Download or read book A Rational Approach to Pedal Cyclist Head Protection written by Bart Depreitere and published by Leuven University Press. This book was released on 2004 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. In western countries, head injury is a major cause of morbidity and mortality. While traumatic injuries are the leading cause of death under the age of 45 years, up to half of the trauma deaths and the majority of cases of permanent disability are directly related to a sustained head injury. In the U.S. an estimated 1.5 million people sustain head injury each year. As a result of these injuries, 50,000 people die, 230,000 people are hospitalized and survive and an estimated 80,000 - 90,000 people experience long-term disability. Contents include: Introduction, Aims of the Study, Analysis of Bicycle Accidents and the Resultant Head Injuries in a Study of 86 cases, Investigations on the Mechanics of Skull and Brain Injuries, Investigation of Bicycle Safety Helmet Performance in Impact Testing, General Discussion and Perspectives."
Download or read book Traffic Accidents written by Graham P. Bartley and published by Nova Publishers. This book was released on 2008 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines a wide range of issues related to traffic accidents including prevention, safety, prediction, precipitation, mitigation, and related law enforcement issues.
Download or read book Biocybernetics and Biomedical Engineering Current Trends and Challenges written by Dorota G. Pijanowska and published by Springer Nature. This book was released on 2022 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 13 chapters in which you can find various examples of the development of methods and/or systems supporting medical diagnostics and therapy, related to biomedical imaging, signal and image processing, biomechanics, biomaterials and artificial organs, modeling of biomedical systems, which, as the current research issues, were presented at the 22nd Polish BBE Conference held at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, in May 2021. Obviously, it is not easy to recommend an interdisciplinary book as it may seem inconsistent in some respects. This is the case here because it concerns the area of biocybernetics and biomedical engineering (BBE), which is not only an interdisciplinary but even multidisciplinary science. On the other hand, the scattered subject matter of the book is its advantage, as the book may be of interest to an advanced and wide range of readers and researchers representing both medical, biological and technical points of view.
Download or read book Innovations in Biomedical Engineering written by Marek Gzik and published by Springer Nature. This book was released on 2022-05-31 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest developments in the field of biomedical engineering and includes practical solutions and strictly scientific considerations. The development of new methods of treatment, advanced diagnostics or personalized rehabilitation requires close cooperation of experts from many fields, including, among others, medicine, biotechnology and finally biomedical engineering. The latter, combining many fields of science, such as computer science, materials science, biomechanics, electronics not only enables the development and production of modern medical equipment, but also participates in the development of new directions and methods of treatment. The presented monograph is a collection of scientific papers on the use of engineering methods in medicine. The topics of the work include both practical solutions and strictly scientific considerations expanding knowledge about the functioning of the human body. We believe that the presented works will have an impact on the development of the field of science, which is biomedical engineering, constituting a contribution to the discussion on the directions of development of cooperation between doctors, physiotherapists and engineers. We would also like to thank all the people who contributed to the creation of this monograph—both the authors of all the works and those involved in technical works.
Download or read book Neonatal Analgesia written by Karel Allegaert and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Between Facts and Norms written by Pascal Borry and published by Leuven University Press. This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book IUTAM Symposium on Impact Biomechanics From Fundamental Insights to Applications written by M. D. Gilchrist and published by Springer Science & Business Media. This book was released on 2005-06-30 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Substantial fundamental work has been undertaken in the different aspects of impact biomechanics over the past three decades. Much of this has been motivated and undertaken by the automotive industry in their efforts to improve transport safety. More recently, however, it has become apparent that the multidisciplinary synergies which are realised by interactions between engineers, scientists and clinical practitioners will ultimately lead to a greater understanding of the complex interacting phenomena within the human body after it has sustained an impact. In turn, this greater depth of knowledge will provide more fundamental insights into the analysis, diagnosis, treatment and prevention of impact injuries across a broader spectrum of accident environments. This book contains the edited papers of the IUTAM Symposium on the Biomechanics of Impact, which was held in University College Dublin, Ireland in July 2005. These papers can be grouped into those that are concerned with the different causes of accidents (e.g., transport, occupational and sports injuries), the mechanics involved in accident analysis (e.g., accident investigation, computational modelling techniques), the different types of resulting traumatic injuries (including musculoskeletal, organ, spinal and head injuries), methods of assessing the extent of injury (e.g., injury assessment, injury criteria, constitutive laws for human tissue), and providing protection during an impact (e.g., injury prevention, energy absorption materials, and safety devices). Researchers active in the area of biomechanics will find the book very useful in addressing recent developments in these areas.
