Download or read book A Polymer Cochlear Electrode Array Atraumatic Deep Insertion Tripolar Stimulation and Long Term Reliability written by Tae Mok Gwon and published by Springer. This book was released on 2018-05-24 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the design, fabrication and evaluation of a polymer-based neural interface for a cochlear electrode array, reviewed in terms of fabrication process, functionality, and reliability. Polymer-based devices have attracted attention in the neural prosthetic field due to their flexibility and compatibility with micro-fabrication process. A liquid crystal polymer (LCP) is an inert, highly water-resistant polymer suitable for the encapsulation of electronic components and as a substrate material for fabricating neural interfaces. The author has designed, fabricated, and evaluated an LCP-based cochlear electrode array for an improved polymer-based cochlear implant. The thesis deals with 3 key topics: atraumatic deep insertion, tripolar stimulation, and long-term reliability. Atraumatic insertion of the intracochlear electrode and resulting preservation of residual hearing have become essential in state–of-the-art cochlear implantation. A novel tapered design of an LCP-based cochlear electrode array is presented to meet such goals. For high-density and pitch-recognizable cochlear implant, channel interaction should be avoided. Local tripolar stimulation using multi-layered electrode sites are shown to achieve highly focused electrical stimulation. This thesis addresses another vital issue in the polymer-based neural implants: the long-term reliability issue. After suggesting a new method of forming mechanical interlocking to improve polymer-metal adhesion, the author performs accelerating aging tests to verify the method’s efficacy. The aforementioned three topics have been thoroughly examined through various in vitro and in vivo studies. Verification foresees the development of LCP-based cochlear electrode array for an atraumatic deep insertion, advanced stimulation, and long-term clinical implant.
Download or read book Deep Brain Stimulation Management written by William J. Marks, Jr and published by Cambridge University Press. This book was released on 2015-09-03 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.
Download or read book Auditory Prostheses written by Fan-Gang Zeng and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cochlear implants are currently the standard treatment for profound sensorineural hearing loss. In the last decade, advances in auditory science and technology have not only greatly expanded the utility of electric stimulation to other parts of the auditory nervous system in addition to the cochlea, but have also demonstrated drastic changes in the brain in responses to electric stimulation, including changes in language development and music perception. Volume 20 of SHAR focused on basic science and technology underlying the cochlear implant. However, due to the newness of the ideas and technology, the volume did not cover any emerging applications such as bilateral cochlear implants, combined acoustic-electric stimulation, and other types of auditory prostheses, nor did it review brain plasticity in responses to electric stimulation and its perceptual and language consequences. This proposed volume takes off from Volume 20, and expands the examination of implants into new and highly exciting areas. This edited book starts with an overview and introduction by Dr. Fan-Gang Zeng. Chapters 2-9 cover technological development and the advances in treating the full spectrum of ear disorders in the last ten years. Chapters 10-15 discuss brain responses to electric stimulation and their perceptual impact. This volume is particularly exciting because there have been quantum leap from the traditional technology discussed in Volume 20. Thus, this volume is timely and will be of real importance to the SHAR audience.
Download or read book Implantable Neural Prostheses 1 written by David Zhou and published by Springer Science & Business Media. This book was released on 2009-06-10 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has been made in the development of neural prostheses to restore human functions and improve the quality of human life. Biomedical engineers and neuroscientists around the world are working to improve design and performance of existing devices and to develop novel devices for artificial vision, artificial limbs, and brain–machine interfaces. This book, Implantable Neural Prostheses 1: Devices and Applications,ispart one of a two-book series and describes state-of-the-art advances in techniques associated with implantable neural prosthetic devices and their applications. Devices covered include sensory prosthetic devices, such as visual implants, cochlear implants, auditory midbrain implants, and spinal cord stimulators. Motor prosthetic devices, such as deep brain stimulators, Bion microstimu- tors, the brain control and sensing interface, and cardiac electro-stimulation devices are also included. Progress in magnetic stimulation that may offer a non-invasive approach to prosthetic devices is introduced. Regulatory approval of implantable medical devices in the United States and Europe is also discussed.
Download or read book Active Middle Ear Implants written by Klaus Böheim and published by Karger Medical and Scientific Publishers. This book was released on 2010 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, methods for coupling active implants to the middle ear, round window or combinations of passive middle ear prostheses have progressed considerably. Patient selection criteria have expanded from purely sensorineural hearing losses to conductive and mixed hearing losses in difficult-to-treat ears. This book takes into consideration recently developed methods as well as devices in current use. It begins with a fascinating and authentic history of active middle ear implants, written by one of the main pioneers in the field. In the following chapters, leading scientists and clinicians discuss the relevant topics in otology and audiology. Treatments for sensorineural hearing loss, conductive and mixed hearing losses, and results on alternative coupling sites such as the stapes footplate and the oval window are also covered, as well as articles on candidacy and cost-effectiveness. This publication is a must for ENT professionals and surgeons seeking out the latest knowledge on current research and clinical applications of active middle ear implants for all types of hearing loss.
Download or read book Translational Research in Audiology Neurotology and the Hearing Sciences written by Colleen G. Le Prell and published by Springer. This book was released on 2016-11-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the key steps that enable high-impact basic science to ultimately result in significant clinical advances that improve patient outcome. This volume will provide an overview of key issues in translation of research from “bedside to bench to bedside”, not only from the perspective of the key funding agencies, but also from the scientists and clinicians who are currently involved in the translational research process. It will attempt to offer insight into real-world experience with intellectual property and technology transfer activities that can help move auditory technologies ahead, as scientists and clinicians typically have little or no formal training in these areas. Translational Research in Audiology and the Hearing Sciences will be aimed at graduate students and postdoctoral investigators, as well as professionals and academics. It is intended to function as a high-profile and up-to-date reference work on Translational Research in the auditory sciences, emphasizing research programs in the traditional areas including drugs and devices, as well as less traditional, still emerging, areas such as sensorineural hearing loss, auditory processing disorder, cochlear implants and hearing aids, and tinnitus therapies.
Download or read book Implantable Electronic Medical Devices written by Dennis Fitzpatrick and published by Elsevier. This book was released on 2014-11-05 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implantable Electronic Medical Devices provides a thorough review of the application of implantable devices, illustrating the techniques currently being used together with overviews of the latest commercially available medical devices. This book provides an overview of the design of medical devices and is a reference on existing medical devices. The book groups devices with similar functionality into distinct chapters, looking at the latest design ideas and techniques in each area, including retinal implants, glucose biosensors, cochlear implants, pacemakers, electrical stimulation therapy devices, and much more. Implantable Electronic Medical Devices equips the reader with essential background knowledge on the application of existing medical devices as well as providing an introduction to the latest techniques being used. - A catalogue of existing implantable electronic medical devices - Up-to-date information on the design of implantable electronic medical devices - Background information and reviews on the application and design of up-to-date implantable electronic medical devices
Download or read book Binaural Hearing written by Ruth Y. Litovsky and published by Springer Nature. This book was released on 2021-03-01 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Binaural Hearing involves studies of auditory perception, physiology, and modeling, including normal and abnormal aspects of the system. Binaural processes involved in both sound localization and speech unmasking have gained a broader interest and have received growing attention in the published literature. The field has undergone some significant changes. There is now a much richer understanding of the many aspects that comprising binaural processing, its role in development, and in success and limitations of hearing-aid and cochlear-implant users. The goal of this volume is to provide an up-to-date reference on the developments and novel ideas in the field of binaural hearing. The primary readership for the volume is expected to be academic specialists in the diverse fields that connect with psychoacoustics, neuroscience, engineering, psychology, audiology, and cochlear implants. This volume will serve as an important resource by way of introduction to the field, in particular for graduate students, postdoctoral scholars, the faculty who train them and clinicians.
Download or read book Implantable Neuroprostheses for Restoring Function written by Kevin Kilgore and published by Elsevier. This book was released on 2015-02-24 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and developments in neuroprostheses are providing scientists with the potential to greatly improve the lives of individuals who have lost some function. Neuroprostheses can help restore or substitute motor and sensory functions which may have been damaged as a result of injury or disease. However, these minute implantable sensors also provide scientists with challenges. This important new book provides readers with a comprehensive review of neuroprostheses. Chapters in part one are concerned with the fundamentals of these devices. Part two looks at neuroprostheses for restoring sensory function whilst part three addresses neuroprostheses for restoring motor function. The final set of chapters discusses significant considerations concerning these sensors. - Systematic and comprehensive coverage of neuroprostheses - Covers the fundamentals of neuroprostheses, their application in restoring sensory and motor function and an analysis of the future trends - Keen focus on industry needs in the field of biomaterials
Download or read book Deep Brain Stimulation written by Peter Bain and published by Oxford University Press. This book was released on 2009-03-05 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides an overview of the use of deep brain stimulation (DBS) for the treatment of movement disorders as well as an introduction to the developing area of DBS for the management of psychiatric disease.
