Download or read book AACR Cancer Progress Report 2022 written by American Association for Cancer Research and published by . This book was released on 2022-09-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transformative research and technological innovations are driving unprecedented progress against the collection of diseases we call cancer. As the first and largest professional organization in the world dedicated to advancing all areas of cancer research and patient care, AACR has been and continues to be a catalyst for scientific breakthroughs that save and enhance the lives of cancer patients. It is also committed to increasing public understanding of cancer and advocating for increased federal funding for cancer research and related sciences. The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of AACR's educational efforts. This twelfth edition of the report highlights how research continues to extend and improve lives, including the lives of the five courageous individuals featured in the report and their family members who have shared their experiences with cancer. It also underscores how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for NIH, NCI, CDC, and FDA, is urgently needed if we are to realize our vision of eradicating cancer for all populations. The remarkable progress being made against cancer-in particular, improvements in reducing smoking rates and developments in early detection and treatment-is resulting in a steady fall in cancer death rates, and a consistent rise in the number of people who live longer after a cancer diagnosis. In fact, in the United States, the age-adjusted overall cancer death rate has been declining since the 1990s, with the reductions between 1991 and 2019 translating into nearly 3.5 million cancer deaths avoided. Additionally, the number of cancer survivors living in the United States has exceeded 18 million as of January 1, 2022. Unfortunately, certain U.S. populations, including racial and ethnic minorities and several other medically underserved groups, have not benefited equally from the advances against cancer. Complex factors referred to as social determinants of health have contributed to cancer health disparities in the United States. It is imperative that all stakeholders work together to eradicate the systemic and structural injustices that are current barriers.
Download or read book AACR Cancer Disparities Progress Report 2022 written by American Association for Cancer Research and published by . This book was released on 2022-06-08 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Launched in 2020, the AACR Cancer Disparities Progress Report 2020 to Congress and the American public is a cornerstone of the AACR's educational and advocacy efforts to achieve health equity. This second edition of the report highlights areas of recent progress in reducing cancer health disparities. It also emphasizes the vital need for continued transformative research and for increased collaborations if we are to ensure that advances against cancer benefit all patients, regardless of their race, ethnicity, age, sexual orientation, gender identity, socioeconomic status, or geographic location.
Download or read book AACR Cancer Progress Report 2023 written by American Association for Cancer Research and published by . This book was released on 2023-09-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unprecedented progress in medical research is increasing our understanding of the collection of diseases we call cancer and is driving improvements in cancer prevention, early detection, diagnosis, and treatment. These advances are made possible by investments in NIH, NCI, FDA, and CDC by the U.S. federal government. As the first and largest professional organization in the world dedicated to preventing and curing all cancers, AACR continues to be a catalyst for scientific breakthroughs that save the lives of patients with cancer. AACR is committed to increasing public understanding of cancer and advocating for increased funding for medical research.The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of AACR's educational efforts. This thirteenth edition of the report highlights how research continues to extend and improve the lives of Americans, including the lives of the eight courageous individuals featured in the report and their family members who have shared their experiences with cancer. It also underscores how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for NIH, NCI, FDA, and CDC, is urgently needed.The remarkable progress being made against cancer is resulting in a steady reduction in cancer death rates, and a consistent rise in the number of people who live longer and fuller lives after a cancer diagnosis. In fact, the overall U.S. cancer death rate has fallen by 33 percent between 1991 and 2020, a reduction that translates into averting an estimated 3.8 million deaths from cancer. The reduction in overall cancer mortality is driven largely by the decline in the U.S. lung cancer death rate, the pace of which has accelerated in recent years because of reduction in smoking and advances in early detection and treatment. Additionally, the reduction in death rates for melanoma, colorectal cancer, prostate cancer, and female breast cancer has contributed to the progress against overall U.S. cancer mortality. Notably, among U.S. children and adolescents, overall cancer death rates have declined by 70 percent and 64 percent, respectively, over the past five decades.
