Download or read book A Wireless Microsystem for Multichannel Neural Recording Microprobes written by Hao Yu and published by . This book was released on 2004 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Circuitry for a Wireless Microsystem for Neural Recording Microprobes written by and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated circuits for use in a wireless microsystem used in neural recording is described, The implantable microsystem will be powered and transmit digitized data using RF telemetry. Recorded neural signals are amplified, multiplexed, digitized using a 2nd order sigma-delta modulator, and then transmitted to the outside world by an on-chip transmitter, The circuit is designed using a standard 1.5 microns CMOS process, Several circuit blocks have been designed, fabricated and show to operate as expected.
Download or read book Single chip Wireless Microsystems for Multichannel Neural Biopotential Recording written by Pedram Mohseni and published by . This book was released on 2005 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Multichannel Wireless Neural Recording Systems Using Standard WLAN Modules and ASIC Micro system Components written by Jayant Parthasarathy and published by . This book was released on 2006 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Wireless Multichannel Microsystems for Time Share Chemical and Electrical Neural Recording written by Masoud Roham and published by . This book was released on 2010 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This project has developed single-chip wireless microsystems fabricated using a 0.5-μm double-poly triple-metal n-well CMOS process that incorporate three powerful neuromonitoring techniques: fast-scan cyclic voltammetry (FSCV) for monitoring neurotransmitter concentrations, extracellular electrophysiology for single-unit recording, and time-share recordings of these two techniques for quasi-simultaneous measurements of chemical and electrical neural activity at a single brain site in vivo. These devices also support electrical stimulation for focal activation of neural circuits. In particular, a 1.1-mW, 5-mm2, 4-channel integrated circuit has been developed that can be dynamically configured to perform neurochemical monitoring using 300-V/s FSCV and neuroelectrical recording using extracellular electrophysiology. The chip architecture uses a 76-μW, 3rd-order, continuous-time delta-sigma modulator per channel that achieves an rms input-referred noise of 56.7 pA (dc-5 kHz) and 3.5 μV (1.1-5 kHz) for chemical and electrical neuromonitoring, respectively. The chip architecture also incorporates monolithic circuitry for generating FSCV and biphasic constant-current stimulus waveforms. It has been externally interfaced with carbon-fiber microelectrodes implanted acutely in the caudate-putamen of an anesthetized rat, and enables chemically resolved monitoring of electrically evoked dopamine release and its postsynaptic bioelectrical response at the same recording site. The dopamine limit of detection corresponding to a signal-to-rms noise ratio of three is estimated to be 16.7 nM, which compares favorably with the amplitude of phasic dopamine transients that varies in the range of 40 nM-1 μM. The chip has also been packaged on a miniature rigid-flex substrate to develop an implantable device for investigating brain-behavior relationships in an ambulatory rat. The device successfully captures the effect of high-dose amphetamine administration on electrically and non-electrically evoked dopamine neurotransmission in the brain, demonstrating that the technology developed throughout the course of this project can indeed be applied to conduct neurochemical measurements in the context of behavior.
Download or read book Biomedical Materials written by Roger Narayan and published by Springer Nature. This book was released on 2020-12-09 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a comprehensive discussion of contemporary materials used in biomedical research and development. The pedagogical writing style and structure provides students with an understanding of the fundamental concepts necessary to pursue research and industrial work in this growing area of biomedical science, including characteristics of biomaterials, biological processes, biocompatibility, and applications of materials in implants and medical instruments. Written by leading researchers in the field, this volume highlights important topics associated with biomedical engineering, medicine and surgery. The revised text contains updates that reflect recent technological advances in biomedical materials. It contains information on new characterization methods and applications for biomedical materials and incorporates suggestions that were offered by readers and educators using the first edition over the years. This textbook takes the reader to the forefront of biomedical materials development, providing graduate students with a taste of how the field is changing, while also serving as a useful reference to physicians and engineers.
Download or read book Wireless Power Transfer and Data Communication for Intracranial Neural Recording Applications written by Kerim Türe and published by Springer Nature. This book was released on 2020-03-04 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes new circuits and systems for implantable wireless neural monitoring systems and explains the design of a batteryless, remotely-powered implantable micro-system, designed for continuous neural monitoring. Following new trends in implantable biomedical applications, the authors demonstrate a system which is capable of efficient remote powering and reliable data communication. Novel architecture and design methodologies are used for low power and small area wireless communication link. Additionally, hermetically sealed packaging and in-vivo validation of the implantable device is presented.
