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Book Human Herpesviruses

    Book Details:
  • Author : Ann Arvin
  • Publisher : Cambridge University Press
  • Release : 2007-08-16
  • ISBN : 1139461648
  • Pages : 1325 pages

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Book A Structural and Functional Analysis of Herpes Simplex Virus Type 1 Glycoprotein L  an Essential Component of the Viral Fusogenic Complex

Download or read book A Structural and Functional Analysis of Herpes Simplex Virus Type 1 Glycoprotein L an Essential Component of the Viral Fusogenic Complex written by Michael J. Novotny and published by . This book was released on 1996 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Structure function Analysis of the Herpes Simplex Virus Type 1 Origin Binding Protein  UL9

Download or read book Structure function Analysis of the Herpes Simplex Virus Type 1 Origin Binding Protein UL9 written by Ajay Kumar Malik and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Characterization of the Chromatin Structure of the Herpes Simplex Virus Type 1  HSV 1  ICP22 Promoter in an Episomal Vector

Download or read book Characterization of the Chromatin Structure of the Herpes Simplex Virus Type 1 HSV 1 ICP22 Promoter in an Episomal Vector written by Shao-Chung Hsia and published by . This book was released on 1999 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Further Characterization of the UL37 Protein of Herpes Simplex Virus Type 1 and Its Interaction with ICP8  the Major DNA binding Protein of Herpes Simplex Virus

Download or read book Further Characterization of the UL37 Protein of Herpes Simplex Virus Type 1 and Its Interaction with ICP8 the Major DNA binding Protein of Herpes Simplex Virus written by Allen G. Albright and published by . This book was released on 1994 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Herpes Simplex Virus 1 DNA Packaging

Download or read book Herpes Simplex Virus 1 DNA Packaging written by Ying Fan and published by . This book was released on 1997 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Characterization of Expression of the Herpes Simplex Virus Type 1 ICP22 and Us1 5 Proteins

Download or read book Characterization of Expression of the Herpes Simplex Virus Type 1 ICP22 and Us1 5 Proteins written by John Jason Bowman and published by . This book was released on 2008 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using this system and newly generated C-terminal specific ICP22 Abs, we show that Us1.5 expression is independent of full length ICP22. In addition, we demonstrate that the reported Us1.5 start sites, M147 and M171 are incorrect and that Us1.5 initiates translation at M90 of the ICP22 ORF. Mutation of M90 to alanine resulted in loss of Us1.5 expression but had no effect on expression of the full length protein. We introduced the M90A mutation into the viral genome and, as observed in transfected cells, Us1.5 expression was greatly reduced in M90A-infected cells. Although Us1.5 expression was greatly reduced, the M90A mutant replicated efficiently in restrictive Rab-9 cells and levels of the late gene gC accumulated to WT levels. Collectively, this dissertation describes multiple systems to transiently express ICP22. Using this system we mapped the true start site of the Us1.5 protein and raised questions to the origin of Us1.5 protein expression.

Book Characterization of the Herpes Simplex Virus Type 2 UL45 Protein

Download or read book Characterization of the Herpes Simplex Virus Type 2 UL45 Protein written by Adam S. Cockrell and published by . This book was released on 1997 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Characterization of the Role of Herpes Simplex Virus Protein VP16 in Viral Gene Expression Through Interactions with the Virion Host Shutoff Protein  VHS  and HCF 1  microform

Download or read book Characterization of the Role of Herpes Simplex Virus Protein VP16 in Viral Gene Expression Through Interactions with the Virion Host Shutoff Protein VHS and HCF 1 microform written by Jozo Knez and published by Library and Archives Canada = Bibliothèque et Archives Canada. This book was released on 2003 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herpes Simplex Virus 1 (HSV1) VP16 transcriptionally activates viral immediate-early (IE) genes, through the formation of a multi-protein structure termed the VP16-induced complex (VIC). VIC is comprised of cellular transcription factors Oct-1 and HCF-1. In addition, VP16 is a pre-formed, structural protein that has a critical role in virion assembly. At least one aspect of its role at late times post-infection includes the downregulation of the virion host shutoff protein (vhs); which functions to indiscriminately degrade mRNA.

Book Identification and Characterization of the UL37 Protein of Herpes Simplex Virus Type 1 and Demonstration that it Interacts with ICP8  the Major DNA Binding Protein of Herpes Simplex Virus

Download or read book Identification and Characterization of the UL37 Protein of Herpes Simplex Virus Type 1 and Demonstration that it Interacts with ICP8 the Major DNA Binding Protein of Herpes Simplex Virus written by Lisa S. G. Shelton and published by . This book was released on 1992 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Identification and Characterization of the Protein Encoded by Gene UL49A of Herpes Simplex Virus Type 1  and Investigation of Its Role in the Virus Life Cycle

Download or read book Identification and Characterization of the Protein Encoded by Gene UL49A of Herpes Simplex Virus Type 1 and Investigation of Its Role in the Virus Life Cycle written by Ralph Adams (Ph.D.) and published by . This book was released on 1999 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: