Download or read book A Special Issue on Computational Modeling and Simulation of Infectious Diseases written by Tarek I. Zohdi and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microbial Threats to Health written by Institute of Medicine and published by National Academies Press. This book was released on 2003-08-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Download or read book Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases written by Dongmei Chen and published by John Wiley & Sons. This book was released on 2014-12-31 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Features modern research and methodology on the spread of infectious diseases and showcases a broad range of multi-disciplinary and state-of-the-art techniques on geo-simulation, geo-visualization, remote sensing, metapopulation modeling, cloud computing, and pattern analysis Given the ongoing risk of infectious diseases worldwide, it is crucial to develop appropriate analysis methods, models, and tools to assess and predict the spread of disease and evaluate the risk. Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features mathematical and spatial modeling approaches that integrate applications from various fields such as geo-computation and simulation, spatial analytics, mathematics, statistics, epidemiology, and health policy. In addition, the book captures the latest advances in the use of geographic information system (GIS), global positioning system (GPS), and other location-based technologies in the spatial and temporal study of infectious diseases. Highlighting the current practices and methodology via various infectious disease studies, Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases features: Approaches to better use infectious disease data collected from various sources for analysis and modeling purposes Examples of disease spreading dynamics, including West Nile virus, bird flu, Lyme disease, pandemic influenza (H1N1), and schistosomiasis Modern techniques such as Smartphone use in spatio-temporal usage data, cloud computing-enabled cluster detection, and communicable disease geo-simulation based on human mobility An overview of different mathematical, statistical, spatial modeling, and geo-simulation techniques Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases is an excellent resource for researchers and scientists who use, manage, or analyze infectious disease data, need to learn various traditional and advanced analytical methods and modeling techniques, and become aware of different issues and challenges related to infectious disease modeling and simulation. The book is also a useful textbook and/or supplement for upper-undergraduate and graduate-level courses in bioinformatics, biostatistics, public health and policy, and epidemiology.
Download or read book Computational Epidemiology written by Ellen Kuhl and published by Springer Nature. This book was released on 2021-09-22 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative textbook brings together modern concepts in mathematical epidemiology, computational modeling, physics-based simulation, data science, and machine learning to understand one of the most significant problems of our current time, the outbreak dynamics and outbreak control of COVID-19. It teaches the relevant tools to model and simulate nonlinear dynamic systems in view of a global pandemic that is acutely relevant to human health. If you are a student, educator, basic scientist, or medical researcher in the natural or social sciences, or someone passionate about big data and human health: This book is for you! It serves as a textbook for undergraduates and graduate students, and a monograph for researchers and scientists. It can be used in the mathematical life sciences suitable for courses in applied mathematics, biomedical engineering, biostatistics, computer science, data science, epidemiology, health sciences, machine learning, mathematical biology, numerical methods, and probabilistic programming. This book is a personal reflection on the role of data-driven modeling during the COVID-19 pandemic, motivated by the curiosity to understand it.
Download or read book Computational Modeling of Infectious Disease written by Chris von Csefalvay and published by Elsevier. This book was released on 2023-02-14 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world. Connects computational infectious disease analysis to state-of-the-art data science Conveys ideas on epidemiology and infectious disease modeling in a clear, accessible way Provides code examples to elucidate best practices
Download or read book Modeling and Simulation of Infectious Diseases written by Tarek I. Zohdi and published by Springer Nature. This book was released on 2023-02-09 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic that started in 2019-2020 has led to a gigantic increase in modeling and simulation of infectious diseases. There are numerous topics associated with this epoch-changing event, such as (a) disease propagation, (b) transmission, (c) decontamination, and (d) vaccines. This is an evolving field. The targeted objective of this book is to expose researchers to key topics in this area, in a very concise manner. The topics selected for discussion have evolved with the progression of the pandemic. Beyond the introductory chapter on basic mathematics, optimization, and machine learning, the book covers four themes in modeling and simulation infectious diseases, specifically: Part 1: Macroscale disease propagation, Part 2: Microscale disease transmission and ventilation system design, Part 3: Ultraviolet viral decontamination, and Part 4: Vaccine design and immune response. It is important to emphasize that the rapid speed at which the simulations operate makes the presented computational tools easily deployable as digital twins, i.e., digital replicas of complex systems that can be inexpensively and safely optimized in a virtual setting and then used in the physical world afterward, thus reducing the costs of experiments and also accelerating development of new technologies.
