Download or read book A transi o dos cuidados na primeira inf ncia Uma tabela classificativa dos servi os de educa o e cuidados na primeira inf ncia written by Peter Adamson and published by . This book was released on 2008 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Download or read book Innovation for Systems Information and Decision written by Adiel Teixeira de Almeida and published by Springer Nature. This book was released on 2021-11-24 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Third International Meeting on Innovation for Systems Information and Decision, INSID 2021, which was held during December 1-3, 2021. The conference was initially planned to take place in Recife, Brazil, but changed to a virtual meeting due to the COVID-19 pandemic. The 9 full papers presented in this volume were carefully reviewed and selected from a total of 76 submissions. They reflect methodological improvements and advances in multi-criteria decision-making/multi-criteria decision-aid (MCDM/MCDA) oriented toward real-world applications, which contribute to the understanding of relevant developments of current research on and future trends of innovation for systems information and decision.
Download or read book Model Assisted Survey Sampling written by Carl-Erik Särndal and published by Springer Science & Business Media. This book was released on 2003-10-31 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now available in paperback, this book provides a comprehensive account of survey sampling theory and methodology suitable for students and researchers across a variety of disciplines. It shows how statistical modeling is a vital component of the sampling process and in the choice of estimation technique. The first textbook that systematically extends traditional sampling theory with the aid of a modern model assisted outlook. Covers classical topics as well as areas where significant new developments have taken place.
Download or read book Ultrasound of Congenital Fetal Anomalies written by Dario Paladini and published by CRC Press. This book was released on 2018-03-29 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most frequently asked questions that confront the fetal medicine trainee/expert on a daily basis are “Is the finding real or merely an artifact?” and “Is the diagnosis correct?”. However, to be able to find the description of an abnormal ultrasound finding in a textbook, one generally has to search by the definite diagnosis, which has not been done as yet. This uneasy feeling was the first factor that directed the layout of Ultrasound of Congenital Fetal Anomalies: Differential Diagnosis and Prognostic Indicators, Second Edition. Copiously illustrated, the book displays fetal anomalies by scanning view and descriptions of all major ultrasound planes, detailing what can be considered a normal view and what cannot. See What’s New in the Second Edition: Early detection of fetal anomalies (1214 weeks) Ultrasound in fetal infections and in twins The nuchal translucency issue, the newest intracranial translucency as well as the range of congenital anomalies detectable at this gestational age Expanded coverage of heart anomalies, including arrhythmias and early fetal echocardiography The author’s mission continues to be to provide guidance on how to quickly recognize and diagnose congenital fetal anomalies, beginning at the beginning with ultrasound sigh all the way through to final diagnosis.
Download or read book Dietary Guidelines for Americans 2015 2020 written by HHS, Office of Disease Prevention and Health Promotion (U.S.) and published by Government Printing Office. This book was released on 2015-12-31 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn more about how health nutrition experts can help you make the correct food choices for a healthy lifestyle The eighth edition of the Dietary Guidelines is designed for professionals to help all individuals, ages 2 years-old and above, and their families to consume a healthy, nutritionally adequate diet. The 2015-2020 edition provides five overarching Guidelines that encourage: healthy eating patterns recognize that individuals will need to make shifts in their food and beverage choices to achieve a healthy pattern acknowledge that all segments of our society have a role to play in supporting healthy choices provides a healthy framework in which individuals can enjoy foods that meet their personal, cultural and traditional preferences within their food budget This guidance can help you choose a healthy diet and focus on preventing the diet-related chronic diseases that continue to impact American populations. It is also intended to help you to improve and maintain overall health for disease prevention. **NOTE: This printed edition contains a minor typographical error within the Appendix. The Errata Sheet describing the errors can be found by clicking here. This same errata sheet can be used for the digital formats of this product available for free. Health professionals, including physicians, nutritionists, dietary counselors, nurses, hospitality meal planners, health policymakers, and beneficiaries of the USDA National School Lunch and School Breakfast program and their administrators may find these guidelines most useful. American consumers can also use this information to help make helathy food choices for themselves and their families.
Download or read book Preclinical Safety Evaluation of Biopharmaceuticals written by Joy A. Cavagnaro and published by John Wiley & Sons. This book was released on 2013-03-07 with total page 1012 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose responsibilities include the evaluation of novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of launching new biopharmaceuticals, and speed potentially lifesaving drugs to market. This guide covers topics ranging from lead candidate selection to establishing proof of concept and toxicity testing to the selection of the first human doses. With chapters contributed by experts in their specific areas, Preclinical Safety Evaluation of Biopharmaceuticals: A Science-Based Approach to Facilitating Clinical Trials: Includes an overview of biopharmaceuticals with information on regulation and methods of production Discusses the principles of ICH S6 and their implementation in the U.S., Europe, and Japan Covers current practices in preclinical development and includes a comparison of safety assessments for small molecules with those for biopharmaceuticals Addresses all aspects of the preclinical evaluation process, including: the selection of relevant species; safety/toxicity endpoints; specific considerations based upon class; and practical considerations in the design, implementation, and analysis of biopharmaceuticals Covers transitioning from preclinical development to clinical trials This is a hands-on, straightforward reference for professionals involved in preclinical drug development, including scientists, toxicologists, project managers, consultants, and regulatory personnel.
