilitation therapy, exercise physiology, exercise biochemistry, and molecular biology dealing with skeletal muscle.

Download or read book Spirochetes and Immune Evasion Infection Persistence and Clearance written by Maria Gomes-Solecki and published by Frontiers Media SA. This book was released on 2020-06-04 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interface between spirochetes and the immune response is of significant importance to their pathogenesis and persistence. Evasion from the immune system leads to infections that present as Leptospirosis, Syphilis, Lyme Disease and Relapsing Fever and may lead to putative persistence and latency. Understanding the mechanisms involved in immune evasion will shed light not only on the hostpathogen factors involved in the process but also on how resistance to infection leads to protection. Broad examples include spirochetal interaction with the immune system, spirochetal molecules involved in immune evasion and in immune activation, innate immune responses in the skin and other compartments, factors involved in spirochetal adhesion to the extracellular matrix, interaction of spirochetes with antigen presenting cells, in vitro, ex vivo or in vivo, spirochetal lipoproteins and immunity. Specific examples include innate immunity to pathogenic spirochetes (T. pallidum, B. burgdorferi and Leptospira spp.), invasion and pathogenesis by L. interrogans, subversion and suppression of B cell responses by B. burgdorferi, role of antibody in clearance versus persistence of relapsing fever Borreliae, evasion of the complement system by B. burgdorferi, immune suppression by Ixodes tick saliva for effective transmission, adhesins and enzymes involved in dissemination of T. pallidum, spirochetal variable surface proteins in immune evasion, intravital imaging of pathogenic spirochetes (Borreliae and Leptospira) in host tissues, spirochete-host surface interactions. Additional specific examples for B. burgdorferi include novel approaches to control infection within the vector and/or in mammal; tick innate immune defenses and interaction of Ixodes scapularis salivary immunomodulatory molecules with human immune cells, tick-innate immune defenses (from the perspective of the tick midgut), mouse models of infection and genetic basis for pathogenicity, diverse roles of outer surface protein C. Additional specific examples for Leptospirosis include animal models of acute, sub-lethal and persistent infection; neutrophils and innate immune response; Toll-like receptor mediated B cell responses; markers of endothelial cell activation for disease severity in human leptospirosis, corticosteroid treatment of advanced human leptospirosis, and urinary biomarkers of chronic Leptospirosis.

Download or read book Handbook of Environmental Degradation of Materials written by Myer Kutz and published by William Andrew. This book was released on 2018-06-15 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Environmental Degradation of Materials, Third Edition, explains how to measure, analyze and control environmental degradation for a wide range of industrial materials, including metals, polymers, ceramics, concrete, wood and textiles exposed to environmental factors, such as weather, seawater, and fire. This updated edition divides the material into four new sections, Analysis and Testing, Types of Degradation, Protective Measures and Surface Engineering, then concluding with Case Studies. New chapters include topics on Hydrogen Permeation and Hydrogen Induced Cracking, Weathering of Plastics, the Environmental Degradation of Ceramics and Advanced Materials, Antimicrobial Layers, Coatings, and the Corrosion of Pipes in Drinking Water Systems. Expert contributors to this book provide a wealth of insider knowledge and engineering expertise that complements their explanations and advice. Case Studies from areas such as pipelines, tankers, packaging and chemical processing equipment ensure that the reader understands the practical measures that can be put in place to save money, lives and the environment. Introduces the reader to the effects of environmental degradation on a wide range of materials, including metals, plastics, concrete, wood and textiles Describes the kind of degradation that effects each material and how best to protect it Includes case studies that show how organizations, from small consulting firms, to corporate giants design and manufacture products that are more resistant to environmental effects