Download or read book A Researcher s Guide To International Space Station Microbial Research written by National Aeronauti Space Administration and published by Independently Published. This book was released on 2019-03-04 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orbiting the Earth at almost 5 miles per second, a structure exists that is nearly the size of a football field and weighs almost a million pounds. The International Space Station (ISS) is a testament to international cooperation and significant achievements in engineering. Beyond all of this, the ISS is a truly unique research platform. The possibilities of what can be discovered by conducting research on the ISS are endless and have the potential to contribute to the greater good of life on Earth and inspire generations of researchers to come. As we increase utilization of ISS as a National Laboratory, now is the time for investigators to propose new research and to make discoveries unveiling novel responses that could not be defined using traditional approaches on Earth.
Download or read book Recapturing a Future for Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2012-01-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than four decades have passed since a human first set foot on the Moon. Great strides have been made in our understanding of what is required to support an enduring human presence in space, as evidenced by progressively more advanced orbiting human outposts, culminating in the current International Space Station (ISS). However, of the more than 500 humans who have so far ventured into space, most have gone only as far as near-Earth orbit, and none have traveled beyond the orbit of the Moon. Achieving humans' further progress into the solar system had proved far more difficult than imagined in the heady days of the Apollo missions, but the potential rewards remain substantial. During its more than 50-year history, NASA's success in human space exploration has depended on the agency's ability to effectively address a wide range of biomedical, engineering, physical science, and related obstacles-an achievement made possible by NASA's strong and productive commitments to life and physical sciences research for human space exploration, and by its use of human space exploration infrastructures for scientific discovery. The Committee for the Decadal Survey of Biological and Physical Sciences acknowledges the many achievements of NASA, which are all the more remarkable given budgetary challenges and changing directions within the agency. In the past decade, however, a consequence of those challenges has been a life and physical sciences research program that was dramatically reduced in both scale and scope, with the result that the agency is poorly positioned to take full advantage of the scientific opportunities offered by the now fully equipped and staffed ISS laboratory, or to effectively pursue the scientific research needed to support the development of advanced human exploration capabilities. Although its review has left it deeply concerned about the current state of NASA's life and physical sciences research, the Committee for the Decadal Survey on Biological and Physical Sciences in Space is nevertheless convinced that a focused science and engineering program can achieve successes that will bring the space community, the U.S. public, and policymakers to an understanding that we are ready for the next significant phase of human space exploration. The goal of this report is to lay out steps and develop a forward-looking portfolio of research that will provide the basis for recapturing the excitement and value of human spaceflight-thereby enabling the U.S. space program to deliver on new exploration initiatives that serve the nation, excite the public, and place the United States again at the forefront of space exploration for the global good.
Download or read book Researcher s Guide To written by National Aeronautics and Space Administration and published by Government Printing Office. This book was released on 2014-06-15 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the International Space Station Program Science Office 15-book Researchers Guide Series by discipline. The purpose of the series is to educate potential users of the ISS platform on how their ground-based experiments can be translated to the space environment. Each guide is designed to start the conversation of how new researchers can find opportunities as well as assistance in the proposal development process.
Download or read book Life and Physical Sciences Research for a New Era of Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2010-07-23 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to requests from Congress, NASA asked the National Research Council to undertake a decadal survey of life and physical sciences in microgravity. Developed in consultation with members of the life and physical sciences communities, the guiding principle for the study is to set an agenda for research for the next decade that will allow the use of the space environment to solve complex problems in life and physical sciences so as to deliver both new knowledge and practical benefits for humankind as we become a spacefaring people. The project's statement of task calls for delivery of two books-an interim report and a final survey report. Although the development of specific recommendations is deferred until the final book, this interim report does attempt to identify programmatic needs and issues to guide near-term decisions that are critical to strengthening the organization and management of life and physical sciences research at NASA.