Download or read book Chemical Storylines written by Chris Otter and published by Vantage Press, Inc. This book was released on 2008-05 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Puts the development of chemical ideas in the context of social and industrial needs. This book uses OCR terminology, and contains a glossary of the key terms from the specification. It is structured in line with the OCR specification with colour content, photographs and illustrations.
Download or read book Science and Relativism written by Larry Laudan and published by University of Chicago Press. This book was released on 1990-08-15 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, many members of the intellectual community have embraced a radical relativism regarding knowledge in general and scientific knowledge in particular, holding that Kuhn, Quine, and Feyerabend have knocked the traditional picture of scientific knowledge into a cocked hat. Is philosophy of science, or mistaken impressions of it, responsible for the rise of relativism? In this book, Laudan offers a trenchant, wide-ranging critique of cognitive relativism and a thorough introduction to major issues in the philosophy of knowledge.
Download or read book Human Evolution written by Roger Lewin and published by Wiley-Blackwell. This book was released on 1984-01 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brief length and focused coverage of" Human Evolution: An Illustrated Introduction" have made this best-selling textbook the ideal complement to any biology or anthropology course in which human evolution is taught. The text places human evolution in the context of humans as animals, while also showing the physical context of human evolution, including climate change and the impact of extinctions. Chapter introductions, numerous drawings and photographs, and an essential glossary all add to the accessibility of this text.The fifth edition has been thoroughly updated to include coverage of the latest discoveries and perspectives, including: - New early hominid fossils from Africa and Georgia, and their implications - New archaeological evidence from Africa on the origin of modern humans - Updated coverage of prehistoric art, including new sites - New perspectives on molecular evidence and their implications for human population history.
Download or read book Birth Defects Surveillance written by World Health Organization and published by . This book was released on 2015-06-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is a collaborative effort between the World Health Organization (WHO), the National Center on Birth Defects and Developmental Disabilities (NCBDDD) from the US Centers for Disease Control and Prevention (CDC), and the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR)"--P. iii.
Download or read book People s Palaces written by Christoph Grafe and published by . This book was released on 2014 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Author Christoph Grafe investigates an architectonic typology, the cultural edifice, which must often take on the role of national identity and culture in the realisation of a democratic society. This book takes two specific projects as its subject: London's South Bank and the Kulturhus in Stockholm. The buildings were chosen as a result of their architectural meaning, and by the fact that they appeared in two countries that fulfilled a leading role in the development of the post-war 'welfare state'; in Europe. Besides an in-depth analysis of the two cities within the context of their wider national and cultural development, the book includes a photo essay by German photographer Heidi Specker" --
Download or read book Standard Methods for the Examination of Water and Sewage written by and published by . This book was released on 1913 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Archaeology of the Digital written by Frank O. Gehry and published by Sternberg Press. This book was released on 2013 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exhibition and publication constitute the first phase of a multiyear research project launched by the CCA to investigate the incorporation of digital technologies in the field of architecture.
Download or read book Modern Brazil written by Herbert S. Klein and published by Cambridge University Press. This book was released on 2020-03-12 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first social history examining all aspects of Brazil's radical transition from a predominantly rural society to an urban one.
Download or read book Postanarchism written by Saul Newman and published by John Wiley & Sons. This book was released on 2015-12-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: What shape can radical politics take today in a time abandoned by the great revolutionary projects of the past? In light of recent uprisings around the world against the neoliberal capitalist order, Saul Newman argues that anarchism - or as he calls it postanarchism - forms our contemporary political horizon. In this book, Newman develops an original political theory of postanarchism; a form of anti-authoritarian politics which starts, rather than finishes, with anarchy. He does this by asking four central questions: who are we as subjects; how do we resist; what is our relationship to violence; and, why do we obey? By drawing on a range of heterodox thinkers including La Boétie, Sorel, Benjamin, Stirner and Foucault, the author not only investigates the current conditions for radical political thought and action, but proposes a new form of politics based on what he calls ontological anarchy and the desire for autonomous life. Rather than seeking revolutionary emancipation or political hegemony, we should affirm instead the non-existence of power and the ever-present possibilities of freedom. As the tectonic plates of our time are shifting, revealing the nihilism and emptiness of our political and economic order, postanarchisms disdain for power in all its forms offers us genuine emancipatory potential.
Download or read book Group Decision and Negotiation A Multidisciplinary Perspective written by Danielle Costa Morais and published by Springer Nature. This book was released on 2020-05-12 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 20th International Conference on Group Decision and Negotiation, GDN 2020, which was planned to be held in Toronto, ON, Canada, during June 7–11, 2020. The conference was cancelled due to the Coronavirus pandemic. Nevertheless, it was decided to publish the proceedings, because the review process had already been completed at the time the cancellation was decided. The field of Group Decision and Negotiation focuses on decision processes with at least two participants and a common goal but conflicting individual goals. Research areas of Group Decision and Negotiation include electronic negotiations, experiments, the role of emotions in group decision and negotiations, preference elicitation and decision support for group decisions and negotiations, and conflict resolution principles. The 14 full papers presented in this volume were carefully reviewed and selected from 75 submissions. They were organized in topical sections named: Conflict Resolution, Preference Modeling for Group Decision and Negotiation, Intelligent Group Decision Making and Consensus Process, Collaborative Decision Making Processes.