Download or read book Handbook of Innovations in Central Nervous System Regenerative Medicine written by António Salgado and published by Elsevier. This book was released on 2020-06-10 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Download or read book Prostheses for the Brain written by Andrej Kral and published by Elsevier. This book was released on 2021-04-09 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostheses for the Brain: Introduction to Neuroprosthetics bridges the disciplines required in the field of neuroprosthetics and provides the interdisciplinary base required for understanding neuroprosthetic devices. It introduces basic aspects from the physical, bioengineering and medical perspectives, and forms a common knowledge base. It provides the entrance to the field and sets realistic expectations, both regarding potentials as well as limitations, for the devices in both design and outcomes. The book additionally reviews the technology behind the most frequently used and most clinically successful neuroprosthetic devices. It provides the physiological background for their function, as well as the technology behind them. Finally, the authors suggest future possible developments that may play crucial role in new prostheses for the brain. This gives the reader a comprehensive view on the principles and applications of neuroprostheses. This book has been built from the authors course they teach on neuroprostheses and is ideal for students, engineers and medical professionals in this field. Introduces the general principles of conductivity of electrolytes and the processes at the tissue-electrode interface Describes safety issues and regulatory rules, clarifies conceptual differences between stimulating and sensing electrodes Reviews stimulation strategies, tissue reactions, potential medical complications, brain adaptations and the clinically most successful applications of neuroprostheses
Download or read book Comprehensive Microsystems written by Yogesh B. Gianchandani and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive reference available on Microelectromechanical Systems (MEMS). This set provides an exhaustive overview of the wide range of topics which comprise the microsystems field. This is essential reference for both academics and professionals in the field.
Download or read book The Siege written by Stephen White and published by Penguin. This book was released on 2009-08-04 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times bestselling author of Dead Time Disgraced Boulder detective Sam Purdy, FBI counter-terrorism specialist Christopher Poe, and CIA analyst Deirdre Drake are drawn to Yale University to investigate the disappearances of several students- including the sons of both the Secretary of the Army and a Supreme Court Justice. An unseen enemy is playing by no rules, making no demands, somehow anticipating every FBI move-and executing hostages, one by one...
Download or read book Bioimpedance and Bioelectricity Basics written by Orjan G. Martinsen and published by Academic Press. This book was released on 2014-08-14 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioimpedance and Bioelectricity Basics, 3rd Edition paves an easier and more efficient way for people seeking basic knowledge about this discipline. This book's focus is on systems with galvanic contact with tissue, with specific detail on the geometry of the measuring system. Both authors are internationally recognized experts in the field. The highly effective, easily followed organization of the second edition has been retained, with a new discussion of state-of-the-art advances in data analysis, modelling, endogenic sources, tissue electrical properties, electrodes, instrumentation and measurements. This book provides the basic knowledge of electrochemistry, electronic engineering, physics, physiology, mathematics, and model thinking that is needed to understand this key area in biomedicine and biophysics. - Covers tissue immittance from the ground up in an intuitive manner, supported with figures and examples - New chapters on electrodes and statistical analysis - Discusses in detail dielectric and electrochemical aspects, geometry and instrumentation as well as electrical engineering concepts of network theory, providing a cross-disciplinary resource for engineers, life scientists, and physicists
Download or read book Engineering in Medicine written by Paul A. Iaizzo and published by Academic Press. This book was released on 2018-11-07 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engineering in Medicine: Advances and Challenges documents the historical development, cutting-edge research and future perspectives on applying engineering technology to medical and healthcare challenges. The book has 22 chapters under 5 sections: cardiovascular engineering, neuroengineering, cellular and molecular bioengineering, medical and biological imaging, and medical devices.The challenges and future perspectives of engineering in medicine are discussed, with novel methodologies that have been implemented in innovative medical device development being described.This is an ideal general resource for biomedical engineering researchers at both universities and in industry as well as for undergraduate and graduate students. Presents a broad perspective on the state-of-the-art research in applying engineering technology to medical and healthcare challenges that cover cardiovascular engineering, neuroengineering, cellular and molecular bioengineering, medical and biological imaging, and medical devices Presents the challenges and future perspectives of engineering in medicine Written by members of the University of Minnesota’s prestigious Institute of Engineering in Medicine (IEM), in collaboration with other experts around the world
Download or read book Medical Device Technologies written by Gail D. Baura and published by Academic Press. This book was released on 2011-10-07 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Device Technologies introduces undergraduate engineering students to commonly manufactured medical devices. It is the first textbook that discusses both electrical and mechanical medical devices. The first 20 chapters are medical device technology chapters; the remaining eight chapters focus on medical device laboratory experiments. Each medical device chapter begins with an exposition of appropriate physiology, mathematical modeling or biocompatibility issues, and clinical need. A device system description and system diagram provide details on technology function and administration of diagnosis and/or therapy. The systems approach lets students quickly identify the relationships between devices. Device key features are based on five applicable consensus standard requirements from organizations such as ISO and the Association for the Advancement of Medical Instrumentation (AAMI). The medical devices discussed are Nobel Prize or Lasker Clinical Prize winners, vital signs devices, and devices in high industry growth areas Three significant Food and Drug Administration (FDA) recall case studies which have impacted FDA medical device regulation are included in appropriate device chapters Exercises at the end of each chapter include traditional homework problems, analysis exercises, and four questions from assigned primary literature Eight laboratory experiments are detailed that provide hands-on reinforcement of device concepts