Download or read book Microbiomes of the Built Environment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-06 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: People's desire to understand the environments in which they live is a natural one. People spend most of their time in spaces and structures designed, built, and managed by humans, and it is estimated that people in developed countries now spend 90 percent of their lives indoors. As people move from homes to workplaces, traveling in cars and on transit systems, microorganisms are continually with and around them. The human-associated microbes that are shed, along with the human behaviors that affect their transport and removal, make significant contributions to the diversity of the indoor microbiome. The characteristics of "healthy" indoor environments cannot yet be defined, nor do microbial, clinical, and building researchers yet understand how to modify features of indoor environmentsâ€"such as building ventilation systems and the chemistry of building materialsâ€"in ways that would have predictable impacts on microbial communities to promote health and prevent disease. The factors that affect the environments within buildings, the ways in which building characteristics influence the composition and function of indoor microbial communities, and the ways in which these microbial communities relate to human health and well-being are extraordinarily complex and can be explored only as a dynamic, interconnected ecosystem by engaging the fields of microbial biology and ecology, chemistry, building science, and human physiology. This report reviews what is known about the intersection of these disciplines, and how new tools may facilitate advances in understanding the ecosystem of built environments, indoor microbiomes, and effects on human health and well-being. It offers a research agenda to generate the information needed so that stakeholders with an interest in understanding the impacts of built environments will be able to make more informed decisions.
Download or read book Biotechnology in Space written by Günter Ruyters and published by Springer. This book was released on 2017-12-21 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the early successes, drawbacks and accomplishments in cell biology and cell biotechnology achieved by the latest projects performed on the International Space Station ISS. It also depicts outcomes of experiments in tissue engineering, cancer research and drug design and reveals the chances that research in Space offers for medical application on Earth. This SpringerBriefs volume provides an overview on the latest international activities in Space and gives an outlook on the potential of biotechnological research in Space in future. This volume is written for students and researchers in Biomedicine, Biotechnology and Pharmacology and may specifically be of interest to scientists with focus on protein sciences, crystallization, tissue engineering, drug design and cancer research.
Download or read book Astrobiology written by Gerda Horneck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges a gap in the literature by bringing together leading specialists from different backgrounds. It addresses the specific need for a readable book on this very interdisciplinary and new topic at research level.
Download or read book The International Space Station written by Robert C. Dempsey and published by Government Printing Office. This book was released on 2017 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looks at the operations of the International Space Station from the perspective of the Houston flight control team, under the leadership of NASA's flight directors, who authored the book. The book provides insight into the vast amount of time and energy that these teams devote to the development, planning and integration of a mission before it is executed. The passion and attention to detail of the flight control team members, who are always ready to step up when things do not go well, is a hallmark of NASA human spaceflight operations. With tremendous support from the ISS program office and engineering community, the flight control team has made the International Space Station and the programs before it a success.
Download or read book Assessment of Treatment Plant Performance and Water Quality Data A Guide for Students Researchers and Practitioners written by Marcos von Sperling and published by IWA Publishing. This book was released on 2020-01-15 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the basic principles for evaluating water quality and treatment plant performance in a clear, innovative and didactic way, using a combined approach that involves the interpretation of monitoring data associated with (i) the basic processes that take place in water bodies and in water and wastewater treatment plants and (ii) data management and statistical calculations to allow a deep interpretation of the data. This book is problem-oriented and works from practice to theory, covering most of the information you will need, such as (a) obtaining flow data and working with the concept of loading, (b) organizing sampling programmes and measurements, (c) connecting laboratory analysis to data management, (e) using numerical and graphical methods for describing monitoring data (descriptive statistics), (f) understanding and reporting removal efficiencies, (g) recognizing symmetry and asymmetry in monitoring data (normal and log-normal distributions), (h) evaluating compliance with targets and regulatory standards for effluents and water bodies, (i) making comparisons with the monitoring data (tests of hypothesis), (j) understanding the relationship between monitoring variables (correlation and regression analysis), (k) making water and mass balances, (l) understanding the different loading rates applied to treatment units, (m) learning the principles of reaction kinetics and reactor hydraulics and (n) performing calibration and verification of models. The major concepts are illustrated by 92 fully worked-out examples, which are supported by 75 freely-downloadable Excel spreadsheets. Each chapter concludes with a checklist for your report. If you are a student, researcher or practitioner planning to use or already using treatment plant and water quality monitoring data, then this book is for you! 75 Excel spreadsheets are available to download.
Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
Download or read book Grand Challenges in Fungal Biotechnology written by Helena Nevalainen and published by Springer Nature. This book was released on 2020-01-08 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive overview of the major applications and potential of fungal biotechnology. The respective chapters report on the latest advances and opportunities in each topic area, proposing new and sustainable solutions to some of the major challenges faced by modern society. Aimed at researchers and biotechnologists in academia and industry, it represents essential reading for anyone interested in fungal biotechnology, as well as those working within the broader area of microbial biotechnology. Written in an accessible language, the book also offers a valuable reference resource for decision-makers in government and at non-governmental organizations who are involved in the development of cleaner technologies and the global bioeconomy. The 21st century is characterized by a number of critical challenges in terms of human health, developing a sustainable bioeconomy, facilitating agricultural production, and establishing practices that support a cleaner environment. While there are chemical solutions to some of these challenges, developing bio-based approaches is becoming increasingly important. Filamentous fungi, ‘the forgotten kingdom,’ are a group of unique organisms whose full potential has yet to be revealed. Some key properties, such as their exceptional capacity to secrete proteins into the external environment, have already been successfully harnessed for the production of industrial enzymes and cellulosic biofuels. Many further aspects discussed here –such as feeding the hungry with fungal protein, and the potential applications of the various small molecules produced by fungi –warrant further exploration. In turn, the book covers the use of fungal cell factories to produce foreign molecules, e.g. for therapeutics. Strategies including molecular approaches to strain improvement, and recent advances in high-throughput technologies, which are key to finding better products and producers, are also addressed. Lastly, the book discusses the advent of synthetic biology, which is destined to greatly expand the scope of fungal biotechnology. The chapter “Fungal Biotechnology in Space: Why and How?” is available open access under a Creative Commons Attribution 4.0 International License at link.springer.com.
Download or read book Problems of Space Biology written by and published by . This book was released on 1973 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2003-08-22 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.
Download or read book Guide to Best Practices for Ocean Acidification Research and Data Reporting written by and published by . This book was released on 2011 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells written by Cheryl A. Nickerson and published by Springer. This book was released on 2016-05-21 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the physical force of gravity has shaped the architecture of all biological systems on our planet, spaceflight provides the opportunity to see life in a new adaptational mode - in response to reduced gravity. This enables investigations into the effects of the microgravity environment and associated changes in mechanical forces on mammalian cells/tissues and microbial pathogens, to bring novel insight into disease mechanisms, which are not discernable using conventional experimental approaches. Research using spaceflight platforms represents a paradigm shift in how we observe life processes and is on the leading edge of research discoveries into cellular and molecular mechanisms of health and disease. By incorporating the views of leading authors, this book highlights landmark discoveries and advances in mammalian cellular and microbiology research in both true spaceflight and ground-based spaceflight analogue environments for scientists and students alike who are interested in the influence of physical forces on mammalian and microbial cells, how this impacts transition between normal homeostasis and disease, and basic mechanisms of adaptation to low gravity environments. To provide a thorough understanding of this research, this book covers a range of topics including: (i) description the physical forces interacting with cells in microgravity and microgravity analogue environments, (ii) how alterations in these cellular forces impact human physiology, specifically immune function, (iii) use of these environments to develop organotypic three-dimensional (3-D) tissue culture models as predictive human surrogates for organogenesis and disease research, and (iv) microbial pathogen responses to culture in these environments, focusing on infectious disease Collectively, this information reflects a critical step in preparation for long-duration human space exploration, advances our knowledge of basic biological processes and mechanisms important to understand normal function and disease, and may lead to new strategies for treatment and prevention.
Download or read book Reference Guide to the International Space Station written by National Aeronautics and Space Administration and published by Government Printing Office. This book was released on 2015-11-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this edition, NASA provides an overview of the ISS, describe its research facilities and accommodations, and provide key information to conduct your experiments on this unique orbiting laboratory.
Download or read book Microbe Hunters written by Paul De Kruif and published by . This book was released on 1926 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1927.