Download or read book Charting the Next Pandemic written by Ana Pastore y Piontti and published by Springer. This book was released on 2018-11-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the computational and complex systems modeling of the global spreading of infectious diseases. The latest developments in the area of contagion processes modeling are discussed, and readers are exposed to real world examples of data-model integration impacting the decision-making process. Recent advances in computational science and the increasing availability of real-world data are making it possible to develop realistic scenarios and real-time forecasts of the global spreading of emerging health threats. The first part of the book guides the reader through sophisticated complex systems modeling techniques with a non-technical and visual approach, explaining and illustrating the construction of the modern framework used to project the spread of pandemics and epidemics. Models can be used to transform data to knowledge that is intuitively communicated by powerful infographics and for this reason, the second part of the book focuses on a set of charts that illustrate possible scenarios of future pandemics. The visual atlas contained allows the reader to identify commonalities and patterns in emerging health threats, as well as explore the wide range of models and data that can be used by policy makers to anticipate trends, evaluate risks and eventually manage future events. Charting the Next Pandemic puts the reader in the position to explore different pandemic scenarios and to understand the potential impact of available containment and prevention strategies. This book emphasizes the importance of a global perspective in the assessment of emerging health threats and captures the possible evolution of the next pandemic, while at the same time providing the intelligence needed to fight it. The text will appeal to a wide range of audiences with diverse technical backgrounds.
Download or read book Computational Modeling Of The Covid 19 Disease Numerical Ode Analysis With R Programming written by William E Schiesser and published by World Scientific. This book was released on 2020-06-16 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is intended for readers who are interested in learning about the use of computer-based modelling of the COVID-19 disease. It provides a basic introduction to a five-ordinary differential equation (ODE) model by providing a complete statement of the model, including a detailed discussion of the ODEs, initial conditions and parameters, followed by a line-by-line explanation of a set of R routines (R is a quality, scientific programming system readily available from the Internet). The reader can access and execute these routines without having to first study numerical algorithms and computer coding (programming) and can perform numerical experimentation with the model on modest computers.
Download or read book Methods of Mathematical Modelling written by Harendra Singh and published by Academic Press. This book was released on 2022-06-10 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of Mathematical Modeling: Infectious Diseases presents computational methods related to biological systems and their numerical treatment via mathematical tools and techniques. Edited by renowned experts in the field, Dr. Hari Mohan Srivastava, Dr. Dumitru Baleanu, and Dr. Harendra Singh, the book examines advanced numerical methods to provide global solutions for biological models. These results are important for medical professionals, biomedical engineers, mathematicians, scientists and researchers working on biological models with real-life applications. The authors deal with methods as well as applications, including stability analysis of biological models, bifurcation scenarios, chaotic dynamics, and non-linear differential equations arising in biology. The book focuses primarily on infectious disease modeling and computational modeling of other real-world medical issues, including COVID-19, smoking, cancer and diabetes. The book provides the solution of these models so as to provide actual remedies. - Includes mathematical modeling for a variety of infectious diseases and disease processes, including SIR/SIRA, COVID-19, cancer, smoking and diabetes - Offers a complete and foundational understanding of modeling algorithms and techniques such as stability analysis, bifurcation scenarios, chaotic dynamics, and non-linear differential equations - Provides readers with datasets for applied learning of the various algorithms and modeling techniques
Download or read book Modeling and Dynamics of Infectious Diseases written by Zhien Ma and published by World Scientific. This book was released on 2009 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a systematic introduction to the fundamental methods and techniques and the frontiers of ? along with many new ideas and results on ? infectious disease modeling, parameter estimation and transmission dynamics. It provides complementary approaches, from deterministic to statistical to network modeling; and it seeks viewpoints of the same issues from different angles, from mathematical modeling to statistical analysis to computer simulations and finally to concrete applications.
