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EBookClubs

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Book Reproducibility and Replicability in Science

Download or read book Reproducibility and Replicability in Science written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-10-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Book Reproducible Research with R and RStudio

Download or read book Reproducible Research with R and RStudio written by Christopher Gandrud and published by CRC Press. This book was released on 2020-02-21 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for previous editions: "Gandrud has written a great outline of how a fully reproducible research project should look from start to finish, with brief explanations of each tool that he uses along the way... Advanced undergraduate students in mathematics, statistics, and similar fields as well as students just beginning their graduate studies would benefit the most from reading this book. Many more experienced R users or second-year graduate students might find themselves thinking, ‘I wish I’d read this book at the start of my studies, when I was first learning R!’...This book could be used as the main text for a class on reproducible research ..." (The American Statistician) Reproducible Research with R and R Studio, Third Edition brings together the skills and tools needed for doing and presenting computational research. Using straightforward examples, the book takes you through an entire reproducible research workflow. This practical workflow enables you to gather and analyze data as well as dynamically present results in print and on the web. Supplementary materials and example are available on the author’s website. New to the Third Edition Updated package recommendations, examples, URLs, and removed technologies no longer in regular use. More advanced R Markdown (and less LaTeX) in discussions of markup languages and examples. Stronger focus on reproducible working directory tools. Updated discussion of cloud storage services and persistent reproducible material citation. Added discussion of Jupyter notebooks and reproducible practices in industry. Examples of data manipulation with Tidyverse tibbles (in addition to standard data frames) and pivot_longer() and pivot_wider() functions for pivoting data. Features Incorporates the most important advances that have been developed since the editions were published Describes a complete reproducible research workflow, from data gathering to the presentation of results Shows how to automatically generate tables and figures using R Includes instructions on formatting a presentation document via markup languages Discusses cloud storage and versioning services, particularly Github Explains how to use Unix-like shell programs for working with large research projects

Book Potential Risks and Benefits of Gain of Function Research

Download or read book Potential Risks and Benefits of Gain of Function Research written by National Research Council and published by National Academies Press. This book was released on 2015-04-13 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.

Book Sybase 15 0 Replication Server Administration

Download or read book Sybase 15 0 Replication Server Administration written by Bagai and published by Jones & Bartlett Publishers. This book was released on 2008-12-08 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sybase 15 Replication Server Administration addresses the needs of a wide range of database professionals, explaining to both beginners and experts how to administer Sybase’s newest Replication Server release. This book examines all the knowledge, background information, and conceptual frameworks needed in order to get started on installing and administering Sybase Replication Server, and explores the world of contemporary cross-platform compatible Sybase Replication Server administration. Learn how to replicate business-critical data; configure database connections and routes; manage replicated tables, stored procedures, and subscriptions; set up a warm standby system; monitor replication performance and tune the database system; provide up-to-the-minute high availability of data; recover from failures and prevent data loss; troubleshoot the replication system.

Book Abridged Final Report with Resolutions and Recommendations

Download or read book Abridged Final Report with Resolutions and Recommendations written by World Meteorological Organization. Commission for Basic Systems and published by . This book was released on 1998 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Molecular Biology of The Cell

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Demonstration of Dissemination Practices on Special Class Instruction for the Mentally Retarded  A Report on functions and guidelines for replication

Download or read book Demonstration of Dissemination Practices on Special Class Instruction for the Mentally Retarded A Report on functions and guidelines for replication written by Edward L. Meyen and published by . This book was released on 1969 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Esthetics in Function

    Book Details:
  • Author : Marcelo A. Calamita
  • Publisher : Quintessenz Verlag
  • Release : 2023-10-10
  • ISBN : 3868676848
  • Pages : 907 pages

Download or read book Esthetics in Function written by Marcelo A. Calamita and published by Quintessenz Verlag. This book was released on 2023-10-10 with total page 907 pages. Available in PDF, EPUB and Kindle. Book excerpt: The esthetic harmony and effectiveness of occlusal function are integrated and are in constant movement in the search for balance. This book, written by a top expert in the field, is about the preservation and enhancement of smile esthetics. The richly illustrated content aims to enhance the clinician's understanding of the static and dynamic principles that act on a patient's stomatognathic system. The main themes of the book – treatment planning and occlusion – are inseparable factors for the success of every restorative treatment. It is only from a complete understanding of the varied and complex relationships between these aspects that the clinician can diagnose and treat a patient with a pragmatic and effective long-term approach. In a clear and uncomplicated manner, the book presents protocols containing all the relevant aspects related to the topic so that excellent results can be obtained with consistency and predictability. The content is based on an extensive literature review and contains the best-quality scientific evidence available at the time of publication, accompanied by the author's valuable commentary and notes.

Book Advanced R

    Book Details:
  • Author : Hadley Wickham
  • Publisher : CRC Press
  • Release : 2015-09-15
  • ISBN : 1498759807
  • Pages : 669 pages

Download or read book Advanced R written by Hadley Wickham and published by CRC Press. This book was released on 2015-09-15 with total page 669 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Essential Reference for Intermediate and Advanced R Programmers Advanced R presents useful tools and techniques for attacking many types of R programming problems, helping you avoid mistakes and dead ends. With more than ten years of experience programming in R, the author illustrates the elegance, beauty, and flexibility at the heart of R. The book develops the necessary skills to produce quality code that can be used in a variety of circumstances. You will learn: The fundamentals of R, including standard data types and functions Functional programming as a useful framework for solving wide classes of problems The positives and negatives of metaprogramming How to write fast, memory-efficient code This book not only helps current R users become R programmers but also shows existing programmers what’s special about R. Intermediate R programmers can dive deeper into R and learn new strategies for solving diverse problems while programmers from other languages can learn the details of R and understand why R works the way it does.