Download or read book The Journal of Cancer Research written by and published by . This book was released on 1916 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book AACR Cancer Progress Report 2021 written by American Association for Cancer Research and published by . This book was released on 2021-10-13 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Highlights of Progress in Research on Cancer written by and published by . This book was released on 1960 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Drug Development Paradigm in Oncology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-02-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.
Download or read book Cancer Progress Report written by and published by . This book was released on 2001 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book AACR Cancer Progress Report 2020 written by American Association for Cancer Research and published by . This book was released on 2020-09-23 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The annual AACR Cancer Progress Report to Congress and the American public is a cornerstone of the AACR's educational and advocacy efforts. This tenth edition of the report highlights how research continues to extend and improve lives, like the lives of the courageous individuals featured in the report who have shared their experiences with cancer. It also underscores how the COVID-19 pandemic has negatively affected cancer science and medicine, as well as how unwavering, bipartisan support from Congress, in the form of robust and sustained annual increases in funding for the NIH, NCI, and FDA, is vital if we are to accelerate the pace of progress against cancer for the benefit of families everywhere.
Download or read book Delivering High Quality Cancer Care written by Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population and published by National Academies Press. This book was released on 2014-01-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the United States, approximately 14 million people have had cancer and more than 1.6 million new cases are diagnosed each year. However, more than a decade after the Institute of Medicine (IOM) first studied the quality of cancer care, the barriers to achieving excellent care for all cancer patients remain daunting. Care often is not patient-centered, many patients do not receive palliative care to manage their symptoms and side effects from treatment, and decisions about care often are not based on the latest scientific evidence. The cost of cancer care also is rising faster than many sectors of medicine--having increased to $125 billion in 2010 from $72 billion in 2004--and is projected to reach $173 billion by 2020. Rising costs are making cancer care less affordable for patients and their families and are creating disparities in patients' access to high-quality cancer care. There also are growing shortages of health professionals skilled in providing cancer care, and the number of adults age 65 and older--the group most susceptible to cancer--is expected to double by 2030, contributing to a 45 percent increase in the number of people developing cancer. The current care delivery system is poorly prepared to address the care needs of this population, which are complex due to altered physiology, functional and cognitive impairment, multiple coexisting diseases, increased side effects from treatment, and greater need for social support. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis presents a conceptual framework for improving the quality of cancer care. This study proposes improvements to six interconnected components of care: (1) engaged patients; (2) an adequately staffed, trained, and coordinated workforce; (3) evidence-based care; (4) learning health care information technology (IT); (5) translation of evidence into clinical practice, quality measurement and performance improvement; and (6) accessible and affordable care. This report recommends changes across the board in these areas to improve the quality of care. Delivering High-Quality Cancer Care: Charting a New Course for a System in Crisis provides information for cancer care teams, patients and their families, researchers, quality metrics developers, and payers, as well as HHS, other federal agencies, and industry to reevaluate their current roles and responsibilities in cancer care and work together to develop a higher quality care delivery system. By working toward this shared goal, the cancer care community can improve the quality of life and outcomes for people facing a cancer diagnosis.
Download or read book Physical Activity and Cancer written by Kerry S. Courneya and published by Springer Science & Business Media. This book was released on 2010-11-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.
Download or read book Prognosis Research in Healthcare written by Richard D. Riley and published by Oxford University Press. This book was released on 2019-01-17 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What is going to happen to me?" Most patients ask this question during a clinical encounter with a health professional. As well as learning what problem they have (diagnosis) and what needs to be done about it (treatment), patients want to know about their future health and wellbeing (prognosis). Prognosis research can provide answers to this question and satisfy the need for individuals to understand the possible outcomes of their condition, with and without treatment. Central to modern medical practise, the topic of prognosis is the basis of decision making in healthcare and policy development. It translates basic and clinical science into practical care for patients and populations. Prognosis Research in Healthcare: Concepts, Methods and Impact provides a comprehensive overview of the field of prognosis and prognosis research and gives a global perspective on how prognosis research and prognostic information can improve the outcomes of healthcare. It details how to design, carry out, analyse and report prognosis studies, and how prognostic information can be the basis for tailored, personalised healthcare. In particular, the book discusses how information about the characteristics of people, their health, and environment can be used to predict an individual's future health. Prognosis Research in Healthcare: Concepts, Methods and Impact, addresses all types of prognosis research and provides a practical step-by-step guide to undertaking and interpreting prognosis research studies, ideal for medical students, health researchers, healthcare professionals and methodologists, as well as for guideline and policy makers in healthcare wishing to learn more about the field of prognosis.
