Download or read book Accurate Determination of Curium and Californium Isotopic Ratios by Inductively Coupled Plasma Quadrupole Mass Spectrometry ICP QMS in 248Cm Samples for Transmutation Studies written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The French Atomic Energy Commission has carried out several experiments including the mini-INCA (INcineration of Actinides) project for the study of minor-actinide transmutation processes in high intensity thermal neutron fluxes, in view of proposing solutions to reduce the radiotoxicity of long-lived nuclear wastes. In this context, a Cm sample enriched in 248Cm (≈97 %) was irradiated in thermal neutron flux at the High Flux Reactor (HFR) of the Laue-Langevin Institute (ILL). This work describes a quadrupole ICP-MS (ICP-QMS) analytical procedure for precise and accurate isotopic composition determination of Cm before sample irradiation and of Cm and Cf after sample irradiation. The factors that affect the accuracy and reproducibility of isotopic ratio measurements by ICP-QMS, such as peak centre correction, detector dead time, mass bias, abundance sensitivity and hydrides formation, instrumental background, and memory blank were carefully evaluated and corrected. Uncertainties of the isotopic ratios, taking into account internal precision of isotope ratio measurements, peak tailing, and hydrides formations ranged from 0.3% to 1.3%. This uncertainties range is quite acceptable for the nuclear data to be used in transmutation studies.
Download or read book Isotopic Analysis written by Frank Vanhaecke and published by John Wiley & Sons. This book was released on 2012-04-24 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by two very well-known and respected scientists in the field, this excellent practical guide is the first to cover the fundamentals and a wide range of applications, as well as showing readers how to efficiently use this increasingly important technique. From the contents: * The Isotopic Composition of the Elements * Single-Collector ICP-MS * Multi-Collector ICP-MS * Advances in Laser Ablation - Multi-Collector ICP-MS * Correction for Instrumental Mass Discrimination in Isotope Ratio Determination with Multi-Collector ICP-MS * Reference Materials in Isotopic Analysis * Quality Control in Isotope Ratio Applications * Determination of Trace Elements and Elemental Species Using Isotope Dilution ICP-MS * Geochronological Dating * Application of Multi-Collector ICP-MS to Isotopic Analysis in Cosmochemistry * Establishing the Basis for Using Stable Isotope Ratios of Metals as Paleoredox Proxies * Isotopes as Tracers of Elements Across the Geosphere-Biosphere Interface * Archaeometric Applications * Forensics Applications * Nuclear Applications * The Use of Stable Isotope Techniques for Studying Mineral and Trace Element Metabolism in Humans * Isotopic Analysis via Multi-Collector ICP-MS in Elemental Speciation A must-have for newcomers as well as established scientists seeking an overview of isotopic analysis via ICP-MS.
Download or read book Guidelines for Achieving High Accuracy in Isotope Dilution Mass Spectrometry IDMS written by Peter Bedson and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt: The isotope dilution mass spectrometry (IDMS) technique is well known and widely reported in the literature. However, its application can present considerable difficulties with regard to obtaining reliable results. Produced jointly by the Royal Society of Chemistry's Analytical Methods Committee and the Valid Analytical Measurement (VAM) programme, the aim of this book is to provide a simplified yet robust methodology, together with adequate guidance, to enable laboratories wishing to use the technique to obtain reliable data. The methodologies, for inorganic and organic mass spectrometry, which use exact and approximate matching, are illustrated with worked examples and clear diagrammatic representations. A comprehensive glossary of terms, references to key publications and an extensive IDMS bibliography are also provided. Clear and comprehensive in coverage, Guidelines for Achieving High Accuracy in Isotope Dilution Mass Spectrometry (IDMS) will provide valuable assistance to a wide variety of analytical chemists interested in applying the IDMS technique to their own measurement applications.