Download or read book New Horizons in Modeling and Simulation for Social Epidemiology and Public Health written by Daniel Kim and published by John Wiley & Sons. This book was released on 2021-01-28 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to state-of-the-art modeling and simulation approaches for social and economic determinants of population health New Horizons in Modeling and Simulation for Social Epidemiology and Public Health offers a comprehensive introduction to modeling and simulation that addresses the many complex research questions in social epidemiology and public health. This book highlights a variety of practical applications and illustrative examples with a focus on modeling and simulation approaches for the social and economic determinants of population health. The book contains classic case examples in agent-based modeling (ABM) as well as essential information on ABM applications to public health including for infectious disease modeling, obesity, and tobacco control. This book also surveys applications of microsimulation (MSM) including of tax-benefit policies to project impacts of the social determinants of health. Specifically, this book: Provides an overview of the social determinants of health and the public health significance of addressing the social determinants of health Gives a conceptual foundation for the application of ABM and MSM to study the social determinants of health Offers methodological introductions to both ABM and MSM approaches with illustrative examples Includes cutting-edge systematic reviews of empirical applications of ABM and MSM in the social sciences, social epidemiology, and public health Discusses future directions for empirical research using ABM and MSM, including integrating aspects of both ABM and MSM and implications for public health policies Written for a broad audience of policy analysts, public planners, and researchers and practitioners in public health and public policy including social epidemiologists, New Horizons in Modeling and Simulation for Social Epidemiology and Public Health offers a fundamental guide to the social determinants of health and state-of-the-art applications of ABM and MSM to studying the social and economic determinants of population health.
Download or read book Computational Aerodynamic Modeling of Aerospace Vehicles written by Mehdi Ghoreyshi and published by MDPI. This book was released on 2019-03-08 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, the use of computational fluid dynamics (CFD) solutions is considered as the state-of-the-art in the modeling of unsteady nonlinear flow physics and offers an early and improved understanding of air vehicle aerodynamics and stability and control characteristics. This Special Issue covers recent computational efforts on simulation of aerospace vehicles including fighter aircraft, rotorcraft, propeller driven vehicles, unmanned vehicle, projectiles, and air drop configurations. The complex flow physics of these configurations pose significant challenges in CFD modeling. Some of these challenges include prediction of vortical flows and shock waves, rapid maneuvering aircraft with fast moving control surfaces, and interactions between propellers and wing, fluid and structure, boundary layer and shock waves. Additional topic of interest in this Special Issue is the use of CFD tools in aircraft design and flight mechanics. The problem with these applications is the computational cost involved, particularly if this is viewed as a brute-force calculation of vehicle’s aerodynamics through its flight envelope. To make progress in routinely using of CFD in aircraft design, methods based on sampling, model updating and system identification should be considered.
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1990 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modelling and Simulation of Human Environment Interactions written by Philippe J Giabbanelli and published by Mdpi AG. This book was released on 2021-12-31 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational models provide intelligent environmental decision support systems to understand how human decisions are shaped by, and contribute to changes in, the environment. These models provide essential tools to tackle the important issues raised by climate change, including migrations and conflicts due to resource scarcity (e.g., water resources), while accounting for the necessity of co-managing ecosystems across a population of stakeholders with diverse goals. Such socio-environmental systems are characterized by their complexity, which is reflected by an abundance of open questions. This book explores several of these open questions, based on the contributions from over 50 authors. The book starts with a review of quantitative methods to model human responses to changes in water resources availability. Water resources are then examined comprehensively from a data science lens, focusing on the creation of an ambitious interdisciplinary platform to facilitate data collection and analysis across hundreds of variables. The feasibility of using novel data sources to create detailed models of socio-environmental systems is further exemplified via a study integrating real-time sensor data into an agent-based model, thus illustrating the two growing research themes of Internet of Things (IoT) and smart cities. As the development of a smart city represents only one of several possible futures, we complement this study with a scenario focused on urban shrinkage, thus illustrating the flexibility of agent-based models at representing different dynamic phenomena in the context of socio-environmental systems. To stress the importance of engaging local stakeholders in managing these systems, we also show how human factors can be included in modeling studies via mixed methods, by transforming the mental models of individuals into rules for agent-based models. While several books account for methodological developments in modeling socio-environmental systems, our book is unique in combining case studies, methodological innovations, and a holistic approach to training the next generation of modelers. One chapter covers the ontological, epistemological, and ethical issues raised at the intersection of sustainability research and social simulation. In another chapter, we show that the benefits of simulations are not limited to managing complex eco-systems, as they can also serve an educational mission in teaching essential rules and thus improve systems thinking competencies in the broader population.