Book DNA Replication

    Book Details:
  • Author : Hisao Masai
  • Publisher : Springer
  • Release : 2018-01-22
  • ISBN : 9811069557
  • Pages : 581 pages

Download or read book DNA Replication written by Hisao Masai and published by Springer. This book was released on 2018-01-22 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest trends and future directions of DNA replication research. The contents reflect upon the principles that have been established through the genetic and enzymatic studies of bacterial, viral, and cellular replication during the past decades. The book begins with a historical overview of the studies on eukaryotic DNA replication by Professor Thomas Kelly, a pioneer of the field. The following chapters include genome-wide studies of replication origins and initiation factor binding, as well as the timing of DNA replications, mechanisms of initiation, DNA chain elongation and termination of DNA replication, the structural basis of functions of protein complexes responsible for execution of DNA replication, cell cycle-dependent regulation of DNA replication, the nature of replication stress and cells’ strategy to deal with the stress, and finally how all these phenomena are interconnected to genome instability and development of various diseases. By reviewing the existing concepts ranging from the old principles to the newest ideas, the book gives readers an opportunity to learn how the classical replication principles are now being modified and new concepts are being generated to explain how genome DNA replication is achieved with such high adaptability and plasticity. With the development of new methods including cryoelectron microscopy analyses of huge protein complexes, single molecular analyses of initiation and elongation of DNA replication, and total reconstitution of eukaryotic DNA replication with purified factors, the field is enjoying one of its most exciting moments, and this highly timely book conveys that excitement to all interested readers.

Book Evolution  Emerging Functions and Structure of Actin Binding Proteins

Download or read book Evolution Emerging Functions and Structure of Actin Binding Proteins written by Lei-Miao Yin and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Drug Utilization Research

    Book Details:
  • Author : Monique Elseviers
  • Publisher : John Wiley & Sons
  • Release : 2024-10-21
  • ISBN : 1119911656
  • Pages : 628 pages

Download or read book Drug Utilization Research written by Monique Elseviers and published by John Wiley & Sons. This book was released on 2024-10-21 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Towards a better understanding of how medicines are used in society Drug Utilization Research (DUR) is a discipline which combines aspects of pharmacotherapy, epidemiology, and health services research into an interdisciplinary set of methods for analyzing and assessing the prescribing, dispensing and consumption of medicines. It combines both qualitative and quantitative approaches to facilitate the safe and effective use of pharmaceuticals. Drug Utilization Research: Methods and Applications provides a comprehensive introduction to this discipline, prepared by an international team of authors with broad experience in numerous fields. Now reorganized and updated to reflect the latest research and global challenges, it is an indispensable resource for understanding the use of pharmaceuticals. Readers of the second edition of Drug Utilization Research will find: New chapters on methods, including more hands-on guidance on how to plan and conduct different types of drug utilization A section on specific applications in areas such as psychotropics, opioids, cancer drugs, antibacterials, and cardiovascular drugs A new section with case studies illustrating applications of DUR in different continents Detailed treatment of subjects including DUR and health policy, DUR in specific populations, and many more Drug Utilization Research is ideal for epidemiologists, pharmacists, physicians, nurses and others interested in drug use and its outcomes.

Book Cis and Trans Regulation of Transcription and Replication in BPV 1

Download or read book Cis and Trans Regulation of Transcription and Replication in BPV 1 written by Gary Lee Bream and published by . This book was released on 1990 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Smarter Business  Dynamic Information with IBM InfoSphere Data Replication CDC

Download or read book Smarter Business Dynamic Information with IBM InfoSphere Data Replication CDC written by Chuck Ballard and published by IBM Redbooks. This book was released on 2012-03-12 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: To make better informed business decisions, better serve clients, and increase operational efficiencies, you must be aware of changes to key data as they occur. In addition, you must enable the immediate delivery of this information to the people and processes that need to act upon it. This ability to sense and respond to data changes is fundamental to dynamic warehousing, master data management, and many other key initiatives. A major challenge in providing this type of environment is determining how to tie all the independent systems together and process the immense data flow requirements. IBM® InfoSphere® Change Data Capture (InfoSphere CDC) can respond to that challenge, providing programming-free data integration, and eliminating redundant data transfer, to minimize the impact on production systems. In this IBM Redbooks® publication, we show you examples of how InfoSphere CDC can be used to implement integrated systems, to keep those systems updated immediately as changes occur, and to use your existing infrastructure and scale up as your workload grows. InfoSphere CDC can also enhance your investment in other software, such as IBM DataStage® and IBM QualityStage®, IBM InfoSphere Warehouse, and IBM InfoSphere Master Data Management Server, enabling real-time and event-driven processes. Enable the integration of your critical data and make it immediately available as your business needs it.

Book Management

Download or read book Management written by and published by . This book was released on 1978 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Basics of Software Engineering Experimentation

Download or read book Basics of Software Engineering Experimentation written by Natalia Juristo and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basics of Software Engineering Experimentation is a practical guide to experimentation in a field which has long been underpinned by suppositions, assumptions, speculations and beliefs. It demonstrates to software engineers how Experimental Design and Analysis can be used to validate their beliefs and ideas. The book does not assume its readers have an in-depth knowledge of mathematics, specifying the conceptual essence of the techniques to use in the design and analysis of experiments and keeping the mathematical calculations clear and simple. Basics of Software Engineering Experimentation is practically oriented and is specially written for software engineers, all the examples being based on real and fictitious software engineering experiments.