Download or read book Structural and Functional Repercussions of Loss of Function and Clinical Mutants of Presenilin written by Omar Nyabi and published by Leuven University Press. This book was released on 2005 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease is a major health problem. The disease is clinically characterized by the progressive mental decline of the patients and pathologically by the accumulation of amyloid plaques and tangles and neurodegenerative changes in the brain. The cause of the disease remains unclear but in some cases, genetic (missense) mutations in the Amyloid Precursor Protein (APP) and in the Presenilin genes (PS1 & PS2) are sufficient to initiate the whole disease cascade. All these mutations cause in essence an increase in the generation or a change of the characteristics of the AB peptide making it more prone to produce amyloid plaques. The AB peptide is generated from the APP protein and the question how Presenilin influences APP processing and AB production is the main topic of our work.
Download or read book Context Dependency of Renin Anglotensin Aldosterone System Genes in Relation to Left Ventricular Structure written by Tatiana Kuznetsova and published by Leuven University Press. This book was released on 2004-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiological Study of Presenilins and Baces Two Proteases Involved in the Pathogenesis of Alzheimer s Disease written by Jos Tournoy and published by Leuven University Press. This book was released on 2006 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mouse Model for Chemical Induced Asthma written by Jeroen Vanoirbeek and published by Leuven University Press. This book was released on 2004-09 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization of the Glypican Receptor Receptor Function written by Bart De Cat and published by Leuven University Press. This book was released on 2004-09 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Measurement of CYP 3A4 and P GP Activity in Vivo Using Dynamic Breath and Urine Analysis written by Wim Lemahieu and published by Leuven University Press. This book was released on 2005 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Contents include: General introduction, Measurement of intestinal CYP3A4 and P-Glycoprotein activity by a combined oral and intravenous 14C-Erythromycin breath and urine test, Alterations of CYP3A4 and P-Glycoprotein activity in vivo with time in renal graft recipients, CYP3A4 and P-Glycoprotein activity in healthy controls and transplant patients on cyclosporine vs. Tacrolimus vs. Sirolimus, Impact of gastric acid suppressants on cytochrome P450 3A4 and P-Glycoprotein: consequences for FK506 assimilation, Diarrhoea after transplantation: impact on cytochrome P4503A4/P-Glycoprotein and assimilation of calcineurin inhibitors, Discussion.
Download or read book Role of Nitric Oxide Synthase in the Regulation of Pulmonary Vascular Tone written by Leifu Jiang and published by Leuven University Press. This book was released on 2006-09 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fatty Acid Synthase written by Ellen De Schrijver and published by Leuven University Press. This book was released on 2005 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty acid synthase (FAS) is a key lipogenic enzyme catalyzing the terminal steps in the synthesis of fatty acids. In the majority of normal tissues, FAS expression is low. In many human cancers, however, including cancer of the prostate, FAS expression and FAS activity are very high. As shown in the laboratory, overexpression of FAS in tumor cells is part of a more general and coordinate upregulation of multiple lipogenic genes caused, at least in part, by activation of sterol regulatory element binding proteins (SREBPs), transcription factors that play a key role in cellular lipid homeostasis. The mechanisms underlying the activation of the SREBP pathway and the increase in lipogenesis in tumor cells as well as the ultimate biological significance of this phenomenon remain poorly understood. Nonetheless there is evidence that overexpression of lipogenic genes occurs early in tumor development and that the degree of overexpression correlates with increasing tumor grade. Moreover, a number of studies suggest that inhibition of FAS selectively reduces proliferation of tumor cells and causes apoptosis, implying that FAS and other lipogenic enzymes may constitute interesting targets for antineoplastic therapy.
Download or read book Salivary and Mammary Gland Tumorigenesis in PLAG1 Transgenic Mice written by Isabella C. C. van Valckenborgh and published by Leuven University Press. This book was released on 2005 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Ph.D. dissertation. Contents include: Introduction: The normal salivary gland, Salivary gland tumors, Pleomorphic adenoma of the salivary glands, PLAG1, Unraveling human cancer using the mouse as a model system, Salivary gland transgenesis; Aims and Rationale; Material and Methods: Immunohistochemistry, Cytogenetic analysis, FISH analysis, Immunoflourescence, Cloning strategies, DNA sequencing, Transfections and luciferase assay, Western blot analysis, Generation of transgenic mouse strain by zygote micro-injection, PCR analysis, Isolation of RNA, Northern blot analysis, Isolation of DNA, Southern blot analysis, Labeling of DNA probes, Histology, Gene expression profiling; Results: Immunohistological localization studies of PLAG1 in human pleomorphic adenoma of the salivary gland, Human PLAG1 transgenic mouse strain, Study of PLAG1 and PLAGL2 target genes by microarray analysis; Discussion and Perspectives: Immunohistological localization studies of PLAG1 in the human pleomorphic adenoma of the salivary gland, Human PLAG1 transgenic mouse strain, Study of PLAG1 and PLAGL2 target genes by microarray analysis; General conclusions; Summary; References.
Download or read book A Prospective Study of Risk Factors for Low Back Disorders in Occupational Settings written by An van Nieuwenhuyse and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