Download or read book A Wireless Microsystem for Neural Stimulating Microprobes written by Maysam Ghovanloo and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nanotechnology and Neuroscience Nano electronic Photonic and Mechanical Neuronal Interfacing written by Massimo De Vittorio and published by Springer. This book was released on 2014-07-08 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the use of modern micro- and nanofabrication technologies to develop improved tools for stimulating and recording electrical activity in neuronal networks. It provides an overview of the different ways in which the “nano-world” can be beneficial for neuroscientists, including improvement of mechanical adhesion of cells on electrodes, tight-sealed extracellular recordings or intracellular approaches with strongly reduced invasiveness and tools for localized electrical or optical stimulation in optogenetics experiments. Specific discussion of fabrication strategies is included, to provide a comprehensive guide to develop micro and nanostructured tools for biological applications. A perspective on integrating these devices with state-of-the-art technologies for large-scale in vitro and in vivo experiments completes the picture of neuronal interfacing with micro- and nanostructures.
Download or read book Biomedical Engineering Trends in Electronics written by Anthony Laskovski and published by BoD – Books on Demand. This book was released on 2011-01-08 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid technological developments in the last century have brought the field of biomedical engineering into a totally new realm. Breakthroughs in material science, imaging, electronics and more recently the information age have improved our understanding of the human body. As a result, the field of biomedical engineering is thriving with new innovations that aim to improve the quality and cost of medical care. This book is the first in a series of three that will present recent trends in biomedical engineering, with a particular focus on electronic and communication applications. More specifically: wireless monitoring, sensors, medical imaging and the management of medical information.
Download or read book A 1024 site Neural Stimulating Array with On chip Current Generation written by Ying Yao and published by . This book was released on 2005 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Low Cost End to End Multi Channel Wireless Neural Recording System written by Benjamin Donald Wood and published by . This book was released on 2018 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years neural recording and stimulation technology has advanced rapidly. As new implants and electrode devices are implemented and tested, a full system capable of effectively utilizing them within a medical application has remained unrealized. A mechanism that is able to wirelessly communicate with and control such instruments would drastically increase the ease with which they can be used in scenarios such as free-moving animal experiments, medical studies, and field trials. Certain constraints come with constructing such an end-to-end device, such as limits on power, cost, and size, along with stringent performance requirements on data rates and range. This thesis introduces a fully developed wireless neural recording system. Consisting of a multi-channel neural implant, a small microcontroller relay device, and a tablet running a control application, it is capable of recording and displaying neural data at high speed and long range. Communication between the three components is accomplished purely through wireless transmissions, utilizing inductive coils to transfer data through the patient's tissue along with an 802.11 WiFi to establish a link and facilitate transmission between the microcontroller and control software. The control software gives the researcher freedom to specify recording parameters such as the amount of data desired, sampling speed, recording channels, and format of the data to be sent from the implant. Upon data reception, the software processes the received data, creating a time series of neural points per channel that can be graphed, displayed, and downloaded. This modular and simple approach to an end-to-end wireless recording system will allow cutting edge neural implants to be quickly integrated into full solutions that can be used in neurological and biomedical research.