Download or read book AACR Cancer Disparities Progress Report 2020 written by American Association for Cancer Research and published by . This book was released on 2020-03-24 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer health disparities are one of the most pressing public health challenges we face today in the United States, and the AACR Cancer Disparities Progress Report 2020 highlights areas of progress in addressing this challenge. It also emphasizes the need for continued research and for increased collaboration among stakeholders if we are to achieve the bold vision of health equity. Racial and ethnic minorities are among the populations groups that have long experienced significant cancer health disparities, although progress in the form of narrowing of the disparities in the overall cancer death rate among racial and ethnic groups in the United States is evident in recent years. We have also made progress in deepening our understanding of the many complex factors that contribute to cancer health disparities. Most important among these are social, clinical, behavioral, cultural, psychological, environmental, and genetic and biological factors. Unfortunately, as pointed out in the report, most data on cancer biology comes from white individuals and there is an urgent need for much more research to increase our understanding of the genes and mutations associated with cancer in racial and ethnic minorities.Despite recent advances in cancer treatment, racial and ethnic minorities are often less likely to receive the standard of care recommended for the type and stage of cancer with which they have been diagnosed. To achieve health equity for everyone, stakeholders must work together to remove the barriers that prevent all segments of the population benefiting equally from lifesaving progress in cancer treatment, including a serious lack of racial and ethnic diversity among those who pariticipate in cancer clinical trials. Over the past decade, the field of cancer health disparities research has evolved from simply describing different outcomes among populations into an established multidisciplinary field of research. To further accelerate the pace of progress against cancer health disparities concerted efforts by all stakeholders is absolutely critical. Thus, the report concludes with a call to action to Congress. Through robust and sustained funding, Congress help us achieve the bold vision of health equity.
Download or read book Patient Derived Tumor Xenograft Models written by Rajesh Uthamanthil and published by Academic Press. This book was released on 2016-10-13 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains. In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory. Offers guidance on data interpretation and regulatory aspects Provides useful techniques and strategies for working with PDX models Includes practical tools and potential pitfalls for best practices Compiles all knowledge of PDX models research in one resource Presents the results of first ever global survey on standards of PDX development and usage in academia and industry
Download or read book Advancing the Science of Cancer in Latinos written by Amelie G. Ramirez and published by Springer Nature. This book was released on 2019-11-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.
Download or read book Policy Issues in the Development and Adoption of Biomarkers for Molecularly Targeted Cancer Therapies written by Margie Patlak and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "One of the challenges in treating cancer is the disease's complexity and variation among patients. Cancer manifests differently in each patient, so treatments that are effective in one patient may not be effective in another. As cancer care becomes more personalized, subpopulations of individuals will be given preventive or therapeutic interventions based on their susceptibility to a particular disease or their predicted response to a specific treatment. However, before the use of personalized cancer care can reach its full potential, the health care system must resolve a number of technological, regulatory, and reimbursement issues. To explore these policy challenges, the National Cancer Policy Forum held the workshop Policy Issues in the Development of Personalized Medicine in Oncology in June 2009. Experts provided presentations on the current state of personalized medicine technology, as well as issues in the validation of, regulation of, and reimbursement for the predictive tests that underpin personalized medicine. Participants discussed the obstacles and possible solutions to further developing and using personalized medicine technologies. This document summarizes the workshop"--
Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.