Download or read book Computational Immunology written by Josep Bassaganya-Riera and published by Academic Press. This book was released on 2015-10-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting
Download or read book Mathematics for Healthcare written by Krasimira Tsaneva-Atanasova and published by Frontiers Media SA. This book was released on 2018-09-28 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1996, and with extraordinary prescience, Panfilov and Holden had highlighted in their seminal book 'Computational Biology of the Heart' that biology was, potentially, the most mathematical of all sciences. Fast-forward 20 years and we have seen an explotion of applications of mathematics in not only biology, but healthcare that has already produced significant breakthroughs not imaginable more than 20 years ago. Great strides have been made in explaining through quantitative methods the underlying mechanisms of human disease, not without considerable ingenuity and effort. Biological mechanisms are bewildering: complex, ever evolving, multi-scale, variable, difficult to fully access and understand. This poses immense challenges to the computational physiology community that, nevertheless, has developed an impressive arsenal of tools and methods in a vertiginous race to combat disease with the tall order of improving human healthcare. Mechanistic models are now contending with the advent of machine learning in healthcare and the hope is that both approaches will be used synergistically since the complexity of human patophysiology and the difficulty of acquiring human datasets will require both, deductive and inductive methods. This Research Topic presents work that is currently at the frontier in computational physiology with a striking range of applications, from diabetes to graft failure and using a multitude of mathematical tools. This collection of articles represents a snapshot in a field that is moving a dizzying speed, bringing understanding of fundamental mechanism and solutions to healthcare problems experienced by healthcare systems all over the world.
Download or read book Agent based Simulation Modeling and Analysis of Infectious Disease Epidemics and Implications for Policy written by Parasto Alsadat Kasaie Sharifi and published by . This book was released on 2014 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the largest killers of children and young adults in developing countries, and continue to pose a high burden on global health. This dissertation concerns related topics for combating infectious-disease epidemics, and is organized into three main chapters. While each chapter revolves around a specific topic in the general domain of public-health policymaking, the unifying theme of this research is using agent-based simulation methodology for modeling and analysis of infectious-disease epidemics. The first chapter targets the topic of how best to allocate constrained resources to control an epidemic. In this study, we use a collection of computational techniques, including computer simulation and numerical optimization algorithms, to develop a simulation-optimization framework for addressing the resource-allocation problem as applied to an epidemic. The goal is to relax the restrictive assumptions held by traditional analytical approaches, thereby facilitating a more valid model that is necessarily more complex, and to extend the method to support a general class of resource-allocation problems with realistic assumptions about population structure, disease description, and interventions. The second chapter presents a series of studies on transmission dynamics of tuberculosis (TB), and addresses the impact of various control strategies for combating TB epidemics. Using an agent-based simulation model of a TB epidemic in a household-structured population, we estimate the timing of TB transmission among household and community members. Moreover, we consider multiple case-finding strategies, including household contact tracing and a community active approach, and evaluate the population-level impact of each intervention for controlling disease incidence. Finally, the third chapter analyzes estimation bias of the recent-transmission rate in molecular studies of TB. Analysis of population-based DNA data continues to serve as the main method to estimate the proportion of TB incidence due to recent transmission, which in turn has important implications for understanding the dynamics of transmission and policymaking. Previous studies have identified a number of factors affecting the precision of this approach in various settings, but the exact relationship of such factors remains uncertain. In this study, we aim to quantify the role of such factors, and develop a decision tool for adjusting the estimated ratio of infection due to recent transmission. Using an agent-based simulation model of TB as a virtual laboratory, we implement a sequence of statistically controlled experiments with regard to combinations of several factors. The results enable us to compute the estimation bias for various levels of each factor, and can serve as a decision-support tool for adjusting the estimation error in future molecular studies of TB. In summary, this dissertation concerns critical global-health issues in understanding, controlling, and policy-making concerning infectious-disease epidemics, and offers a multidisciplinary approach to such problems using advanced computer-simulation techniques and analytical tools. The agent-based simulation approach is a novel technique that is increasing in popularity across the literature and in several fields. This brings to bear the power and effectiveness of such models in various applications, and their promising contributions for control and policymaking of infectious diseases.