Download or read book Plasma Source Mass Spectrometry written by Scott D Tanner and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of the principles of ICP-MS and its application as an analytical technique is continually evolving and this book provides a unique snapshot of the current state-of-the-art. Plasma Source Mass Spectrometry: The New Millennium covers a diverse range of topics including the fate of the sample as it passes through the sample introduction system, chemical resolution using reaction and collision cells, various methods of mass analysis, approaches to account for spectral interferences, hyphenation methods to enable speciation, and the results of analyses ranging from natural waters and archaeological isotope ratios to organometallic speciation in biological materials. Describing explicitly the analytical methods that deal with current analytical challenges, and offering a current perspective on elemental analysis by plasma source mass spectrometry that is not to be found elsewhere, this book will be welcomed by both academics and industrialists as containing the most up-to-date information available on this burgeoning topic.
Download or read book Inductively Coupled Plasma Mass Spectrometry Handbook written by Simon M. Nelms and published by CRC Press. This book was released on 2005 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a level of detection of one part in 1015, inductively coupled plasma mass spectrometry (ICP-MS) is a highly sensitive tool in a huge range of analytical applications. Development of the technology continues rapidly, further opening up the scope for this invaluable analytical technique. Despite widespread interest and usage, little has been written to describe the analytical techniques and instrumentation in a format accessible to both new and experienced users of the technique. Inductively Coupled Plasma Mass Spectrometry Handbook provides a thorough description of ICP-MS instrumentation and techniques, giving the reader sufficient knowledge to approach the technique with confidence.
Download or read book Inductively Coupled Plasma Mass Spectrometry for Stable Isotope Metabolic Tracer Studies of Living Systems written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation focuses on the development of methods for stable isotope metabolic tracer studies in living systems using inductively coupled plasma single and dual quadrupole mass spectrometers. Sub-nanogram per gram levels of molybdenum (Mo) from human blood plasma are isolated by the use of anion exchange alumina microcolumns. Million-fold more concentrated spectral and matrix interferences such as sodium, chloride, sulfate, phosphate, etc. in the blood constituents are removed from the analyte. The recovery of Mo from the alumina column is 82[+-] 5% (n= 5). Isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-MS) is utilized for the quantitative ultra-trace concentration determination of Mo in bovine and human blood samples. The average Mo concentration in reference bovine serum determined by this method is 10.2[+-] 0.4 ng/g, while the certified value is 11.5[+-] 1.1 ng/g (95% confidence interval). The Mo concentration of one pool of human blood plasma from two healthy male donors is 0.5[+-] 0.1 ng/g. The inductively coupled plasma twin quadrupole mass spectrometer (ICP-TQMS) is used to measure the carbon isotope ratio from non-volatile organic compounds and bio-organic molecules to assess the ability as an alternative analytical method to gas chromatography combustion isotope ratio mass spectrometry (GC-combustion-IRMS). Trytophan, myoglobin, and[beta]-cyclodextrin are chosen for the study, initial observation of spectral interference of[sup 13]C[sup+] with[sup 12]C[sup 1]H[sup+] comes from the incomplete dissociation of myoglobin and/or[beta]-cyclodextrin.
Download or read book Handbook of Inductively Coupled Plasma Mass Spectrometry written by K. E. Jarvis and published by Blackie Academic and Professional. This book was released on 1992 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applications of Inductively Coupled Plasma mass Spectrometry to Radionuclide Determinations written by Roy W. Morrow and published by ASTM International. This book was released on 1995 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Papers from the October 1994 title symposium, held in Gatlinburg, Tennessee, detail techniques in inductively coupled plasma-mass spectrometry (ICP-MS) for the purpose of radionuclide determination, in sections on application areas including nuclear production; high-level waste characterization; env
Download or read book Liquid Sample Introduction in ICP Spectrometry written by José-Luis Todoli and published by Elsevier. This book was released on 2011-04-18 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inductively coupled plasma atomic or mass spectrometry is one of the most common techniques for elemental analysis. Samples to be analyzed are usually in the form of solutions and need to be introduced into the plasma by means of a sample introduction system, so as to obtain a mist of very fine droplets. Because the sample introduction system can be a limiting factor in the analytical performance, it is crucial to optimize its design and its use. It is the purpose of this book to provide fundamental knowledge along with practical instructions to obtain the best out of the technique. - Fundamental as well as practical character - Troubleshooting section - Flow charts with optimum systems to be used for a given application
Download or read book Inductively Coupled Plasma Mass Spectrometry written by Howard E. Taylor and published by Elsevier. This book was released on 2000-10-25 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inductively Coupled Plasma-Mass Spectrometry presents a concise A-Z description of inductively coupled plasma-mass spectrometry, written in layman's terms, for use in the solution of trace element analytical chemistry problems. Detailed discussion of sample introduction and data interpretation is provided. Practicing analytical chemists will be able to use this text to familiarize themselves with the principles, approaches, options, pitfalls, and advantages of ICP-MS technology. - Concise and straightforward descriptions of ICP-MS principles and instrumentation, ensuring rapid understanding of the technique and its advantages and limitations - Examples to clarify the operational characteristics of the technology - Drawings and illustrations to clarify principles, techniques, and methodology - Discussions of practical approaches to the solution of specific trace analysis problems with helpful tips on efficiently producing the most accurate and precise data - Easy-to-understand terms, so that new users of the technology will immediately benefit from the information provided - Comprehensive appendixes containing isotopic and interference data - An exhaustive compilation of literature citations for supplemental information
Download or read book Practical Inductively Coupled Plasma Spectrometry written by John R. Dean and published by John Wiley & Sons. This book was released on 2019-03-15 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new edition of this practical approach to sampling, experimentation, and applications in the field of inductively coupled plasma spectrometry The second edition of Practical Inductively Coupled Plasma Spectrometry discusses many of the significant developments in the field which have expanded inductively coupled plasma (ICP) spectrometry from a useful optical emission spectroscopic technique for trace element analysis into a source for both atomic emission spectrometry and mass spectrometry, capable of detecting elements at sub-ppb (ng mL−1) levels with good accuracy and precision. Comprising nine chapters, this new edition has been fully revised and up-dated in each chapter. It contains information on everything you need to practically know about the different types of instrumentation as well as pre- and post-experimental aspects. Designed to be easily accessible, with a ‘start-to-finish’ approach, each chapter outlines the key practical aspects of a specific aspect of the topic. The author, a noted expert in the field, details specific applications of the techniques presented, including uses in environmental, food and industrial analysis. This edition: Emphasizes the importance of health and safety; Provides advanced information on sample preparation techniques; Presents an updated chapter on inductively coupled plasma mass spectrometry; Features a new chapter on current and future development in ICP technology and one on practical trouble shooting and routine maintenance. Practical Inductively Coupled Plasma Spectrometry offers a practical guide that can be used for undergraduate and graduate students in the broad discipline of analytical chemistry, which includes biomedical science, environmental science, food science and forensic science, in both distance and open learning situations. It also provides an excellent reference for those in postgraduate training in these fields.
Download or read book Plasma Source Mass Spectroscopy written by Van Loon and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents some of the latest information available about inductively coupled plasma-mass spectrometry (ICP-MS) and applications of this instrumental technique to the analysis of a variety of materials. Written in a concise, straight-forward manner, Part one includes chapters on the principles, theory, and practice of ICP-MS. Part two features detailed chemical analysis procedures of ICP-MS. For all ICP-MS methods discussed, the authors include statements of accuracy as demonstrated by analyses of standard reference materials and comparisons with other analytical methods.
Download or read book Practical Guide to ICP MS written by Robert Thomas and published by CRC Press. This book was released on 2003-12-11 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a field insider with more than 20 years of experience in the development and application of atomic spectroscopy instrumentation, the Practical Guide to ICP-MS offers key concepts and guidelines in a reader-friendly format that is superb for those with limited knowledge of the technique. This reference discusses the fundamental principles, analytical advantages, practical capabilities, and overall benefits of ICP-MS. It presents the most important selection criteria when evaluating commercial ICP-MS equipment and the most common application areas of ICP-MS such as the environmental, semiconductor, geochemical, clinical, nuclear, food, metallurgical, and petrochemical industries.
Download or read book Inductively coupled plasma spectrometry and its applications written by Steve J. Hill and published by CRC PressI Llc. This book was released on 1998 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: ICP Spectrometry and Its Applications provides an up-to-date resource for researchers and professionals in academia and industry. Directed at analytical chemists, environmental scientists, geochemists, and earth scientists, the book outlines ICP-MS as well as applications of plasma spectrometry in environmental analysis, earth science, and food science.
Download or read book Isotope Dilution Mass Spectrometry written by Jose Alonso and published by Royal Society of Chemistry. This book was released on 2019-03-22 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isotope Dilution Mass Spectrometry (IDMS) has become an essential tool in research laboratories and is increasingly used in routine analysis labs (including environmental, food safety and clinical applications). This is the first textbook to present a comprehensive and instructive view of the theory and applications of this growing technique. The main objective of this book is to cover the theory and applications of Isotope Dilution in Analytical Chemistry. The scope is comprehensive to include elemental analysis, speciation analysis, organic analysis and biochemical and clinical analysis together with applications in metabolism studies and traceability of goods. Until now there have been no books published with the same general scope (only book chapters on particular applications). This is a textbook focused at post-graduate level covering the basic knowledge required for doctoral studies in this field. Isotope Dilution Mass Spectrometry will also outline practical applications of interest for routine testing laboratories where isotope dilution procedures are implemented or can be implemented in the future. This unique book covers all the theoretical and practical aspects of Isotope Dilution Mass Spectrometry (IDMS). Due to the increasing application of IDMS in many research laboratories and the increasing implementation of IDMS methodologies in routine testing laboratories, scientists in industry and working in or affiliated to this area will this an invaluable source of information. Concerning the theoretical aspects, the authors present a uniform theoretical background which grows from previous developments in Organic, Speciation and Elemental analysis both in their own laboratory and in other laboratories around the world. This general approach will be simpler and will also include new emerging fields such as quantitative proteomics and metabolism studies.
Download or read book Concentration Gradient Method for Improvement of Precision and Accuracy of Isotope Ratio Analysis Using Quadrupole Based Inductively Coupled Plasma mass Spectrometry written by Michail Dronov and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Explorations of Electrothermal Vaporization Inductively Coupled Plasma Time of flight Mass Spectrometry for Isotopic Analysis written by Adam Michael Rowland and published by . This book was released on 2008 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of inductively coupled plasma time-of-flight mass spectrometers (ICP-TOFMS) coupled to electrothermal vaporization (ETV) presents several unique analytical opportunities for isotopic analysis. This dissertation explores several subjects that utilize these characteristics in specific analytical applications. The viability of using the thermal programming abilities of the ETV in order to separate Rb and Sr is explored. These elements are isobaric at m/z 87, and must normally be separated prior to analysis for isotopic studies. Their disparate thermal properties allow them to be separated in time by the ETV allowing for simpler, faster isotope ratio analysis with less opportunity for contamination. A test case using standard potassium feldspar is found to produce moderately accurate and precise results. TOF instruments are of interest for isotope ratio analysis due to inherent isotope ratio precision. However, it has been observed that when operated in the analog data collection mode the isotope ratios observed possess a previously uncharacterized inaccuracy. This bias is rooted in variable detection efficiency of arriving ions, which can be corrected for with an algorithm described within. A method of determining the effective detector efficiency as a function of signal is presented, as well as an evaluation of the effectiveness of ratio correction. The use of ETV with TOF for isotope dilution analysis is explored. Correction of transient signals for efficiency effects is discussed, as well as the viability of using the autosampler for mixing of the solution and spike. A final study presents explores the combination of the ETV and TOF for analysis of a large number of elements from a brief transient signal. A library of peptide covered beads is analyzed for binding capacity to a variety of metals. Solutions containing metals stripped from the beads are analyzed to determine the binding capacity and specificity of the peptide sequence. The beads themselves are also analyzed for metal content using the ETV as an indicator of the efficiency of metal stripping off of the beads.