Download or read book A Wireless Multichannel Neural Recording Platform for Real time Brain Machine Interfaces written by Iyad Obeid and published by . This book was released on 2004 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advanced MEMS Microprobes for Neural Stimulation and Recording written by Arash Akhavan Fomani and published by . This book was released on 2011 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in-vivo observation of the neural activities generated by a large number of closely located neurons is believed to be crucial for understanding the nervous system. Moreover, the functional electrical stimulation of the central nervous system is an effective method to restore physiological functions such as limb control, sound sensation, and light perception. The Deep Brain Stimulation (DBS) is being successfully used in the treatment of tremor and rigidity associated with advanced Parkinson's disease. Cochlear implants have also been employed as an effective treatment for sensorineural deafness by means of delivering the electrical stimulation directly to the auditory nerve. The most significant contribution of this PhD study is the development of next-generation microprobes for the simultaneous stimulation and recording of the cortex and deep brain structures. For intracortical applications, millimetre length multisite microprobes that are rigid enough to penetrate into the cortex while integrated with flexible interconnection cables are demanded. In chronic applications, the flexibility of the cable minimizes the tissue damage caused by the relative micro-motion between the brain and the microprobe. Although hybrid approaches have been reported to construct such neural microprobes, these devices are brittle and may impose severe complications if they break inside the tissue. In this project, MEMS fabrication processes were employed to produce non-breakable intracortical microprobes with an improved structural design. These 32 channel devices are integrated with flexible interconnection cables and provide enough mechanical strength for penetration into the tissue. Polyimide-based flexible implants were successfully fabricated and locally reinforced at the tip with embedded 15 [mu]m-thick gold micro-needles. In DBS applications, centimetre long microprobes capable of stimulating and recording the neural activity are required. The currently available DBS probes, manufactured by Medtronic, provide only four cylindrical shaped electrode sites, each 1.5 mm in height and 1.27 mm in diameter. Although suitable for the stimulation of a large brain volume, to measure the activity of a single neuron but to avoid measuring the average response of adjacent cells, recording sites with dimensions in the range of 10 - 20 [mu]m are required. In this work, novel Three Dimensional (3D) multi channel microprobes were fabricated offering 32 independent stimulation and recording electrodes around the shaft of the implant. These microprobes can control the spatial distribution of the charge injected into the tissue to enhance the efficacy and minimize the adverse effects of the DBS treatment. Furthermore, the device volume has been reduced to one third the volume of a conventional Medtronic DBS lead to significantly decrease the tissue damage induced by implantation of the microprobe. For both DBS and intracortical microprobes, the impedance characteristics of the electrodes were studied in acidic and saline solutions. To reduce the channel impedance and enhance the signal to noise ratio, iridium (Ir) was electroplated on gold electrode sites. Stable electrical characteristics were demonstrated for the Ir and gold electrodes over the course of a prolonged pulse stress test for 100 million cycles. The functionality and application potential of the fabricated microprobes were confirmed by the in-vitro measurements of the neural activity in the mouse hippocampus. In order to reduce the number of channels and simplify the signal processing circuitry, multiport electrostatic-actuated switch matrices were successfully developed, fabricated, and characterized for possible integration with neural microprobes to construct a site selection matrix. Magnetic-actuated switches have been also investigated to improve the operation reliability of the MEMS switching devices.
Download or read book A Multi Channel Wireless Implantable Neural Recording System written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: ABSTRACT YIN, MING. A Multi-Channel Wireless Implantable Neural Recording System. (Under the direction of Dr. Maysam Ghovanloo). This dissertation presents a multi-channel implantable wireless neural recording (WINeR) system for electrophysiology and behavioral neuroscience research applications. This system consists of two units: a system-on-a-chip (SoC) transmitter unit and a receiver unit built with off-the-shelf components. A novelty of the WINeR system is in its utilization of a wireless single-slope ADC technique by inserting a wireless link in between a pulse width modulator and a time-to-digital converter (TDC). This technique not only offers the WINeR system the benefit of a single-slope ADC, but also makes the WINeR transmitter unit very simple, low power, and small in regards to chip area. In addition, by directly transmitting pulse width modulation (PWM) signal, the pulse rate over the wireless link is reduced to the sampling rate, while a moderate system resolution can still be achieved. Another novelty of this system is that its transmitter uses an asynchronous (clockless) topology and achieves very low noise levels by eliminating the on-chip clock. Some of the other features of this system are the wideband FSK demodulator and FPGA-based TDC in the receiver unit capable of achieving high resolution, low noise, low power, low cost, and ease of implementation. A 32-channel WINeR transmitter prototype is implemented in a standard CMOS technology, and operates in the 900MHz ISM band. A prototype WINeR receiver is also built using off-the-shelf components with up to 75MHz bandwidth. A custom developed VC++ GUI running on a PC interface with the receiver unit through a USB port and facilitates data storage and visualization. In addition, detailed noise analysis is conducted both theoretically and experimentally to further characterize the performance of the system. Finally, the full functionality of the entire WINeR system has been validated from bench-top.
Download or read book Neuroprosthetics written by Justin C. Sanchez and published by CRC Press. This book was released on 2018-09-03 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface. The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives. Identifying concepts and features of devices that work well with users of a direct neural interface, this book: Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals Provides an understanding of the mechanisms of neural–electrode performance and information contained in neural signals Provides understanding of neural decoding in neuroprosthetic applications Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.
Download or read book A Neural Recording Front End for Multi channel Wireless Implantable Applications written by Haitao Li and published by . This book was released on 2011 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:
