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Book Helvetica Chimica Acta

Download or read book Helvetica Chimica Acta written by and published by . This book was released on 1918 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Acta chimica

Download or read book Acta chimica written by and published by . This book was released on 1982 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nr. 64. Śladkowska, J. Polynômes quasi-univalents et univalents. 1960.

Book Acta Chimica Hungarica

Download or read book Acta Chimica Hungarica written by and published by . This book was released on 1993 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Compendium of Analytical Nomenclature

Download or read book Compendium of Analytical Nomenclature written by Henry Freiser and published by Wiley-Blackwell. This book was released on 1989 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compendium will be invaluable to all who need to use the officially recommended analytical nomenclature adopted by the International Union of Pure and Applied Chemistry. Prior to 1977, these recommendations were only available in the individual reports.

Book Helvetica chimica acta

Download or read book Helvetica chimica acta written by and published by . This book was released on 1963 with total page 1290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cisplatin

    Book Details:
  • Author : Bernhard Lippert
  • Publisher : John Wiley & Sons
  • Release : 1999
  • ISBN : 9783906390208
  • Pages : 628 pages

Download or read book Cisplatin written by Bernhard Lippert and published by John Wiley & Sons. This book was released on 1999 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: 30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics such as - the chemistry and biochemistry of cisplatin, - the clinical status of Pt anticancer drugs, - the impact of cisplatin on inorganic and coordination chemistry, - new developments in drug design, testing and delivery. It also includes a chapter describing the historical development of the discovery of cisplatin. The ultimate question - How does cisplatin kill a cell? - is yet to be answered, but there are now new links suggesting how Pt binding to DNA may trigger a cascade of cellular reactions that eventually result in apoptosis. p53 and a series of damage recognition proteins of the HMG-domain family appear to be involved. The book addresses the problem of mutagenicity of Pt drugs and raises the question of the possible relevance of the minor DNA adducts, e.g. of interstrand cross-links, and the possible use of trans-(NH3)2Pt(II)-modified oligonucleotides in antisense and antigene strategies. Our present understanding of reactions of cisplatin with DNA is based upon numerous model studies (from isolated model nucleobases to short DNA fragments) and application of a large body of spectroscopic and other physico-chemical techniques. Thanks to these efforts there is presently no other metal ion whose reactions with nucleic acids are better understood than Pt. In a series of chapters, basic studies on the interactions of Pt electrophiles with nucleobases, oligonucleotides, DNA, amino acids, peptides and proteins are reported, which use, among others, sophisticated NMR techniques or X-ray crystallography, to get remarkable understanding of details on such reactions. Reactivity of cisplatin, once bound to DNA and formerly believed to be inert enough to stay, is an emerging phenomenon. It has (not yet) widely been studied but is potentially extremely important. Medicinal bioinorganic chemistry - the role of metal compounds in medicine - has received an enormous boost from cisplatin, and so has bioinorganic chemistry as a whole. There is hardly a better example than cisplatin to demonstrate what bioinorganic chemistry is all about: The marriage between classic inorganic (coordination) chemistry and the other life sciences - medicine, pharmacy, biology, biochemistry. Cisplatin has left its mark also on areas that are generally considered largely inorganic. The subject of mixed-valance Pt compounds is an example: From the sleeping beauty it made its way to the headlines of scientific journals, thanks to a class of novel Pt antitumor agents, the so-called "platinum pyrimidine blues". In the aftermath diplatinum (III) compounds were recognized and studies in large numbers, and now an organometalic chemistry of these diplatinum (III) species is beginning to emerge. The final section of the book is concerned with new developments such as novel di- and trinuclear Pt(II) drugs with DNA binding properties different from those of cisplatin, with orally active Pt(IV) drugs which are presently in clinical studies, and with attempts to modify combinatorial chemistry in such a way that it may become applicable to fast screening of Pt antitumor drugs. The potential of including computational methods in solving questions of Pt-DNA interactions is critically dealt with in the concluding chapter.

Book Theoretica Chimica Acta

Download or read book Theoretica Chimica Acta written by and published by . This book was released on 1988 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Energy Data Base

Download or read book Energy Data Base written by and published by . This book was released on 1984 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Bibliographies and Literature of Agriculture

Download or read book Bibliographies and Literature of Agriculture written by and published by . This book was released on 1983 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Lipidomics

    Book Details:
  • Author : Xianlin Han
  • Publisher : John Wiley & Sons
  • Release : 2016-05-02
  • ISBN : 1118893123
  • Pages : 48 pages

Download or read book Lipidomics written by Xianlin Han and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the area of lipidomics from fundamentals and theory to applications Presents a balanced discussion of the fundamentals, theory, experimental methods and applications of lipidomics Covers different characterizations of lipids including Glycerophospholipids; Sphingolipids; Glycerolipids and Glycolipids; and Fatty Acids and Modified Fatty Acids Includes a section on quantification of Lipids in Lipidomics such as sample preparation; factors affecting accurate quantification; and data processing and interpretation Details applications of Lipidomics Tools including for Health and Disease; Plant Lipidomics; and Lipidomics on Cellular Membranes

Book Information Circular

Download or read book Information Circular written by and published by . This book was released on 1959 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Nuclear Science Abstracts

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1964 with total page 1486 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Helium

    Book Details:
  • Author : Carla W. Cherry
  • Publisher :
  • Release : 1968
  • ISBN :
  • Pages : 536 pages

Download or read book Helium written by Carla W. Cherry and published by . This book was released on 1968 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Extraction Chromatography

Download or read book Extraction Chromatography written by and published by Elsevier. This book was released on 1975-06-01 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extraction Chromatography

Book Acta Chimica Sinica

Download or read book Acta Chimica Sinica written by and published by . This book was released on 1966 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book INIS

Download or read book INIS written by International Nuclear Information System and published by . This book was released on 2006 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Determination of Metals in Natural and Treated Water

Download or read book Determination of Metals in Natural and Treated Water written by T R Crompton and published by CRC Press. This book was released on 2001-09-20 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Determination of Metals in Natural and Treated Waters draws together all the available literature and presents in a systematic fashion the latest analytical techniques for detecting metals in non-saline and saline natural and treated water. Broad outlines of different methods and their applicability in certain situations are given allowing the chemist to choose appropriate test methods. This volume is an essential reference for environmental analytical chemists, toxicologists and the medical community in the water, agrochemistry, fisheries and waste management industries and the public sector, including enforcement and public health.